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PROSITE entry PS50221


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General information about the entry

Entry name [info] GAIN_B
Accession [info] PS50221
Entry type [info] MATRIX
Date [info] 01-DEC-2001 CREATED;
29-MAY-2024 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC50221
Associated ProRule [info] PRU00098

Name and characterization of the entry

Description [info] GAIN-B domain profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=159;
/DISJOINT: DEFINITION=PROTECT; N1=6; N2=154;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=1.9929707; R2=0.0094988; TEXT='-LogE';
/CUT_OFF: LEVEL=0; SCORE=1054; N_SCORE=12.0; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=475; N_SCORE=6.5; MODE=1; TEXT='?';
/DEFAULT: M0=-27; D=-150; I=-150; B1=-1000; E1=-1000; MI=-380; MD=-380; IM=-380; DM=-380;
...
                A    C    D    E    F    G    H    I    K    L    M    N    P    Q    R    S    T    V    W    Y
/I:         B1=0; BI=-380; BD=-380;
/M: SY='P';  M= -64, -83,  -9,  23,  -1, -70,  23, -75, -11, -74,  -3, -12,  72,  38,   6,   9,  -4, -75,  13, -16;
/M: SY='Y';  M=  -8, -74, -65, -25,  15, -70,  -5,  15, -35, -42,  14,  15,   0,   4,  18,  27,  15,  -3, -71,  28;
/M: SY='L';  M= -35,  27, -69,   6,  29, -76, -68, -13, -65,  38,   2,  -5, -76, -65, -10,  17,  23,   6, -76, -57;
/M: SY='Q';  M= -18, -73,   4,  -5,  -8, -68,  22, -30, -29, -65,  -7,  13, -70,  41, -20,  31,  36,   9, -77,  19;
/M: SY='L';  M= -19, -73, -81, -75,  25, -82, -75,  44, -75,  46,  -9, -75,  -2, -27, -76, -33,  19,  13, -74, -55;
/M: SY='S';  M=  17, -72, -25, -12, -74,   8,  24,   3,  -7, -45, -15, -26,  -6, -17, -64,  59,  -1, -23, -83, -67;
/M: SY='S';  M=  21, -73, -62,  -9, -21, -63, -64, -37, -11, -47, -64,   2,  25,  31, -10,  49,  17, -17,  22, -25;
/M: SY='E';  M= -23, -10,  -3,  36, -78,   1,  23, -38,  28, -77, -69,  15,  25,  20,  -5,  18, -11, -74, -81, -14;
/I:         I=-36; MI=0; MD=-90; IM=0; DM=-90;
/M: SY='N';  M=   5, -73,   8, -27, -75, -36,  -4, -69, -32, -73,  16,  73, -19,  10,   5,  23,   7, -16,  17, -68;
/M: SY='V';  M=  -7, -73, -79, -72,   0, -81, -71,  35, -71,  37, -43, -74, -79,  22, -38, -66,   8,  39, -71,  23;
/M: SY='Q';  M=  19, -14, -23,   6,  -7, -65, -63, -62, -26,  -9, -61,  12, -21,  37, -30,  36,  29,  -1, -81, -65;
/M: SY='M';  M= -28, -74, -77,  -5, -19, -81, -71,  27, -41,  41,  63, -75,  15, -67, -34, -17, -60,  28, -77, -60;
/M: SY='S';  M= -56, -73, -51,  39, -79, -19, -58, -76,  21, -43, -69,  37, -66,  34, -23,  55,  23, -71, -83, -70;
/M: SY='V';  M= -30,   3, -30, -73, -57, -18, -73,  21, -72,  17,  24, -20, -77, -70, -75,  24, -25,  58, -82, -16;
/M: SY='P';  M=  -6, -16, -60,  12,   9, -67,  -1, -34, -24, -66,  32,  14,  37,  36, -31,  26,  27, -65,   4,  -9;
/M: SY='H';  M=  12, -74,  -5,  15, -18,  -5,  35, -14,   8, -29, -61,  20,  -6, -57, -26,   8,   9,  12, -83, -65;
/M: SY='L';  M= -36, -74, -68, -13,  12, -41,  -5,  16,  -1,  36,  -6,  20, -35,   9, -65,   3,  -7,   1, -74, -13;
/M: SY='E';  M= -20, -76,   4,  39, -21, -39,   5, -39,  17, -27,  -3,  -4,  21, -10,  -6,  31,  12, -39, -82, -66;
