PROSITE entry PS51156
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General information about the entry
| Entry name [info] | ELM2 |
| Accession [info] | PS51156 |
| Entry type [info] | MATRIX |
| Date [info] |
01-OCT-2005 CREATED;
10-MAY-2017 DATA UPDATE; 29-MAY-2024 INFO UPDATE. |
| PROSITE Doc. [info] | PDOC51156 |
| Associated ProRule [info] | PRU00512 |
Name and characterization of the entry
| Description [info] | ELM2 domain profile. |
| Matrix / Profile [info] |
/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=97; /DISJOINT: DEFINITION=PROTECT; N1=6; N2=92; /NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=2.4636354; R2=0.0065040; TEXT='NScore'; /NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=13380.1767578; R2=5.6353655; PRIORITY=1; TEXT='Heuristic 5.0%'; /CUT_OFF: LEVEL=0; SCORE=929; H_SCORE=18615; N_SCORE=8.5; MODE=1; TEXT='!'; /CUT_OFF: LEVEL=-1; SCORE=621; H_SCORE=16880; N_SCORE=6.5; MODE=1; TEXT='?'; /DEFAULT: M0=-31; D=-90; I=-90; B1=-500; E1=-500; MI=-255; MD=-255; IM=-255; DM=-255; ... A C D E F G H I K L M N P Q R S T V W Y /I: B1=0; BI=-255; BD=-255; /M: SY='G'; M= -16, -82, -69, 1, -82, 55, -18, -82, 45, -53, -79, 21, 40, -72, 12, -5, -37, -59, -77, -13; /M: SY='E'; M= -28, 37, -68, 71, -84, -35, 18, -37, 45, -54, -19, -40, -32, -17, 19, 9, -23, -84, -80, -31; /M: SY='I'; M= -40, -28, -85, -82, -70, -77, -75, 102, -45, -62, 8, -31, -84, -79, -80, -16, -4, -14, -89, -74; /M: SY='R'; M= -47, -77, -71, -72, -77, -59, -18, -81, -44, -46, 72, 71, -32, -62, 89, -29, -79, -80, -85, -73; /M: SY='V'; M= -46, -78, -39, -50, -68, -49, -80, 24, -80, -9, -73, -77, -88, -85, -39, -73, -25, 94, -91, -67; /M: SY='G'; M= -74, -88, -2, -44, -89, 102, -78, -47, -75, -82, -85, -68, -72, -81, -77, -64, -83, -88, -66, -88; /M: SY='P'; M= -29, -17, -9, 25, -83, -41, 24, -82, -33, -19, -85, -1, 76, -71, -21, 49, 14, -83, -86, -25; /I: I=-20; MI=0; MD=-57; IM=0; DM=-57; /M: SY='Q'; M= -17, -75, 28, 43, -83, -78, -31, -84, 36, -29, 30, 6, -73, 44, 39, 8, -29, -82, 3, -75; /M: SY='Y'; M= -86, -20, -82, -53, 75, -88, 70, -49, -78, -60, -78, -82, -82, -31, -33, -74, -82, -9, -56, 103; /M: SY='Q'; M= -44, -79, -69, -58, -89, -82, -65, -84, -71, -79, -81, -74, -71, 131, -14, -31, -77, -90, -76, -7; /M: SY='A'; M= 95, -28, -20, -69, -79, -74, -76, -75, -30, -77, -72, -71, -76, -65, -71, -62, -32, -6, -96, -30; /M: SY='E'; M= -64, -75, 