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PROSITE entry PS50838


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General information about the entry

PURL [info] https://purl.expasy.org/prosite/signature/PS50838
Entry name [info] MAGE
Accession [info] PS50838
Entry type [info] MATRIX
Date [info] 01-DEC-2001 CREATED;
10-MAY-2017 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC50838
Associated ProRule [info] PRU00127

Name and characterization of the entry

Description [info] MAGE conserved domain profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ABCDEFGHIKLMNPQRSTVWYZ'; LENGTH=200;
/DISJOINT: DEFINITION=PROTECT; N1=6; N2=195;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=0.5871000; R2=0.0138858; TEXT='NScore';
/NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=-2320.8032227; R2=32.4210167; PRIORITY=1; TEXT='Heuristic 5.0%';
/CUT_OFF: LEVEL=0; SCORE=678; H_SCORE=19661; N_SCORE=10.0; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=426; H_SCORE=11491; N_SCORE=6.5; MODE=1; TEXT='?';
/DEFAULT: M0=-8; D=-20; I=-20; B1=-60; E1=-60; MI=-105; MD=-105; IM=-105; DM=-105;
...
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Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_01 which contains 572'970 sequence entries.


Total number of hits 61 in 55 different sequences
Number of true positive hits 61 in 55 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 1
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 98.39 %

Comments [info]

Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 2
Matrix type [info] protein_domain
Scaling database [info] reversed
Author [info] CJA_Sigrist
Feature key [info] DOMAIN
Feature description [info] MAGE
Version [info] 5

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
55 sequences

MA13P_HUMAN (A6NCF6), MAB6B_HUMAN (A0A0J9YX57), MAGA1_HUMAN (P43355), 
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UniProtKB/Swiss-Prot
False negative sequences
1 sequence

MAGA5_HUMAN (P43359)

		
PDB
[Detailed view]
10 PDB

1QEW; 2WA0; 4V0P; 5HVQ; 5WY5; 6R7T; 6WJH; 7UOA; 8T9A; 9BD2