/M: SY='P';  M=   6,  -9,  23, -19, -26, -33,  -5, -70, -14, -12, -65,  26,  45, -14, -10,  11,  34, -67, -82, -20;
/M: SY='T';  M=  18, -73,  -4, -13, -73,  -8,  -2, -11,  25, -68, -14,   6, -69,  -9,  -4,  25,  26,   3,  26, -66;
/M: SY='N';  M=   9,  -5, -24,   6, -72,  10,  14, -38, -30, -14, -62,  43, -16, -11, -65,  15,  26,  10, -86, -69;
/I:         I=-12; MI=0; MD=-30; IM=0; DM=-30;
/M: SY='N';  M= -24,-101, -82,  -7,-100, -29,  14, -55, -83, -99, -92,  33, -99, -83, -17, -42,   4, -28,-112, -33; D=-12;
/I:         I=-12; DM=-30;
/M: SY='H';  M= -27, -97,  -9, -78, -89, -45,  18, -12, -36, -26, -78,  10,  -5,  12, -14, -32, -33, -17,  15, -83; D=-12;
/I:         I=-12; DM=-30;
/M: SY='Q';  M=  15, -89, -41, -77,  -1, -20, -79, -46, -74, -82, -78,   8,  -3,  15,  -8,  13, -71,  -3, -91, -19; D=-12;
/I:         I=-12; DM=-30;
/M: SY='G';  M= -26, -85, -73,  -3, -74,  21, -72, -44, -67,  20,  -9, -17, -31,  20,  14,  -8, -10, -42, -85, -19; D=-12;
/I:         I=-12; DM=-30;
/M: SY='D';  M=  27, -79,  32, -62, -40,  -5, -12, -76, -66, -30, -72,  23,  30, -17, -34,  23, -25, -39, -88, -30; D=-12;
/I:         I=-12; DM=-30;
/M: SY='S';  M= -27, -78, -66, -62, -71, -19,   2, -71,  -9, -75, -68,  -3, -14,  14,  41,  44,  18,  -5,  20,  19; D=-12;
/I:         I=-12; DM=-30;
/M: SY='M';  M= -36, -74, -16, -75,  17, -82, -73,  56, -70, -23,  76, -72, -76, -70,  -7, -31,  -9,  42, -77, -56;
/M: SY='Q';  M= -12, -75,   3,  21, -17, -72, -62, -28,  -4, -20, -10,   0, -72,  38,  27,   5,   0,  28, -79, -16;
/M: SY='L';  M= -67, -75, -81, -74,  27, -85, -12,  43, -74,  56, -40, -76, -25,  23, -74, -35, -16,   5, -72, -53;
/M: SY='P';  M= -30, -87,  -9, -56, -86, -20,  -8, -77, -33, -84, -72, -24, 109, -13, -32,  -4, -27, -79, -83, -80;
/M: SY='W';  M= -10,  35, -65,   3, -69, -38,  22, -69,  10, -47, -65, -13,  40,  13,  20,  -6,  -5,  -4,  81, -14;
/M: SY='T';  M=  22, -73,  26,   2,  -2,   0,  -5, -72,  -4, -46,   1,  -2, -22, -14,   7,  23,  33, -67, -81, -65;
/I:         I=-20; MD=-51;
/M: SY='L';  M=  -1, -76,  -8, -13, -20, -40,   4,   4, -28,  37, -14, -68,  -2,  -2, -38,  11, -33,  11, -81, -63; D=-20;
/I:         I=-20; MD=-51;
/M: SY='F';  M= -11, -76, -81, -78,  47, -27,  -8,  20, -44,  38, -14,  -2, -83, -75, -32, -70, -10,  11, -73, -53; D=-20;
/I:         I=-20; MD=-51;
/M: SY='W';  M=  -1, -84, -25,  20,  -7, -17, -12, -19,  -3, -49, -70, -69, -79,  -5, -24,  23, -34,  10,  45, -69; D=-20;
/I:         I=-20; MI=0; MD=-51; IM=0; DM=-51;
/M: SY='P';  M= -47, -88, -11, -12,   1, -19,  -1, -39,  18, -27,  -6, -28,  28,  15,  -9,  13, -68, -45, -84, -19; D=-20;
/I:         I=-20; DM=-51;
/M: SY='P';  M=  18, -81, -65,  10, -80, -10, -18, -33, -36, -11, -67,  30,  39,   7, -31, -11, -11, -17, -88, -76; D=-20;
/I:         I=-20; DM=-51;
/M: SY='S';  M= -16, -79,  16, -11, -80,  -9, -16, -39, -32, -34, -70,  17,  40, -27, -38,  41,   1,  -3, -90, -75; D=-20;
/I:         I=-20; DM=-51;
/M: SY='H';  M= -31, -79,  22,  31, -76, -69,  37, -72, -22,  -8, -64,  37,  32,  11,  33,   2, -13, -39, -86, -67;
/M: SY='S';  M=  10, -73, -23,  -8, -28, -19, -62, -72,   4, -75, -68,  15,  23,  18,  -1,  57,   8, -23, -82, -69;