45, 51, -84, -47, -15, -28, 28, -42, 20, -70, -29, 34, -10, -20, 11, 21, -85, -75; /M: SY='I'; M= -73, -22, -81, -81, -30, -80, -76, 81, -80, 23, -71, -10, -6, -81, -79, -73, -44, 49, -88, -68; /M: SY='P'; M= -55, -30, -16, -40, -90, -46, -62, -84, -33, -46, -94, -5, 114, -18, -73, -42, 3, -18, -87, -80; /M: SY='P'; M= -36, -75, 65, 51, -27, -45, -68, -59, -33, -30, -48, -23, 65, -13, -72, -6, -35, -8, -85, -77; /M: SY='W'; M= -49, 23, -43, -75, 55, 2, -75, -18, -41, 37, 29, -39, -84, -26, -28, -74, -18, -48, 93, 33; /M: SY='Q'; M= -11, 14, -23, -33, 10, -36, 7, 12, 3, 26, -8, 12, -19, 35, -3, -70, 15, -3, -82, -9; /M: SY='P'; M= -41, 58, 5, 27, 0, 16, -70, -80, 15, -36, -84, -23, 67, -18, -50, -21, -45, -3, -78, -9; /M: SY='R'; M= -23, 1, 10, 33, -16, -59, -28, 1, -14, -3, -79, 6, 33, 0, 54, 2, -48, -61, -81, -17; /M: SY='Y'; M= -9, 4, -7, 9, -77, 20, -69, -52, -34, -26, -82, 14, 27, 6, -6, 35, 9, -60, 3, 50; /M: SY='E'; M= -3, -76, 24, 45, -40, -15, 10, -79, 19, -25, -79, 2, 25, -34, 2, 8, -24, 14, -84, -36; /M: SY='D'; M= 6, -15, 28, 23, -6, -4, -7, -56, 0, -32, -80, -21, 7, 8, 23, 24, -15, -35, -79, 24; /M: SY='D'; M= -3, 15, 50, 39, -82, -25, -23, -52, -53, -35, 12, 13, -22, -3, 13, 15, 2, -51, 7, 23; /M: SY='E'; M= 4, -15, 25, 41, -58, -17, -45, -35, -6, -9, -79, 4, 5, 33, -9, 13, -20, -26, -80, 24; /M: SY='D'; M= -26, -19, 58, 38, -85, -28, -18, -47, 48, -54, -24, -13, -18, -10, 21, 6, -28, -59, -83, -33; /M: SY='D'; M= -14, -78, 34, 32, -5, -78, -70, -44, 22, -46, -25, 17, 17, 23, 4, 1, -11, -6, -80, 32; /M: SY='D'; M= 0, -79, 45, 17, -79, -79, 44, -32, 14, -20, -20, -2, 4, 35, 13, -39, -78, -39, 31, 41; /I: I=-4; MD=-10; /M: SY='E'; M= -35, -78, 23, 58, -91, -4, -74, -88, 3, -63, -85, 44, -8, 15, -29, -15, 8, -62, -89, -42; D=-4; /I: I=-4; MD=-10; /M: SY='N'; M= -72, -22, 17, 32, -93, -51, 14, -3, 2, -36, -88, 36, 2, -8, -55, -43, 4, -17, -98, -37; D=-4; /I: I=-4; MI=0; MD=-10; IM=0; DM=-10; /M: SY='R'; M= -24, -86, -11, 2, -86, -9, -7, -89, -14, 27, 3, -62, -52, -42, 36, -35, 10, -87, 5, -79; D=-4; /I: I=-4; DM=-10; /M: SY='D'; M= 44, -76, 65, 58, -90, 24, -73, -85, -47, -78, -82, -69, -72, -69, -73, 2, -76, -52, -85, -85; D=-4; /I: I=-4; DM=-10; /M: SY='Q'; M= -69, -74, 1, 54, -83, -80, -28, -4, -24, -33, 56, -70, -74, 59, -34, -11, 50, -1, -85, -75; /M: SY='L'; M= -57, -25, -26, -69, -67, -80, -71, -2, 17, 67, -8, -76, 4, 17, 