Entry: PS51180

Forthcoming changes to the profile format
General information about the entry

Entry name [info] BRO1
Accession [info] PS51180
Entry type [info] MATRIX
Date [info] JAN-2006 (CREATED); OCT-2013 (DATA UPDATE); MAR-2014 (INFO UPDATE).
PROSITE Doc. [info] PDOC51180
Associated ProRule [info] PRU00526

Name and characterization of the entry

Description [info] BRO1 domain profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=388;
/DISJOINT: DEFINITION=PROTECT; N1=6; N2=383;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=-1.6812770; R2=0.0047889; TEXT='NScore';
/NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=-7046.14996; R2=38.13972; TEXT='HScore';
/CUT_OFF: LEVEL=0; SCORE=2314; N_SCORE=9.4; H_SCORE=105886; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=1709; N_SCORE=6.5; H_SCORE=58096; MODE=1; TEXT='?';
/DEFAULT: M0=-41; D=-50; I=-50; B1=-300; E1=-300; MI=-105; MD=-105; IM=-105; DM=-105;
...
                A    C    D    E    F    G    H    I    K    L    M    N    P    Q    R    S    T    V    W    Y
/I:         B1=0; BI=-105; BD=-105;
/M: SY='P'; M= -33, -96, -10,  27, -88, -26,  33, -14, -74, -90, -82,  51,  84,  -2, -81, -24, -14, -31, -95,  19;
/M: SY='L'; M= -82, -89, -99, -92,  53, -98, -86,  16, -92,  62,  51, -94,  21, -89, -92, -16, -78,  11, -84, -65;
/M: SY='I'; M= -84, -91, -99, -96,  40,-101, -83,  66, -93,  50,  20, -94, -97, -88, -92, -26, -79, -53, -75,  59;
/M: SY='P'; M=  27, -92,  10, -77, -17, -10, -81, -82, -80, -14, -79,  -1,  65, -14, -85,  33,  -7, -32,  65,  24;
/M: SY='I'; M= -31, -90,-100, -95,  15, -25, -92,  68, -93,  47, -55, -94,  -5, -91, -94, -88, -77,  29, -86,   6;
/M: SY='P'; M= -80,-102, -15, -17,-101,   4, -80, -91,  21, -97, -85,  -7, 104,  43, -10, -76, -77, -30, -96, -92;
/M: SY='L'; M= -83,   4, -96, -90,  56, -98, -84, -21, -21,  70, -56, -90, -97, -87, -26, -30,  23, -63, -81,  -5;
/I:         I=-14; MI=0; MD=-29; IM=0; DM=-29;
/M: SY='K'; M= -81, -97, -75, -62, -96, -88, -76, -95,  97, -95, -83, -69,  49, -61,  42, -75, -12, -92, -92, -85;
/M: SY='T'; M= -10, -89,  30,  50, -93, -85, -75, -89,  35, -88,   5,   0, -80,  -7,  19, -19,  64, -83,-100, -85;
/M: SY='T'; M=   9, -80, -10, -76, -87, -81, -84, -79, -75, -83, -79, -65, -78, -77, -83,  26, 108, -71,-104, -84;
/M: SY='S'; M= -74,  17,  19,  41,  -7, -28,  -1, -86,  25,  -3, -80,  13, -83,  -4, -72,  47,  33, -83, -97, -80;
/I:         I=-10; MI=0; MD=-21; IM=0; DM=-21;
/M: SY='E'; M=  -7, -94,  32,  54, -94, -84,  39, -30,  -4, -32, -81,  -2,  47,  34, -74,  17, -25, -33,-100, -84;
/M: SY='V'; M= -25, -86, -98, -93,  32, -98, -93,  36, -92,  44, -57, -92, -95, -91, -93, -21,   5,  62, -90, -70;
/I:         I=-15; MI=0; MD=-32; IM=0; DM=-32;
/M: SY='D'; M= -76, -91, 101, -57, -99, -77,  11, -98, -72, -99, -94,  34, -84, -70, -79,  54,  -9, -94,-114, -85;
/M: SY='W'; M= -89, -96,-104, -17,  74, -98, -92, -66, -91,  50,   8,-101, -99, -90, -91, -94, -88, -73, 131, -50;
/M: SY='S'; M=  24, -86, -79, -15, -88,   4, -82, -23,  27, -30, -76, -72, -84,  37, -74,  53,  10,  28, -96, -83;
/M: SY='K'; M=  -4, -90,  26,   4, -91, -84, -77, -84,  59, -32, -80, -13,  -9,   6,  20,  -1,  46, -12, -98, -84;
/M: SY='P'; M=  42, -94, -80,  14, -93,  15,  10, -19, -72, -31, -79, -79,  73,  -6,  30, -20, -76, -35, -95, -87;
/M: SY='L'; M= -84, -88,-102, -96,  31,-103, -88,  29, -95,  80,  19, -99,-100, -90, -93, -93, -80,  -2, -85, -66;
/M: SY='K'; M= -10, -87, -74, -72, -89, -29,  11, -30,  48, -37, -79,  31, -84, -10,  32,  43,  44, -28, -98, -82;
/M: SY='S'; M= -30,  45,  45,   8, -10, -80,   3, -89,  17, -90, -84,  26, -85,  29,   5,  48,   7, -29,-100, -81;
/M: SY='Y'; M= -85,  17,  -9, -22,  57, -96,  11,  -1, -86,  -2, -67, -87,  -5, -84, -86, -84, -19,   8, -65,  97;
/M: SY='I'; M= -79, -92, -96, -92, -69,-100, -94,  90, -17,  23, -56, -88, -91, -85, -11,   4, -16,   5, -92, -75;
