PROSITE entry PS50960
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General information about the entry
| Entry name [info] | HTH_PSQ |
| Accession [info] | PS50960 |
| Entry type [info] | MATRIX |
| Date [info] |
01-FEB-2004 CREATED;
01-OCT-2013 DATA UPDATE; 29-MAY-2024 INFO UPDATE. |
| PROSITE Doc. [info] | PDOC50960 |
| Associated ProRule [info] | PRU00320 |
Name and characterization of the entry
| Description [info] | Psq-type HTH domain profile. |
| Matrix / Profile [info] |
/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=53; /DISJOINT: DEFINITION=PROTECT; N1=1; N2=53; /NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=3.0544367; R2=0.0002543; TEXT='NScore'; /CUT_OFF: LEVEL=0; SCORE=44615; N_SCORE=14.4; MODE=1; TEXT='R'; /CUT_OFF: LEVEL=-1; SCORE=13943; N_SCORE=6.6; MODE=1; TEXT='R?'; /DEFAULT: B1=*; E1=*; MM=*; II=*; ... A C D E F G H I K L M N P Q R S T V W Y /I: B1=-8455; E0=*; BM=-44; BD=-5044; /M: SY='M'; M= 316,-3779, -583, -470, -482, -946,-1979,-3827, 710, -603, 2002, 428, 1450,-1524, 916, 295, -499, -154,-3971,-3297; M0=-512; /I: MM=-2; MI=-10161; MD=-11203; IM=-894; II=-1115; DM=-701; DD=-1378; /M: SY='P'; M= -814,-3782,-2224,-1675,-4089, 983,-1996,-3826, 1282,-3793,-2879, 952, 1646,-1543, 1313, 669,-2296, 336,-3977, -1; M0=-1041; /I: MM=-2; MI=-10161; MD=-11203; IM=-894; II=-1115; DM=-701; DD=-1378; /M: SY='K'; M= -214,-3781,-2200, 1233, -369, 258, 326,-1346, 2021,-3791,-2874,-1960,-3412,-1524, 1389, -99, 688,-1040,-3972,-3298; M0=-926; /I: MM=-2; MI=-10161; MD=-11203; IM=-894; II=-1115; DM=-701; DD=-1378; /M: SY='R'; M=-2338,-3803, 34, -833,-4121, 342, 1213,-1045, 1308,-3818, 1127, 550,-3406,-1513, 2138, 168, 257,-1050, 1061,-3308; M0=-950; /I: MM=-2; MI=-10161; MD=-11203; IM=-894; II=-1115; DM=-701; DD=-1378; /M: SY='K'; M= -791,-3858,-2257,-1703,-4185, 1547, 327,-3928, 2242,-3870,-2950, 527,-3462,-1559, 1977, -742, -730,-3484,-4033, 0; M0=-1414; /I: MM=-2; MI=-10161; MD=-11203; IM=-894; II=-1115; DM=-701; DD=-1378; /M: SY='K'; M=-1355,-3801,-2189, 181, -679, 21, 595,-1044, 1876,-1894,-2892,-1950, 1761, -444, 1741, -376, -548,-3421,-3987,-3307; M0=-845; /I: MM=-2; MI=-10161; MD=-11203; IM=-894; II=-1115; DM=-701; DD=-1378; /M: SY='R'; M=-2557,-2598,-3945,-3354,-2578,-3965,-2766, -435, -27, 133,-1792,-3252, 1272,-2898, 2787, -247, -459, -510,-3031, 1881; M0=-1266; /I: MM=-2; MI=-10161; MD=-11203; IM=-894; II=-1115; DM=-701; DD=-1378; /M: SY='K'; M=-3141,-4406,-3129,-2461,-4827,-4039, 533,-4469, 2317,-4358,-3509, 926,-4092, -13, 1871,-3029, 1064, 1141, 1681,-3940; M0=-1955; /I: MM=-2; MI=-10161; MD=-11203; IM=-894; II=-1115; DM=-701; DD=-1378; /M: SY='Q'; M= 890,-3807, -440, -704, -420, -945,-1971, -928, -131,-3822,-2896, -121, -618, 1802, -330, 1559, 212, 281,-3991,-3309; M0=-671; /I: MM=-2; MI=-10161; MD=-11203; IM=-894; II=-1115; DM=-701; DD=-1378; /M: SY='W'; M=-2608,-2437,-4924, -982, -237,-4151,-3009, 245,-3890, 1770,-1633,-3786,-4201, -317, -600,-3235,-2548, -713, 3791, 2723; M0=-1727; /I: MM=-2; MI=-10161; MD=-11203; IM=-894; II=-1115; DM=-701; DD=-1378; /M: SY='T'; M= -972,-3844, 81, -391,-4162, -995,-2011,-3911,-1599,-1457,-2938, 538,-3441,-1554, -408, 1439, 2895,-3465,-4032,-3349; M0=-1309; /I: MM=-2; MI=-10161; MD=-11203; IM=-894; II=-1115; DM=-701; DD=-1378; /M: SY='L'; M=-2340,-3791, 33, 1287, -512,-3317, -240, -125, -737, 1723,-2882, -236, 1255, -143, 644,-1329,-2279,-3408,-3979,-3302; M0=-895; /I: MM=-2; MI=-10161; MD=-11203; IM=-894; II=-1115; DM=-701; DD=-1378; /M: SY='E'; M= 544,-3826, 1342, 2462,-4146,-3321,-1983,-3897, 715,-3842,-2915, 1008, -587,-1523, -950,-2231, 216,-3448,-4009, -120; M0=-1368; /I: MM=-2; MI=-10161; MD=-11203; IM=-894; II=-1115; DM=-701; DD=-1378; /M: SY='E'; M= -727,-3799, 1760, 2378, -418,-3314,-1973, -909, -318,-1553, 267, 348,-3407, 753,-2062, 52, -573,-3418,-3986,-3306; M0=-1010; /I: MM=-2; MI=-10161; MD=-11203; IM=-894; II=-1115; DM=-701; DD=-1378; /M: SY='K'; M=-3540,-3460,-5391,-4469, 687,-4898,-3426,-2691, 2843, 1412, 2591,-4191,-4868,-3431, -642,-4043, -666,-2797,-3756,-3481; M0=-2343; /I: MM=-2; MI=-10161; MD=-11203; IM=-894; II=-1115; DM=-701; DD=-1378; /M: SY='M'; M= 844,-3328, 233, 317,-3470,-3471,-2160, 1425, -407, 572, 2185, -853,-3557, 376,-2316, -778, -578, 423,-3631,-3078; M0=-749; /I: MM=-2; MI=-10161; MD=-11203; IM=-894; II=-1115; DM=-701; DD=-1378; /M: SY='E'; M= 1122, 645, 240, 1953,-4139,-3317, -156,-3889, 1060,-3833,-2906, -104,-3410, 1591, 1359,-2224,-2283,-3439,-4000,-3317; M0=-1465; /I: MM=-2; MI=-10161; MD=-11203; IM=-894; II=-1115; DM=-701; DD=-1378; /M: SY='A'; M= 2937,-3890,-7059,-6734,-4551,-6759,-6754, 1294,-6673,-3347, 401,-6488,-6581,-6589,-6800,-6114,-4368, 1829,-6203,-5710; M0=-4137; /I: MM=-2; MI=-10161; MD=-11203; IM=-894; II=-1115; DM=-701; DD=-1378; /M: SY='I'; M=-1079, 809,-7032,-6670,-4362,-6785,-6517, 3027,-6581, 1846,-3108,-6446,-6543,-6420,-6658,-6112,-4363, 882,-5941,-5519; M0=-3871; /I: MM=-2; MI=-10161; MD=-11203; IM=-894; II=-1115; DM=-701; DD=-1378; /M: SY='E'; M= 437,-3810, 53, 1610, -487,-1082, 566,-3882, 600,-1100,-2899, -285,-3404, 1583, 1559, -411, -620,-3432,-3994,-3311; M0=-848; /I: MM=-2; MI=-10161; MD=-11203; IM=-894; II=-1115; DM=-701; DD=-1378; /M: SY='A'; M= 1993, 827, 463, -555,-3898,-3357, 531,-3601,-1637, -76, -487,-2024,-3449, 636, 1643, 200,-2293,-1687,-3874, -108; M0=-976; /I: MM=-2; MI=-10161; MD=-11203; IM=-894; II=-1115; DM=-701; DD=-1378; /M: SY='V'; M=-2586, 911,-4931,-4295, -251,-4134, 379, 1799,-3890, 469,-1615,-3779,-4184, -412,-3690,-1065,-2527, 2527,-2869, 1374; M0=-1753; /I: