Entry: PS50877

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General information about the entry

Entry name [info] GOLOCO
Accession [info] PS50877
Entry type [info] MATRIX
Date [info] APR-2003 (CREATED); OCT-2013 (DATA UPDATE); JUN-2014 (INFO UPDATE).
PROSITE Doc. [info] PDOC50877
Associated ProRule [info] PRU00097

Name and characterization of the entry

Description [info] GoLoco/GPR motif profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ABCDEFGHIKLMNPQRSTVWYZ'; LENGTH=23;
/DISJOINT: DEFINITION=PROTECT; N1=3; N2=21;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=0.5159345; R2=0.0172079; TEXT='NScore';
/NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=539.80729; R2=7.72396; TEXT='HScore';
/CUT_OFF: LEVEL=0; SCORE=447; N_SCORE=8.2; H_SCORE=3452; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=348; N_SCORE=6.5; H_SCORE=3228; MODE=1; TEXT='?';
/DEFAULT: M0=-7; D=-20; I=-20; B1=-100; E1=-100; MI=-105; MD=-105; IM=-105; DM=-105;
...
                A   B   C   D   E   F   G   H   I   K   L   M   N   P   Q   R   S   T   V   W   Y   Z
/I:         B1=0; BI=-105; BD=-105;
/M: SY='D'; M=-10,  5,-27,  7,  3,-24, -6, -7,-18, -4,-18,-10,  4, -5,  1, -4, -1, -5,-18,-29,-17,  1;
/M: SY='E'; M=-12, 15,-27, 24, 26,-28,-19, -6,-20,  0,-17,-16,  2, -9,  7, -7, -1, -5,-17,-32,-16, 16;
/M: SY='D'; M=-13, 26,-29, 37, 28,-34, -6,  0,-34,  2,-26,-23, 13, -8, 10, -5,  1,-10,-30,-33,-20, 19;
/M: SY='F'; M=-11,-28,-20,-32,-24, 27,-22,-19, 11,-27, 26, 14,-24,-28,-25,-19,-22,-10,  8,-12,  6,-23;
/M: SY='L'; M=-11,-25,-19,-30,-22, 22,-28,-14, 12,-22, 24, 17,-23,-27,-20,-17,-19, -4,  9,-11, 12,-21;
/M: SY='D'; M= -5, 21,-24, 27, 27,-29,-10, -2,-28,  1,-25,-22, 14, -8,  7, -6,  8, -3,-24,-35,-20, 17;
/M: SY='M'; M= -8,-23,-21,-28,-20,  1,-20,-14, 16,-21, 27, 28,-21,-23,-13,-17,-19, -5,  8,-21, -3,-17;
/M: SY='L'; M= -9,-30,-23,-34,-25,  5,-34,-25, 32,-29, 35, 19,-26,-26,-21,-24,-25, -9, 21,-21, -1,-25;
/M: SY='M'; M= -7, -8,-22,-14, -5, -2,-20, -9,  2, -8,  4, 10, -4,-19, -7, -9,-11, -7, -1,-23, -6, -6;
/M: SY='R'; M=-10, -2,-25, -4,  2,-22,-14, -4,-27, 23,-25,-13,  6,-16,  7, 39,  3, -2,-18,-26,-13,  2;
/M: SY='M'; M= -3,-18, -9,-23,-19, -4,-22, -3,  8,-14,  3, 18,-17,-23,-11,-14, -8, -2, 13,-24,  0,-16;
/I:         I=-6; MD=-29;
/M: SY='Q'; M= -9,  0,-27,  0, 18,-37,-18,  9,-18,  9,-18,  0,  0, -9, 55,  9,  0, -9,-27,-18, -9, 37; D=-6;
/I:         I=-6; MI=0; MD=-29; IM=0; DM=-29;
/M: SY='S'; M=  8, -7, -5, -9,-10,-21, 13,-16,-22,-16,-22,-16,  0,-17,-10,-16, 18,  3,-13,-33,-22,-10;
/M: SY='S'; M=  4, -2,-19, -3, -3,-24, 10, -9,-25, -5,-27,-16,  8,-14,  2, -1, 18,  3,-18,-30,-20, -1;
/M: SY='R'; M=-17,-10,-30,-10, -3,-22, -5, -3,-32, 22,-22,-12,  0,-20,  5, 55, -8,-12,-22,-20,-13, -3;
/M: SY='M'; M=  0,-22,-19,-29,-19,  0,-21,-12, 17,-18, 25, 33,-22,-22, -9,-16,-18, -8, 10,-20, -3,-15;
/M: SY='D'; M=-16, 25,-30, 38, 34,-33,-16, 16,-34,  3,-24,-21, 10, -7, 10, -4, -2,-12,-30,-34,-13, 21;
/M: SY='D'; M=-12, 37,-28, 53, 25,-36,-11, -2,-35,  1,-26,-26, 14, -8,  3, -9,  1, -9,-27,-36,-20, 14;
/M: SY='Q'; M=-10,  0,-30,  0, 20,-40,-20, 10,-20, 10,-20,  0,  0,-10, 60, 10,  0,-10,-30,-20,-10, 40;
/M: SY='R'; M=-20,-10,-30,-10,  0,-20,-20,  0,-30, 30,-20,-10,  0,-20, 10, 70,-10,-10,-20,-20,-10,  0;
/M: SY='C'; M= 10,-11, 12,-16,-16,-20,  6,-21,-20,-17,-19,-15, -6,-20,-16,-19,  9,  2, -8,-32,-23,-16;
/M: SY='E'; M= -6, -4,-22, -2, 13,-17,-18, -1,-16, -5,-10,-10, -4, -5,  2, -4,  3,  3,-15,-30,-12,  6;
/M: SY='L'; M=-11,-24,-25,-24,-13,  6,-27,-19,  8,-21, 16,  8,-23, -1,-17,-19,-20, -9,  1,-20, -5,-16;
/I:         E1=0; IE=-105; DE=-105;
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Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2014_07 which contains 546'000 sequence entries.


Total number of hits 41 in 21 different sequences
Number of true positive hits 41 in 21 different sequences
Number of 'unknown' hits
Number of false positive hits
Number of false negative sequences 0
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 100.00 %

Comments [info]

Matrix type [info] protein_domain
Scaling database [info] reversed
Author [info] N_Hulo
Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 4
Feature key [info] DOMAIN
Feature description [info] GoLoco
Version [info] 2

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
21 sequences

GPR1_CAEEL  (Q95QJ7), GPR2_CAEEL  (Q03569), GPSM1_HUMAN (Q86YR5), 
GPSM1_MOUSE (Q6IR34), GPSM1_RAT   (Q9R080), GPSM2_HUMAN (P81274), 
GPSM2_MOUSE (Q8VDU0), GPSM3_HUMAN (Q9Y4H4), GPSM3_MOUSE (Q3U1Z5), 
GPSM3_RAT   (Q6MG88), PCP2_HUMAN  (Q8IVA1), PCP2_MOUSE  (P12660), 
RGS12_HUMAN (O14924), RGS12_MOUSE (Q8CGE9), RGS12_RAT   (O08774), 
RGS14_HUMAN (O43566), RGS14_MOUSE (P97492), RGS14_RAT   (O08773), 
RGS_DROME   (Q9VCX1), RPGP1_HUMAN (P47736), RPGP1_MOUSE (A2ALS5)
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PDB
[Detailed view]
10 PDB

1KJY; 2OM2; 2XNS; 3ONW; 3QI2; 4G5O; 4G5Q; 4G5R; 4G5S; 4JHR

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