10, -15, -74, -12, -83, -62; /M: SY='V'; M= -72, -4, -77, -78, -66, -83, -28, 26, -48, 44, 40, -20, -87, -81, -22, -75, -71, 69, -15, -64; /M: SY='W'; M= -94, -74, 8, -72, -14, -42, -83, -87, -32, -76, -87,-100, -37, -75, -67, -84, -96, -88, 166, 55; /M: SY='S'; M= -39, 22, 32, -2, -81, -76, -3, -31, -10, -59, -17, 27, 18, 8, 19, 53, 9, -7, -89, -78; /M: SY='P'; M= -21, -8, -71, -64, -45, -74, -62, -46, -67, -25, -95, -46, 115, -27, -39, 12, -48, -87, -86, -80; /I: I=-4; MD=-11; /M: SY='W'; M= -57, -78, 33, 35, -69, 10, -2, -37, -55, -36, -83, 27, 26, -6, -14, 5, 0, -57, 59, 40; D=-4; /I: I=-4; MD=-11; /M: SY='N'; M= -40, 6, 2, 24, -79, -34, 34, -8, -33, -13, 11, 47, -25, 36, -71, 15, -38, 24, -88, -28; D=-4; /I: I=-4; MD=-11; /M: SY='L'; M= -23, -43, 4, 31, -60, -48, -6, -13, -74, 36, -17, -2, 22, 12, -76, 4, -7, -6, -88, -35; D=-4; /I: I=-4; MD=-11; /M: SY='L'; M= -64, -21, 10, 21, -84, -91, -82, 1, -4, 37, 19, 8, -38, -49, -85, -55, -28, -28, -96, -43; D=-4; /I: I=-4; MI=0; MD=-11; IM=0; DM=-11; /M: SY='P'; M= -46, 15, 23, 6, -53, -56, -22, -82, 3, -58, -55, 15, 54, -19, -23, 24, 45, -12, -92, -81; D=-4; /I: I=-4; DM=-11; /M: SY='D'; M= -71, -73, 79, 63, -40, -55, -30, 12, -12, -75, -83, -13, -24, 22, -30, -19, -78, -38, -85, -78; /M: SY='K'; M= 5, 5, -8, 48, -83, -28, -70, -84, 50, -55, -77, 11, -51, 31, 30, 19, -25, -83, -83, -79; /M: SY='Q'; M= -13, -77, 31, 26, -40, -78, -70, -30, 51, -45, -54, 32, -12, 67, 17, -68, -77, -31, -84, -77; /M: SY='I'; M= -49, -73, -15, 16, -68, -81, -75, 60, -76, 41, -71, -74, -83, -78, -22, -73, -20, 49, -86, -66; /M: SY='D'; M= -44, -74, 74, 49, -37, -54, -72, -7, 9, -18, -27, 19, -73, -21, -12, -43, -2, -52, -84, -2; /M: SY='E'; M= -9, -71, 21, 74, -87, -79, -66, -59, -35, -75, 28, 17, -72, 64, -9, -10, -27, -42, -81, -12; /M: SY='Y'; M= -86, -85, -39, -81, 81, -86, -72, -73, -77, 21, -78, -26, -86, -80, -68, -41, -51, -52, 4, 100; /M: SY='L'; M= 4, -26, -74, -1, -66, -80, -70, 32, -39, 66, 56, -75, -83, -75, -76, -18, -73, -30, -2, -63; /M: SY='S'; M= 2, -76, -6, 0, -74, -77, -73, 4, 14, 3, -26, 20, -78, -73, 10, 36, 13, 30, -88, -25; /M: SY='V'; M= 3, -11, 27, 26, 3, -81, -73, -7, 11, 4, 13, -74, -79, -37, -5, -28, -49, 39, -80, 28; /M: SY='A'; M= 76, -22, -68, -32, -77, -45, -76, 36, -73, -73, -73, -1, -78, -70, -74, -6, 12, 10, -95, -85; /M: SY='R'; M= -31, 47, -71, -27, -78, -79, -26, -82, 53, -48, -76, -73, -74, 