PROSITE entry PS51073

View entry in original PROSITE format
View entry in raw text format (no links)
View entry auxiliary file in raw text format (no links)
Direct ScanProsite submission

General information about the entry

Entry name [info]	RPEL
Accession [info]	PS51073
Entry type [info]	MATRIX
Date [info]	01-JAN-2005 CREATED; 01-OCT-2013 DATA UPDATE; 29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info]	PDOC51073
Associated ProRule [info]	PRU00401

Name and characterization of the entry

Description [info]

RPEL repeat profile.

Matrix / Profile [info]

/GENERAL_SPEC: ALPHABET='ABCDEFGHIKLMNPQRSTVWYZ'; LENGTH=26;
/DISJOINT: DEFINITION=PROTECT; N1=3; N2=24;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=1.2495611; R2=0.0168148; TEXT='NScore';
/CUT_OFF: LEVEL=0; SCORE=432; N_SCORE=8.5; MODE=1; TEXT='R';
/CUT_OFF: LEVEL=-1; SCORE=319; N_SCORE=6.6; MODE=1; TEXT='RR';
/DEFAULT: M0=-8; D=-50; I=-50; B1=-500; E1=-500; MI=-105; MD=-105; IM=-105; DM=-105;

...

                A   B   C   D   E   F   G   H   I   K   L   M   N   P   Q   R   S   T   V   W   Y   Z
/I:         B1=0; BI=-105; BD=-105;
/M: SY='D';  M=-12, 23,-26, 28, 20,-29,-13, -2,-30,  9,-26,-21, 15,-10,  6,  3,  4, -2,-24,-33,-17, 13;
/M: SY='S';  M=  4, -7,-14, -8, -8,-12,-12,-13, -9,-10,-12,-10, -3,-16, -8, -8, 15, 12,  0,-29,-10, -8;
/M: SY='L';  M=-10,-30,-20,-30,-20, 10,-30,-20, 20,-30, 50, 20,-30,-30,-20,-20,-30,-10, 10,-20,  0,-20;
/M: SY='E';  M= -5,  3,-24,  1, 14,-21,-17, -6,-16,  7,-15,-10,  5,-12,  7,  4,  0, -2,-16,-27,-14, 10;
/M: SY='R';  M=-14,-12,-27,-11,  2,-15,-23, -2,-13, 11, -6, -3, -7,-19,  2, 27,-12,-10, -9,-23, -8, -1;
/M: SY='K';  M=-11, -1,-30, -1,  9,-29,-20, -3,-30, 45,-29, -9,  1,-11, 10, 31,-10,-11,-21,-21, -8,  9;
/M: SY='L';  M= -9,-29,-22,-33,-24,  5,-32,-22, 30,-28, 35, 23,-26,-26,-19,-22,-25, -9, 19,-21, -1,-23;
/M: SY='A';  M= 12, -6,-17,-10, -3,-22, -3, -8,-16, -3,-18, -6, -1,-13,  6,  0, 12,  2,-11,-26,-16,  1;
/M: SY='H';  M= -9, -5,-23, -9, -6,-12,-12, 10,-10, -9, -9,  1,  1,-20,  6, -6, -4, -8,-11,-24, -5,  0;
/M: SY='R';  M=-20,-10,-30,-10,  0,-20,-20,  0,-30, 30,-20,-10,  0,-20, 10, 70,-10,-10,-20,-20,-10,  0;
/M: SY='P';  M= -7,-14,-33, -8,  2,-28,-18,-13,-22,  2,-27,-16,-11, 46,  1,  0, -5, -7,-25,-27,-23, -2;
/M: SY='D';  M= -2,  7,-23,  9,  1,-25, -3,-13,-24, -8,-22,-18,  4,  4, -6,-13,  8,  8,-18,-31,-20, -3;
/M: SY='R';  M=-15,-13,-31,-11, -3,-21,-22, -1,-18, 14,-18, -8, -6,  2,  1, 28,-11,-10,-15,-23,-11, -5;
/M: SY='E';  M=  1,  2,-23,  5, 22,-25,-15, -6,-18,  3,-17,-10, -2, -8, 12, -3,  5, -4,-15,-28,-16, 17;
/M: SY='E';  M= -8,  9,-27, 16, 40,-30,-18, -1,-27,  6,-21,-17,  2, -4, 21, -1,  5, -2,-26,-30,-18, 31;
/M: SY='L';  M= -9,-30,-19,-30,-21,  9,-30,-21, 21,-29, 46, 19,-30,-30,-21,-20,-28, -9, 14,-21, -1,-21;
/M: SY='V';  M= -6,-20,-21,-20, -8, -6,-29,-21, 17,-13,  9,  6,-20,-21,-14,-15,-13, -6, 19,-26, -8,-12;
/M: SY='E';  M= -8, 16,-26, 14, 22,-28,-13,  1,-26, 13,-24,-16, 17,-10, 14,  8,  1, -7,-26,-30,-17, 18;
/M: SY='R';  M=-13, -5,-29, -7,  6,-26,-20, -2,-21, 28,-19,  1, -3,-14, 20, 31, -9,-10,-18,-20, -9, 12;
/M: SY='N';  M= -9,  8,-27,  2, -5,-26, 17, 18,-30, -5,-27,-14, 20,-19,  0, -4,  0,-13,-29,-28,-13, -3;
/M: SY='I';  M= -9,-30,-28,-39,-29,  1,-39,-29, 46,-29, 22, 19,-21,-21,-21,-29,-20, -9, 30,-21, -1,-29;
/M: SY='L';  M=-10,-29,-22,-32,-22,  7,-32,-21, 27,-29, 41, 23,-27,-27,-19,-22,-27,-10, 15,-20,  0,-22;
/M: SY='Q';  M=-12, -7,-31, -4, 11,-26,-21, 12,-19, -1,-16, -4, -7, 13, 17,  0, -8,-12,-25,-26,-11, 12;
/M: SY='E';  M= -2,-10,-24,-10,  6, -9,-17,-10,-13, -5,-13, -6,-10,  5, -1, -7, -2, -6,-13,-22,-12,  2;
/M: SY='B';  M= -7,  6,-20,  5,  1,-16,-15, -8,-11, -5, -8, -5,  4,-16, -4, -7,  2,  3, -8,-31,-13, -1;
/M: SY='E';  M= -5,  7,-23,  8, 10,-25,-12, -8,-23,  4,-26,-18,  8,  6,  1, -3,  9,  6,-20,-33,-19,  5;
/I:         E1=0; IE=-105; DE=-105;