/M: SY='G';  M=   4, -76,  25, -39, -75,  63, -66, -73, -65, -16,  -1,  -4,   4,   2, -71,  10, -24, -38, -79, -20;
/I:         I=-38; MI=0; MD=-97; IM=0; DM=-97;
/M: SY='D';  M=   6,  24,  31,  24, -68, -17,  27, -30, -62,  -2, -61,  -5,  27, -60, -29,  -8, -60,  16,  18, -16;
/M: SY='S';  M= -20,  27, -68, -16,  23, -72,   1, -54,  -2,  -1, -56, -62, -18, -18, -27,  33,  30,  23, -72,  24;
/M: SY='R';  M= -10, -75, -30, -57, -70, -12,  -7, -30,  28, -22, -59, -58, -72,  31,  45,   4,  24,  21, -79, -16;
/M: SY='V';  M=  15, -72, -79, -73, -56, -79, -76,  49, -73,  31, -43, -16, -26,   7, -75, -65, -25,  49, -80, -63;
/M: SY='Q';  M=  -2, -75, -69, -67,  -4,  15,  22,  38, -66, -11, -53,  23, -74,  38, -69, -31,   9,  20,  17, -60;
/M: SY='F';  M= -24, -10, -75, -15,  74, -40,  -1,  -9, -70,  10, -52, -18, -80, -71, -27,  -5, -26,  12, -59,  39;
/M: SY='T';  M= -39, -72, -75, -73, -13, -78, -72,  28, -71,  38,  28,  -9, -14, -69, -74,   1,  40,  22,  25, -24;
/M: SY='W';  M=  29, -15, -12,  -9,  16, -68, -70, -10, -24,   3, -57, -64, -73, -62, -23,  35,  -7,   9,  66, -18;
/M: SY='Y';  M= -71, -77, -22, -76,  81, -38, -58, -11, -73,  -5, -53, -18, -26, -73, -72, -18, -13, -57, -46,  81;
/M: SY='P';  M= -21, -79,  19,  15, -34,  -7,  36, -77,  -6, -54, -68,  38,  41,   6,  29,   9, -22, -43, -84, -67;
/M: SY='N';  M=   4, -70, -54, -22, -77,  -5,   1, -74, -10, -77, -69,  61, -26, -15, -13,  45,  49, -68, -87, -70;
/I:         I=-45; MD=-115;
/M: SY='M';  M= -42, -77, -76, -13,  -1, -21,   1,  16, -68,  43,  45, -72, -38,  15,  -3, -69,   2, -10, -78, -59; D=-45;
/I:         I=-45; MI=-115; IM=-115; DM=-115;
/M: SY='G';  M= -15, -77,  -8,   3, -70,  57,  32, -68, -62, -40, -65,   3, -72,  21, -26, -27, -10,   9,  17,  14;
/M: SY='W';  M=   0, -75,  12, -63, -17, -21,  -7, -56,   2,  40,  -5,   5, -34,   4, -23, -13, -28, -32,  48,  22;
/M: SY='F';  M= -67, -75, -81, -75,  66, -42, -70,  40, -72,  39, -44, -74, -81,  17, -31,  -8, -22, -21, -63,  -8;
/I:         I=-10; MD=-24;
/M: SY='L';  M= -35, -79, -79, -27,   5, -85,  -1,  -8,  -2,  58,  -7, -77, -28,  13,  -2, -74, -68, -27, -74,  -6; D=-10;
/I:         I=-10; MD=-24;
/M: SY='P';  M= -12, -89,   5,   7, -92, -19, -74, -33,   0, -89, -80,  11,  67, -67, -73,   5,  -9, -81, -94, -86; D=-10;
/I:         I=-10; MD=-24;
/M: SY='P';  M= -11, -88, -70,   2, -26, -48,  17, -76, -34, -46, -74,  12,  69, -16, -76, -19,   3, -12, -92, -79; D=-10;
/I:         I=-10; MD=-24;
/M: SY='S';  M=  11, -84, -70,  15, -88,  -2, -77, -39, -33, -56, -78,  -4, -80, -19, -27,  28,  26, -40, -95, -83; D=-10;
/I:         I=-10; MD=-24;
/M: SY='P';  M= -21, -94,   2, -80,  30, -17, -78, -39, -83, -22, -76,  -7,  36, -22, -87, -15, -77, -80, -79,  31; D=-10;
/I:         I=-10; MD=-24;
/M: SY='N';  M= -52, -92,   4, -78,   7, -88, -77, -75, -80,   8, -72,  24,  19,   1, -85, -30,   2, -46, -88,  13; D=-10;
/I:         I=-10; MD=-24;
/M: SY='S';  M= -24, -94, -27, -13, -11, -46, -17, -86, -76, -26, -82,  -3,  -2,   7,  -6,   9,  -1, -47, -99, -83; D=-10;
/I:         I=-10; MI=0; MD=-24; IM=0; DM=-24;
/M: SY='W';  M=   3, -98,  -9,   4, -97,  -4,  -4, -94,  -8, -50, -88, -15, -91, -27,  -7, -18, -81, -40,  13, -88; D=-10;