/M: SY='S'; M=  -9, -89,  24,   7, -81, -82,  38, -81,  30,  23, -74,  -8, -85,  -4, -22,  51,   2, -80, -94,   6;
/M: SY='N'; M=   3, -89, -21,  -3,  -7, -81, -75, -83,  16, -32,   2,  40,  17,  26,  30,  36,  20, -29, -95, -81;
/M: SY='H'; M= -72, -88, -74, -24, -83, -24,  61,  22,  -7, -81, -75,  28, -84,  26, -76,  47,  57, -25, -97,   5;
/M: SY='Y'; M= -85, -93, -90, -91,  52, -94, -64, -68, -85,   3, -66, -88, -98, -82, -84,   1, -11, -18, -55, 117;
/I:         I=-8; MI=0; MD=-17; IM=0; DM=-17;
/M: SY='D'; M= -81, -98,  53, -78,  22,  32, -79, -96, -83, -95, -91,  19, -10, -12, -89,  37, -17, -95, -91,  41; D=-8;
/I:         I=-8; DM=-17;
/M: SY='Q'; M=  15, -94,   8,  48,-100,   7,   3, -95, -67, -93, -84,  -8, -83,  79, -22,  -3,  23, -90, -99, -86; D=-8;
/I:         I=-8; DM=-17;
/M: SY='D'; M=  -3, -94,  55, -18, -89, -83,  33, -89, -72, -91, -84,  50,  27,  41, -27, -69,  36, -31, -99,  25; D=-8;
/I:         I=-8; DM=-17;
/M: SY='W'; M=  27, -95, -84, -78, -91,   4,  14, -94, -71, -94, -86, -78,  56,  -5,  45,  34,   1, -89,  85, -80; D=-8;
/I:         I=-8; DM=-17;
/M: SY='S'; M=  20, -90,  19,  39, -91, -27,  41, -89,  -5, -44, -84, -15, -84, -68, -23,  57, -21, -26, -99, -13; D=-8;
/I:         I=-8; DM=-17;
/M: SY='Q'; M=   8, -91,  12,  17, -19, -84, -77, -80,  -1, -44,  24,  10, -87,  46,  27,  35, -22,   8, -98, -82; D=-8;
/I:         I=-8; DM=-17;
/M: SY='F'; M= -87, -92, -99, -97,  90,-100, -77, -62, -92, -28, -67, -93,-102, -94, -90, -87, -12,  34, -62,  86; D=-8;
/I:         I=-8; DM=-17;
/M: SY='R'; M=  11,  10,  12,  40, -84, -85, -71, -28,  11, -87, -80,  14, -86,  44,  52, -27, -18, -85, -87,  44;
/M: SY='D'; M=   6, -92,  69,  52, -92, -82,   2, -90,   6,   0, -83,  18, -83, -65,   5,  16, -73, -87,-102, -84;
/M: SY='D'; M=  20, -95,  86,  54,-101, -33,  18, -97, -68, -94, -89, -63, -81,  50, -75, -69, -16, -92,-105, -85;
/I:         I=-11; MI=0; MD=-23; IM=0; DM=-23;
/M: SY='L'; M= -32,  48, -99, -95,  -4,-100, -93,  54, -94,  58, -57, -93, -97, -91, -95, -31,  15,   1, -94, -75; D=-11;
/I:         I=-11; DM=-23;
/M: SY='K'; M=  27, -92,  21,  20, -93, -24, -79, -30,  54, -22, -81, -14, -85,  19, -15,  12, -17, -34, -97, -86; D=-11;
/I:         I=-11; DM=-23;
/M: SY='E'; M=  18, -92,   3,  61, -92, -23, -79, -35,  27, -88, -83, -73, -82,  18, -72,   0,  32,  -8, -96,  -9; D=-11;
/I:         I=-11; DM=-23;
/M: SY='L'; M= -32, -89, -99, -94,  43,-101,  37,  42, -93,  65,   6, -93, -97, -89, -91, -90, -79,  11, -86, -64;
/M: SY='N'; M= -24, -90,  58,   5, -92, -81, -72, -81,  25, -86,  26,  69, -85,  19, -20, -21,   9,  11,-104, -84;
/M: SY='R'; M=   7, -93,  51, -64, -94, -28,  52, -94,  35, -39, -81,  17, -86,  37,  53, -25, -14, -90,-100, -80;
/M: SY='L'; M=   7,  32, -95, -90, -64, -94, -82, -56, -90,  75,  55,  -6, -97, -85, -89, -84, -13, -26, -90,  -2;
/M: SY='R'; M= -84,-101, -79, -12, -95, -93, -71, -99,  16, -93, -82, -74,  17, -58, 112, -78, -82, -94, -93, -82;
/M: SY='Q'; M= -78, -94, -13, -14,  -9, -81, -69, -32,   9, -90, -80,  66,  20,  87,  21,   7, -21, -89, -95, -81;
/M: SY='N'; M=  25, -89,  60,   4, -96,   0, -73, -90, -20, -93, -86,  63, -84,  24, -18,   1,  10, -29,-103, -87;
/M: SY='A'; M=  69,  31, -91, -86, -12, -20, -90,  33, -86,   6,   8, -84, -89, -82, -89,   2, -73,  -7,  36, -78;
/M: SY='R'; M=  10,  44, -83, -79, -14, -86, -81,   9, -70, -14, -71,  35, -92,  22,  51,   3, -10,  37, -97, -79;
/M: SY='N'; M=  -5,  12, -11, -20, -90,  38,   9, -19, -26, -31,   6,  48, -86,  -9,  21,  14,  32, -82, -99, -84;
/M: SY='P'; M=   6, -92,  21,  29, -85, -13, -83, -25, -77,  13, -73, -79,  58,  -4, -19,   6, -73,  34, -98, -85;
/M: SY='D'; M=  27, -90,  39, -69, -91,  -8,  18, -86,  28,   3, -79,  10,  32,  16, -23,  34, -71, -84, -98, -83;
/M: SY='R'; M=  23, -91,  10,  -6,  -9,   2,  10, -26, -26,  11, -74,  31,  32, -74,  40, -74, -76,   0, -95, -80;
/M: SY='D'; M=   2,  11,  61,   2, -91,   2, -77, -85, -76,   0, -82,  39,  23, -73, -83,  38, -12, -33,-103, -87;
