Entry: PS01248

General information about the entry

Entry name [info] EGF_LAM_1
Accession [info] PS01248
Entry type [info] PATTERN
Date [info] NOV-1997 (CREATED); NOV-1997 (DATA UPDATE); JUN-2016 (INFO UPDATE).
PROSITE Doc. [info] PDOC00961

Name and characterization of the entry

Description [info] Laminin-type EGF-like (LE) domain signature.
Pattern [info]
C-x(1,2)-C-x(5)-G-x(2)-C-x(2)-C-x(3,4)-[FYW]-x(3,15)-C.

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2016_08 which contains 551'987 sequence entries.


Total number of hits 564 in 132 different sequences
Number of true positive hits 524 in 92 different sequences
Number of 'unknown' hits 0
Number of false positive hits 40 in 40 different sequences
Number of false negative sequences 1
Number of 'partial' sequences 1
Precision (true positives / (true positives + false positives)) 92.91 %
Recall (true positives / (true positives + false negatives)) 99.81 %

Comments [info]

Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 21
Site [info] disulfide at position 1
Site [info] disulfide at position 3
Site [info] disulfide at position 7
Site [info] disulfide at position 9
Site [info] disulfide at position 13
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
92 sequences

AGRIN_CHICK (P31696    ), AGRIN_DIPOM (Q90404    ), AGRIN_HUMAN (O00468    ), 
AGRIN_MOUSE (A2ASQ1    ), AGRIN_RAT   (P25304    ), ATRN1_HUMAN (Q5VV63    ), 
ATRN1_MOUSE (Q6A051    ), ATRN_HUMAN  (O75882    ), ATRN_MOUSE  (Q9WU60    ), 
ATRN_RAT    (Q99J86    ), CELR1_HUMAN (Q9NYQ6    ), CELR1_MOUSE (O35161    ), 
CELR2_HUMAN (Q9HCU4    ), CELR2_MOUSE (Q9R0M0    ), CELR2_RAT   (Q9QYP2    ), 
CELR3_HUMAN (Q9NYQ7    ), CELR3_MOUSE (Q91ZI0    ), CELR3_RAT   (O88278    ), 
EPI1_CAEEL  (Q21313    ), LAM2_CAEEL  (Q18823    ), LAMA1_HUMAN (P25391    ), 
LAMA1_MOUSE (P19137    ), LAMA2_HUMAN (P24043    ), LAMA2_MOUSE (Q60675    ), 
LAMA3_HUMAN (Q16787    ), LAMA3_MOUSE (Q61789    ), LAMA4_HUMAN (Q16363    ), 
LAMA4_MOUSE (P97927    ), LAMA5_HUMAN (O15230    ), LAMA5_MOUSE (Q61001    ), 
LAMA_DROME  (Q00174    ), LAMB1_CHICK (Q01635    ), LAMB1_DROME (P11046    ), 
LAMB1_HUMAN (P07942    ), LAMB1_HYDVU (Q27262    ), LAMB1_MOUSE (P02469    ), 
LAMB2_HUMAN (P55268    ), LAMB2_MOUSE (Q61292    ), LAMB2_RAT   (P15800    ), 
LAMB3_HUMAN (Q13751    ), LAMB3_MOUSE (Q61087    ), LAMB4_DANRE (Q8JHV6    ), 
LAMB4_HUMAN (A4D0S4    ), LAMB_HIRME  (Q25092    ), LAMC1_DANRE (Q1LVF0    ), 
LAMC1_DROME (P15215    ), LAMC1_HUMAN (P11047    ), LAMC1_MOUSE (P02468    ), 
LAMC1_XENTR (A0JP86    ), LAMC2_HORSE (Q8HZI9    ), LAMC2_HUMAN (Q13753    ), 
LAMC2_MOUSE (Q61092    ), LAMC3_HUMAN (Q9Y6N6    ), LAMC3_MOUSE (Q9R0B6    ), 
MEGF8_HUMAN (Q7Z7M0    ), MEGF8_MOUSE (P60882    ), MEGF8_RAT   (Q9QYP0    ), 
MEGF9_HUMAN (Q9H1U4    ), MEGF9_MOUSE (Q8BH27    ), NET1_CHICK  (Q90922    ), 
NET1_HUMAN  (O95631    ), NET1_MOUSE  (O09118    ), NET1_PIG    (Q2HXW4    ), 
NET1_RAT    (Q924Z9    ), NET3_CHICK  (Q90923    ), NET3_HUMAN  (O00634    ), 
NET3_MOUSE  (Q9R1A3    ), NET4_HUMAN  (Q9HB63    ), NET4_MOUSE  (Q9JI33    ), 
NET4_PONAB  (Q5RB89    ), NET5_HUMAN  (Q8WTR8    ), NET5_MOUSE  (Q3UQ22    ), 
NETA_DROME  (Q24567    ), NETB_DROME  (Q24568    ), NTNG1_HUMAN (Q9Y2I2    ), 
NTNG1_MOUSE (Q8R4G0    ), NTNG2_HUMAN (Q96CW9    ), NTNG2_MOUSE (Q8R4F1    ), 
PGBM_HUMAN  (P98160    ), PGBM_MOUSE  (Q05793    ), STAB1_HUMAN (Q9NY15    ), 
STAB1_MOUSE (Q8R4Y4    ), STAB2_HUMAN (Q8WWQ8    ), STAB2_MOUSE (Q8R4U0    ), 
STAB2_RAT   (Q8CFM6    ), STAN_DROME  (Q9V5N8    ), TAG53_CAEEL (Q19981    ), 
UNC52_CAEEL (Q06561    ), UNC6_CAEEL  (P34710    ), USH2A_HUMAN (O75445    ), 
USH2A_MOUSE (Q2QI47    ), USH2A_RAT   (Q8K3K1    )
» more