/I:         I=-10; DM=-24;
/M: SY='Q';  M= -23, -95, -17,  -3, -88,  -9, -78, -14, -37, -36, -13,  -9,  17,  22, -19,   4, -75, -81, -94, -15; D=-10;
/I:         I=-10; DM=-24;
/M: SY='D';  M= -18, -89,  33, -16, -83, -39, -14, -20, -67, -20, -74,  23, -35,  22,   6, -31, -13, -32, -95, -19; D=-10;
/I:         I=-10; DM=-24;
/M: SY='P';  M= -20, -88, -10, -36, -85,   1, -10, -38,   3, -29, -75,  11,  39,  11, -71,   4,  -4, -44,  16, -79; D=-10;
/I:         I=-10; DM=-24;
/M: SY='N';  M= -16, -85, -64, -18,  -9,   5, -68, -85,   1, -86, -78,  53,  11,   1,  14,  17, -65, -48, -89, -77; D=-10;
/I:         I=-10; DM=-24;
/M: SY='E';  M= -44,  -4, -11,  28, -83,  -1, -69, -75,  13, -31, -72,  19, -24,   0,  16, -39,  14,  -6, -91, -78; D=-10;
/I:         I=-10; DM=-24;
/M: SY='N';  M= -69, -85, -26,   1, -78, -44,  18, -80,  -2, -18, -71,  39,  14,  21,  20,  19, -20, -80, -86,   5; D=-10;
/I:         I=-10; DM=-24;
/M: SY='R';  M= -46, -82, -70, -18, -71, -78, -67, -28, -11,  16,  -8,  19,  13,   5,  33,   7,   5, -23, -85, -18; D=-10;
/I:         I=-10; DM=-24;
/M: SY='T';  M= -19,  30, -75, -34,  -1,   1, -76, -16, -17, -32, -63, -68,  -2, -30, -10,  -1,  36,  27, -83, -19; D=-10;
/I:         I=-10; DM=-24;
/M: SY='V';  M= -19, -75, -82, -78, -22, -83, -75,  12, -29,  42,  22, -12, -83, -73, -76,  -8, -27,  43, -81, -17; D=-10;
/I:         I=-10; DM=-24;
/M: SY='N';  M=  15, -71,   2, -10, -70, -21, -58, -24, -26, -27,  -8,  75, -23, -57, -64,  11,  17,  -4, -84,  -8; D=-10;
/I:         I=-10; DM=-24;
/M: SY='S';  M=   1, -67, -21,  11, -76,  13, -61, -74, -57, -77, -70,  16, -65, -52, -64,  80,  36, -67, -84, -70;
/M: SY='P';  M= -63, -80,  12, -53, -63, -16, -13, -26,  16,  -5, -59, -18,  49,  44,  36,   0, -26, -68, -69,  43;
/M: SY='V';  M= -57, -70, -83, -77, -54, -47, -80,  37, -71, -12,  -1, -77, -79, -74,  -2, -68, -55,  86, -82, -15;
/M: SY='I';  M= -62, -74, -79, -77, -18,   0, -72,  59, -70,  12,  47, -23, -15, -70,  -9, -68, -59,  45, -73,   7;
/M: SY='S';  M=   3, -70, -63, -65, -20,  21,   3, -11, -61, -66, -12,  -6, -70, -57, -22,  69,  -3, -19, -69,  47;
/M: SY='A';  M=  40,  -3, -74, -69, -59,  -5, -71,  -2, -68,  25,  -3, -68,   9, -67, -31, -20,   6,  35, -76,  -2;
/M: SY='S';  M=  19, -70, -60,   9,  -6,   4, -64, -12, -23, -68, -64, -54, -67,   2,   8,  63,  18, -10, -78, -64;
/M: SY='V';  M= -61,   8, -82, -76, -51, -84, -77,  54, -75,  44,  -2, -76, -79,  -6, -76, -28, -23,  54, -79, -59;
/M: SY='S';  M= -58, -74,  -4,  -7, -23,  17,  -8, -37, -25,   3, -60,  17,   0,   7,  11,  37,  16, -36, -73,  27;
/I:         I=-18; MD=-45;
/M: SY='N';  M= -17, -78,  23,   5, -82,  25,  33, -82,  -2, -82, -72,  59,  32,  10,  -2,   8, -58, -79, -86, -71; D=-18;
/I:         I=-18; MI=0; MD=-45; IM=0; DM=-45;
/M: SY='P';  M= -32,  26,  18, -12,   9, -45, -71, -37, -15, -49,   7, -24,  46,  -5,   1,  14,   2, -74, -86, -71; D=-18;
/I:         I=-18; DM=-45;
/M: SY='W';  M= -64, -81, -69, -36, -75,  16,  -7, -26, -14, -17, -65,  -1,  26,  31,   0,  -1,  28,  -1,  34, -70; D=-18;
/I:         I=-18; DM=-45;
/M: SY='T';  M= -36, -77, -65, -12, -72, -74, -13,   5,   3, -21,  -2,  17,   8,   5,   6,  18,  35,  12, -87, -69; D=-18;