MM=-2; MI=-10161; MD=-11203; IM=-894; II=-1115; DM=-701; DD=-1378; /M: SY='R'; M=-2338,-3810, 1375, 1649,-4130,-3312, 624,-3880, 268, -619, 334,-1947,-3405, 440, 1830, 2, 432,-3431, 1139,-3311; M0=-1136; /I: MM=-46; MI=-10161; MD=-5045; IM=-894; II=-1115; DM=-701; DD=-1378; /M: SY='N'; M= 124,-3774, 287, 679,-4095, 186,-1933,-1010, 387,-3790,-2863, 1854,-3368,-1474, 1234, 1321, -39,-3396,-3958,-3275; M0=-1011; /I: MM=-2; MI=-10118; MD=-11160; IM=-894; II=-1115; DM=-383; DD=-2100; /M: SY='G'; M=-2354,-3822, -814, 660,-4141, 2824, 327,-3890, 805,-1618,-2913, 300,-3419,-1527,-2077, -783, -597,-1126,-4007,-3325; M0=-1252; /I: MM=-243; MI=-10161; MD=-2700; IM=-894; II=-1115; DM=-701; DD=-1378; /M: SY='K'; M=-2142,-3616, -437, 1473,-3937, 1341,-1774,-3688, 1964,-3632,-2705, 414, 289, 326, 557, -526, -888,-3238,-3799,-3116; M0=-1132; /I: MM=-547; MI=-9921; MD=-1668; IM=-894; II=-1115; DM=-134; DD=-3496; /M: SY='M'; M=-2248,-2076,-4563, 224, -200,-3797,-2669, 1242, -580, 1163, 3674,-3433,-3844,-3161,-3345,-2882, -125, 442,-2537,-2197; M0=-1462; /I: MM=-3; MI=-9715; MD=-10757; IM=-894; II=-1115; DM=-84; DD=-4140; /M: SY='S'; M=-2339,-3805, -396, -384,-4124, -206,-1973,-3872, 254,-3820, 197,-1950, -724,-1514, 240, 2651, 1037,-1125,-3990,-3309; M0=-1223; /I: MM=-2; MI=-10161; MD=-11203; IM=-894; II=-1115; DM=-701; DD=-1378; /M: SY='K'; M= -91,-2447,-4630,-4013, 702,-4087,-2943, -372, 1484, 401, 647,-3635, -250, 1071, 178,-3159, 158, 1307,-2900, 789; M0=-1015; /I: MM=-2; MI=-10161; MD=-11203; IM=-894; II=-1115; DM=-701; DD=-1378; /M: SY='S'; M= 876, 756,-2188,-1639,-4122,-1082, 712,-3871, 1355,-1548, 266, 1080,-1090, 838, 819, 1393, -746,-3425,-3989,-3308; M0=-897; /I: MM=-2; MI=-10161; MD=-11203; IM=-894; II=-1115; DM=-701; DD=-1378; /M: SY='Q'; M= -203,-3811, 240, 1002,-4133,-1310, 1347,-3883, 1901,-3827,-2901,-1947,-3405, 1947, 685, 722, -504,-3433,-3995,-3312; M0=-1267; /I: MM=-2; MI=-10161; MD=-11203; IM=-894; II=-1115; DM=-701; DD=-1378; /M: SY='A'; M= 2551,-3921,-7103,-6771,-4497,-6898,-6826, 1932,-6720, 45,-3208,-6570,-6646,-6618,-6850,-6259,-4412, 1823,-6196,-5729; M0=-3940; /I: MM=-2; MI=-10161; MD=-11203; IM=-894; II=-1115; DM=-701; DD=-1378; /M: SY='A'; M= 2713, 1859,-6151,-6197,-5921, 514,-5418,-5645,-5895,-5925, 1352,-4741,-4822, -338,-5705, 1716,-3576,-4686,-6207,-6053; M0=-3424; /I: MM=-2; MI=-10161; MD=-11203; IM=-894; II=-1115; DM=-701; DD=-1378; /M: SY='R'; M= 489,-3812, -513,-1638,-4133,-1763,-1972,-3884, 1530,-3828,-2901, 583,-3406, 1101, 2740, -273,-1121,-1073,-3995,-3313; M0=-1316; /I: MM=-2; MI=-10161; MD=-11203; IM=-894; II=-1115; DM=-701; DD=-1378; /M: SY='E'; M= 387,-3633, 248, 1637,-1154,-3362,-2030, 963, 752, -108, 1314, -372,-3453,-1599, 1297,-2276, -749,-3214,-3864, -755; M0=-792; /I: MM=-2; MI=-10161; MD=-11203; IM=-894; II=-1115; DM=-701; DD=-1378; /M: SY='F'; M=-5919,-5209,-6955,-7045, 3573,-6680, 640, -699,-6589, 670,-4395,-5514,-6575,-5563, -243,-5882,-5809,-5009,-2531, 2914; M0=-3954; /I: MM=-2; MI=-10161; MD=-11203; IM=-894; II=-1115; DM=-701; DD=-1378; /M: SY='G'; M=-3680,-5361, 391, -537,-5614, 3058, 501,-5439, -601,-5348,-4523, 1717,-4412, -176,-3676, -929,-3678,-4956,-5526,-4689; M0=-2502; /I: MM=-2; MI=-10161; MD=-11203; IM=-894; II=-1115; DM=-701; DD=-1378; /M: SY='I'; M=-4470, 2775,-7166,-6853,-4574,-7034,-7098, 2898,-6834, 399,-3256,-6688,-6741,-6774,-7008,-6424,-4460, 2297,-6384,-5890; M0=-4318; /I: MM=-2; MI=-10161; MD=-11203; IM=-894; II=-1115; DM=-701; DD=-1378; /M: SY='P'; M= -916, 705, -418,-1734,-3912, -241,-2032,-3616, -415,-1495,-2767, -229, 3171,-1598,-2138, 990, -626,-3243, 1062,-3247; M0=-1143; /I: MM=-2; MI=-10161; MD=-11203; IM=-894; II=-1115; DM=-701; DD=-1378; /M: SY='H'; M= -877,-3785,-2197, 141, -417,-1191, 1497, -972, 1063,-3797, 286, -211, 131, 709, 1318, 374, -486, -905, 978, 1409; M0=-553; /I: MM=-2; MI=-10161; MD=-11203; IM=-894; II=-1115; DM=-701; DD=-1378; /M: SY='S'; M=-2417,-3896, -569, -530,-4216, 360,-2042,-3969,-1634,-3912,-2988, 500, 243, -36, 697, 2606, 583,-3518,-4079,-3392; M0=-1364; /I: MM=-2; MI=-10161; MD=-11203; IM=-894; II=-1115; DM=-701; DD=-1378; /M: SY='T'; M=-3294,-3930,-5183,-5494,-6488,-4128,-5389,-6351,-5546,-6549,-5627,-4606,-4916, 1881,-5475, -103, 3726,-5095,-6633,-6477; M0=-4117; /I: MM=-2; MI=-10161; MD=-11203; IM=-894; II=-1115; DM=-701; DD=-1378; /M: SY='L'; M=-1262,-4298,-7318,-6836, 616,-6991,-6133, 1725,-6654, 2626,-2315,-6665,-6524,-5973,-6439,-6279,-4722, 976,-5167,-5116; M0=-3771; /I: MM=-2; MI=-10161; MD=-11203; IM=-894; II=-1115; DM=-701; DD=-1378; /M: SY='W'; M= -202,-3667,-2266, 284,-3925,-3352,-2018,-1306, 175,-1447,-2772, -181,-3444, 51, 1676, 992,-2291, -321, 2647, 2392; M0=-940; /I: MM=-2; MI=-10161; MD=-11203; IM=-894; II=-1115; DM=-701; DD=-1378; /M: SY='R'; M=-2340,-3782, 1505,-1651, -392, 1000,-1979,-3831, -234, -615, 348, -306,-3412, 624, 1748, -158, 610,-3397,-3973, 927; M0=-825; /I: MM=-2; MI=-10161; MD=-11203; IM=-894; II=-1115; DM=-701; DD=-1378; /M: SY='W'; M=-2615,-2606,-4164, -892, -277,-4046, 1452, 2566, 1005,-2461,-1803,-3391,-4102,-3036, 1305,-3094,-2553, -613, 2631, 1512; M0=-1580; /I: MM=-2; MI=-10161; MD=-11203; IM=-894; II=-1115; DM=-701; DD=-1378; /M: SY='C'; M= 344, 2433,-4924,-4288, -126,-4132,-3003,-1903, -49, 1410, 1448,-3776,-4182,-3509, -765,-3216,-2525, 1981,-2870, 994; M0=-1576; /I: MM=-2; MI=-10161; MD=-11203; IM=-894; II=-1115; DM=-701; DD=-1378; /M: SY='K'; M= -129,-3825, 249,-1651,-4147,-3325, 327,-3897, 2500,-3840,-2914, 1159,-3418, 1604, 1525, -880,-2292,-3448,-4005, -181; M0=-1506; /I: MM=-2; MI=-10161; MD=-11203; IM=-894; II=-1115; DM=-701; DD=-1378; /M: SY='R'; M= -900,-3817, 688, 746,-4138, 530, 1341,-3889, 1364,-3833,-2906, 1648,-3409, -85, 1941, -829,-2283,-3439,-4000,-3317; M0=-1288; /I: MM=-2; MI=-10161; MD=-11203; IM=-894; II=-1115; DM=-701; DD=-1378; /M: SY='K'; M=-1144,-3925,-2425, 1055,-4249,-3501,-2115,-3966, 2392, -216,-3022,-2146,-3585, -350, 2099,-2426, 252, -82,-4086,-3454; M0=-1359; /I: MM=-2; MI=-10161; MD=-11203; IM=-894; II=-1115; DM=-701; DD=-1378; /M: SY='G'; M= 242,-3810, -42, 1170,-4132, 1256, 1099,-3882, 961,-2233,-2900, 843, 182, 426,-2057,-1326, 172,-3432,-3994, 862; M0=-849; /I: MM=-2; MI=-10161; MD=-11203; IM=-894; II=-1115; DM=-701; DD=-1378; /M: SY='K'; M= 5,-3792, -489, 203,-4105, 368,-1975, 1289, 1754, -564, 258, -236,-3409, 1498,-2065, -817, -548,-3410,-3981, -59; M0=-722; /I: MM=-2; MI=-10161; MD=-11203; IM=-894; II=-1115; DM=-701; DD=-1378; /M: SY='I'; M= -842, 932,-1034, -50, 573,-4044,-2885, 1802, -837, 979, 1519,-3506, -646,-3197, 169, -964, 161, 338,-2933,-2576; M0=-711; /I: B0=*; E1=-1000;» more |
Numerical results [info]
| Total number of hits | 39 in 37 different sequences |
| Number of true positive hits | 39 in 37 different sequences |
| Number of 'unknown' hits | 0 |
| Number of false positive hits | 0 |
| Number of false negative sequences | 0 |
| Number of 'partial' sequences | 0 |
| Precision (true positives / (true positives + false positives)) | 100.00 % |
| Recall (true positives / (true positives + false negatives)) | 100.00 % |
Comments [info]
| Taxonomic range [info] | Eukaryotes |
| Maximum number of repetitions [info] | 2 |
| Matrix type [info] | protein_domain |
| Scaling database [info] | window20 |
| Author [info] | PS_Langendijk_Genevaux |
| Feature key [info] | DOMAIN |
| Feature description [info] | HTH psq-type |
| Version [info] | 4 |
Cross-references [info]
| UniProtKB/Swiss-Prot True positive sequences |
37 sequences
BAB1_DROME (Q9W0K7), BAB2_DROME (Q9W0K4), CENP1_HUMAN (B2RD01), CENPB_CRIGR (P48988), CENPB_HUMAN (P07199), CENPB_MOUSE (P27790), DANR_DROME (Q9VBW9), DANR_DROPS (Q29CW0), DAN_AEDAE (Q16IB4), DAN_CULQU (B0X560), DAN_DROME (Q9VBW6), DAN_DROPS (Q29CW2), JERKL_HUMAN (Q9Y4A0), JERKL_MOUSE (B2RRL2), JERKY_HUMAN (O75564), JERKY_MOUSE (Q60976), LCORL_CHICK (Q5ZJK5), LCORL_HUMAN (Q8N3X6), LCORL_MOUSE (Q3U285), LCOR_HUMAN (Q96JN0), LCOR_MOUSE (Q6ZPI3), LOV_DROME (P14083), MBLK1_APIME (Q95YM8), MBR1_CAEEL (G5EGQ5), TIGD1_HUMAN (Q96MW7), TIGD2_HUMAN (Q4W5G0), TIGD2_MOUSE (Q0VBL1), TIGD3_HUMAN (Q6B0B8), TIGD3_MOUSE (Q7TM95), TIGD4_HUMAN (Q8IY51), TIGD4_MOUSE (Q8BUZ3), TIGD5_BOVIN (G3MY25), TIGD5_HUMAN (Q53EQ6), TIGD5_MOUSE (Q499M4), TIGD5_RAT (B1WC39), TIGD6_HUMAN (Q17RP2), TIGD7_HUMAN (Q6NT04)» more
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| PDB [Detailed view] |
4 PDB
1BW6; 1HLV; 2COB; 2ELH |