/M: SY='D'; M=   8, -91,  54,  25, -15, -83,  26,   3,   2, -35, -79,  25,  -3,  19, -76,  11, -15,  -6,-100, -80;
/I:         I=-8; MI=0; MD=-16; IM=0; DM=-16;
/M: SY='H'; M=  32, -87, -17,   7, -90, -80,  53, -16, -76, -84, -79,  18, -18, -11, -81,  42,  45,   8,-103, -82; D=-8;
/I:         I=-8; MI=0; MD=-16; IM=0; DM=-16;
/M: SY='G'; M=   5, -95,  21, -86, -89,  64, -88, -24, -88,   3, -81, -12, -93,   1, -93, -15, -82,   0, -97,  -6; D=-8;
/I:         I=-8; DM=-16;
/M: SY='L'; M= -26,  12, -24, -28, -73,-100, -90,  34, -20,  54, -61, -91, -98, -84,  28, -32, -80,  18, -97, -80; D=-8;
/I:         I=-8; DM=-16;
/M: SY='D'; M= -28, -94,  67,  48,-100, -83, -74, -99,  30, -97, -91,  -7, -83,   4,   5,  42, -21, -93,-104, -88; D=-8;
/I:         I=-8; DM=-16;
/M: SY='Q'; M=  28, -89, -89, -80, -78, -89,   8,  17,   1,  34,  32, -82, -91,  41, -27,   6, -18,  11, -95, -78; D=-8;
/I:         I=-8; DM=-16;
/M: SY='L'; M= -84,   6, -93, -93,  19, -98, -82,  18, -90,  75, -53,  34,-100, -87, -90, -88, -78, -15, -85,  18;
/M: SY='Y'; M= -35, -90, -80, -12,  11, -90, -71, -71,  19,  16,  31,  16, -90,  41, -15, -74,  34, -11, -77,  69;
/M: SY='K'; M= -31, -93,  12,  31, -93, -86, -74, -20,  59, -88,  -1,  10, -83,  20,  49,   1,  19, -84, -96, -83;
/M: SY='Y'; M= -89,-100, -89, -91, -37, -95, -55, -74, -83, -71, -68, -90,-101, -78, -80, -84, -83, -80,  31, 138;
/M: SY='Y'; M=  -2,   9, -91, -90,  45, -94,  42, -69, -86,  22,  19, -88, -98, -82, -83, -83, -81, -73, -60, 108;
/M: SY='P'; M=  36, -90,   9, -74, -94,  35,  29, -34, -23, -88,   7, -10,  38,  24, -16,  33, -72, -31, -97, -85;
/M: SY='Q'; M= -30, -97, -80, -65,   5, -89,  20,  -4, -24, -28,   1, -75, -89, 106, -67, -72, -20, -31, -78,  63;
/M: SY='L'; M= -84, -87,-102, -95, -59,-104, -87,  10, -96,  91, -47,-101,-101, -89, -93, -94, -80, -18, -89, -71;
/M: SY='C'; M= -29,  72,  13,  61, -17, -38,  10, -81,  17, -16, -79, -14, -85, -69, -75,  -4,  11,   8,-100, -83;
/M: SY='W'; M=  27,  17, -86, -81,  36, -23,   2, -73, -80,   5,  36, -16, -91,  42, -82,  20, -21, -19,  53,  42;
/M: SY='L'; M= -83, -89,-103, -96, -61,-104, -91,  56, -95,  74,  19, -99, -98, -89, -94, -93, -79,  11,  34, -71;
/M: SY='E'; M=  -7, -94,  42,  60, -81, -15, -74,  15, -72, -32, -77, -72, -83,  39, -77,   4, -18, -19, -88,  44;
/M: SY='L'; M=  20, -88,  -7, -74,  10, -15, -79, -74,  30,  31, -70,  13, -12,  26, -15,  -2,  20, -26, -92, -77;
/M: SY='R'; M= -81,  19, -76, -67, -95,  -5, -73, -99,  76, -94, -83,   0, -87, -60,  88, -75, -79, -93, -93, -83;
/M: SY='F'; M= -88, -90, -98, -16,  98,-101,  17,  38, -93,  32, -60, -93, -98, -94, -92, -90, -82, -21, -71, -50;
/I:         I=-5; MD=-9;
/M: SY='P'; M= -29, -99,  16, -77,   2,  26, -85, -25, -82, -13, -83,  16,  99, -83, -91, -27, -77, -88, -95, -88; D=-5;
/I:         I=-5; MD=-9;
/M: SY='M'; M=  19, -89,  33, -78,  22, -83,  11,  -3, -81, -78,  39,  28,  14, -80, -86,  34,   9,   9, -98, -78; D=-5;
/I:         I=-5; MD=-9;
/M: SY='D'; M= -29, -97,  56,  23,  -8,  32,  30,-100, -26, -97, -90,  11,  26, -10,   7,  14, -77, -96,-101, -85; D=-5;
/I:         I=-5; MD=-9;
/M: SY='C'; M=  21,  68, -20,  30, -93,  -7, -84,  -4, -20, -86, -82, -75, -87,  35,  -9,  25,  15, -13,-101, -89; D=-5;
/I:         I=-5; MI=0; MD=-9; IM=0; DM=-9;
/M: SY='Q'; M= -41,-110, -95, -17,  18, -15, -94,-102, -29, -41, -96,  15,-107,  34,  27,  -4, -21, -39,-108, -93; D=-5;
/I:         I=-5; DM=-9;
/M: SY='Q'; M= -92,-112, -89,  13,-112,  -6,  28, -23, -16,-105, -97, -86,-101,  60,  21,  10, -12,-103,-113, -97; D=-5;
/I:         I=-5; DM=-9;
/M: SY='M'; M=  -9,-104, -21, -99, -22, -27, -98,  32,  -8,  13,  51, -13,-105, -94, -98,   4, -89, -77,-107, -91; D=-5;
/I:         I=-5; DM=-9;
/M: SY='K'; M=  -8,  10, -79,  24,-105,  21, -86,-100,  50,-101, -92,  17, -11,  24, -23, -24, -83, -24,-104, -96; D=-5;
/I:         I=-5; DM=-9;