/I:         I=-18; DM=-45;
/M: SY='R';  M=  -4, -80, -66,   3, -14,  14, -68, -38,  14, -10, -63, -27,  10,  18,  31, -31,   4,  -8,  23, -67; D=-18;
/I:         I=-18; DM=-45;
/M: SY='N';  M=  -3, -75,  17,   6,  -8, -35,  23, -69, -11, -40, -65,  62,  11, -21, -62,   1,   8, -23, -78,  28; D=-18;
/I:         I=-18; DM=-45;
/M: SY='L';  M= -36, -72, -70,  -4, -15, -20, -66, -45, -65,  64, -42, -20,   7,   7, -17, -19,  17, -14, -75, -59;
/M: SY='S';  M=  22, -69,  26,  -7, -71, -34,  -5, -39, -28,   3, -15,  15, -68,  16, -62,  54,  14, -33, -83, -66;
/M: SY='D';  M= -34, -76,  50,  28, -79, -30, -15, -72,  28, -74,  -7,  26,   1,  16,   7,  25, -24, -10, -85, -68;
/M: SY='P';  M= -13, -81, -18,  12, -36, -34, -64, -72, -36, -29, -67,  28,  98, -10, -67,   6, -22, -73, -81, -75;
/M: SY='V';  M= -32, -72, -83, -77, -17, -84, -77,  57, -75, -16,  31, -77, -78, -20, -76, -69, -56,  74, -75,  16;
/M: SY='T';  M= -33, -71, -12,   0, -31, -71,   3,  33, -28,  -4, -54,  28, -69, -16,   2,  -7,  61, -33, -77,  13;
/M: SY='Y';  M= -65, -73, -83, -79,  47, -85, -67,  36, -76,  36,   0, -79, -82, -74, -75, -72, -61,  46, -59,  59;
/M: SY='T';  M= -23, -71, -21,  21, -36, -36,  23,  -3,  -8, -67, -62,  10, -65,  25,  -2,  33,  62, -32, -83, -64;
/M: SY='F';  M= -68, -72, -86, -80,  71, -85, -69,  15, -78,  55,  21, -80, -84, -77, -76, -75, -63,  20, -59,  13;
/I:         I=-13; MD=-32;
/M: SY='Q';  M= -14, -79,  -3,   8, -31, -70, -61, -75,  26, -74, -68, -56, -71,  42,  41,  28,  20, -38,  40,   6; D=-13;
/I:         I=-13; MD=-32;
/M: SY='H';  M= -38, -85, -27, -65,  -3, -78, 112, -11,  -4, -17, -61, -27, -79, -60, -22,   5, -69, -74, -90, -11; D=-13;
/I:         I=-13; MD=-32;
/M: SY='H';  M= -37, -82, -30,  -8, -19, -84,  57,  32, -16,  14,  -5, -29, -79, -29, -26, -69,  19,  -5,  20, -61; D=-13;
/I:         I=-13; MD=-32;
/M: SY='Q';  M=  -8, -83, -62,  36,   2, -77, -66, -37,   8, -25, -69,   9, -34,  39,  15,   1, -14, -40, -84, -70; D=-13;
/I:         I=-13; MD=-32;
/M: SY='P';  M= -26, -84,  -1,  -6, -83, -18,   1, -77, -12, -55, -12,  11,  40,  30, -22,   4,  26, -39, -89, -25; D=-13;
/I:         I=-13; MD=-32;
/M: SY='W';  M= -41, -91,  11,  -2, -87, -81, -79, -20,  -6, -55, -80, -70,  -8,  16, -28,  36, -13, -39,  53, -78; D=-13;
/I:         I=-13; MI=0; MD=-32; IM=0; DM=-32;
/M: SY='N';  M= -11, -85, -17,  -2, -89,  32,  20, -38,  18, -87, -77,  35,  33, -17, -66,  -3, -66, -82, -90, -79; D=-13;
/I:         I=-13; DM=-32;
/M: SY='R';  M= -25, -75, -15, -30, -16,  15, -14, -60, -15,  -4,  17,  10,   2, -57,  48,  -8,  22,   3,  29, -15; D=-13;
/I:         I=-13; DM=-32;
/M: SY='H';  M=  -8, -74,  -1,  -3,  -8, -17,  53, -30,  -6, -21, -58, -55, -27,  35, -26,  28,  24,  -2, -74,  26; D=-13;
/I:         I=-13; DM=-32;
/M: SY='W';  M= -61, -75,  24,  22, -25, -67,  -4, -34,  26, -44, -64,  38, -67,  17,  -6,  10,  41, -36,  53,  -5; D=-13;
/I:         I=-13; DM=-32;
/M: SY='P';  M=   2, -74, -68, -62, -67, -68,  17,  -5, -20,  13, -55, -63,  74, -62, -68,  35,  17,   9, -81, -67; D=-13;
/I:         I=-13; DM=-32;
/M: SY='Q';  M= -63, -76, -66, -21,  -4, -11,  42,  28,   0,  20,   0, -28, -73,  52,  -6, -34,   1,  -8, -71,  20; D=-13;
