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	Entry: PS51072

General information about the entry
Entry name	MHD
Accession number	PS51072
Entry type	MATRIX
Date	JAN-2005 (CREATED); JAN-2005 (DATA UPDATE); MAR-2013 (INFO UPDATE).
PROSITE Documentation	PDOC51072
Associated ProRule	PRU00404
Name and characterization of the entry
Description	Mu homology domain (MHD) profile.
Matrix / Profile	/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=278; /DISJOINT: DEFINITION=PROTECT; N1=6; N2=273; /NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=3.2027133; R2=0.0216372; TEXT='-LogE'; /CUT_OFF: LEVEL=0; SCORE=245; N_SCORE=8.5; MODE=1; TEXT='!'; /CUT_OFF: LEVEL=-1; SCORE=153; N_SCORE=6.5; MODE=1; TEXT='?'; /DEFAULT: B1=; E1=; MM=; II=; A C D E F G H I K L M N P Q R S T V W Y /I: B1=-85; E0=; BD=-58; /M: SY='K'; M=-10, -3, -7,-12, -6,-19, 11, -9, 23,-32,-18, 4, -4, 8, 6, -3, -5, -8,-47, 11; M0=-6; /I: MM=0; MI=-109; MD=-120; IM=-9; II=-11; DM=-7; DD=-14; /M: SY='Y'; M=-31,-41, -7,-26,-31,-12, 21, -4, -2,-23,-32, -8, 5,-24, -9,-10, -4, -2,-44, 38; M0=-12; /I: MM=0; MI=-109; MD=-120; IM=-9; II=-11; DM=-7; DD=-14; /M: SY='K'; M= -3,-45, -2, 3, -8, 2, 3,-21, 18,-24,-36, -1, 2, -2, 8, 5, 9,-20,-47,-40; M0=-6; /I: MM=0; MI=-109; MD=-120; IM=-9; II=-11; DM=-7; DD=-14; /M: SY='K'; M=-30,-45, -4, -2,-48,-40,-26,-46, 24,-45, 12, 18,-41, 6, 14, -2, 2,-20,-47,-40; M0=-17; /I: MM=0; MI=-109; MD=-120; IM=-9; II=-11; DM=-7; DD=-14; /M: SY='N'; M=-17,-51, 6, 10,-54,-43,-30,-52, -9,-51,-42, 38,-27, 4,-19,-17,-35,-47,-53,-45; M0=-25; /I: MM=0; MI=-109; MD=-120; IM=-9; II=-11; DM=-7; DD=-14; /M: SY='E'; M=-13,-46,-29, 33,-49, 1,-27,-46,-16,-46,-37,-27, 6, -1,-12, -2,-30,-23,-48,-41; M0=-19; /I: MM=0; MI=-109; MD=-120; IM=-9; II=-11; DM=-7; DD=-14; /M: SY='I'; M= 2,-47,-77,-73, 7,-74,-68, 27,-72, 3, 0,-71,-71,-68,-71,-67,-51, 23,-62,-59; M0=-40; /I: MM=0; MI=-109; MD=-120; IM=-9; II=-11; DM=-7; DD=-14; /M: SY='F'; M=-32,-13,-21,-18, 32,-46, 21,-18,-36, -2,-25, -8,-46, -4,-38,-15, -5,-28,-38, 29; M0=-18; /I: MM=0; MI=-109; MD=-120; IM=-9; II=-11; DM=-7; DD=-14; /M: SY='I'; M=-14,-42,-70,-64, 13,-64,-54, 22,-61, 18,-12,-60,-59,-58,-60,-55,-19, 19,-51,-48; M0=-33; /I: MM=0; MI=-109; MD=-120; IM=-9; II=-11; DM=-7; DD=-14; /M: SY='D'; M=-30,-44, 34,-16,-47,-40, 3,-21,-11,-24,-35, -6,-41,-22, 1, -2, 8,-11,-46, -2; M0=-16; /I: MM=0; MI=-109; MD=-120; IM=-9; II=-11; DM=-7; DD=-14; /M: SY='V'; M=-19, -4,-70,-65,-12,-65,-57, 25,-63, -8, 0,-62,-64,-60,-62,-57,-13, 30,-54,-51; M0=-35; /I: MM=0; MI=-109; MD=-120; IM=-9; II=-11; DM=-7; DD=-14; /M: SY='I'; M=-18, -5,-17, 11,-45,-40, -3, 18, 3, -5,-34, 6,-41,-16, -7,-10, 2, 18,-45,-13; M0=-10; /I: MM=0; MI=-109; MD=-120; IM=-9; II=-11; DM=-7; DD=-14; /M: SY='E'; M=-61,-77, 7, 38,-81,-57,-52,-83,-57,-80,-76,-44,-63,-50,-67,-57,-62,-77,-78,-71; M0=-55; /I: MM=0; MI=-109; MD=-120; IM=-9; II=-11; DM=-7; DD=-14; /M: SY='K'; M=-14,-45,-18, 12,-48,-40, -5,-25, 18,-45,-36, 11,-41,-11, 15, 10, 9, -4,-47,-11; M0=-13; /I: MM=0; MI=-109; MD=-120; IM=-9; II=-11; DM=-7; DD=-14; /M: SY='I'; M=-20, -3,-63,-57, 1,-55,-44, 25,-53, 14, 4,-52,-55,-49,-51,-46,-38, 21,-42,-12; M0=-28; /I: MM=0; MI=-109; MD=-120; IM=-9; II=-11; DM=-7; DD=-14; /M: SY='N'; M=-30,-45, 10, 0,-48,-40, -5,-12, -6,-45,-36, 29,-41, 3,-27, 12, 9,-17, 5,-22; M0=-16; /I: MM=0; MI=-109; MD=-120; IM=-9; II=-11; DM=-7; DD=-14; /M: SY='C'; M= 16, 26,-56,-50, -6,-10,-37, 2,-46, 8, 14,-45,-49,-42,-44,-18,-18, 19,-36, 0; M0=-18; /I: MM=0; MI=-109; MD=-120; IM=-9; II=-11; DM=-7; DD=-14; /M: SY='I'; M= -9, -8,-56, 3,-13,-48,-37, 17, -8, 16, 2,-45,-49,-30, -4,-39, 14, 8,-36,-32; M0=-15; /I: MM=0; MI=-109; MD=-120; IM=-9; II=-11; DM=-7; DD=-14; /M: SY='M'; M=-14, 8,-57,-50, 7,-49,-37, 16,-46, 7, 28,-45,-49, 0,-44,-40,-33, 20,-36, 10; M0=-22; /I: MM=0; MI=-109; MD=-120; IM=-9; II=-11; DM=-7; DD=-14; /M: SY='N'; M= -2,-45, 17, -8,-48, 4,-26,-46, -7,-45,-36, 18,-41, -2, -3, 18, 2,-41,-47, 2; M0=-14; /I: MM=0; MI=-109; MD=-53; IM=-9; II=-11; DM=-7; DD=-14; /M: SY='R'; M= 1, -4, -5,-23, 0,-27,-26,-45, 19,-13,-35,-14, 6, 3, 21, 11,-29,-41,-46,-39; M0=-12; /I: MM=-22; MI=-109; MD=-3; IM=-9; II=-11; DM=-16; DD=-6; /M: SY='K'; M=-12,-27,-11, 16,-30, -2, -9,-28, 20, -8,-18, -8,-23, 9, 6, 0, 3,-23,-29,-22; M0=-7; /I: MM=-6; MI=-16; MD=-97; IM=-34; II=-1; DM=0; DD=-51; /M: SY='D'; M=-22,-45, 22, 13,-15,-10, 3,-45, 3,-45,-36, 18,-41, 10,-15, 6, -4,-23,-46,-40; M0=-14; /I: MM=0; MI=-109; MD=-120; IM=-9; II=-11; DM=-4; DD=-20; /M: SY='G'; M=-17,-66, -8,-15,-70, 34,-43,-69,-45, -8,-61, 12,-55,-40,-31,-47,-19,-63,-70,-60; M0=-31; /I: MM=0; MI=-109; MD=-120; IM=-9; II=-11; DM=-7; DD=-14; /M: SY='Q'; M= -9,-12,-17, 1,-48, 5,-14, -6, 10,-45,-11, 8,-41, 14, -7, 11, 12, -2,-47, -4; M0=-9; /I: MM=0; MI=-109; MD=-120; IM=-9; II=-11; DM=-7; DD=-14; /M: SY='I'; M=-15,-31,-56,-21,-17,-48,-37, 21,-46, 14,-23,-45, 3,-42,-44,-16, 2, 20,-36,-10; M0=-18; /I: MM=0; MI=-109; MD=-120; IM=-9; II=-11; DM=-7; DD=-14; /M: SY='L'; M=-18, 5, -3, 1,-39,-43, -7, 9, -3, 17, 3,-31,-43, 3, -2, -2,-30, 13,-41,-36; M0=-10; /I: MM=0; MI=-109; MD=-120; IM=-9; II=-11; DM=-7; DD=-14; /M: SY='R'; M=-16,-45, -4,-11, 2,-22, 11,-46, 11,-13,-36, 11,-41, 3, 16, 11, 8, -8,-47, -4; M0=-9; /I: MM=0; MI=-109; MD=-120; IM=-9; II=-11; DM=-7; DD=-14; /M: SY='S'; M= 12, 13,-55,-49, 1, 7, 0,-26,-45, -9, 9, 3,-49, -4,-43, 20,-32, -5, 10, -1; M0=-14; /I: MM=0; MI=-109; MD=-120; IM=-9; II=-11; DM=-7; DD=-14; /M: SY='E'; M=-10,-45, 14, 25, -9,-40, 15,-16,-17,-21,-36, -7,-41, 2,-12, 0, -8,-13,-47, 13; M0=-11; /I: MM=0; MI=-109; MD=-120; IM=-9; II=-11; DM=-7; DD=-14; /M: SY='V'; M= -4,-46,-77,-73,-52,-74,-72, 27,-72, -2,-11,-23,-72,-71,-73,-67,-50, 28,-67,-62; M0=-42; /I: MM=0; MI=-109; MD=-120; IM=-9; II=-11; DM=-7; DD=-14; /M: SY='Q'; M= -8,-13, 11,-24,-19,-40, 16,-14, 8, -1,-25, 4,-41, 23, -2, 4,-10, -2,-46, -1; M0=-8; /I: MM=0; MI=-109; MD=-120; IM=-9; II=-11; DM=-7; DD=-14; /M: SY='G'; M=-15,-45,-73,-77,-73, 