/M: SY='V'; M=  -7, -88, -97, -91, -70, -97, -92,  44, -90,  46,  30, -93,  35, -88, -93, -84, -11,  51, -95, -77;
/M: SY='E'; M=  -4, -93,  41,  59,   7, -85, -78, -17, -72, -45, -82, -15,  55,  -9, -80,  13,  11, -28, -96, -83;
/M: SY='F'; M= -90, -89,-102, -98, 118, -99, -85, -18, -94, -59, -68, -92, -12,-103, -93, -88, -10, -24, -61,   2;
/M: SY='T'; M=   9,  22, -73,  30, -89, -83,   7, -80, -21, -83,   6, -70,  23,   3, -78,  16,  80, -19,-101, -84;
/M: SY='W'; M= -93,-118,-119, -98, -57, -91,-116, -90, -89, -88, -90,-113, -97, -89, -93, -99,-105,-105, 180,   6;
/M: SY='Y'; M= -82, -93, -83, -81,  53, -89,  18, -80,  15, -76, -74, -17, -93, -73,  40,  20,  11, -81, -65,  95;
/I:         I=-13; MI=0; MD=-27; IM=0; DM=-27;
/M: SY='D'; M=  -4, -95,  93,   3, -92,  -8, -74, -91, -74,  -8, -86,  -7,  26,  -7, -81,   3, -74, -89,-101,   2;
/M: SY='A'; M=  60, -83, -14, -77, -91,   0, -84, -22, -78, -87, -81, -71,  25, -76, -85,  49,  55, -74, -98, -87;
/I:         I=-9; MI=0; MD=-19; IM=0; DM=-19;
/M: SY='Y'; M= -98,-107,-108,-102,  39,-110, -91, -82, -98,  25,  35,-102, -12,   1, -21,  -9, -16, -87, -90,  46; D=-9;
/I:         I=-9; DM=-19;
/M: SY='S'; M= -37,-102,  25, -87, -24,  27,   0, -23, -84,-101, -96,   6, -99, -85,  23,  41, -20, -38,-110, -94; D=-9;
/I:         I=-9; DM=-19;
/M: SY='F'; M= -32, -93, -87, -79,  59, -89,   7, -79,  17,  16, -74, -81,  43,  31, -22,  32,  -2, -80, -86, -69; D=-9;
/I:         I=-9; DM=-19;
/M: SY='S'; M= -22, -89,  12,  19, -94,   8, -78, -91,  25, -91,  16,  -9, -16,  -8, -74,  59,  43, -85,-100, -87; D=-9;
/I:         I=-9; DM=-19;
/M: SY='S'; M=  21, -96, -23, -27,-103,  33,  36,-102, -83,-102, -93,  -2,  12,  18, -88,  49, -17, -95,-106, -93; D=-9;
/I:         I=-9; DM=-19;
/M: SY='N'; M=  -7, -90, -11,   9, -83, -11,   2, -77,  31,   7,   2,  37,  20, -10,   1,   5, -22,   5, -94,  -5;
/M: SY='P'; M= -79, -95, -82, -14,  28,   7, -82, -81,  42, -14, -78, -79,  76, -74,  27,  -3, -24,  -5, -89, -79;
/M: SY='V'; M= -30, -87, -86, -15,  13, -32,  29,   1, -25, -11,   9, -81, -89, -82, -84, -22,  48,  54, -86,  45;
/M: SY='T'; M=  -9,   5, -78, -72, -91, -29, -79, -26,  25, -87, -80, -70,  24,  25,  43,  47,  52, -34, -97, -84;
/M: SY='Q'; M= -77, -96, -10, -64,  -6, -29,  11,   4, -66,   6, -71, -72, -88, 103,   9,  25, -76, -80, -88,  -7;
/M: SY='H'; M=  -4,  19, -22,  24, -86, -82,  73, -89, -24, -88, -80,  47, -85,  35,  19,  16,  18, -30, -97,  18;
/M: SY='S'; M=  -9, -84,  14, -73, -91,   1, -75, -89, -22, -41, -85,  57, -83, -70, -78,  80,  28, -84,-102, -85;
/M: SY='L'; M= -83, -89,-103, -96, -60,-104, -90,  46, -95,  82, -49,-100, -99, -90, -94, -94, -79,   0,  33, -71;
/M: SY='A'; M=  46, -88, -78,   8, -87, -81,  40, -16,  25, -16, -74, -74, -85,  21,  18,  29, -15,   5, -96, -80;
/I:         I=-11; MI=0; MD=-23; IM=0; DM=-23;
/M: SY='F'; M= -88, -91, -98, -96, 105, -27,  11,  -3, -92, -16, -67, -90,-100, -94, -90, -19, -83, -71,  34,  60;
/M: SY='E'; M= -77, -99, -48, 116,-101, -94, -71,-102, -59, -94, -90, -74, -73, -51, -69, -74, -78, -94, -98, -91;
/M: SY='K'; M= -82, -94, -77, -66, -83, -90,  45, -85,  86,  15, -73, -71, -86,  20,  38, -76, -18, -85, -89,   7;
/M: SY='A'; M=  72,  11, -88, -82,  27, -28, -85, -15, -81,  10,   1, -80, -88, -79, -14,  31, -71, -69, -89, -76;
/M: SY='C'; M= -28,  91, -73, -81,  12, -76, -75, -85, -77, -84,  43,  77, -91, -76, -82,  60, -17, -82,-101, -81;
/M: SY='V'; M= -73, -86, -98, -94, -70,-101, -98,  54, -91,  -5,   5, -91, -93, -91, -93, -81,  29,  83,-100, -77;
/M: SY='L'; M= -83, -88,-102, -96, -61,-104, -89,  52, -95,  79,  39, -98, -98, -88, -93, -93, -79, -12, -90, -72;
/M: SY='Y'; M= -88, -92, -94, -94,  95, -96,   4, -70, -88, -25, -68, -89,-100, -89, -86, -23, -18, -75, -55,  99;
/M: SY='N'; M= -78, -86, -58, -72, -92, -73, -64, -89, -65, -46, -83, 114, -88,  35,  -9, -62,  40, -89,-108, -86;
/M: SY='I'; M= -83,  11,-100, -96, -61,-103, -87,  75, -93,  58,  35, -94, -96, -88, -93, -90, -26, -49, -85,  33;