/I:         I=-13; DM=-32;
/M: SY='C';  M= -15, 149, -81, -80, -73, -76, -81, -78, -77, -70, -70, -68, -22, -83, -83, -63, -62, -66,-100, -83; D=-13;
/I:         I=-13; DM=-32;
/M: SY='V';  M=  41, -67, -75, -68, -17, -70, -70, -34, -68,  12, -46, -28, -75,  11, -69, -34, -53,  72, -74,  16;
/M: SY='F';  M= -68, -74, -77, -73,  96, -41,  17, -55, -67,  -9, -52, -68, -80, -20,  -4,  13, -63, -59,  46,  55;
/M: SY='W';  M= -75, -96, -99, -79,  24, -75, -93, -69, -72, -41, -69, -92, -20, -73, -75, -80, -83, -81, 171,  10;
/M: SY='N';  M= -62, -75,  75,  26, -81, -60,  -3, -79,  11, -80, -73,  77, -17,   0, -54,  -3, -53, -49, -92, -69;
/M: SY='H';  M= -34, -76,  -3,  35,  36, -19,  53, -67,  12, -20,  -6, -55,   1,  23, -23,  18, -21, -67, -65,  38;
/M: SY='S';  M=   5, -72,  34,   0, -27, -37,  18, -40, -18, -44, -19,   9,   4,  13,  21,  49,  12, -66, -79, -15;
/M: SY='E';  M=   5, -73,  -2,  31, -72,   6, -15, -34,   1, -13,   1,   2,  16,  30, -12,  19,   7,  -6, -79, -66;
/I:         I=-29; MD=-75;
/M: SY='Q';  M=  -3, -98,  -1, -16, -34, -21, -84, -95, -80, -34, -88,   6,  -2,  16, -43,   7, -79, -93,-104, -91; D=-29;
/I:         I=-29; MI=0; MD=-75; IM=0; DM=-75;
/M: SY='H';  M= -85, -12, -28, -38, -33,  -1,  19, -93, -85, -26,  -6,  -8, -97,   4, -49,  -4,  -4, -93,   7, -85; D=-29;
/I:         I=-29; DM=-75;
/M: SY='G';  M= -54, -77, -13, -12, -77,  84, -13, -80, -28, -37,  24, -18, -69, -21, -29,  -2, -65, -77,  22, -71; D=-29;
/I:         I=-29; DM=-75;
/M: SY='H';  M=  -7, -74,  -5, -31, -69,  39,  47, -32, -19, -39,  21, -53, -69,  27,  -5,  23,  17,  -7, -77,   4; D=-29;
/I:         I=-29; DM=-75;
/M: SY='W';  M= -74, -15,-100, -80,  -3, -73, -99, -72, -72, -70, -73, -92, -79, -72, -75, -35, -84, -85, 175, -28;
/M: SY='S';  M=  -2, -69,  51, -49, -76, -57, -57, -72,   5, -45, -68,  35, -66,  -8,   2,  64,  31, -67, -85, -67;
/M: SY='T';  M=   5, -67,   5, -25, -72, -60, -62, -66, -54, -22, -63, -15,  24,  -8,   5,  60,  64, -61, -83, -67;
/M: SY='E';  M= -40, -76,  56,  59, -78, -66,  -3, -77, -27, -34, -68,   4, -64,  29,  27,  31,  -5, -72, -84, -67;
/M: SY='G';  M= -30, -77, -25, -72, -26,  97, -69, -87, -66, -83, -74, -16, -21, -66, -23, -50, -67, -82, -74, -74;
/I:         I=-42; MI=0; MD=-106; IM=0; DM=-106;
/M: SY='C';  M= -28, 147, -81, -80, -17, -76, -79, -29, -76, -35,   7, -68, -89, -82, -82, -64, -61, -61, -94, -75;
/M: SY='Q';  M= -12, -74, -56,  25, -26, -67, -13, -28,  30, -36, -59, -54, -67,  47,  36,  36,   2, -14, -70,  27;
/M: SY='V';  M= -15, -70, -75, -69, -54, -77,  17,   1, -68,  44,  21, -70,  37, -67, -25, -62,  26,  49, -79, -59;
/I:         I=-20; MD=-51;
/M: SY='V';  M= -30, -72, -66,  18, -62,   0,  18,  22, -18,  10,  -3, -64, -71,  13, -25,  -7,   6,  47, -81, -62; D=-20;
/I:         I=-20; MD=-51;
/M: SY='H';  M=  -9, -79,  16,  49, -29, -14,  64, -38, -23, -49, -64, -26,  36,   4,  -3,   5, -20, -71, -77,  17; D=-20;
/I:         I=-20; MD=-51;
/M: SY='S';  M= -14, -73,  19,  24, -74,  19, -11, -68, -15, -11, -64, -12,  -3,  -9,  12,  41,  17, -16, -82, -68; D=-20;
/I:         I=-20; MD=-51;
