Entry: PS50877

General information about the entry

Entry name [info] GOLOCO
Accession [info] PS50877
Entry type [info] MATRIX
Date [info] APR-2003 (CREATED); OCT-2013 (DATA UPDATE); MAY-2015 (INFO UPDATE).
PROSITE Doc. [info] PDOC50877
Associated ProRule [info] PRU00097

Name and characterization of the entry

Description [info] GoLoco/GPR motif profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ABCDEFGHIKLMNPQRSTVWYZ'; LENGTH=23;
/DISJOINT: DEFINITION=PROTECT; N1=3; N2=21;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=0.5159345; R2=0.0172079; TEXT='NScore';
/NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=539.80729; R2=7.72396; TEXT='HScore';
/CUT_OFF: LEVEL=0; SCORE=447; N_SCORE=8.2; H_SCORE=3452; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=348; N_SCORE=6.5; H_SCORE=3228; MODE=1; TEXT='?';
/DEFAULT: M0=-7; D=-20; I=-20; B1=-100; E1=-100; MI=-105; MD=-105; IM=-105; DM=-105;
...
                A   B   C   D   E   F   G   H   I   K   L   M   N   P   Q   R   S   T   V   W   Y   Z
/I:         B1=0; BI=-105; BD=-105;
/M: SY='D'; M=-10,  5,-27,  7,  3,-24, -6, -7,-18, -4,-18,-10,  4, -5,  1, -4, -1, -5,-18,-29,-17,  1;
/M: SY='E'; M=-12, 15,-27, 24, 26,-28,-19, -6,-20,  0,-17,-16,  2, -9,  7, -7, -1, -5,-17,-32,-16, 16;
/M: SY='D'; M=-13, 26,-29, 37, 28,-34, -6,  0,-34,  2,-26,-23, 13, -8, 10, -5,  1,-10,-30,-33,-20, 19;
/M: SY='F'; M=-11,-28,-20,-32,-24, 27,-22,-19, 11,-27, 26, 14,-24,-28,-25,-19,-22,-10,  8,-12,  6,-23;
/M: SY='L'; M=-11,-25,-19,-30,-22, 22,-28,-14, 12,-22, 24, 17,-23,-27,-20,-17,-19, -4,  9,-11, 12,-21;
/M: SY='D'; M= -5, 21,-24, 27, 27,-29,-10, -2,-28,  1,-25,-22, 14, -8,  7, -6,  8, -3,-24,-35,-20, 17;
/M: SY='M'; M= -8,-23,-21,-28,-20,  1,-20,-14, 16,-21, 27, 28,-21,-23,-13,-17,-19, -5,  8,-21, -3,-17;
/M: SY='L'; M= -9,-30,-23,-34,-25,  5,-34,-25, 32,-29, 35, 19,-26,-26,-21,-24,-25, -9, 21,-21, -1,-25;
/M: SY='M'; M= -7, -8,-22,-14, -5, -2,-20, -9,  2, -8,  4, 10, -4,-19, -7, -9,-11, -7, -1,-23, -6, -6;
/M: SY='R'; M=-10, -2,-25, -4,  2,-22,-14, -4,-27, 23,-25,-13,  6,-16,  7, 39,  3, -2,-18,-26,-13,  2;
/M: SY='M'; M= -3,-18, -9,-23,-19, -4,-22, -3,  8,-14,  3, 18,-17,-23,-11,-14, -8, -2, 13,-24,  0,-16;
/I:         I=-6; MD=-29;
/M: SY='Q'; M= -9,  0,-27,  0, 18,-37,-18,  9,-18,  9,-18,  0,  0, -9, 55,  9,  0, -9,-27,-18, -9, 37; D=-6;
/I:         I=-6; MI=0; MD=-29; IM=0; DM=-29;
/M: SY='S'; M=  8, -7, -5, -9,-10,-21, 13,-16,-22,-16,-22,-16,  0,-17,-10,-16, 18,  3,-13,-33,-22,-10;
/M: SY='S'; M=  4, -2,-19, -3, -3,-24, 10, -9,-25, -5,-27,-16,  8,-14,  2, -1, 18,  3,-18,-30,-20, -1;
/M: SY='R'; M=-17,-10,-30,-10, -3,-22, -5, -3,-32, 22,-22,-12,  0,-20,  5, 55, -8,-12,-22,-20,-13, -3;
/M: SY='M'; M=  0,-22,-19,-29,-19,  0,-21,-12, 17,-18, 25, 33,-22,-22, -9,-16,-18, -8, 10,-20, -3,-15;
/M: SY='D'; M=-16, 25,-30, 38, 34,-33,-16, 16,-34,  3,-24,-21, 10, -7, 10, -4, -2,-12,-30,-34,-13, 21;
/M: SY='D'; M=-12, 37,-28, 53, 25,-36,-11, -2,-35,  1,-26,-26, 14, -8,  3, -9,  1, -9,-27,-36,-20, 14;
/M: SY='Q'; M=-10,  0,-30,  0, 20,-40,-20, 10,-20, 10,-20,  0,  0,-10, 60, 10,  0,-10,-30,-20,-10, 40;
/M: SY='R'; M=-20,-10,-30,-10,  0,-20,-20,  0,-30, 30,-20,-10,  0,-20, 10, 70,-10,-10,-20,-20,-10,  0;
/M: SY='C'; M= 10,-11, 12,-16,-16,-20,  6,-21,-20,-17,-19,-15, -6,-20,-16,-19,  9,  2, -8,-32,-23,-16;
/M: SY='E'; M= -6, -4,-22, -2, 13,-17,-18, -1,-16, -5,-10,-10, -4, -5,  2, -4,  3,  3,-15,-30,-12,  6;
/M: SY='L'; M=-11,-24,-25,-24,-13,  6,-27,-19,  8,-21, 16,  8,-23, -1,-17,-19,-20, -9,  1,-20, -5,-16;
/I:         E1=0; IE=-105; DE=-105;
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Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2015_07 which contains 548'872 sequence entries.


Total number of hits 41 in 21 different sequences
Number of true positive hits 41 in 21 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 0
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 100.00 %

Comments [info]

Matrix type [info] protein_domain
Scaling database [info] reversed
Author [info] N_Hulo
Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 4
Feature key [info] DOMAIN
Feature description [info] GoLoco
Version [info] 2

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
21 sequences

GPR1_CAEEL  (Q95QJ7), GPR2_CAEEL  (Q03569), GPSM1_HUMAN (Q86YR5), 
GPSM1_MOUSE (Q6IR34), GPSM1_RAT   (Q9R080), GPSM2_HUMAN (P81274), 
GPSM2_MOUSE (Q8VDU0), GPSM3_HUMAN (Q9Y4H4), GPSM3_MOUSE (Q3U1Z5), 
GPSM3_RAT   (Q6MG88), PCP2_HUMAN  (Q8IVA1), PCP2_MOUSE  (P12660), 
RGS12_HUMAN (O14924), RGS12_MOUSE (Q8CGE9), RGS12_RAT   (O08774), 
RGS14_HUMAN (O43566), RGS14_MOUSE (P97492), RGS14_RAT   (O08773), 
RGS_DROME   (Q9VCX1), RPGP1_HUMAN (P47736), RPGP1_MOUSE (A2ALS5)
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PDB
[Detailed view]
10 PDB

1KJY; 2OM2; 2XNS; 3ONW; 3QI2; 4G5O; 4G5Q; 4G5R; 4G5S; 4JHR

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