/M: SY='G'; M=  54, -87, -83, -86, -96,  83, -88, -92, -84, -93, -86, -71, -85, -81, -90,  -3, -17, -26, -93, -92;
/M: SY='A'; M=  67,  43, -86, -82, -81, -76, -85, -17, -82,  -6, -73, -78, -87, -78, -86,  48,  -9,  16, -94,  -2;
/M: SY='L'; M=  30,  19, -96, -90, -67, -93, -87,  34, -90,  61,  35, -90, -94, -86, -91, -80,   8,  -3, -90,  -7;
/M: SY='Y'; M= -33, -92, -92, -88,  10, -96,  56, -63, -26,  60,  11, -89, -98, -81, -82, -86, -81, -69, -69,  92;
/M: SY='S'; M=  23, -82, -75, -75, -87, -70,  18, -88, -75, -90, -84, -65, -82, -69, -80,  97,  29, -80, -96,   2;
/M: SY='Q'; M= -74,  36, -75, -22, -91, -83, -72, -83, -23,  -2,   9,  -2, -85, 100, -11,  34,  27, -83, -95, -80;
/M: SY='M'; M= -35, -89, -96, -90, -14, -97,   1,  51, -88,  49,  65, -89, -93,  -4, -88, -20, -10,   1, -86,  25;
/M: SY='A'; M=  93, -81, -85, -80, -95,  42, -87, -87, -81, -88, -81, -77, -84, -78, -87, -60, -72, -75, -93, -90;
/I:         I=-5; MI=0; MD=-11; IM=0; DM=-11;
/M: SY='A'; M=  50, -86, -81, -20, -25, -33, -83,   3,   2, -18, -75,  17, -87, -11, -24,  36,   0,   9, -96, -83; D=-5;
/I:         I=-5; DM=-11;
/M: SY='S'; M=  30, -89, -68,  43, -93, -78,  16, -88,   5, -88,   2,  31, -83,  38,  18,  50, -69, -27, -98, -83;
/M: SY='Q'; M=   4,   1, -72,  48, -85, -86,  14, -19,  -3, -29,  51, -16, -84,  74, -21,  -4, -16, -36, -91,   6;
/M: SY='D'; M= -26,  20,  58, -71, -87,  -7, -76,  -7, -74, -20,  36,  46, -18,  -4,   7,  23, -15,   1,-103, -84;
/M: SY='R'; M= -23, -93,  -9, -13, -15, -84, -71, -90, -15, -17, -80,  57,  17, -65,  84,  14, -74, -88, -96, -81;
/I:         I=-10; MI=0; MD=-22; IM=0; DM=-22;
/M: SY='E'; M=   6,-102,  24,  49,-101, -15,  34,-104, -14,-100, -92, -17, -90,  32,  12,  -3, -29, -98,-104, -10; D=-10;
/I:         I=-10; MI=0; MD=-22; IM=0; DM=-22;
/M: SY='T'; M= -13,  10,  23,   0, -94, -35, -82, -95,  11, -96, -90,  11, -89, -76,   8,  24,  61, -88,-104,   1; D=-10;
/I:         I=-10; DM=-22;
/M: SY='T'; M=  15, -96,  42,  30, -97, -90, -85, -88, -17, -18, -86, -76,  17,  21, -83, -20,  48, -26,-107, -92; D=-10;
/I:         I=-10; DM=-22;
/M: SY='E'; M=  32,  13,  64,  75, -98, -82, -75, -32, -69, -92, -88,  -3,  -1, -65, -77, -26, -21, -86,-103, -89;
/M: SY='G'; M=  16, -90,  35,   3, -98,  71, -79, -99, -75, -98, -90,  35, -84, -74, -10,  17, -23, -92, -98, -91;
/M: SY='L'; M= -33, -91,-100, -94,   9,-100, -84,  38, -92,  67,  12, -97, -11, -88, -91, -90, -80, -19,  45,  48;
/M: SY='K'; M= -24, -94, -73,  -1, -95, -87, -77, -90, 101, -92, -82, -68,  -4,   0,  -9, -73, -15, -22, -92, -84;
/M: SY='R'; M=  -5, -90, -19,  26, -88, -28,  19, -24, -22, -32,   7, -15, -84,  36,  49,  -5,  47,  -4, -98, -81;
/M: SY='A'; M=  86, -80, -82, -77, -92, -67, -84, -82, -79, -86, -80, -74, -83, -74, -83,  62, -64, -21, -95, -87;
/M: SY='C'; M=  17, 102, -94, -92,  31, -91, -87,  36, -89, -14,  31, -85, -95, -89, -92, -15,   8, -17, -87,  32;
/M: SY='H'; M=  16, -91,  27, -19, -90, -27,  49, -88,  29, -42, -81,  29,   9,  24,   7,  25, -16, -35, -97, -10;
/M: SY='Y'; M=  21,  15, -83, -83, -59, -87,  75, -28, -81,  14,   4,  23, -94, -11, -80, -77, -79, -76,  28,  93;
/M: SY='F'; M= -88, -88,-102, -97,  91,-101, -84, -10, -94,  61,   5, -96,-101, -95, -92, -91, -25, -63, -71,   3;
/M: SY='Q'; M= -13,  38, -76, -61, -95, -84, -71, -87,   7, -14, -75, -70, -86, 110,   2,  16,   4, -86, -93, -80;
/M: SY='Q'; M=  13,  42, -13, -19, -16, -85,   2, -84,  35,   1,   7,  15, -88,  76,  32, -72, -77, -83, -93, -78;
/M: SY='A'; M=  85, -79, -81, -76, -92, -67, -83, -85, -78, -87, -81, -73, -83, -73, -83,  63,   2, -73, -96, -87;
/M: SY='A'; M=  85, -81, -84, -78, -22, -70, -83, -79, -77, -81,  28, -76, -84, -75, -10,  39,  -9, -30, -93, -83;
/M: SY='G'; M= -11, -92, -80, -30, -96,  95, -86, -99, -83, -35, -88, -69, -85, -81, -25,   0, -17, -93, -92, -92;
/M: SY='C'; M=  20, 113, -98, -94, -78, -93, -96,  41, -91, -66,  43, -88, -97, -92, -95, -80, -74,  51,-103, -84;