» more

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2024_06 which contains 572'619 sequence entries.

Total number of hits	99 in 30 different sequences
Number of true positive hits	99 in 30 different sequences
Number of 'unknown' hits	0
Number of false positive hits	0
Number of false negative sequences	0
Number of 'partial' sequences	0

Precision (true positives / (true positives + false positives))	100.00 %
Recall (true positives / (true positives + false negatives))	100.00 %

Comments [info]

Taxonomic range [info]	Eukaryotes
Maximum number of repetitions [info]	4
Matrix type [info]	protein_domain
Scaling database [info]	reversed
Author [info]	CJA_Sigrist
Feature key [info]	REPEAT
Feature description [info]	RPEL
Version [info]	4

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences

30 sequences

MRTFA_HUMAN (Q969V6), MRTFA_MOUSE (Q8K4J6), MRTFA_XENLA (Q8AYC2),

MRTFB_HUMAN (Q9ULH7), MRTFB_MOUSE (P59759), MRTFB_XENLA (Q8AYC1), 
MYCD_HUMAN  (Q8IZQ8), MYCD_MOUSE  (Q8VIM5), MYCD_PIG(Q7YR76), 
MYCD_RAT(Q8R5I7), PHAR1_CHICK (Q801X6), PHAR1_HUMAN (Q9C0D0), 
PHAR1_MOUSE (Q2M3X8), PHAR1_RAT   (P62024), PHAR1_XENLA (Q6GLU8), 
PHAR2_HUMAN (O75167), PHAR2_RAT   (P62025), PHAR3_HUMAN (Q96KR7), 
PHAR3_MOUSE (Q8BYK5), PHAR3_RAT   (Q6RFY2), PHAR4_BOVIN (F1MCY2), 
PHAR4_CHICK (F1N8V3), PHAR4_HUMAN (Q8IZ21), PHAR4_MOUSE (Q501J7), 
PHAR4_PONAB (Q5RAU1), PHAR4_XENTR (F7EC58), PHR4A_DANRE (F1QIC4), 
PHR4A_XENLA (Q5HZA1), PHR4B_DANRE (Q6PEI3), PHR4B_XENLA (Q5XHF3)

» more

Retrieve an alignment of UniProtKB/Swiss-Prot true positive hits:
[Clustal format, color, condensed view] [Clustal format, color]
[Clustal format, plain text] [Fasta format]
Retrieve the sequence logo from the alignment

PDB
[Detailed view]

10 PDB

2V51; 2V52; 2YJE; 2YJF; 4B1U; 4B1V; 4B1W; 4B1X; 4B1Y; 4B1Z