/M: SY='N';  M= -61, -74,  38, -55, -76, -36, -56, -14, -28, -76, -69,  75, -71,  27, -36,  28,  35, -70, -88, -13; D=-20;
/I:         I=-20; MI=0; MD=-51; IM=0; DM=-51;
/M: SY='P';  M=  21, -73,  24,  -7, -71,  -1, -61, -13,  -4,  -8,  20,  32,  46,   1, -31,  -4,   0, -29, -80, -68;
/M: SY='S';  M= -30, -68,  21, -19, -73,  -3,   0, -36, -53, -45, -65,  44, -65,  -1,  -3,  62,  49, -65, -85, -66;
/M: SY='H';  M= -31, -75, -60, -14,   9, -70,  86,  -2,  -5, -38, -10, -17, -70,  46,  -7,   8,  17, -31, -67,  50;
/M: SY='T';  M=  17, -63, -64, -64, -65, -34, -71, -46, -62, -34, -55, -55, -65, -63, -68,  20,  84,  46, -85, -65;
/M: SY='T';  M= -10, -69, -59,  -7, -22, -67,  15,  15,   3, -39,  -7,  34, -69,  16,  -6,  22,  36,  34, -81, -61;
/M: SY='C';  M= -61, 150, -81, -81, -69, -77, -80, -72, -77, -22, -65, -68, -91, -84, -83, -64, -61, -30, -99, -79;
/M: SY='S';  M=  -7, -73, -29, -19, -19, -67,  18, -12,  -8,  23, -53, -20, -71,  42,  44,  45, -32, -59, -74, -11;
/M: SY='C';  M= -61, 147, -78, -78, -66, -76, -76, -75, -74, -67, -67, -65, -87, -80, -80, -61,  16, -64, -90,  15;
/M: SY='N';  M= -58, -71,  32, -51,  -6, -59,  44, -74, -49, -74, -66,  77, -69,  32,  13,  39,  26, -72, -86, -61;
/I:         I=-38; MI=0; MD=-97; IM=0; DM=-97;
/M: SY='H';  M= -38, -80, -56, -54, -26, -71, 138, -80, -53, -67, -55, -46, -71, -48,  31, -25, -65, -38, -95, -40;
/M: SY='L';  M= -65, -69, -83, -76,   3, -83, -68,   2, -76,  81,  38, -79, -81, -70, -74, -32, -27, -20, -70, -52;
/M: SY='T';  M=  -8, -63, -57, -60, -71,   1, -65, -65, -23, -69, -63, -10, -61, -58, -63,  50,  93, -57, -85, -67;
/M: SY='S';  M=  17, -68, -58, -61,  10, -34,  59, -31, -60, -64,   8,  41, -15, -55, -63,  61,   6, -10, -77,  -1;
/M: SY='F';  M= -74, -72, -85, -82, 113, -82, -63, -48, -77, -10, -49, -77, -85, -84, -74, -73, -66, -27, -40,  50;
/I:         I=-36; MI=0; MD=-90; IM=0; DM=-90;
/M: SY='A';  M=  75, -65, -64, -28,  10,  11, -67, -36, -25, -67, -63, -57, -66, -58, -65,  41, -15, -57, -73, -64;
/M: SY='I';  M= -59, -71, -84, -80, -50, -87, -82,  72, -77,  19,  10, -78, -77, -75, -78, -71, -55,  69, -79, -58;
/M: SY='L';  M= -66, -70, -80, -34,  24, -30, -68,  -1, -75,  78, -33, -79, -82, -16, -73, -73, -63,   0, -67,  -8;
/M: SY='M';  M=   6, -70, -77, -67, -56, -72, -59, -39, -63,  -5, 121, -69,  14,  11, -20, -31, -57,  23, -76, -56;
/M: SY='D';  M=  26, -75,  54,  -2, -15, -62, -58, -72, -51, -44, -66,  -9,  38,  46,  21,  30, -54, -44, -80, -66;
/M: SY='P';  M= -18, -73, -17, -58, -64, -68,  28,   3, -23,  24,  -7,  29,  49,  31, -63,  17,  -4,  10, -80, -62;
/M: SY='S';  M=  -3, -76,  -3, -61, -33, -31,  -5,   1, -29, -36, -62,  17,  43,  -7, -15,  45, -11, -19, -74,  33;
/M: SY='H';  M= -36, -83,  26,   5, -82, -15,  48, -80,  -5, -48, -21, -16,  17,  -9,  41,  10,   0, -49, -90, -70;
/M: SY='V';  M=  -5, -80,   5,   2,  -1, -77, -14,  -8, -27, -11, -63, -67,  10,  -3, -11,  19, -10,  22, -86, -68;
/M: SY='E';  M= -23, -83,  13,  37, -80, -34, -13, -26, -61, -29, -70, -16,  26,  21, -23,  27,  -5, -30, -88, -28;
/I:         E1=0; IE=-380; DE=-380;
» more

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2024_05 which contains 572'214 sequence entries.