/M: SY='F'; M=  -4, -88,-100, -95, 103, -97,  10, -63, -93,  27, -63, -92,-100, -95, -90, -87, -82, -17, -65,  39;
/I:         I=-12; MI=0; MD=-25; IM=0; DM=-25;
/M: SY='E'; M=  16, -91,  28,  49, -95, -81,   4, -91,  19, -40, -82,  25, -82,  45,  10,  15,  15, -86, -99, -84;
/M: SY='Y'; M= -87, -96, -90, -87,  60, -95,  59,   3, -82, -10, -67, -85, -97,   1, -18, -29, -82, -75,  45, 102;
/M: SY='L'; M= -25, -89,-102, -95, -62,-102, -89,  62, -94,  71,  47, -97, -96, -88, -93, -91, -78, -18, -90, -72;
/M: SY='N'; M=  -3, -89, -74, -75, -83, -80, -73,  23,  23, -17, -76,  63, -88, -68,  52,  47, -69, -76, -94,  -3;
/M: SY='E'; M= -76, -93,  47,  86, -97, -87, -73, -93, -65, -44, -86, -13, -77,  30, -73,   2,  41, -88,-101, -87;
/I:         I=-13; MI=0; MD=-27; IM=0; DM=-27;
/M: SY='N'; M= -31, -89, -22, -19, -89, -80,  11, -18,  19, -89, -82,  80, -87,  15, -14,  22,  37, -28,-101,  -3; D=-13;
/I:         I=-13; DM=-27;
/M: SY='F'; M= -83, -89, -94, -19,  99, -33, -84,  -3, -30, -61,   7, -15, -97, -92, -88, -23, -78,  39, -70,  11;
/M: SY='L'; M= -29,  19, -86,  -1, -18, -93, -83, -16, -26,  60, -61, -83, -11,   4,  13,   0,  33, -31, -92, -76;
/M: SY='H'; M= -80, -93, -68, -22, -89, -28,  99, -18, -13, -33, -77,  74,  38,  -3, -18,   2, -16, -89,-106, -75;
/M: SY='A'; M=  52, -84,   4,  14, -89, -76, -80, -16, -25, -35,   8,  -9, -83,   3, -79,  50,  30, -25, -98, -84;
/I:         I=-6; MD=-12;
/M: SY='L'; M= -99,  20, -13, -21, -16,-113,-102, -28, -33,  26,  -4, -20,-114,-101,-105,  -1, -95,  -2,-111,  -5; D=-6;
/I:         I=-6; MD=-12;
/M: SY='E'; M=-101,-119, -22,  38, -12, -33, -97,-119,   3,-116,-109,  -4, -17,  -6,  15,  -2, -98,-116,-117,-105; D=-6;
/I:         I=-6; MI=0; MD=-12; IM=0; DM=-12;
/M: SY='P'; M= -95,-119, -98, -87,-113, -98,-100,-102, -94, -44, -98,-102, 113, -96,-105, -20, -88,-106,-110,-111; D=-6;
/I:         I=-6; DM=-12;
/M: SY='S'; M= -23,  13, -92, -91,-102,  -1, -94, -99, -90, -20, -94, -82,   4, -86, -26,  73,   6, -94,-111, -98; D=-6;
/I:         I=-6; DM=-12;
/M: SY='P'; M= -12,-107, -26, -34, -98,-101, -95, -31, -89, -96, -92, -20,  31, -13,  11,  16,  -2,  19,-108,  13; D=-6;
/I:         I=-6; MI=0; MD=-12; IM=0; DM=-12;
/M: SY='D'; M= -82, -96, 112,  -8, -17, -30, -74, -21, -74, -92, -92, -58, -85, -73, -82, -26, -74,  -9,-112, -84;
/M: SY='M'; M= -81,   6,-101, -94,  18, -99, -84,  39, -91,  60,  92, -93, -95, -86, -90, -19, -77, -21, -88, -68;
/M: SY='S'; M=   5, -88,  58, -18, -95, -25,   3, -92, -71, -91,   7,   1, -83,  51, -76,  71, -14, -87,-102, -83;
/M: SY='P'; M=  17, -95, -16,  52, -94, -82, -75, -93, -24, -93, -84, -74,  64,  34,  33,  28, -22, -88, -93,  -5;
/M: SY='E'; M=  44, -88,  45,  53, -92, -77, -73, -90, -21, -89,  -4,  38, -82,  -2, -75,  14,   7, -83, -97,  -4;
/M: SY='T'; M= -73, -82, -79, -83,  14, -86, -82, -19, -79, -26,  48,  35, -84, -80, -84,   0,  89,  22, -98, -76;
/M: SY='L'; M= -79, -87, -97, -91,  -3,-100, -89,  37, -90,  60,  20, -91, -95,  -6, -91, -84,  26,  42, -92, -72;
/M: SY='K'; M=  -6,  38, -75, -25, -93,   8,   3, -92,  55, -36, -82,  15, -85,  17,  31,  44, -15, -87, -96, -84;
/M: SY='A'; M=  68,  51, -90, -85,  63, -25, -87, -74, -85, -16,   3, -82, -90, -85, -88,  -6,   7, -32, -84, -69;
/M: SY='L'; M= -84, -88, -98, -91,  -7,-100, -84, -12, -91,  82, -51, -13,-100,  -5, -90, -91, -80,  -2,  44,   6;
/M: SY='S'; M= -13, -88, -76,  28, -78, -84, -78,   8,  18, -17, -73,  -8, -86, -70,   8,  55, -18,  26, -90,  29;
/M: SY='S'; M= -10, -90,   6,   0, -87, -12,  39, -18,  35, -38,  15,  42, -84,  17, -20,  44, -20, -83, -96,  -8;
/M: SY='L'; M= -83, -88,-102, -95,  -8,-102, -85,  35, -93,  73,  66, -97, -98, -87, -91, -92, -79,   2, -86,   7;
/M: SY='M'; M=  -6,  59, -98, -91,  11, -92, -79, -58, -87,  30, 121, -88, -92, -82, -86, -31, -24, -21, -91, -70;
/M: SY='L'; M= -83,  21, -96, -90, -63, -99,  57, -19, -91,  79,  62, -91, -97, -84, -88, -89, -18, -61, -93, -69;