UniProtKB/Swiss-Prot
False negative sequences
1 sequence

SIGK_DICDI  (Q6TMJ6    )

		
UniProtKB/Swiss-Prot
'Partial' sequences
1 sequence

LAMBV_CHICK (Q01636    )

		
UniProtKB/Swiss-Prot
False positive sequences
40 sequences

ADP1_YEAST  (P25371    ), CRE2A_XENLA (Q5XH36    ), CRE2B_XENLA (Q4V7M2    ), 
CREL1_BOVIN (Q5EA46    ), CREL1_HUMAN (Q96HD1    ), CREL1_MOUSE (Q91XD7    ), 
CREL1_RAT   (Q4V7F2    ), CREL2_BOVIN (Q2KIT5    ), CREL2_CRIGR (Q60438    ), 
CREL2_DANRE (Q7SXF6    ), CREL2_HUMAN (Q6UXH1    ), CREL2_MOUSE (Q9CYA0    ), 
CREL2_RAT   (Q4G063    ), POL_COYMV   (P19199    ), SRCH_HUMAN  (P23327    ), 
SRCH_RABIT  (P16230    ), TYRO_BOVIN  (Q8MIU0    ), TYRO_CANLF  (P54834    ), 
TYRO_CHICK  (P55024    ), TYRO_COTJA  (Q08410    ), TYRO_GORGO  (Q9BDE0    ), 
TYRO_HUMAN  (P14679    ), TYRO_MOUSE  (P11344    ), TYRO_ORYLA  (P55025    ), 
TYRO_PELNI  (Q04604    ), TYRO_PELSI  (P55026    ), TYRP1_AMBME (P55027    ), 
TYRP1_BOVIN (Q8WN57    ), TYRP1_CARAU (P55028    ), TYRP1_CHICK (O57405    ), 
TYRP1_HUMAN (P17643    ), TYRP1_MOUSE (P07147    ), TYRP2_BOVIN (Q95119    ), 
TYRP2_CHICK (O93505    ), TYRP2_HUMAN (P40126    ), TYRP2_MOUSE (P29812    ), 
TYRP2_PIG   (Q4R1H1    ), WDR59_CHICK (Q5ZLG9    ), WDR59_HUMAN (Q6PJI9    ), 
WDR59_MOUSE (Q8C0M0    )
» more

PDB
[Detailed view]
12 PDB

1KLO; 1NPE; 1TLE; 2Y38; 4AQS; 4AQT; 4OVE; 4PLM; 4PLN; 4PLO; 4URT; 4WNX

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