31, 67, 30, -15, -9, -2, -73; /I: I=-5; MD=-13; /M: SY='S'; M= 7, 14, -29, 28, -87, -23, -79, -89, -20, -12, -18, -81, -84, -79, 1, 60, -81, -88, -93, -30; D=-5; /I: I=-5; MD=-13; /M: SY='M'; M= -49, 31, -95, -92, -89,-100, -30, -18, -90, 2, 47, -95, -46, -90, 37, -45, -95, 21, 4, -14; D=-5; /I: I=-5; MD=-13; /M: SY='A'; M= 34, -30, -54, -94,-101, 26, -96, -22, -91, -97, -97, -90, -94, -88, 24, -40, 20, -93,-102,-102; D=-5; /I: I=-5; MD=-13; /M: SY='T'; M= -4, -48, -51, -90,-102, 15, -98, -99, 28, -42, -97, -50, -39, -95, -94, -85, 43, -58, 3,-100; D=-5; /I: I=-5; MD=-13; /M: SY='F'; M= -35, -98, 6, -23, 56, -58, -47, -52, -28, -64,-101, 27,-101, 19, -89, -23, -48, -97, -99, -38; D=-5; /I: I=-5; MD=-13; /M: SY='W'; M= 27, -94, -90, 26, -99, -32, 21,-101, -59, -24, -38, -96, -37, 1, -90, -89, -18, -99, 81, -89; D=-5; /I: I=-5; MD=-13; /M: SY='R'; M= -45,-101, -20, -22,-101, 8, -93,-105, 36, -51, 4, -93, -93, -85, 56, -88,-103,-102, -97, -94; D=-5; /I: I=-5; MD=-13; /M: SY='A'; M= 32,-104, -95, -95,-103, -28, -95, -57, -96, -25, 30, -97,-104, 27, -58, 8, -96, -39,-113,-104; D=-5; /I: I=-5; MI=0; MD=-13; IM=0; DM=-13; /M: SY='C'; M= 26, 46, -2, -88, -98, -62, -93, 16, -91, -55, -97, 6, -16, -10, -30, 8, -91, -54,-108,-102; D=-5; /I: I=-5; DM=-13; /M: SY='P'; M= 37, -94, -47, -26, -95, -64, -21, -54, -57, -40, -32, -11, 43, -5, -86, 1, -51, 0,-104, -39; D=-5; /I: I=-5; DM=-13; /M: SY='A'; M= 47, 19, 0, 13, -10, -61, -80, -86, -79, 5, -13, -83, 35, -15, -52, -29, -83, -38, -95, -87; D=-5; /I: I=-5; DM=-13; /M: SY='G'; M= 42, -30, -42, 43, -20, 50, -71, -82, -7, -53, -81, -72, 42, -13, -45, -23, -48, -82, -78, -44; /M: SY='W'; M= -33, 15, -42, 2, -75, -2, -3, -55, 15, -41, -27, -21, -75, -32, 26, 60, 1, -26, 74, 8; /M: SY='H'; M= -6, -83, -74, -21, -40, 1, 93, -78, -72, -22, -75, -33, -74, -69, 54, 24, -79, 5, -78, 37; /M: SY='D'; M= -45, -81, 67, -70, -85, 36, 17, 0, -43, -24, -82, -37, 27, -32, -74, 4, 21, 7, -85, -77; /M: SY='I'; M= -34, -80, -3, -74, 33, -80, -23, 44, 24, -21, -75, 9, -79, -72, 44, -26, 11, -35, -76, 43; /M: SY='D'; M= -44, -77, 65, -39, -39, -75, -72, -79, -71, -14, -82, 59, 16, -73, -76, 21, 64, -77, -97, -78; /M: SY='N'; M= -73, -75, -3, -1, -15, -39, -21, -1, -1, 25, 43, 48, 33, 31, -71, -11, 7, -41, -87, -72; /M: SY='E'; M= -75, -67, 32, 94, 44, -81, -69, -29, -24, -26, -81, -72, -70, -31, -72, -70, -45, -83, 10, -72; /M: SY='Q'; M= -50, -80, -15, -13, 13, -83, 73, -78, -21, -12, -76, 3, -74, 88, -11, -46, -13, -10, -78, 33; /M: SY='A'; M= 98, -79, -64, -70, -80, -73, -76, -29, -71, -78, -72, -71, -76, -64, -33, -31, -47, -30, -98, -92; /M: SY='L'; M= -49, -72, -75, -73, 3, -82, -19, -16, -75, 75, 69, -77, -47, -77, -40, -29, -73, -66, -78, 25; /M: SY='H'; M= -23, 11, 49, -37, -4, 15, 67, -32, 24, -72, -77, 8, -74, 15, -42, -70, -53, -80, -72, 66; /M: SY='M'; M= -29, 31, -73, 41, -76, -81, -19, 33, -71, 22, 64, -71, -78, -13, -75, -43, 51, -26, 6, -46; /M: SY='L'; M= -80, -68, -72, -71, -59, -83, -71, -64, -30, 93, -63, -78, -85, -78, -78, -77, -72, -64, -83, -54; /M: SY='H'; M= -79, -84, -80, -73, 48, -85, 108, -45, -46, 0, 32, -36, -77, 3, -21, -72, -18, 16, -79, 35; /M: SY='W'; M= -63, -78, -17, 24, -15, -77, -1, -32, 62, -77, -76, -3, -72, 28, 46, -25, -83, -83, 91, 13; /M: SY='C'; M= 16, 89, -70, -31, -81, -79, 84, -78, -45, -59, -77, 62, -78, -31, -73, 29, -29, -26, -92, -41; /M: SY='N'; M= -72, -79, 21, -25, -81, 39, -32, -35, 55, -80, -76, 77, -74, -20, -18, -8, -56, -75, -86, -84; /M: SY='Y'; M= -86, -91, -79, -78, 60, 17, 77, -77, -78, -46, -78, -21, -79, -78, -68, -72, -16, -75, -56, 102; /M: SY='D'; M= -70, -76, 94, -36, -89, -73, -73, -49, -27, -78, -85, 84, -78, -73, -34, 7, -72, -83, -99, -83; /M: SY='I'; M= -2, -78, -77, -77, 21, -79, -74, 61, -39, 8, -42, -73, 40, -78, -76, -5, 20, 26, -85, -28; /M: SY='E'; M= -9, -73, 24, 72, -86, -3, 25, -85, 35, -38, -6, -2, -16, -35, -44, 4, -58, -55, -83, -80; /M: SY='K'; M= -5, -74, 0, 60, -82, -78, -70, -85, 62, -26, -74, -71, -69, 11, 37, 5, -54, -49, -81, -76; /M: SY='A'; M= 91, -79, -64, -70, -79, -72, -74, -76, -70, -79, -75, -70, -75, -66, -71, 41, -7, -39, -98, -91; /M: SY='L'; M= -76, -25, -76, -74, -64, -81, -16, 45, -3, 67, 41, -75, -85, -79, -76, -39, -73, 9, -83, -11; /M: SY='E'; M= 18, -32, -18, 54, -81, -77, -28, -47, 10, -48, -18, -12, -72, 33, 36, 42, -48, -50, -83, -23; /M: SY='R'; M= 4, -78, 45, 1, -78, -79, -71, -19, -8, -22, 11, -72, -76, 7, 60, 20, -1, -27, -81, 19; /M: SY='L'; M= -52, -23, -75, -73, 5, -83, -27, -11, -29, 79, 42, -77, -86, -78, -75, -77, -74, -46, -78, 24; /M: SY='P'; M= 8, 37, -17, -38, -76, -79, -16, -73, 17, 3, 11, 19, 42, -72, 34, -25, -74, 38, -87, -74; /M: SY='P'; M= -35, 36, -31, -21, 40, -77, -70, -47, 18, -15, -26, 43, 54, 7, -4, 27, -27, -49, -83, -74; /M: SY='N'; M= -53, 10, -49, -71, 47, -77, -27, -54, 2, -39, -80, 68, 1, 31, 21, 34, -21, -18, -84, -38; /M: SY='T'; M= -38, -79, 30, 3, -82, 28, 11, -52, -10, -23, -21, 17, 28, -33, -29, -22, 40, 23, -86, -77; /I: E1=0; IE=-255; DE=-255;» more |