37,-66,-71,-73,-74,-64,-57,-56,-67,-69,-20, -6,-11,-75,-75; M0=-47; /I: MM=0; MI=-109; MD=-120; IM=-9; II=-11; DM=-7; DD=-14; /M: SY='T'; M= -3, 1, 6, 5,-48,-40,-15,-20, 9,-19, 0, -4,-41, 11, 5, -2, 17, 7,-47,-10; M0=-8; /I: MM=0; MI=-109; MD=-120; IM=-9; II=-11; DM=-7; DD=-14; /M: SY='I'; M=-53, -4,-79,-75, -7,-76,-71, 28,-73, 9, 9,-73,-73,-70,-73,-69,-45, 23,-63,-61; M0=-44; /I: MM=0; MI=-109; MD=-120; IM=-9; II=-11; DM=-7; DD=-14; /M: SY='Q'; M= -8, -6, 12, 4, -5,-40, 2, -4, 6,-15, -1, 9,-41, 17, 1, 0, 0, -2,-46, 2; M0=-6; /I: MM=0; MI=-109; MD=-120; IM=-9; II=-11; DM=-7; DD=-14; /M: SY='C'; M= -8, 32,-60,-54, 3,-53,-42, 10,-50, 18, 29,-49,-53,-46,-48,-37,-36, 7,-40,-37; M0=-26; /I: MM=0; MI=-109; MD=-120; IM=-9; II=-11; DM=-7; DD=-14; /M: SY='K'; M=-30, 14,-29,-14,-48,-40, 2,-20, 22, -6,-35, 8,-41, 6, 22,-13, 5,-17,-46,-40; M0=-14; /I: MM=0; MI=-109; MD=-120; IM=-9; II=-11; DM=-7; DD=-14; /M: SY='C'; M= 1, 37,-65,-61,-44,-49,-49, 17,-57,-42,-36, 1,-54,-53,-55, 20, -5, 10,-49,-46; M0=-28; /I: MM=0; MI=-109; MD=-120; IM=-9; II=-11; DM=-7; DD=-14; /M: SY='Y'; M=-15,-45,-13,-12, 19,-13, 23,-45, 10,-19, -9, 12,-41, -1, -3, -1,-10,-31,-47, 25; M0=-11; /I: MM=0; MI=-109; MD=-120; IM=-9; II=-11; DM=-7; DD=-14; /M: SY='L'; M=-32,-33, 6,-17,-33,-46,-34, -3,-19, 27,-25, 9,-47,-34,-38,-22, -5, -8,-38,-14; M0=-17; /I: MM=0; MI=-109; MD=-120; IM=-9; II=-11; DM=-7; DD=-14; /M: SY='S'; M=-21,-45, -4, 6,-48,-33, 2,-45,-12,-23,-36, 1, 13,-12,-14, 26, 10,-19,-47,-40; M0=-14; /I: MM=0; MI=-109; MD=-120; IM=-9; II=-11; DM=-7; DD=-14; /M: SY='G'; M=-18,-63, 6, 3,-65, 33,-40,-64, -2,-63,-55, -2,-52,-36,-46,-13,-12,-59,-65,-56; M0=-29; /I: MM=0; MI=-109; MD=-120; IM=-9; II=-11; DM=-7; DD=-14; /M: SY='M'; M=-14, 2,-12,-49, -3,-22, -6,-11,-45, 5, 39, 12,-20,-14,-43, -7, -4, 1,-36, 9; M0=-12; /I: MM=-1; MI=-37; MD=-120; IM=-6; II=-16; DM=-7; DD=-14; /M: SY='P'; M= -4, -7,-48,-43,-34, -3,-36,-17,-16,-17,-26,-18, 37,-38,-41, 4,-16,-10,-38,-35; M0=-18; /I: MM=0; MI=-109; MD=-120; IM=-9; II=-11; DM=-7; DD=-14; /M: SY='E'; M=-15,-45, 16, 22, -9,-40, 7, -9, 4, -3,-36, -4,-20, 3, 5,-29, -6, -9,-47, 1; M0=-8; /I: MM=0; MI=-109; MD=-120; IM=-9; II=-11; DM=-7; DD=-14; /M: SY='C'; M=-15, 36,-67,-62,-41,-61,-52, 22,-59, 16, 5,-58,-61,-56,-58,-24,-42, 14,-50,-46; M0=-32; /I: MM=0; MI=-109; MD=-120; IM=-9; II=-11; DM=-7; DD=-14; /M: SY='K'; M=-13,-19,-29, 6,-11,-40, -2, -1, 19,-13,-36,-13,-41, 9, 19, 1, 13,-41,-47,-40; M0=-12; /I: MM=0; MI=-109; MD=-120; IM=-9; II=-11; DM=-7; DD=-14; /M: SY='L'; M=-64,-58,-88,-83, 16,-87,-74, 18,-81, 24, 18,-84,-76,-68,-76,-81,-63, 9,-58,-61; M0=-50; /I: MM=0; MI=-109; MD=-120; IM=-9; II=-11; DM=-7; DD=-14; /M: SY='G'; M= 1, -5,-29,-14,-15, 24, -5,-12, 6,-25,-35, -7,-15, 3, -6, 9, 3,-26,-46,-11; M0=-8; /I: MM=0; MI=-109; MD=-120; IM=-9; II=-11; DM=-7; DD=-14; /M: SY='L'; M=-45,-42,-69,-63, 16,-62,-50, 7,-59, 27, 7,-58,-61,-54,-56,-24, -4, -2,-46,-44; M0=-32; /I: MM=0; MI=-109; MD=-120; IM=-9; II=-11; DM=-7; DD=-14; /M: SY='N'; M= -5,-45, -3, -5,-48, -4,-26,-22,-12,-22, 5, 35,-41,-22, -7, 6, -2,-41,-47,-40; M0=-14; /I: MM=0; MI=-109; MD=-120; IM=-9; II=-11; DM=-7; DD=-14; /M: SY='D'; M= -7,-45, 27, 5,-48, -7, -4,-46, 1,-17,-36, 20, -5, -2,-13, -9, -4,-41,-47,-40; M0=-13; /I: MM=0; MI=-109; MD=-120; IM=-9; II=-11; DM=-7; DD=-14; /M: SY='K'; M=-13,-45, 1, 6,-48, -1, -5, -7, 18, -5, 6, 5, 13, -9, 1, -1, -3,-18,-47,-40; M0=-6; /I: MM=0; MI=-109; MD=-120; IM=-9; II=-11; DM=-7; DD=-14; /M: SY='V'; M= -5,-36, 6,-13, 1, 4,-10, 7, -9, 6, 0,-33,-10,-14, 4, -2, -1, 8, 5, 5; M0=-3; /I: MM=-2; MI=-109; MD=-28; IM=-9; II=-11; DM=-7; DD=-14; /M: SY='C'; M= -7, 12, 1, -8,-27,-15, -3, 4, -4, 9, 5, 11,-39, 0, -1, 3, 11, -9,-44, -7; M0=-4; /I: MM=-3; MI=-107; MD=-25; IM=-9; II=-11; DM=-34; DD=-1; /M: SY='F'; M= -7,-28,-41,-35, 20,-10, -1, 12, 4, 3, 7,-14,-16, 10, -2, -8,-27, 11,-33,-29; M0=-8; /I: MM=-1; MI=-104; MD=-44; IM=-9; II=-11; DM=-43; DD=-1; /M: SY='G'; M=-11,-40, 10, 9,-43, 19, 13,-41, 13,-12,-31, -3,-36, 2, -3, -3,-18,-15,-42,-35; M0=-10; /I: MM=-1; MI=-104; MD=-45; IM=-9; II=-11; DM=-44; DD=-1; /M: SY='K'; M= -2,-39, 5,-18,-42, -2, 0, -8, 14, -5,-10, 12,-15, 10, 9, -1, 4, -4,-41,-34; M0=-5; /I: MM=-3; MI=-103; MD=-23; IM=-9; II=-11; DM=-45; DD=-1; /M: SY='E'; M= -8,-37, 12, 15,-40,-13, 9, -2, 3,-24,-27, 3,-32, 12, -7, 6, 1, -2,-38, -6; M0=-6; /I: MM=-42; MI=-3; MD=-29; IM=-38; II=-1; DM=-41; DD=-1; /M: SY='K'; M= 6,-35, -9, -1,-38, 4, 0,-14, 16,-35, 1, 1,-31, -2, 9, 6, 10, -6,-37,-30; M0=-7; /I: MM=0; MI=-98; MD=-108; IM=-9; II=-11; DM=-46; DD=-1; /M: SY='K'; M= 7,-35, 3, -7,-38, 2,-17,-16, 12,-35,-26, -5, 3, 1, 2, 10, 3, 2,-37, -3; M0=-6; /I: MM=0; MI=-98; MD=-109; IM=-9; II=-11; DM=-51; /M: SY='N'; M= 1,-35, -2, 3,-38, 0, 3,-36, 12,-35,-26, 13,-12,-12, 8, 10, 7,-31,-37, 9; M0=-8; /I: MM=0; MI=-98; MD=-109; IM=-9; II=-11; DM=-51; /M: SY='G'; M= 3,-35,-19, 3,-38, 16,-17,-36, 10,-35,-26, 11,-31, 6, -3, 8, 8,-31,-37, -7; M0=-10; /I: MM=0; MI=-98; MD=-109; IM=-9; II=-11; DM=-37; DD=-1; /M: SY='K'; M= -1,-36,-20, 8,-39, 11, 3,-37, 18,-17,-27, 15, -4, -6, 1, 1, -5,-20,-38,-31; M0=-8; /I: MM=0; MI=-99; MD=-109; IM=-9; II=-11; DM=-50; /M: SY='W'; M= 6,-33,-22, -8,-11, 15,-19,-31,-15,-24,-24, 11,-33,-15, 0, 17, 4,-18, 26,-29; M0=-9; /I: MM=0; MI=-99; MD=-109; IM=-9; II=-11; DM=-34; DD=-1; /M: SY='I'; M=-39,-35,-64,-59, -7,-59,-51, 29,-56, -2, -8,-55,-58,-53,-55, 0,-38, 25,-47,-44; M0=-31; /I: MM=0; MI=-100; MD=-110; IM=-9; II=-11; DM=-16; DD=-6; /M: SY='E'; M= -9,-38, 10, 14, 5,-19,-22, 11, 8,-17,-25,-22, 12,-17, 10,-24, -2, -6,-40,-34; M0=-7; /I: MM=0; MI=-104; MD=-114; IM=-9; II=-11; DM=-14; DD=-7; /M: SY='M'; M=-31,-29,-54,-48,-10,-13,-35, 20,-44, 22, 22,-43,-47,-40,-42, -6, -8, 3,-33,-30; M0=-20; /I: MM=0; MI=-106; MD=-116; IM=-9; II=-11; DM=-22; DD=-4; /M: SY='D'; M=-18, 0, 25, 21, -5, -5, -2,-43, -5,-15,-33,-13,-38, 7,-12, -7,-27,-17,-44, -2; M0=-11; /I: MM=0; MI=-107; MD=-117; IM=-9; II=-11; DM=-1; DD=-43; /M: SY='D'; M= -2,-45, 29, -4,-48,-15,-26,-11, 3,-14,-36, 