Total number of hits 116 in 116 different sequences
Number of true positive hits 116 in 116 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 0
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 100.00 %

Comments [info]

Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 1
Matrix type [info] protein_domain
Scaling database [info] reversed
Author [info] CJA_Sigrist
Feature key [info] DOMAIN
Feature description [info] GAIN-B
Version [info] 6

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
116 sequences

AGRA2_DANRE (E7FBY6), AGRA2_HUMAN (Q96PE1), AGRA2_MOUSE (Q91ZV8), 
AGRA3_DANRE (S4X0Q8), AGRA3_HUMAN (Q8IWK6), AGRA3_MOUSE (Q7TT36), 
AGRB1_HUMAN (O14514), AGRB1_MOUSE (Q3UHD1), AGRB1_RAT   (C0HL12), 
AGRB2_HUMAN (O60241), AGRB2_MOUSE (Q8CGM1), AGRB2_PONAB (Q5R7Y0), 
AGRB3_HUMAN (O60242), AGRB3_MOUSE (Q80ZF8), AGRD1_BOVIN (A6QLU6), 
AGRD1_HUMAN (Q6QNK2), AGRD1_MOUSE (Q80T32), AGRD2_HUMAN (Q7Z7M1), 
AGRE1_HUMAN (Q14246), AGRE1_MOUSE (Q61549), AGRE1_RAT   (Q5Y4N8), 
AGRE2_CANLF (Q2Q421), AGRE2_HUMAN (Q9UHX3), AGRE2_MACMU (Q2Q426), 
AGRE3_HUMAN (Q9BY15), AGRE4_HUMAN (Q86SQ3), AGRE4_MOUSE (Q91ZE5), 
AGRE5_BOVIN (Q8SQA4), AGRE5_HUMAN (P48960), AGRE5_MOUSE (Q9Z0M6), 
AGRF1_HUMAN (Q5T601), AGRF1_MOUSE (Q8VEC3), AGRF2_HUMAN (Q8IZF7), 
AGRF2_MOUSE (E9Q4J9), AGRF2_RAT   (D4A3T6), AGRF3_HUMAN (Q8IZF5), 
AGRF3_MOUSE (Q58Y75), AGRF4_HUMAN (Q8IZF3), AGRF4_MOUSE (Q9D2L6), 
AGRF5_HUMAN (Q8IZF2), AGRF5_MOUSE (G5E8Q8), AGRF5_RAT   (Q9WVT0), 
AGRG1_GORGO (Q50DM6), AGRG1_HUMAN (Q9Y653), AGRG1_MACMU (Q50DM8), 
AGRG1_MOUSE (Q8K209), AGRG1_PANTR (Q50DM7), AGRG1_PONPY (Q50DM5), 
AGRG1_RAT   (Q8K3V3), AGRG2_HUMAN (Q8IZP9), AGRG2_MOUSE (Q8CJ12), 
AGRG2_RAT   (Q8CJ11), AGRG3_HUMAN (Q86Y34), AGRG3_MOUSE (Q8R0T6), 
AGRG4_HUMAN (Q8IZF6), AGRG4_MOUSE (B7ZCC9), AGRG5_HUMAN (Q8IZF4), 
AGRG5_MOUSE (Q3V3Z3), AGRG6_DANRE (C6KFA3), AGRG6_HUMAN (Q86SQ4), 
AGRG6_MOUSE (Q6F3F9), AGRG7_HUMAN (Q96K78), AGRG7_MOUSE (Q8BM96), 
AGRL1_BOVIN (O97831), AGRL1_HUMAN (O94910), AGRL1_MOUSE (Q80TR1), 
AGRL1_RAT   (O88917), AGRL2_BOVIN (O97817), AGRL2_HUMAN (O95490), 
AGRL2_MOUSE (Q8JZZ7), AGRL2_RAT   (O88923), AGRL3_BOVIN (O97827), 
AGRL3_HUMAN (Q9HAR2), AGRL3_MOUSE (Q80TS3), AGRL3_RAT   (Q9Z173), 
AGRL4_DANRE (Q7SY09), AGRL4_HUMAN (Q9HBW9), AGRL4_MOUSE (Q923X1), 
AGRL4_RAT   (Q9ESC1), AGRV1_DANRE (Q6JAN0), AGRV1_HUMAN (Q8WXG9), 
AGRV1_MOUSE (Q8VHN7), CELR1_HUMAN (Q9NYQ6), CELR1_MOUSE (O35161), 
CELR2_HUMAN (Q9HCU4), CELR2_MOUSE (Q9R0M0), CELR2_RAT   (Q9QYP2), 
CELR3_HUMAN (Q9NYQ7), CELR3_MOUSE (Q91ZI0), CELR3_RAT   (O88278), 
CELR_CAEEL  (G5EDK5), LPHN_DROAN  (B3MFV7), LPHN_DROER  (B3N8M1), 
LPHN_DROGR  (B4J780), LPHN_DROME  (A1Z7G7), LPHN_DROMO  (B4KMZ1), 
LPHN_DROPE  (B4GD14), LPHN_DROPS  (Q292N4), LPHN_DROSE  (B4HS00), 
LPHN_DROVI  (B4LNA8), LPHN_DROYA  (B4P3A0), LPLT1_CAEEL (G5EDW2), 
LPLT2_CAEEL (G5ECX0), PK1L1_HUMAN (Q8TDX9), PK1L1_MOUSE (Q8R526), 
PK1L1_ORYLA (E7FKV8), PK1L2_HUMAN (Q7Z442), PK1L2_MOUSE (Q7TN88), 
PK1L3_HUMAN (Q7Z443), PK1L3_MOUSE (Q2EG98), PK1L_ACRMI  (B8UU59), 
PKD1_CAEEL  (Q09624), PKD1_HUMAN  (P98161), PKD1_MOUSE  (O08852), 
STAN_DROME  (Q9V5N8), SUREJ_STRPU (Q26627)
» more

PDB
[Detailed view]
40 PDB

2BO2; 2BOU; 2BOX; 4DLO; 4DLQ; 5KVM; 6VHH; 7D76; 7D77; 7DO4; 7EPT; 7EQ1; 7QU8; 7SF7; 7SF8; 7WU2; 7WU3; 7WU4; 7WU5; 7WUI; 7WUJ; 7WUQ; 7WXU; 7WXW; 7WY0; 7WY5; 7WY8; 7WYB; 7WZ7; 7X10; 7X2V; 7XKE; 7YDH; 7YDJ; 7YDM; 7YDP; 7YP7; 8IKJ; 8IKL; 8OEK
» more