Numerical results [info]
| Total number of hits | 46 in 46 different sequences |
| Number of true positive hits | 46 in 46 different sequences |
| Number of 'unknown' hits | 0 |
| Number of false positive hits | 0 |
| Number of false negative sequences | 0 |
| Number of 'partial' sequences | 0 |
| Precision (true positives / (true positives + false positives)) | 100.00 % |
| Recall (true positives / (true positives + false negatives)) | 100.00 % |
Comments [info]
| Taxonomic range [info] | Eukaryotes |
| Maximum number of repetitions [info] | 1 |
| Matrix type [info] | protein_domain |
| Scaling database [info] | reversed |
| Author [info] | CJA_Sigrist |
| Feature key [info] | DOMAIN |
| Feature description [info] | ELM2 |
| Version [info] | 5 |
Cross-references [info]
| UniProtKB/Swiss-Prot True positive sequences |
46 sequences
ARID1_ARATH (Q84JT7), ARID2_ARATH (Q9LDD4), EGL27_CAEEL (Q09228), MDEAS_HUMAN (Q6PJG2), MIER1_CHICK (Q5ZKT9), MIER1_HUMAN (Q8N108), MIER1_MOUSE (Q5UAK0), MIER1_PONAB (Q5REE1), MIER1_XENLA (Q7T105), MIER2_BOVIN (A5PJX4), MIER2_HUMAN (Q8N344), MIER2_MOUSE (Q3U3N0), MIER3_HUMAN (Q7Z3K6), MIER3_MACFA (Q4R3R9), MIER3_MOUSE (Q3UHF3), MTA1_HUMAN (Q13330), MTA1_MOUSE (Q8K4B0), MTA1_RAT(Q62599), MTA2_HUMAN (O94776), MTA2_MOUSE (Q9R190), MTA3_BOVIN (A6QL72), MTA3_HUMAN (Q9BTC8), MTA3_MOUSE (Q924K8), RCOR1_HUMAN (Q9UKL0), RCOR1_MOUSE (Q8CFE3), RCOR1_XENLA (Q90WN5), RCOR2_DANRE (Q6P116), RCOR2_HUMAN (Q8IZ40), RCOR2_MOUSE (Q8C796), RCOR2_RAT (Q5FWT8), RCOR2_XENLA (Q6NRZ0), RCOR3_CHICK (Q5ZJ40), RCOR3_HUMAN (Q9P2K3), RCOR3_MOUSE (Q6PGA0), RCORA_CAEEL (Q95Y41), RCORB_CAEEL (Q18919), RCOR_DROME (Q59E36), RERE_HUMAN (Q9P2R6), RERE_MOUSE (Q80TZ9), RERE_RAT(Q62901), SAEG1_CAEEL (Q20733), TREF1_HUMAN (Q96PN7), TREF1_MOUSE (Q8BXJ2), ZN541_HUMAN (Q9H0D2), ZN541_MACFA (Q4R2Z8), ZN541_MOUSE (Q0GGX2)» more
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| PDB [Detailed view] |
36 PDB
2XAF; 2XAG; 2XAH; 2XAJ; 2XAQ; 2XAS; 3ZMS; 3ZMT; 3ZMU; 3ZMV; 3ZMZ; 3ZN0; 3ZN1; 4BKX; 4CZZ; 4UV8; 4UV9; 4UVA; 4UVB; 4UVC; 4UXN; 5ICN; 5L3B; 5L3C; 5L3D; 5LHG; 5LHH; 5LHI; 6TE1; 6TUY; 6Z2J; 6Z2K; 7AO8; 7AO9; 7AOA; 9FWG » more |