10,-41, 21,-16,-22,-29,-41,-47,-40; M0=-15; /I: MM=0; MI=-109; MD=-120; IM=-9; II=-11; DM=-7; DD=-14; /M: SY='C'; M=-13, 36,-56,-50, 13,-21,-37, 10,-46, 4, -8,-45, 0,-42,-44,-14,-16, 19,-36, 6; M0=-17; /I: MM=0; MI=-109; MD=-120; IM=-9; II=-11; DM=-7; DD=-14; /M: SY='K'; M= -9,-45,-29, -7,-48,-12, 10,-12, 22,-21,-36, 1,-41, 18, 10, 10, -2,-15,-47,-40; M0=-11; /I: MM=0; MI=-109; MD=-120; IM=-9; II=-11; DM=-7; DD=-14; /M: SY='F'; M=-35,-33,-58,-52, 39,-50,-39, -8,-19, -4, -5,-47,-51,-44,-46,-41, 16, -2,-37,-10; M0=-26; /I: MM=0; MI=-109; MD=-120; IM=-9; II=-11; DM=-7; DD=-14; /M: SY='H'; M=-47,-54,-46,-49,-63,-53, 54,-74,-59,-74,-67,-13,-60,-55,-62,-19,-51,-64,-66,-58; M0=-51; /I: MM=0; MI=-109; MD=-120; IM=-9; II=-11; DM=-7; DD=-14; /M: SY='P'; M=-30,-45, -7, 3,-15,-20, 10,-45,-15,-45,-36,-26, 29, 26, 2, -3,-17,-20,-47,-11; M0=-16; /I: MM=0; MI=-109; MD=-120; IM=-9; II=-11; DM=-7; DD=-14; /M: SY='C'; M=-22, 50,-56,-50,-33,-48,-14, -4,-47,-18,-25, 21,-49,-43,-45, 2, -8,-16,-38,-34; M0=-26; /I: MM=0; MI=-109; MD=-120; IM=-9; II=-11; DM=-7; DD=-14; /M: SY='V'; M=-13,-47,-79,-76,-54,-78,-79, 15,-76, -5,-41,-74,-75,-76,-78,-72,-52, 35,-72,-67; M0=-48; /I: MM=0; MI=-109; MD=-120; IM=-9; II=-11; DM=-7; DD=-14; /M: SY='D'; M=-30,-45, 24, 3,-48,-21,-11,-46, 4,-25,-36, 17,-41, 2, 20, -8, -1,-41,-47,-40; M0=-16; /I: MM=0; MI=-109; MD=-52; IM=-9; II=-11; DM=-7; DD=-14; /M: SY='L'; M=-12,-32,-47,-11, 0,-46,-35, -7, 20, 21,-24,-40,-47,-10, -4, -9,-20, -9, 3, 3; M0=-13; /I: MM=0; MI=-109; MD=-119; IM=-9; II=-11; DM=-3; DD=-24; /M: SY='N'; M= 4,-45, 12, 4,-48, -4, -8,-46, 14,-23,-36, 16, -4, -5,-11, 13, -6,-23,-47,-40; M0=-10; /I: MM=0; MI=-109; MD=-120; IM=-9; II=-11; DM=-7; DD=-14; /M: SY='K'; M=-17,-45, -3, 11,-48,-14,-26,-45, 20, 4,-11, -5,-14, -5, 15, 3,-18, -2,-47,-40; M0=-9; /I: MM=-3; MI=-30; MD=-44; IM=-20; II=-4; DM=-7; DD=-14; /M: SY='F'; M=-25,-42,-65,-61, 38,-59, -3,-10,-57,-10,-34,-53,-59,-51,-54,-47,-44, -2, 35, 18; M0=-33; /I: MM=0; MI=-109; MD=-119; IM=-9; II=-11; DM=-2; DD=-28; /M: SY='E'; M= -3,-45, 10, 22,-14, -7, 1,-45, 2,-18, -9, 15,-41, 0, -9, -9, 7,-41,-47,-12; M0=-10; /I: MM=0; MI=-109; MD=-120; IM=-9; II=-11; DM=-7; DD=-14; /M: SY='S'; M=-12,-45, -4, -2,-36,-21, -9, -6, 4,-29,-36, 16, -9, 9, -5, 22, 4,-10,-47,-40; M0=-9; /I: MM=0; MI=-109; MD=-120; IM=-9; II=-11; DM=-7; DD=-14; /M: SY='D'; M=-11,-45, 22, 18,-20,-40, 9,-45,-22,-17,-36, 15,-17, 2, -8, 9, -9,-20,-47,-40; M0=-13; /I: MM=-1; MI=-44; MD=-53; IM=-13; II=-8; DM=-7; DD=-14; /M: SY='R'; M=-18,-44, -7,-23,-48,-18, 9,-45, 19,-45,-35, 4, -9, 9, 27, 8,-18,-41,-46,-39; M0=-17; /I: MM=-2; MI=-30; MD=-119; IM=-11; II=-9; DM=-3; DD=-23; /M: SY='I'; M= -4,-38,-34,-18,-39,-43, -8, 19, -3,-15, -6, 0,-43, 1, -9, -7, 18, 18,-41,-36; M0=-12; /I: MM=0; MI=-109; MD=-120; IM=-9; II=-11; DM=-7; DD=-14; /M: SY='I'; M=-65,-58,-89,-83, -6,-87,-74, 33,-81, 19, 4,-85,-77,-68,-76,-82,-63,-11,-58,-61; M0=-52; /I: MM=0; MI=-109; MD=-120; IM=-9; II=-11; DM=-7; DD=-14; /M: SY='S'; M=-16,-45,-18, 2,-48, 10,-11,-45, 9,-24,-36, 7,-41, 0, 4, 20, 7,-10,-47,-11; M0=-11; /I: MM=-24; MI=-109; MD=-3; IM=-9; II=-11; DM=-7; DD=-14; /M: SY='C'; M=-12, 20, 3,-21,-12, -5, 10, 4,-19, 19, -4, 6,-27,-16,-20,-17,-12, 3,-17,-13; M0=-7; /I: MM=0; MI=-85; MD=-96; IM=-9; II=-11; DM=-57; /M: SY='K'; M=-12,-27,-11, 7,-30,-22, -8,-28, 25,-27,-18, -8, -1, -4, 12, 10, 1,-23,-28,-22; M0=-9; /I: MM=-26; MI=-3; MD=-96; IM=-20; II=-4; DM=-57; /M: SY='K'; M=-15,-29,-14, 2,-33,-24, 16,-30, 26,-29,-20,-11, 17, -5, 8, 0,-14,-26,-30,-24; M0=-11; /I: MM=0; MI=-85; MD=-96; IM=-9; II=-11; DM=0; DD=-63; /M: SY='F'; M=-13,-38,-64,-60, 40, -6,-47,-37,-56, 7,-34,-51, -7,-51,-53,-22,-38,-10,-47,-43; M0=-28; /I: MM=0; MI=-109; MD=-120; IM=-9; II=-11; DM=-7; DD=-14; /M: SY='I'; M=-33, -7,-52,-46, 9,-48,-36, 25, 10,-30,-23,-15,-10, 0,-19,-21, 0, 19,-36, 3; M0=-16; /I: MM=0; MI=-109; MD=-120; IM=-9; II=-11; DM=-7; DD=-14; /M: SY='P'; M=-54,-73, 6,-34,-76,-51,-46,-76,-50,-74,-69, -4, 40,-11,-23,-14,-55,-70,-76,-65; M0=-42; /I: MM=0; MI=-109; MD=-120; IM=-9; II=-11; DM=-7; DD=-14; /M: SY='P'; M=-21,-42,-56,-53,-50,-26,-49,-46,-12, -1,-42, -8, 39,-49,-52,-14,-40, 1,-54,-51; M0=-27; /I: MM=0; MI=-109; MD=-120; IM=-9; II=-11; DM=-7; DD=-14; /M: SY='D'; M=-21,-46, 35, 0,-49,-41, -4,-47,-23,-15,-37, 13,-21, 3,-29,-13,-16,-32,-48,-41; M0=-19; /I: MM=0; MI=-109; MD=-120; IM=-9; II=-11; DM=-7; DD=-14; /M: SY='G'; M= -4,-45, -4, 1,-49, 31,-27,-46, 8,-45,-36, -5,-41, -4, -7,-10,-19,-42,-47,-40; M0=-18; /I: MM=-22; MI=-109; MD=-4; IM=-9; II=-11; DM=-7; DD=-14; /M: SY='C'; M= 1, 36,-22,-18,-36,-25,-20,-33,-17,-34,-26, 18, 22, 6,-22, 11,-18,-28,-37,-31; M0=-15; /I: MM=-8; MI=-88; MD=-13; IM=-9; II=-11; DM=-56; /M: SY='F'; M=-48,-40,-52,-55, 45,-46,-26,-41,-54,-34,-35,-46,-49,-47,-49,-49,-49,-43,-19, -8; M0=-41; /I: MM=0; MI=-80; MD=-90; IM=-9; II=-11; DM=-57; /M: SY='P'; M=-32,-35,-38,-35,-48,-35,-29,-49,-19,-46,-41,-33, 39,-27, 20,-33,-33,-43,-41,-42; M0=-30; /I: MM=-32; MI=-2; MD=-90; IM=-7; II=-14; DM=-57; /M: SY='N'; M=-11,-26, 15, -2,-29, 9, -7,-27, 6,-26,-17, 21,-21, 13, -9, 4,-10,-22,-28,-21; M0=-8; /I: MM=-32; MI=-2; MD=-90; IM=0; II=-56; DM=0; DD=-64; /M: SY='E'; M=-15,-45, 11, 22,-17,-24,-26,-17, 5,-45,-36, 12,-11, -9, 9, 7,-11,-14,-47, -8; M0=-10; /I: MM=0; MI=-109; MD=-120; IM=-9; II=-11; DM=-7; DD=-14; /M: SY='F'; M=-33, 0,-56,-50, 37,-48,-37,-11,-46, 4, -2,-45,-49,-19,-44,-19, -3, 9,-36, 9; M0=-23; /I: MM=0; MI=-109; MD=-120; IM=-9; II=-11; DM=-7; DD=-14; /M: SY='E'; M=-13, -3, -8, 19,-48, 13,-26,-45, -5,-45,-36, -8, -1, 6, 7,-29, 16, -3,-47,-40; M0=-13; /I: MM=0; MI=-109; MD=-120; IM=-9; II=-11; DM=-7; DD=-14; /M: SY='L'; M=-59,-53,-85,-80,-43,-84,-76, 1,-79, 30,-30,-80,-76,-71,-77,-78,-58, 16,-62,-63; M0=-52; /I: MM=0; MI=-109; MD=-120; IM=-9; II=-11; DM=-7; DD=-14; /M: SY='M'; M= -9, 22,-78,-72,-13,-73,-61,-19,-69, 19, 43,-70,-69,-61,-66,-65,-54, -9,-53,-53; M0=-41; /I: MM=0; MI=-109; MD=-120; IM=-9; II=-11; DM=-7; DD=-14; /M: SY='R'; M=-19,-45,-29, -1,-26,-21, 9,-46, 16,-45,-36, 5,-30, 12, 22, 15, -2,-41,-47,-12; M0=-15; /I: MM=0; MI=-109; MD=-120; IM=-9; II=-11; DM=-7; DD=-14; /M: SY='Y'; M=-76,-65,-79,-83, 12,-78,-40,-65,-79,-58,-59,-64,-77,-66,-72,-71,-74,-66, 42, 44; M0=-62; /I: MM=0; MI=-109; MD=-120; IM=-9; II=-11; DM=-7; DD=-14; /M: SY='R'; M=-18,-45,-29, -6,-15,-40, 18,-46, 7,-45,-36, -7,-41, 11, 32,-11, 3,-41,-47,-11; M0=-19; /I: MM=0; MI=-109; MD=-120; IM=-9; II=-11; DM=-7; DD=-14; /M: SY='I'; M= -1, 11,-18,-20,-16,-48,-37, 17, -3, 12, 10,-44,-49, -7,-43, -1, 5, 13,-36,-14; M0=-12; /I: MM=0; MI=-109; MD=-120; IM=-9; II=-11; DM=-7; DD=-14; /M: SY='N'; M= -4, -9, 6,-14,-48,-16, 2,-23, 4,-30,-11, 16,-17, 12, 2, 12, 8, 7,-47,-40; M0=-8; /I: MM=-61; MI=0; MD=-120; IM=0; II=-86; DM=-7; DD=-14; /M: SY='N'; M= -2,-45, 6, -2,-48, -5, 8, -6, -4, -4,-15, 16, 11, 14, -9, 3, -3,-10,-47,-40; M0=-5; /I: MM=-8; MI=-109; MD=-13; IM=-9; II=-11; DM=-7; DD=-14; /M: SY='N'; M= 6,-38, 10, 2,-41,-33,-20,-16, 9, 2,-29, 18, -3, 1, -8, -6, -2, 2,-40,-33; M0=-6; /I: MM=-8; MI=-13; MD=-43; IM=-18; II=-5; DM=-29; DD=-2; /M: SY='E'; M=-10,-25, 6, 17,-41,-14, 0,-24, 6, 3, -1, 13, 6, -3,-21, 3, -9,-10,-40,-33; M0=-6; /I: MM=0; MI=-102; MD=-112; IM=-9; II=-11; DM=0; DD=-49; /M: SY='V'; M=-19, -8, 4, -5, -4,-10,-28, 10, 4, -9, -8, -8,-42,-10, 8, 12,-10, 15,-44,-11; M0=-5; /I: MM=0; MI=-109; MD=-120; IM=-9; II=-11; DM=-9; DD=-11; /M: SY='N'; M= 6,-45,-14, 2,-16,-18, -5,-15, 14, -1,-11, 14, 6, 13, -6, -1, -6,-41,-47, 2; M0=-6; /I: MM=0; MI=-109; MD=-120; IM=-9; II=-11; DM=-9; DD=-11; /M: SY='P'; M= -5,-31,-53,-23,-13,-13,-36, 18,-21, 16,-23,-43, 20,-21,-24, -7, -7, 3,-36,-32; M0=-12; /I: MM=0; MI=-109; MD=-120; IM=-9; II=-11; DM=-9; DD=-11; /M: SY='P'; M=-20,-31,-19,-48,-31,-13,-37, -8,-45, 2, 5,-15, 38,-41,-43,-19,-32,-10,-36,-33; M0=-20; /I: MM=0; MI=-109; MD=-120; IM=-9; II=-11; DM=-9; DD=-11; /M: SY='F'; M=-37, -2,-60,-54, 27,-22,-42, 18,-50, 16, 1,-49,-53,-46,-48,-44,-16, 13,-40,-37; M0=-25; /I: MM=0; MI=-109; MD=-120; IM=-9; II=-11; DM=-9; DD=-11; /M: SY='W'; M=-19,-45,-15, -8,-48, -5, 9,-14, 11,-10,-36, 2,-41, 1, 9, 2, 14, -4, 24, 16; M0=-7; /I: MM=0; MI=-109; MD=-120; IM=-9; II=-11; DM=-9; DD=-11; /M: SY='V'; M=-33, 10,-56,-50, 11,-12,-37, 18,-23, 10, 3,-15,-49,-42,-44,-27,-16, 24,-36, -9; M0=-18; /I: MM=0; MI=-109; MD=-120; IM=-9; II=-11; DM=-9; DD=-11; /M: SY='N'; M=-30,-45, -1, 5, 4,-40, 7, 2, 12,-10,-35, 18,-41, -4, -4, 1, 7, 0,-46, 4; M0=-8; /I: MM=0; MI=-109; MD=-61; IM=-9; II=-11; DM=-9; DD=-11; /M: SY='C'; M= 8, 34, -9,-15,-12,-20, 10,-17,-13,-43,-34,-11, 19, -2,-27, 3, 9, -4,-46, -9; M0=-10; /I: MM=0; MI=-109; MD=-119; IM=-9; II=-11; DM=-14; DD=-7; /M: SY='W'; M=-14, -5,-16, -8, -9,-20,-21, 10, -6, -7, 2, 6,-18, 9,-32, 5, 2, -3, 42,-11; M0=-7; /I: MM=0; MI=-109; MD=-119; IM=-9; II=-11; DM=-5; DD=-17; /M: SY='V'; M= -9,-31,-14,-24, 3,-15,-36, 14,-18, 1, -6,-15, 15,-41,-20,-24, 1, 20, 5, 1; M0=-8; /I: MM=-3; MI=-109; MD=-23; IM=-9; II=-11; DM=-9; DD=-11; /M: SY='E'; M= -9, 13,-17, 16,-45,-37, -6,-10, 3,-12,-33, 8,-38, 4, 2, 15, 6,-13,-44, 6; M0=-8; /I: MM=-10; MI=-106; MD=-10; IM=-9; II=-11; DM=-38; DD=-1; /M: SY='M'; M= -8,-30, -3, 11, 10, -9, 1, -6,-12, -4, 15,-16, 12, 1, 8, 1,-14,-26, 12, 3; M0=-4; /I: MM=-11; MI=-9; MD=-106; IM=-22; II=-4; DM=0; DD=-59; /M: SY='S'; M=-30, 0, 4, 10,-48, 5,-11,-15, 9,-25,-36, 7,-19, 4, -8, 16, -2, -5, -5, -2; M0=-7; /I: MM=0; MI=-109; MD=-120; IM=-9; II=-11; DM=-7; DD=-14; /M: SY='H'; M= -7,-45,-10, 9,-27, 0, 17,-15, 9,-11, -8, 7, 1, -7,-15, 5, 2, 10,-47,-22; M0=-4; /I: MM=0; MI=-109; MD=-120; IM=-9; II=-11; DM=-7; DD=-14; /M: SY='S'; M= -7,-45, 1, -5,-48, 11, -5,-21, -4,-11, -7, 11, -6, 2, -9, 20, -1,-18,-47,-16; M0=-7; /I: MM=0; MI=-109; MD=-120; IM=-9; II=-11; DM=-7; DD=-14; /M: SY='G'; M= -6,-13, 7, 1,-48, 13, 12,-45, 0,-10,-36, 8,-11, 10, 9, 5, -4,-10, -4,-40; M0=-7; /I: MM=0; MI=-109; MD=-120; IM=-9; II=-11; DM=-7; DD=-14; /M: SY='N'; M= -4, 0, 12,-23,-48, 15, -3,-19, -4,-14,-36, 19,-41, -5,-15, 9, 10,-23,-46,-40; M0=-10; /I: MM=0; MI=-109; MD=-120; IM=-9; II=-11; DM=-7; DD=-14; /M: SY='R'; M= -5,-45,-15, 11,-15, 1, -8,-21, 15,-18,-36, -5,-16, -5, 25,-17, -4,-18,-16, -7; M0=-8; /I: MM=0; MI=-109; MD=-120; IM=-9; II=-11; DM=-7; DD=-14; /M: SY='F'; M=-10, 15,-56,-50, 24,-48,-37, 10,-46, 11, 7,-45,-49,-42,-44, -7,-10, 16,-36, 6; M0=-19; /I: MM=0; MI=-109; MD=-120; IM=-9; II=-11; DM=-7; DD=-14; /M: SY='E'; M=-30,-45, 16, 27,-48,-40,-26,-24, -7, -8,-36, 6,-41, 9,-10, -8, -3,-22,-47, 1; M0=-14; /I: MM=0; MI=-109; MD=-120; IM=-9; II=-11; DM=-7; DD=-14; /M: SY='V'; M=-33, 4,-18,-50, -3,-48,-37, 19,-46, 10, 1,-45,-49,-42,-17,-39,-15, 24,-36, 17; M0=-21; /I: MM=0; MI=-109; MD=-120; IM=-9; II=-11; DM=-7; DD=-14; /M: SY='M'; M=-23,-10,-18, -4, -9,-40, 8,-11, 11,-11, 17, 14,-41, 3, 13, -2, 14, -8,-46, -5; M0=-8; /I: MM=0; MI=-109; MD=-120; IM=-9; II=-11; DM=-7; DD=-14; /M: SY='I'; M= -4, 14,-56,-50, -2,-48,-37, 23,-46, 13,-23,-45,-49,-42,-31,-20,-32, 21,-36, -9; M0=-22; /I: MM=0; MI=-109; MD=-120; IM=-9; II=-11; DM=-7; DD=-14; /M: SY='E'; M=-20,-45,-12, 19, -4, 5, 5,-11, 15,-45,-36, 6,-41,-22, 2, -6, 9, -5, 1,-40; M0=-10; /I: MM=0; MI=-109; MD=-120; IM=-9; II=-11; DM=-7; DD=-14; /M: SY='Y'; M= 5,-31,-18,-50, -5,-48,-37, 18,-46, 12,-23, -2, -1,-42,-44,-18,-17, 7,-36, 26; M0=-15; /I: MM=0; MI=-109; MD=-120; IM=-9; II=-11; DM=-7; DD=-14; /M: SY='K'; M=-20,-45,-28, 16,-48,-12, 7,-45, 22,-15, 2, 4,-41, -7, 18, -7, 2,-41,-47,-40; M0=-14; /I: MM=-8; MI=-109; MD=-13; IM=-9; II=-11; DM=-7; DD=-14; /M: SY='M'; M= 4,-29,-31, -3,-29, -9,-24, -4,-24, 14, 23, -7,-38, 8, -2, 5, -5, 5,-33,-28; M0=-7; /I: MM=-1; MI=-101; MD=-35; IM=-9; II=-11; DM=-47; DD=-1; /M: SY='Q'; M= -6,-37, -4, 9,-40,-12,-18,-13, -5,-37,-28, 10, -6, 19,-19, 18, 10,-13,-39,-32; M0=-9; /I: MM=-31; MI=-17; MD=-8; IM=-54; II=0; DM=-4; DD=-22; /M: SY='C'; M= 9, 21, -6, 4,-42,-16,-20,-39,-16,-39,-29, 2, -4, -3, -7, 20, 12,-35,-40,-10; M0=-11; /I: MM=0; MI=-102; MD=-112; IM=-9; II=-11; DM=-23; DD=-3; /M: SY='N'; M=-13,-40, 14, -3,-43, 2, 10,-40,-11, -1, -2, 24,-36, 16, -6, -1,-16,-18,-41,-12; M0=-9; /I: MM=0; MI=-103; MD=-113; IM=-9; II=-11; DM=-44; DD=-1; /M: SY='F'; M= -9,-30,-33, -6, 32,-38, 0, 5, -2, -4,-22, 0,-11,-24,-11, -7,-11,-14,-34, 15; M0=-9; /I: MM=0; MI=-103; MD=-113; IM=-9; II=-11; DM=-11; DD=-9; /M: SY='K'; M=-11,-42, -4,-11,-45, -5, -6,-16, 20, -2,-33, -3, 18, -2, 7, 1, 3,-38,-44,-37; M0=-8; /I: MM=0; MI=-106; MD=-116; IM=-9; II=-11; DM=-1; DD=-39; /M: SY='S'; M= 1,-44,-12, 1,-16, 6, -9,-45, 6, -7, 6, -1, 10, -4, 1, 13, 1,-12,-46, -4; M0=-5; /I: MM=0; MI=-109; MD=-119; IM=-9; II=-11; DM=-9; DD=-11; /M: SY='K'; M=-30,-44, -2, 2,-48, 2,-26,-45, 18, -9, 0, 8,-15, 14, 12, -1, -8, 3,-46,-39; M0=-9; /I: MM=0; MI=-109; MD=-119; IM=-9; II=-11; DM=-9; DD=-11; /M: SY='M'; M=-18,-14, -4,-15, -2,-13,-28, 5, 10, 8, 11, 11, -9, 0, -6, 8,-16, -5, 1, -1; M0=-3; /I: MM=0; MI=-109; MD=-61; IM=-9; II=-11; DM=-9; DD=-11; /M: SY='T'; M= -7,-44, 0, 8, -6,-23, 10, -5, -6,-16,-35, -1, 1, 1,-12, 12, 18, 0,-46,-28; M0=-5; /I: MM=0; MI=-109; MD=-66; IM=-9; II=-11; DM=-14; DD=-7; /M: SY='C'; M= 20, 25,-56,-49, -4,-18,-36, 15,-45, 10, -2,-44,-18,-41,-43,-19, -6, 3,-35, 0; M0=-16; /I: MM=0; MI=-108; MD=-119; IM=-9; II=-11; DM=-3; DD=-24; /M: SY='E'; M=-14, -4, 3, 21,-48,-39, -4,-15, 7,-14,-35, 17,-40, 10,-14, -2, 8,-41,-46, -3; M0=-12; /I: MM=0; MI=-109; MD=-119; IM=-9; II=-11; DM=-7; DD=-14; /M: SY='N'; M=-27,-18, 22, -7, 0, -6, -4,-45, 2,-45,-12, 30,-41, -2,-27, -9,-14,-17,-46,-15; M0=-15; /I: MM=0; MI=-109; MD=-119; IM=-9; II=-11; DM=-7; DD=-14; /M: SY='V'; M=-53, 13,-80,-76,-50,-78,-77, 17,-76, 13, 6,-75,-75,-73,-77,-72,-53, 29,-68,-65; M0=-47; /I: MM=0; MI=-109; MD=-119; IM=-9; II=-11; DM=-7; DD=-14; /M: SY='E'; M= -8, 3, -4, 13,-10,-40,-16, 0, 6, -2, 3, 1,-41, -8, 5, -3, 8, 12,-45,-39; M0=-6; /I: MM=0; MI=-109; MD=-119; IM=-9; II=-11; DM=-7; DD=-14; /M: SY='I'; M=-10,-41,-69,-64, 6,-63,-54, 29,-61, -1, 2,-22,-62,-57,-59,-55,-44, 23,-51,-48; M0=-33; /I: MM=0; MI=-109; MD=-119; IM=-9; II=-11; DM=-7; DD=-14; /M: SY='H'; M=-18,-44,-11, -2,-23,-24, 19, 1, 14, -5, -4, 0,-41, 3, 8, 3, 13, -3,-46, -2; M0=-6; /I: MM=0; MI=-109; MD=-119; IM=-9; II=-11; DM=-7; DD=-14; /M: SY='I'; M=-33, 1,-57,-50, 9,-38,-38, 31,-46, 4, 6,-45,-49,-43,-44,-28,-33, 17,-36, -9; M0=-24; /I: MM=0; MI=-109; MD=-119; IM=-9; II=-11; DM=-7; DD=-14; /M: SY='P'; M=-31,-16,-33,-15,-14,-42, 5,-37,-26,-39, 1,-11, 38, -2, -9,-31, -9,-34,-42, -2; M0=-21; /I: MM=0; MI=-109; MD=-119; IM=-9; II=-11; DM=-7; DD=-14; /M: SY='V'; M=-21, 12,-56,-50, 12,-21,-37, 11,-46, 15, 15,-45,-49,-42,-44,-39, 1, 22,-35, -9; M0=-20; /I: MM=0; MI=-109; MD=-119; IM=-9; II=-11; DM=-7; DD=-14; /M: SY='P'; M=-14, 0,-17,-30, -2,-12, 4,-33,-18,-35, -5, 3, 36,-28,-33,-15,-10,-17,-40, 8; M0=-15; /I: MM=-1; MI=-109; MD=-39; IM=-9; II=-11; DM=-7; DD=-14; /M: SY='K'; M= -2,-44, -4, 2,-47,-39, 3,-44, 15,-12, 5, 6, 11, -2, 8, 11, 5,-19,-46,-39; M0=-9; /I: MM=-3; MI=-108; MD=-23; IM=-9; II=-11; DM=-25; DD=-3; /M: SY='D'; M= -4, 4, 16, 6, -8, 7, 8,-16,-18,-41,-32, 16,-13, 10, 2, -4,-13, 1,-43,-36; M0=-7; /I: MM=-11; MI=-105; MD=-9; IM=-9; II=-11; DM=-41; DD=-1; /M: SY='W'; M= -8,-28, -3, -2, 14, 0, 8, 3,-12,-11,-19, 7, -4,-11,-16, 4, 7,-23, 35,-25; M0=-5; /I: MM=-17; MI=-5; MD=-104; IM=-41; II=-1; DM=-15; DD=-6; /M: SY='V'; M= 2, 10,-13,-40, 11,-40,-29, -6,-12, 9,-16,-36, -1, 1,-35, 3, 11, 13,-28, 6; M0=-8; /I: MM=0; MI=-100; MD=-111; IM=-9; II=-11; DM=-6; DD=-16; /M: SY='V'; M= 11,-39,-16, 3, -4,-10, 0, 8,-13,-19,-30,-11,-39,-22, -1, 6, 13, 13,-41, -9; M0=-6; /I: MM=0; MI=-107; MD=-117; IM=-9; II=-11; DM=-23; DD=-3; /M: SY='D'; M= -1,-42, 11, -3,-10, -9, -4, 6, 8, -2, -2, 6,-39, -2,-11, 8, 2, 2,-44,-26; M0=-4; /I: MM=0; MI=-107; MD=-117; IM=-9; II=-11; DM=-5; DD=-19; /M: SY='S'; M= 3,-44, 2, 0,-47, -9, 11, -1, 6,-17,-35, 5, -1, -5, -7, 17, 0, 0,-46,-39; M0=-6; /I: MM=0; MI=-108; MD=-119; IM=-9; II=-11; DM=-3; DD=-25; /M: SY='P'; M= 3, 15, -8, -9,-47,-40, -9, -5, 6, -6, 4,-13, 25, 5, -1, -3, -7, 2,-46,-39; M0=-7; /I: MM=0; MI=-109; MD=-119; IM=-9; II=-11; DM=-7; DD=-14; /M: SY='N'; M=-18,-44, 4, 7,-48,-26,-11, -2, 11,-10,-35, 15, -8, -2, 3, 8, 0, 7,-46,-15; M0=-6; /I: MM=0; MI=-109; MD=-119; IM=-9; II=-11; DM=-7; DD=-14; /M: SY='F'; M=-12,-31,-55,-15, 21,-30, -6, 16,-13, 11, 4,-44, -4, -7,-37, 0,-20, 10,-35, 3; M0=-11; /I: MM=0; MI=-109; MD=-119; IM=-9; II=-11; DM=-7; DD=-14; /M: SY='R'; M=-12,-44,-10, 1,-48, -1, 4, -4, 12,-45,-35, 13,-40, 13, 16, -2, 10, -8,-46, -8; M0=-10; /I: MM=0; MI=-109; MD=-119; IM=-9; II=-11; DM=-7; DD=-14; /M: SY='C'; M= 6, 21, -1, 3,-44,-40,-27, 5,-11,-10,-33, -1, -8, 1,-28, 5, 11, 13,-45, -6; M0=-7; /I: MM=0; MI=-109; MD=-119; IM=-9; II=-11; DM=-7; DD=-14; /M: SY='S'; M= -4, 12, 0, -1,-13,-31,-27, -5,-24,-19, -5, 5, -8, -6, -6, 19, 18,-12,-44,-11; M0=-7; /I: MM=0; MI=-109; MD=-119; IM=-9; II=-11; DM=-7; DD=-14; /M: SY='H'; M= -4, -6, 16, -5,-13,-23, 24, 7, -5, -4,-19, 12,-23, 6, -6, 2,-14, -8,-46, -9; M0=-5; /I: MM=0; MI=-109; MD=-119; IM=-9; II=-11; DM=-7; DD=-14; /M: SY='G'; M= -8,-48,-16,-30, -4, 35,-34,-52,-16,-52,-43,-32,-17, 2,-36,-12,-16,-47,-54,-47; M0=-24; /I: MM=0; MI=-109; MD=-119; IM=-9; II=-11; DM=-7; DD=-14; /M: SY='K'; M=-11, -6, 8, 7,-48,-12, 1,-11, 16,-45,-35, 10,-40, 5, 0, 9, 13,-41,-46,-39; M0=-12; /I: MM=0; MI=-109; MD=-119; IM=-9; II=-11; DM=-7; DD=-14; /M: SY='Y'; M= 17, 16,-56,-49, 1,-13,-21, 6,-45, -3, -3,-44,-15, -6,-43,-23, -7, 15, 16, 20; M0=-14; /I: MM=0; MI=-109; MD=-119; IM=-9; II=-11; DM=-7; DD=-14; /M: SY='K'; M=-18,-44, -9, 16,-48, -2, 0,-11, 22,-45, -9, 7,-40, -5, 4, -5, 2, 0,-46,-39; M0=-11; /I: MM=0; MI=-109; MD=-119; IM=-9; II=-11; DM=-7; DD=-14; /M: SY='Y'; M= -7,-31,-56,-49, 21,-48, 10, 1,-45, -6, -8, -2,-48,-12,-43,-20, -9,-13, 16, 37; M0=-19; /I: MM=0; MI=-109; MD=-119; IM=-9; II=-11; DM=-7; DD=-14; /M: SY='D'; M= -4, -2, 20, 10,-13,-18, 3, 5, 4,-15, 11, 13,-40, -6, -4,-12,-17, -4,-46,-24; M0=-6; /I: MM=0; MI=-109; MD=-50; IM=-9; II=-11; DM=-7; DD=-14; /M: SY='P'; M= -1,-44, 1, -8,-47,-23, 14, 0, -1, -9, -6, -9, 24, 2, -6, 9, 0,-11,-46,-39; M0=-7; /I: MM=-2; MI=-33; MD=-119; IM=-16; II=-6; DM=-3; DD=-25; /M: SY='E'; M= 1,-44, 4, 16,-15, -1, 6, -9, -3,-25,-35, -3,-40, -2, 7, 9, 7, -2,-46,-39; M0=-7; /I: MM=0; MI=-109; MD=-119; IM=-9; II=-11; DM=-7; DD=-14; /M: SY='E'; M=-14,-44, 5, 17,-14, 0, 6,-22, 14,-35, -7, 7,-40, 1, 6, 1, 0,-26,-46, 0; M0=-8; /I: MM=0; MI=-109; MD=-119; IM=-9; II=-11; DM=-7; DD=-14; /M: SY='N'; M=-15,-44, 9,-14,-48, 4, 8,-20, 13,-45, -8, 25,-40, 8, 5, 4,-29,-12,-46,-11; M0=-12; /I: MM=0; MI=-109; MD=-119; IM=-9; II=-11; DM=-7; DD=-14; /M: SY='C'; M= 14, 17,-49,-10, -2, 1, -5, 2, -9, 1, 8,-41,-47, -3, -5, 4, -5, 9,-36, -5; M0=-7; /I: MM=0; MI=-109; MD=-119; IM=-9; II=-11; DM=-7; DD=-14; /M: SY='I'; M=-21, 2,-56,-50,-23, -3,-37, 22,-45, 22, 9,-44,-48,-29,-43,-20,-17, 8,-35,-32; M0=-20; /I: MM=0; MI=-109; MD=-119; IM=-9; II=-11; DM=-7; DD=-14; /M: SY='V'; M=-12,-36,-37, 14, -2,-43,-10, 8, -8, 3,-13, -2,-31, -3, -4,-12, -5, 21,-40, -1; M0=-8; /I: MM=0; MI=-109; MD=-119; IM=-9; II=-11; DM=-7; DD=-14; /M: SY='W'; M=-67,-59,-82,-82,-11,-80,-48, -5,-79,-29,-36,-70,-76,-67,-73,-73,-65,-21, 62,-29; M0=-55; /I: MM=0; MI=-109; MD=-119; IM=-9; II=-11; DM=-7; DD=-14; /M: SY='K'; M=-13, -1, 4, -6,-12,-39, 7, 0, 20,-44,-35, 11,-40,-17, 9, 9, 5,-13,-46, -2; M0=-10; /I: MM=0; MI=-109; MD=-119; IM=-9; II=-11; DM=-7; DD=-14; /M: SY='I'; M=-21, 1,-63,-57, 8,-56,-45, 33,-53, 7, -7,-52,-56,-50,-52,-47,-39, 10,-43,-14; M0=-30; /I: MM=0; MI=-109; MD=-119; IM=-9; II=-11; DM=-7; DD=-14; /M: SY='P'; M=-19,-44, 15, -3,-48, 13, -7,-27, 15,-14,-35, 8, 17, -3, 2, -8,-29,-41,-46,-39; M0=-11; /I: MM=0; MI=-109; MD=-119; IM=-9; II=-11; DM=-7; DD=-14; /M: SY='K'; M=-30,-44,-28, -5,-48,-18,-26,-13, 22,-18,-35, 6,-18, 8, 18, 7, 2, 1,-46, -8; M0=-10; /I: MM=0; MI=-109; MD=-119; IM=-9; II=-11; DM=-7; DD=-14; /M: SY='I'; M=-20, 4,-56,-21, 21,-48,-37, 23, -6, 10, 5,-16,-48,-14,-43,-11,-13, 5,-35, -1; M0=-14; /I: MM=0; MI=-109; MD=-119; IM=-9; II=-11; DM=-7; DD=-14; /M: SY='P'; M= -1,-44, 13, -6, -2,-11, 2,-32, 6,-21, -7, 4, 21, 3, -9, -5, 6, -2,-46,-28; M0=-6; /I: MM=0; MI=-109; MD=-119; IM=-9; II=-11; DM=-7; DD=-14; /M: SY='G'; M= 2,-44, 0, -5,-48, 24,-26,-45, -1,-17,-22, 4, 6, -8, -6, -1,-10, -5, 1,-39; M0=-9; /I: MM=0; MI=-109; MD=-119; IM=-9; II=-11; DM=-7; DD=-14; /M: SY='G'; M= -5, -3, 3, 0,-48, 18, -8,-45, 12,-13, 10, 5,-29, 6,-27, 6, 0,-15,-46,-39; M0=-9; /I: MM=0; MI=-109; MD=-119; IM=-9; II=-11; DM=-7; DD=-14; /M: SY='N'; M=-10, -5,-15,-23,-47, 7, 11,-20, 16,-18, -8, 21,-40, 4, -5, 6, 10,-21,-46,-39; M0=-10; /I: MM=0; MI=-109; MD=-119; IM=-9; II=-11; DM=-7; DD=-14; /M: SY='E'; M= -8, -4, -8, 19,-15, -4, 0,-13, 1,-12, 1, -6, -2, 10, -6, 9, 9,-41,-46,-39; M0=-6; /I: MM=0; MI=-109; MD=-119; IM=-9; II=-11; DM=-7; DD=-14; /M: SY='H'; M= 0, 9,-17, -4, 9, -1, 15,-22,-20, -8, 3, 5, 6, 5,-29, 12, 2,-11,-44, 9; M0=-4; /I: MM=0; MI=-109; MD=-119; IM=-9; II=-11; DM=-7; DD=-14; /M: SY='G'; M= 1, -8,-18,-26, -6, 11, -5, 3, 0, -7, 10, -5, 2, 3,-16, 9, 10, -4,-42,-37; M0=-4; /I: MM=-8; MI=-109; MD=-13; IM=-9; II=-11; DM=-7; DD=-14; /M: SY='S'; M= 4, 9, -6,-30, 1, -8,-26, 1,-11, 1,-18,-11,-39, -6,-11, 15, -4, 11,-30, 14; M0=-5; /I: MM=-8; MI=-101; MD=-13; IM=-9; II=-11; DM=-47; DD=-1; /M: SY='H'; M= -4,-24,-21,-15, -3,-29, 24, -8, 3, 15, 11, -3, -4, 1, -5, 0, -4,-19,-27, 0; M0=-5; /I: MM=-2; MI=-93; MD=-27; IM=-9; II=-11; DM=-53; /M: SY='E'; M=-15,-28,-14, 19, 9, 1, 11, -9, 0,-27,-19,-12, 10, -7, 2, -3, 6, -6, 6,-24; M0=-5; /I: MM=-14; MI=-7; MD=-101; IM=-29; II=-2; DM=-54; /M: SY='H'; M= 14, 13, 15,-15,-21,-28, 31, 2,-14,-20, -2, 3,-28, 3,-17,-17,-15, -4, 7,-20; M0=-9; /I: MM=0; MI=-91; MD=-101; IM=-9; II=-11; DM=-41; DD=-1; /M: SY='C'; M=-16, 24, -1,-15, 17, -7, 6, -2,-13, -2,-14, 1, 3, 10,-17, 1, 10,-18,-26, -2; M0=-4; /I: MM=0; MI=-92; MD=-102; IM=-9; II=-11; DM=-7; DD=-14; /M: SY='M'; M= -4,-27,-52,-20, 19,-44,-33, 8,-42, 21, 30,-41,-45,-38,-40,-17,-22,-17,-32,-28; M0=-20; /I: MM=0; MI=-105; MD=-115; IM=-9; II=-11; DM=-10; DD=-10; /M: SY='S'; M= -3,-42,-26,-11, -7,-38,-10,-43, 11,-22, -5, -5, 9, -6, 16, 18, 1, -8,-44, -3; M0=-9; /I: MM=0; MI=-107; MD=-117; IM=-9; II=-11; DM=-14; DD=-7; /M: SY='G'; M= 17, 13,-18,-47, 3, 18,-35, 4,-18, 0, 11,-14,-47,-40,-24, -3,-19, -5,-34, -4; M0=-10; /I: MM=0; MI=-107; MD=-118; IM=-9; II=-11; DM=-1; DD=-34; /M: SY='E'; M= -6, 15, -6, 24,-48,-39, 11,-36, 2,-23,-15, -3,-30, 5, -4, 7, 11,-41,-46,-16; M0=-12; /I: MM=0; MI=-109; MD=-119; IM=-9; II=-11; DM=-7; DD=-14; /M: SY='F'; M=-14,-31,-56,-50, 25,-48,-37, 11,-34, 11, 14,-44,-17,-27,-43,-39,-32, 21,-35, -1; M0=-21; /I: MM=0; MI=-109; MD=-119; IM=-9; II=-11; DM=-7; DD=-14; /M: SY='E'; M= -2,-44,-21, 19,-48, 6, 12,-45, -6,-26,-20, -2,-10, 5, -5, 12, 11,-17,-46,-39; M0=-10; /I: MM=0; MI=-109; MD=-119; IM=-9; II=-11; DM=-7; DD=-14; /M: SY='L'; M=-19, -5,-20,-49, 21,-12,-37, 7,-45, 22,-23,-16,-48,-42,-17,-17,-32, 10,-35,-10; M0=-16; /I: MM=0; MI=-109; MD=-119; IM=-9; II=-11; DM=-7; DD=-14; /M: SY='P'; M= -3,-44, -8, 6,-10, -1,-26, -5, -6,-15,-12,-12, 22, 8,-12, 8, 5, -9,-46,-13; M0=-5; /I: MM=0; MI=-109; MD=-119; IM=-9; II=-11; DM=-7; DD=-14; /M: SY='S'; M= 8, -3, -9, -3,-47,-17, -8,-24,-17,-44,-35, 15, 8, -6, -9, 23, -3,-24,-46,-12; M0=-11; /I: MM=0; MI=-109; MD=-119; IM=-9; II=-11; DM=-7; DD=-14; /M: SY='E'; M= -7, -2, 3, 12,-12, 3, 1, -7, 7,-11,-12, -5,-17, 0,-12, 8, 8, 3,-46,-21; M0=-3; /I: MM=0; MI=-109; MD=-119; IM=-9; II=-11; DM=-7; DD=-14; /M: SY='D'; M= 0,-24, 17, -3,-10, -2, 3,-23, -6,-11, 1, 10, -3, 5, 2, 5, 6,-15, -9,-17; M0=-3; /I: MM=-1; MI=-109; MD=-34; IM=-9; II=-11; DM=-7; DD=-14; /M: SY='E'; M= 0,-38, 8, 15,-46,-10, 14,-44, -5,-17,-34, 14, 9, 6,-16, 10, -8,-32,-45,-12; M0=-9; /I: MM=-3; MI=-107; MD=-22; IM=-9; II=-11; DM=-28; DD=-2; /M: SY='H'; M=-10,-40, 15, 7, 4,-11, 17, 0, 2,-14,-31, 2, -3, 1, -7, 0, -1,-25,-42, 14; M0=-4; /I: MM=-32; MI=-5; MD=-24; IM=-38; II=-1; DM=-18; DD=-5; /M: SY='I'; M= -1, 4,-18, 3, 3,-30, -3, 13, 5, 9, 5, 5,-15, 1,-19,-10, 3, -2,-37,-32; M0=-4; /I: MM=0; MI=-103; MD=-113; IM=-9; II=-11; DM=-10; DD=-10; /M: SY='C'; M= 0, 15, 8, -9,-13,-29,-11,-23, 14, -4,-23, -6, 12, 11, 1, 1, -2,-13,-43, 1; M0=-5; /I: MM=0; MI=-106; MD=-116; IM=-9; II=-11; DM=-16; DD=-6; /M: SY='P'; M= -2,-42,-17, 5,-45,-38, -8, 2, 4,-10, 4, -3, 19, 0, -2, 4, 4, 4, 5, -9; M0=-5; /I: MM=0; MI=-107; MD=-117; IM=-9; II=-11; DM=-20; DD=-4; /M: SY='W'; M= -6, -2, 4, 9,-23, -8, 6,-28, 1, 2,-34, 3,-18, 8, -2, -4, 0, -6, 34,-17; M0=-4; /I: MM=0; MI=-107; MD=-117; IM=-9; II=-11; DM=-1; DD=-36; /M: SY='E'; M= 8,-44, 4, 11, 4, -9, -7,-45, 5, -9, -8, 4,-19, -4, -7, 8, 2, -9, 6, -5; M0=-4; /I: MM=0; MI=-109; MD=-119; IM=-9; II=-11; DM=-7; DD=-14; /M: SY='F'; M= -6,-39,-14,-27, 15,-21,-28,-10, 13, 8,-30, 9, -3,-15, 11,-19, -3, 5,-42, 0; M0=-6; /I: MM=0; MI=-109; MD=-119; IM=-9; II=-11; DM=-7; DD=-14; /M: SY='P'; M= -1,-44, -7,-10, 18, 3,-26,-14, -4,-28, 1, 1, 24, -2, 4, -2,-11,-14,-46,-12; M0=-7; /I: MM=0; MI=-109; MD=-119; IM=-9; II=-11; DM=-7; DD=-14; /M: SY='P'; M=-30,-37,-34,-16, -2,-23, 15,-25,-21, -7,-29,-27, 32, 0,-16, 3, -2, -9,-40, 11; M0=-12; /I: MM=0; MI=-109; MD=-119; IM=-9; II=-11; DM=-7; DD=-14; /M: SY='I'; M= 7, -3,-32,-49, -2,-48,-36, 24,-30, 5, 16,-44,-48,-41,-43,-22,-32, 20,-35,-10; M0=-19; /I: MM=0; MI=-109; MD=-119; IM=-9; II=-11; DM=-7; DD=-14; /M: SY='S'; M= -2,-44, 2, 1,-26,-20, -5,-45, 9,-25, -8, 13,-19, 10, -2, 17, 3,-19,-46, 4; M0=-8; /I: MM=0; MI=-109; MD=-119; IM=-9; II=-11; DM=-7; DD=-14; /M: SY='M'; M= -9, 7,-13,-50,-30,-16,-37, 10,-46, 13, 27,-45,-49,-42,-44,-24,-32, 24,-35,-32; M0=-20; /I: MM=0; MI=-109; MD=-119; IM=-9; II=-11; DM=-7; DD=-14; /M: SY='K'; M=-19,-44, 9, 12,-18, -1, -2,-45, 13,-29,-35, 9,-40, 12, -3, 13, -5,-21,-46,-11; M0=-10; /I: MM=0; MI=-109; MD=-119; IM=-9; II=-11; DM=-7; DD=-14; /M: SY='F'; M=-14, -9,-55,-49, 40,-48,-36,-26,-20, -3,-23,-44,-48,-41,-18,-11,-17,-25,-35, 18; M0=-23; /I: MM=0; MI=-109; MD=-119; IM=-9; II=-11; DM=-7; DD=-14; /M: SY='E'; M= -4,-44, -8, 19,-47,-39,-26,-45, 15,-44,-35, -6,-11, 8, -5, 15, 7,-17,-46,-39; M0=-14; /I: MM=0; MI=-109; MD=-119; IM=-9; II=-11; DM=-7; DD=-14; /M: SY='I'; M= -8,-30,-55,-21,-30,-23, 12, 30,-19, 1, 12,-44,-48,-41,-43,-10,-32, 13,-35, -1; M0=-17; /I: MM=0; MI=-109; MD=-119; IM=-9; II=-11; DM=-7; DD=-14; /M: SY='P'; M=-22,-44, -7,-14,-47,-39,-26,-19, 5,-14, 9, 8, 29, 9,-13, 1, 3, -7,-46,-39; M0=-11; /I: MM=-1; MI=-109; MD=-36; IM=-9; II=-11; DM=-7; DD=-14; /M: SY='M'; M= -8,-43, 4,-13, -1, 10, -4,-44, -6,-24, 29, -5,-39, 10, -8, -9, -3,-39,-45, 26; M0=-11; /I: MM=-3; MI=-26; MD=-118; IM=-15; II=-6; DM=-1; DD=-34; /M: SY='F'; M= -3, 10,-20,-46, 26, -7, 11, -2,-11, 0,-13,-23,-48, 3,-42, 2, 2, -9, 11, 17; M0=-9; /I: MM=0; MI=-109; MD=-119; IM=-9; II=-11; DM=-7; DD=-14; /M: SY='T'; M= 7, 2,-14,-24,-44,-40, -4,-33,-13,-11,-33, -2,-15, -4,-28, 17, 26, -9,-45,-38; M0=-13; /I: MM=0; MI=-109; MD=-119; IM=-9; II=-11; DM=-7; DD=-14; /M: SY='C'; M= 7, 22,-55, -7, 5,-20,-36, 8,-45, 2, -9, -7, 6,-41,-43, -2, 7, 13,-35, 1; M0=-10; /I: MM=0; MI=-109; MD=-119; IM=-9; II=-11; DM=-7; DD=-14; /M: SY='S'; M=-20, 4,-34,-17,-48,-20, -5,-44,-27,-45,-37, -1,-44,-27,-23, 33, 7,-19,-48,-42; M0=-22; /I: MM=0; MI=-108; MD=-119; IM=-9; II=-11; DM=-7; DD=-14; /M: SY='G'; M=-16,-44, -3,-12,-47, 30, -6,-23, 1,-24, -8, 3,-40,-21, 1,-10, -6,-14,-46,-39; M0=-13; /I: MM=0; MI=-108; MD=-119; IM=-9; II=-11; DM=-7; DD=-14; /M: SY='L'; M=-17, 7,-55,-49, 10,-21, -4, 17,-18, 22, 14,-44,-20,-41,-43,-38, -2, 0,-35,-31; M0=-17; /I: MM=0; MI=-108; MD=-119; IM=-9; II=-11; DM=-7; DD=-14; /M: SY='K'; M=-14,-44,-13, -2,-11,-13, -8,-45, 23,-19,-35,-10,-27, 22, 4, -5, -4, 1,-46, 9; M0=-9; /I: MM=0; MI=-108; MD=-119; IM=-9; II=-11; DM=-7; DD=-14; /M: SY='V'; M=-13,-44,-76,-72,-51,-72,-70, 20,-71,-11,-39,-69,-71,-70,-72,-16,-23, 33,-66,-61; M0=-40; /I: MM=0; MI=-108; MD=-119; IM=-9; II=-11; DM=-7; DD=-14; /M: SY='R'; M=-14,-44, 17, 14,-47,-39,-16,-45, -1,-24,-35, 2,-40, 8, 26,-17, -4,-22,-46, -4; M0=-14; /I: MM=0; MI=-108; MD=-118; IM=-9; II=-11; DM=-7; DD=-14; /M: SY='Y'; M=-13,-43,-14,-22, 10,-17, -7,-20, 12,-43,-34,-11,-40, 4, 1, 15, -3,-19, -4, 30; M0=-12; /I: MM=0; MI=-108; MD=-118; IM=-9; II=-11; DM=-7; DD=-14; /M: SY='L'; M=-32, 0,-55,-21, 0,-32, -3, 13,-17, 23, -1,-44,-48,-16,-43,-14,-31, 11,-34, 5; M0=-16; /I: MM=0; MI=-108; MD=-118; IM=-9; II=-11; DM=-7; DD=-14; /M: SY='K'; M= -7,-44, 11, 8,-14,-15,-25,-17, 23,-30, -7, -4,-40, -1, 10, 2, -3, -6,-45,-39; M0=-9; /I: MM=0; MI=-108; MD=-118; IM=-9; II=-11; DM=-7; DD=-14; /M: SY='V'; M=-32, 3,-55,-49,-30,-48,-36, 23,-45, 2, 21,-44, -9,-18,-43, -8, -9, 24,-35,-31; M0=-21; /I: MM=0; MI=-108; MD=-118; IM=-9; II=-11; DM=-7; DD=-14; /M: SY='V'; M= 1,-39, 1, 6, 3,-40,-27, 1, -6, 4,-31, 3,-20, 11,-29, 1,-15, 12, 8, 9; M0=-6; /I: MM=-1; MI=-107; MD=-43; IM=-9; II=-11; DM=-7; DD=-14; /M: SY='E'; M= -6,-42, 3, 24, -9, 4,-24,-15, 3,-42,-33, 10, -9, -8, -4, -2, -2,-10,-44,-37; M0=-9; /I: MM=-1; MI=-106; MD=-48; IM=-9; II=-11; DM=-21; DD=-4; /M: SY='K'; M= -4,-42, 7, 9, -4, -6, 6,-43, 17,-14,-33, 0, 15, -8, -3, 3,-16,-38,-44, -6; M0=-8; /I: MM=-3; MI=-106; MD=-25; IM=-9; II=-11; DM=-26; DD=-3; /M: SY='K'; M= -4,-39, -2, 7,-43, -3, 0,-40, 18,-12,-30, -3, 10, 15, 3, 2, -3,-36,-41,-12; M0=-8; /I: MM=-10; MI=-21; MD=-20; IM=-15; II=-6; DM=-2; DD=-31; /M: SY='S'; M= 0,-40, 8, 5,-43, -5,-22, -9, -1, 6, 1,-12, -6,-17,-23, 21, -5,-36,-41,-35; M0=-8; /I: MM=0; MI=-104; MD=-114; IM=-9; II=-11; DM=-10; DD=-10; /M: SY='N'; M=-17,-41, 11, 5,-45, 8, -4,-42, 1,-42,-32, 21, 7, 15,-14,-10, 9,-38,-43,-36; M0=-13; /I: MM=0; MI=-105; MD=-116; IM=-9; II=-11; DM=-5; DD=-19; /M: SY='Y'; M=-13,-42,-13, 3,-16,-15, 6,-18, 6,-22,-33, -5, -4,-20,-11, -2, -7, 5,-44, 36; M0=-9; /I: MM=0; MI=-107; MD=-117; IM=-9; II=-11; DM=-3; DD=-23; /M: SY='K'; M=-19,-43, 4, 3,-46,-38,-12,-17, 20, -7,-34, 9, 2, 19, 9, 1, -6,-24,-45,-38; M0=-10; /I: MM=0; MI=-107; MD=-118; IM=-9; II=-11; DM=-7; DD=-14; /M: SY='P'; M= 3, -1,-53,-47, 2,-25,-35, 6, -9, -7,-21,-26, 28,-40,-42, 11, 2, 2,-34,-30; M0=-13; /I: MM=0; MI=-107; MD=-118; IM=-9; II=-11; DM=-7; DD=-14; /M: SY='Y'; M=-30,-31,-21, -2, 23,-44, 11, 9,-13, 0,-11,-36,-45, 1, -6,-10,-19, 9,-36, 24; M0=-11; /I: MM=0; MI=-107; MD=-117; IM=-9; II=-11; DM=-7; DD=-14; /M: SY='K'; M=-18,-43, -6, -1,-29,-38,-24,-43, 30,-43,-34,-24, 18, 3, 4, -7,-16,-11,-45,-38; M0=-16; /I: MM=0; MI=-107; MD=-117; IM=-9; II=-11; DM=-7; DD=-14; /M: SY='W'; M= -9,-42,-12,-11, 3, 18, 1,-42,-12,-42,-33,-11,-10,-20, -6,-27, -7,-19, 50,-12; M0=-15; /I: MM=0; MI=-107; MD=-117; IM=-9; II=-11; DM=-7; DD=-14; /M: SY='V'; M=-13, 10,-18,-48, -5,-46, -9, 14,-29,-19,-21,-22,-47,-40,-42,-11, -4, 32,-34,-15; M0=-18; /I: MM=0; MI=-107; MD=-117; IM=-9; II=-11; DM=-7; DD=-14; /M: SY='R'; M=-16, -4,-31,-25,-50,-42,-14,-47, 21,-21,-37,-10,-42, -8, 32,-18, 6,-43,-47,-41; M0=-21; /I: MM=-1; MI=-107; MD=-36; IM=-9; II=-11; DM=-7; DD=-14; /M: SY='Y'; M=-13, -5,-35,-16,-13,-42, 13,-31, -2,-13,-27,-31,-43, -7,-11,-32,-29,-30,-38, 44; M0=-20; /I: MM=-2; MI=-34; MD=-47; IM=-10; II=-10; DM=-9; DD=-11; /M: SY='I'; M=-10,-28,-53,-46,-20,-45, -3, 21, 1, 10, 8,-41,-46, -8,-40, 7, 0, 15,-33,-29; M0=-15; /I: MM=0; MI=-106; MD=-116; IM=-9; II=-11; DM=-6; DD=-16; /M: SY='T'; M= 3, -5,-53,-47,-28,-14,-35, -1,-43,-12, -6,-15,-46,-39,-41, 7, 33, -5,-33,-30; M0=-19; /I: MM=0; MI=-107; MD=-117; IM=-9; II=-11; DM=-4; DD=-22; /M: SY='Q'; M=-21,-43, 0, -2,-46,-38, 14, -4, 18,-20, -9,-12,-39, 23, 9, 3, -4, -7,-45, -4; M0=-10; /I: MM=0; MI=-107; MD=-117; IM=-9; II=-11; DM=-7; DD=-14; /M: SY='S'; M= 17,-42, -5,-21,-12,-22, 3,-43,-11,-42,-33, 13,-16,-20, -7, 19, 6,-17,-44, 5; M0=-12; /I: MM=-1; MI=-107; MD=-38; IM=-9; II=-11; DM=-7; DD=-14; /M: SY='G'; M= -6,-48, 16, -7,-51, 29,-28,-49, -5,-48,-39, 11,-42, -9,-30,-13,-32,-17,-50,-42; M0=-19; /I: MM=-3; MI=-26; MD=-48; IM=-11; II=-9; DM=-7; DD=-14; /M: SY='S'; M= 2, 4, 14, 9,-45,-18, -2,-15, 8,-23, -3, 7,-38, -1, -6, 14, -3,-23,-44, 0; M0=-7; /I: MM=0; MI=-106; MD=-116; IM=-9; II=-11; DM=-2; DD=-29; /M: SY='Y'; M=-41, -5,-62,-57, 23,-56,-38,-11,-53,-12,-29,-51,-56,-48,-51,-20,-40, -8,-33, 43; M0=-32; /I: MM=0; MI=-107; MD=-117; IM=-9; II=-11; DM=-7; DD=-14; /M: SY='Q'; M=-14,-42, -9, 17,-46,-38,-13, 9, -5,-11,-33, -6,-38, 26, -8, -5, 0, 8,-44,-37; M0=-11; /I: MM=0; MI=-107; MD=-117; IM=-9; II=-11; DM=-7; DD=-14; /M: SY='V'; M=-15,-29,-54,-48, 5,-46,-35, 23,-43, -4,-10, -8,-28,-40,-41,-12,-11, 24, 13, 11; M0=-18; /I: MM=0; MI=-106; MD=-117; IM=-9; II=-11; DM=-7; DD=-14; /M: SY='R'; M=-13,-42,-26, -3,-45,-20,-24,-20, 1,-26,-33, -3,-38, 5, 35,-12,-27, -1, 5,-37; M0=-15; /I: MM=0; MI=-103; MD=-113; IM=-9; II=-11; DM=-7; DD=-14; /M: SY='C'; M=-13, 19,-50,-44,-10,-42, 1, 15,-40, 12, 8, -8,-43,-18,-38, 3, 12, 6, 4, 8; M0=-13; /I: B0=; E1=-10;
Numerical results
UniProtKB/Swiss-Prot release number: 2013_05, total number of sequence entries in that release: 540052. Total number of hits in UniProtKB/Swiss-Prot: 71 hits in 71 different sequences Number of hits on proteins that are known to belong to the set under consideration: 71 hits in 71 different sequences Number of hits on proteins that could potentially belong to the set under consideration: 0 hits in 0 different sequences Number of false hits (on unrelated proteins): 0 hits in 0 different sequences Number of known missed hits: 0 Number of partial sequences which belong to the set under consideration, but which are not hit by the pattern or profile because they are partial (fragment) sequences: 0 Precision (true hits / (true hits + false positives)): 100.00 % Recall (true hits / (true hits + false negatives)): 100.00 %
Comments
MATRIX_TYPE: protein_domain Scaling database: UniProtKB/Swiss-Prot: reversed Matrix author: CJA_Sigrist Taxonomic range: Eukaryotes Maximum known number of repetitions of the pattern in a single protein: 1 FT_KEY: DOMAIN FT_DESC: MHD VERSION: 1
Cross-references
UniProtKB/Swiss-Prot	True positive hits: AP1M1_BOVIN (Q2KJ81), AP1M1_HUMAN (Q9BXS5), AP1M1_MOUSE (P35585), AP1M1_RAT (Q32Q06), AP1M1_SCHPO (Q9HFE5), AP1M1_YEAST (Q00776), AP1M2_BOVIN (Q3SYW1), AP1M2_HUMAN (Q9Y6Q5), AP1M2_MOUSE (Q9WVP1), AP1M_CAEEL (P35602), AP1M_DICDI (Q54HS9), AP1M_DIPOM (P47795), AP2M1_BOVIN (Q3ZC13), AP2M1_CHICK (Q5ZMP6), AP2M1_HUMAN (Q96CW1), AP2M1_MACFA (Q4R706), AP2M1_MOUSE (P84091), AP2M1_PONAB (Q5NVF7), AP2M1_RAT (P84092), AP2M1_XENLA (Q801Q8), AP2M1_XENTR (Q6P856), AP2MA_DANRE (Q6NWK2), AP2MB_DANRE (Q7ZW98), AP2M_CAEEL (P35603), AP2M_DICDI (P54672), AP2M_SCHPO (Q09718), AP2M_YEAST (Q99186), AP3M1_BOVIN (Q24K11), AP3M1_CHICK (Q5ZMP7), AP3M1_HUMAN (Q9Y2T2), AP3M1_MOUSE (Q9JKC8), AP3M1_PONAB (Q5R478), AP3M1_RAT (P53676), AP3M2_HUMAN (P53677), AP3M2_MOUSE (Q8R2R9), AP3M2_RAT (P53678), AP3M_ASHGO (Q750L8), AP3M_DICDI (Q9GPF1), AP3M_SCHPO (O94669), AP3M_YEAST (P38153), AP4M1_BOVIN (Q29RY8), AP4M1_HUMAN (O00189), AP4M1_MOUSE (Q9JKC7), AP4M1_RAT (Q2PWT8), AP4M_DICDI (Q9GPF0), AP5M1_BOVIN (Q5E9X5), AP5M1_HUMAN (Q9H0R1), AP5M1_MACFA (Q4R6Q7), AP5M1_MOUSE (Q8BJ63), AP5M1_RAT (Q499N2), APM2_YEAST (P38700), COPD1_ORYSJ (Q0DJA0), COPD2_ORYSJ (Q0DJ99), COPD3_ORYSJ (P49661), COPD4_ORYSJ (Q0J649), COPD_ARATH (Q93Y22), COPD_BOVIN (P53619), COPD_CAEEL (Q09236), COPD_CHICK (Q5ZL57), COPD_DICDI (Q55EZ6), COPD_HUMAN (P48444), COPD_MOUSE (Q5XJY5), COPD_PONAB (Q5RA77), COPD_RAT (Q66H80), COPD_YEAST (P43621), STNB_CAEEL (P90761), STNB_DROME (Q24212), STON1_HUMAN (Q9Y6Q2), STON1_MOUSE (Q8CDJ8), STON2_HUMAN (Q8WXE9), STON2_MOUSE (Q8BZ60) Retrieve an alignment of UniProtKB/Swiss-Prot true positive hits: [Clustal format, color, condensed view] [Clustal format, color] [Clustal format, plain text] [Fasta format] Retrieve the sequence logo from the alignment
PDB [Detailed view]	1BW8; 1BXX; 1H6E; 1HES; 1I31; 1W63; 2BP5; 2JKR; 2JKT; 2PR9; 2VGL; 2XA7; 3H85; 3L81; 3ML6; 4EMZ; 4EN2; 4HMY; 4IKN;

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