Entry: PS01248

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General information about the entry

Entry name [info] EGF_LAM_1
Accession [info] PS01248
Entry type [info] PATTERN
Date [info] NOV-1997 (CREATED); NOV-1997 (DATA UPDATE); JUL-2014 (INFO UPDATE).
PROSITE Doc. [info] PDOC00961

Name and characterization of the entry

Description [info] Laminin-type EGF-like (LE) domain signature.
Pattern [info]
C-x(1,2)-C-x(5)-G-x(2)-C-x(2)-C-x(3,4)-[FYW]-x(3,15)-C.

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2014_09 which contains 546'439 sequence entries.


Total number of hits 564 in 132 different sequences
Number of true positive hits 524 in 92 different sequences
Number of 'unknown' hits
Number of false positive hits 40 in 40 different sequences
Number of false negative sequences 1
Number of 'partial' sequences 1
Precision (true positives / (true positives + false positives)) 92.91 %
Recall (true positives / (true positives + false negatives)) 99.81 %

Comments [info]

Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 21
Site [info] disulfide at position 1
Site [info] disulfide at position 3
Site [info] disulfide at position 7
Site [info] disulfide at position 9
Site [info] disulfide at position 13
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
92 sequences

AGRIN_CHICK (P31696), AGRIN_DIPOM (Q90404), AGRIN_HUMAN (O00468), 
AGRIN_MOUSE (A2ASQ1), AGRIN_RAT   (P25304), ATRN1_HUMAN (Q5VV63), 
ATRN1_MOUSE (Q6A051), ATRN_HUMAN  (O75882), ATRN_MOUSE  (Q9WU60), 
ATRN_RAT    (Q99J86), CELR1_HUMAN (Q9NYQ6), CELR1_MOUSE (O35161), 
CELR2_HUMAN (Q9HCU4), CELR2_MOUSE (Q9R0M0), CELR2_RAT   (Q9QYP2), 
CELR3_HUMAN (Q9NYQ7), CELR3_MOUSE (Q91ZI0), CELR3_RAT   (O88278), 
EPI1_CAEEL  (Q21313), LAM2_CAEEL  (Q18823), LAMA1_HUMAN (P25391), 
LAMA1_MOUSE (P19137), LAMA2_HUMAN (P24043), LAMA2_MOUSE (Q60675), 
LAMA3_HUMAN (Q16787), LAMA3_MOUSE (Q61789), LAMA4_HUMAN (Q16363), 
LAMA4_MOUSE (P97927), LAMA5_HUMAN (O15230), LAMA5_MOUSE (Q61001), 
LAMA_DROME  (Q00174), LAMB1_CHICK (Q01635), LAMB1_DROME (P11046), 
LAMB1_HUMAN (P07942), LAMB1_HYDVU (Q27262), LAMB1_MOUSE (P02469), 
LAMB2_HUMAN (P55268), LAMB2_MOUSE (Q61292), LAMB2_RAT   (P15800), 
LAMB3_HUMAN (Q13751), LAMB3_MOUSE (Q61087), LAMB4_DANRE (Q8JHV6), 
LAMB4_HUMAN (A4D0S4), LAMB_HIRME  (Q25092), LAMC1_DANRE (Q1LVF0), 
LAMC1_DROME (P15215), LAMC1_HUMAN (P11047), LAMC1_MOUSE (P02468), 
LAMC1_XENTR (A0JP86), LAMC2_HORSE (Q8HZI9), LAMC2_HUMAN (Q13753), 
LAMC2_MOUSE (Q61092), LAMC3_HUMAN (Q9Y6N6), LAMC3_MOUSE (Q9R0B6), 
MEGF8_HUMAN (Q7Z7M0), MEGF8_MOUSE (P60882), MEGF8_RAT   (Q9QYP0), 
MEGF9_HUMAN (Q9H1U4), MEGF9_MOUSE (Q8BH27), NET1_CHICK  (Q90922), 
NET1_HUMAN  (O95631), NET1_MOUSE  (O09118), NET1_PIG    (Q2HXW4), 
NET1_RAT    (Q924Z9), NET3_CHICK  (Q90923), NET3_HUMAN  (O00634), 
NET3_MOUSE  (Q9R1A3), NET4_HUMAN  (Q9HB63), NET4_MOUSE  (Q9JI33), 
NET4_PONAB  (Q5RB89), NET5_HUMAN  (Q8WTR8), NET5_MOUSE  (Q3UQ22), 
NETA_DROME  (Q24567), NETB_DROME  (Q24568), NTNG1_HUMAN (Q9Y2I2), 
NTNG1_MOUSE (Q8R4G0), NTNG2_HUMAN (Q96CW9), NTNG2_MOUSE (Q8R4F1), 
PGBM_HUMAN  (P98160), PGBM_MOUSE  (Q05793), STAB1_HUMAN (Q9NY15), 
STAB1_MOUSE (Q8R4Y4), STAB2_HUMAN (Q8WWQ8), STAB2_MOUSE (Q8R4U0), 
STAB2_RAT   (Q8CFM6), STAN_DROME  (Q9V5N8), TAG53_CAEEL (Q19981), 
UNC52_CAEEL (Q06561), UNC6_CAEEL  (P34710), USH2A_HUMAN (O75445), 
USH2A_MOUSE (Q2QI47), USH2A_RAT   (Q8K3K1)
» More

UniProtKB/Swiss-Prot
False negative sequences
1 sequence

SIGK_DICDI  (Q6TMJ6)

		
UniProtKB/Swiss-Prot
'Partial' sequences
1 sequence

LAMBV_CHICK (Q01636)

		
UniProtKB/Swiss-Prot
False positive sequences
40 sequences

ADP1_YEAST  (P25371), CRE2A_XENLA (Q5XH36), CRE2B_XENLA (Q4V7M2), 
CREL1_BOVIN (Q5EA46), CREL1_HUMAN (Q96HD1), CREL1_MOUSE (Q91XD7), 
CREL1_RAT   (Q4V7F2), CREL2_BOVIN (Q2KIT5), CREL2_CRIGR (Q60438), 
CREL2_DANRE (Q7SXF6), CREL2_HUMAN (Q6UXH1), CREL2_MOUSE (Q9CYA0), 
CREL2_RAT   (Q4G063), POL_COYMV   (P19199), SRCH_HUMAN  (P23327), 
SRCH_RABIT  (P16230), TYRO_BOVIN  (Q8MIU0), TYRO_CANFA  (P54834), 
TYRO_CHICK  (P55024), TYRO_COTJA  (Q08410), TYRO_GORGO  (Q9BDE0), 
TYRO_HUMAN  (P14679), TYRO_MOUSE  (P11344), TYRO_ORYLA  (P55025), 
TYRO_PELNI  (Q04604), TYRO_PELSI  (P55026), TYRP1_AMBME (P55027), 
TYRP1_BOVIN (Q8WN57), TYRP1_CARAU (P55028), TYRP1_CHICK (O57405), 
TYRP1_HUMAN (P17643), TYRP1_MOUSE (P07147), TYRP2_BOVIN (Q95119), 
TYRP2_CHICK (O93505), TYRP2_HUMAN (P40126), TYRP2_MOUSE (P29812), 
TYRP2_PIG   (Q4R1H1), WDR59_CHICK (Q5ZLG9), WDR59_HUMAN (Q6PJI9), 
WDR59_MOUSE (Q8C0M0)
» More

PDB
[Detailed view]
9 PDB

1KLO; 1NPE; 1TLE; 2Y38; 4AQS; 4AQT; 4PLM; 4PLN; 4PLO

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