/M: SY='A'; M=  96, -81, -85, -79, -94,  27, -87, -86, -81, -87, -80, -78, -84, -78, -86, -60, -72, -73, -93, -90;
/M: SY='Q'; M= -22, -99,  -6,  61,-102, -86, -68, -92, -60, -34, -78, -70, -81, 115, -63, -69, -78, -92, -93, -82;
/M: SY='A'; M=  98,  20, -85, -78, -93, -67, -87, -84, -80, -85, -79, -79, -84, -76, -85,   6, -69, -71, -94, -89;
/M: SY='Q'; M= -35, -98, -72, -55,-102, -84,  58, -92, -61, -87, -75, -66, -84, 125, -61, -25,   8, -92, -93, -76;
/M: SY='E'; M= -78, -96, -55, 105, -92, -94, -73, -88, -63,   3,  17, -76, -76,   0, -71, -75, -10, -86, -96, -86;
/M: SY='C'; M= -29, 114, -95, -92, -76, -93, -90,  -3, -89,  21,  60, -84, -96, -89, -92, -31,  35,  17,-103, -83;
/M: SY='F'; M=  -4,  10,-100, -96,  86, -97, -88,  39, -93,   5, -62, -92, -97, -95, -93, -85, -17,  32, -74,  23;
/M: SY='W'; M= -84,  13,-104, -95,  48, -97, -96, -12, -92,  37, -65, -98, -98, -92, -93, -89,  -1,  31, 129,   2;
/M: SY='Q'; M= -32, -94, -76,  47,  29, -28, -75,  -3, -20,  23,   3, -78, -87,  75,  -9, -15, -78, -76, -84,   7;
/M: SY='K'; M= -80, -94, -12, -61, -96, -31,  14, -97,  99, -95, -83,  10, -82,  21,  12, -72, -22, -93, -93, -82;
/I:         I=-1; MD=-3;
/M: SY='A'; M=  52,  21, -90, -85, -84, -28, -88,  -6, -85,  17,  12, -82, -91, -13, -88,  45, -22,   6, -98, -85; D=-1;
/I:         I=-1; MD=-3;
/M: SY='I'; M= -80,  11,  -9, -90, -74, -97,   8,  50, -90,  35,  11,  -4, -95, -87, -92,  13,   4,  33,-101, -79; D=-1;
/I:         I=-1; MD=-3;
/M: SY='N'; M=  28, -90, -81,  -5,  31, -85, -80, -77, -22,  26,  25,  44, -13,  -8,   5,  15, -75, -78, -92, -76; D=-1;
/I:         I=-1; MD=-3;
/M: SY='D'; M= -26, -98,  70,  32,-104,  14, -77,-101, -20,-102, -94,  31,  41,  -3, -81,  16, -75, -98,-106, -93; D=-1;
/I:         I=-1; MD=-3;
/M: SY='G'; M=   7, -95,  36, -75,-101,  47, -83, -96,  39, -99, -91,  33, -17, -11, -77, -20, -10, -24,-103, -93; D=-1;
/I:         I=-1; MI=0; MD=-3; IM=0; DM=-3;
/M: SY='M'; M= -83, -94, -84, -21,   5, -93,   6, -77,  52,   0,  78, -17, -91, -71,  24,  -3, -10, -79, -85,  41; D=-1;
/I:         I=-1; DM=-3;
/M: SY='K'; M= -31,   5, -79, -70, -94, -37, -79, -89,  76, -31,  -2,  -6, -88,  15,  32,  20, -11, -28, -97, -85; D=-1;
/I:         I=-1; DM=-3;
/M: SY='D'; M=  27, -94,  63, -11, -85, -82,  36, -91, -77, -24, -84,  40,  16,  -6, -82,   2, -75, -89, -96,  41; D=-1;
/I:         I=-1; DM=-3;
/M: SY='S'; M=  22, -86, -84, -84, -14,  11, -86, -18, -83,  -1, -79, -73, -88, -78, -87,  75,  24, -34, -98, -83; D=-1;
/I:         I=-1; DM=-3;
/M: SY='L'; M= -82, -91, -97, -91, -69, -24, -89,  21,  -8,  70, -58, -92, -14, -86, -21,   8, -79,  -6, -94, -78; D=-1;
/I:         I=-1; DM=-3;
/M: SY='I'; M=  -2, -92,-101, -97,  -5,-101, -98,  78, -94,  10,  33, -93, -94, -92, -97, -86,  10,  29, -95, -76; D=-1;
/I:         I=-1; DM=-3;
/M: SY='A'; M=  81,   5, -87, -82, -94, -25, -89, -82, -83, -88, -82, -80,  -2, -80, -88,  40, -70,   1, -99, -91; D=-1;
/I:         I=-1; DM=-3;
/M: SY='K'; M= -83, -99, -78, -64,-100, -90, -76,-100,  89, -97, -85, -71,  -3,  32,  59, -15, -79, -96, -94, -85; D=-1;
/I:         I=-1; DM=-3;
/M: SY='L'; M= -24, -92, -94,  11, -68,-102, -89,  32, -92,  75, -55, -97,  -5, -86, -93, -32, -81, -60, -93, -78; D=-1;
/I:         I=-1; DM=-3;
/M: SY='A'; M=  70,  68, -87, -84, -94,   4, -88, -89, -84, -32, -84, -78, -90, -80, -89,  52, -70, -79,-100, -91; D=-1;
/I:         I=-1; DM=-3;
/M: SY='A'; M=  50, -91, -85, -80, -80, -37,   3,  -5, -27,   2,   9,  11,  -4,  33, -24,  13, -75, -76, -89,  37; D=-1;
/I:         I=-1; DM=-3;
/M: SY='Q'; M= -35, -98, -77, -65,-100,  -8, -75, -96,  38, -94, -83,   0,  -3,  97, -20,  14,   0, -94,  42, -83; D=-1;
/I:         I=-1; DM=-3;
/M: SY='V'; M=  16,  39, -93, -91, -81, -38, -97,   6, -89, -27, -70, -85, -93, -90, -93, -14,  49,  68,-105, -85; D=-1;
/I:         I=-1; DM=-3;
/M: SY='S'; M=  48,   4, -86, -83,  18,  20, -87, -83, -83, -42, -82, -77,  -4,   1, -88,  55, -21,  -6, -95, -82; D=-1;
/I:         I=-1; DM=-3;
/M: SY='E'; M=   4, -94,  42,  57, -90, -22, -77, -87, -73,   1, -83,  45,  -3, -70, -24, -27, -14, -34,-101, -12; D=-1;
/I:         I=-1; DM=-3;
/M: SY='Y'; M=  -9, -92, -93, -26,  61, -97,   3, -66, -90,  45,   3,  -6,-100, -87, -89, -86, -24, -32, -73,  68; D=-1;
/I:         I=-1; DM=-3;
/M: SY='Y'; M= -90,-100, -91, -93,  32, -97,  19, -78, -86, -74, -71, -90,-102, -82, -83, -17, -84, -82, -52, 127; D=-1;
/I:         I=-1; DM=-3;
/M: SY='Q'; M= -34,   7,  29,  37,-100, -11, -77, -98,  19, -96, -89, -15,  -3,  47,   4,  35,  15, -92,-102, -89; D=-1;
/I:         I=-1; DM=-3;
/M: SY='E'; M=  -6, -93,  35,  51, -98, -35, -77, -95,  22, -42, -88, -14, -83,  30, -73,  48,   5, -89,-102, -88; D=-1;
/I:         I=-1; DM=-3;
/M: SY='C'; M=  76,  86, -93, -87, -88, -79, -93, -77, -88,  -2, -77, -86, -94, -86, -92, -16, -74,   7,-101, -90; D=-1;
/I:         I=-1; DM=-3;
/M: SY='H'; M= -36,  34, -94, -89,  26, -40,  68, -24, -89,  28, -69, -86, -99,  17, -89, -25, -12,  18,  27,  26; D=-1;
/I:         I=-1; DM=-3;
/M: SY='K'; M=   3,-100,  38,  41,-104, -89,  13,-104,  47,-101, -93,  40, -89,  -8,  23, -77, -81, -99,-107, -91; D=-1;
/I:         I=-1; DM=-3;
/M: SY='M'; M=  14, -95,   2, -29,  41, -37,  -3, -18, -87, -29,  47, -11, -95,  -7, -89,  28, -19, -81,  34,  20; D=-1;
/I:         I=-1; MI=0; MD=-3; IM=0; DM=-3;
/M: SY='M'; M= -99,-113,   7, -32,  -9, -34,-102, -98,-102, -96,  66, -97, -13,  -3,-106,   7,  16, -40,-119,-100; D=-1;
/I:         I=-1; DM=-3;
/M: SY='W'; M=   3,-116,   4,  -6,-110, -41,-106, -10,   0, -39,-102, -98,-109, -15, -29,  -6, -21,-101,  42,-104; D=-1;
/I:         I=-1; DM=-3;
/M: SY='E'; M= -42,-116,   5,  37,-118,-109, -99, -28, -25,-110,-106,  15,-106,  14, -97, -20,   2, -28,-126,-110; D=-1;
/I:         I=-1; DM=-3;
/M: SY='A'; M=  47,  10,   5, -19,   3,  18, -87, -20, -84, -92, -87,   7,  11,  -5, -25, -22, -24, -85, -97,  -3; D=-1;
/I:         I=-1; DM=-3;
/M: SY='Q'; M= -37,-100, -22, -19, -96, -13, -81, -25, -77, -91,  -1,  42,  39,  63, -20,   3, -10,   0,-102, -10; D=-1;
/I:         I=-1; DM=-3;
/M: SY='V'; M= -36,  11, -91, -22, -84,  -6, -91,  16,  -5, -17,  12, -85, -95, -84,   0,  26,  15,  33,-101,  -5; D=-1;
/I:         I=-1; DM=-3;
/M: SY='S'; M=   6, -93, -82, -18, -97, -32,   7, -91,  30, -40, -86, -75,  -4,  -3, -17,  51,  39, -35,-104, -89; D=-1;
/I:         I=-1; DM=-3;
/M: SY='P'; M=  -1,-103,  22,  37,-105,  16, -87, -35,  14,-102, -94, -21,  71, -77, -84, -23, -82, -96,-104, -98; D=-1;
/I:         I=-1; DM=-3;
/M: SY='Y'; M=   1, -97, -90, -29, -15, -93, -79,  -7, -85,  -3, -76,   6, -98,  -7, -19,  19, -19,  -8,  37,  77; D=-1;
/I:         I=-1; DM=-3;
/M: SY='I'; M= -86,  15,-106,-105,  34,  23,-104,  69,-101, -14, -69, -96,-101,-100,-103, -92, -85,  24,  35, -76; D=-1;
/I:         I=-1; DM=-3;
/M: SY='P'; M= -89,-107,  42,  31,-109, -94, -82,-106,  26,-105, -96,  -7,  49,  25,  32,  -9, -84,-104,-108, -96; D=-1;
/I:         I=-1; DM=-3;
/M: SY='K'; M= -15, -99, -23, -82, -21, -93, -88, -86,  35,   9, -83, -83,  26, -80,  20,  30,   5, -31,-100, -14; D=-1;
/I:         I=-1; DM=-3;
/M: SY='N'; M= -16,-100,  36,  34, -22, -90, -81, -22,  22, -96, -92,  42, -93, -75, -24,  20, -79, -38,-103,   3; D=-1;
/I:         I=-1; DM=-3;
/M: SY='W'; M= -96,-113,-119,-102,  20, -99,-110, -82, -95,   4, -83,-113,-103, -95, -97,-102,-102, -32, 163,   9; D=-1;
/I:         I=-1; DM=-3;
/M: SY='I'; M= -16, -93, -92, -88, -14, -96, -93,  45,  12, -19, -71, -18, -10, -84,   8,   4,  20,  40,-100, -82; D=-1;
/I:         I=-1; DM=-3;
/M: SY='H'; M=  16, -95,   3, -78, -90, -87,  62, -92,  30, -19, -84,  26, -12, -76, -14,   9,  21, -89,-101,  15; D=-1;
/I:         I=-1; DM=-3;
/M: SY='H'; M= -24, -95, -92, -22,  -7, -98,  83,  23, -89,  26,  28, -86, -96, -83, -89, -25,  -1,   7,  44,  -3; D=-1;
/I:         I=-1; DM=-3;
/M: SY='M'; M= -10,  44,-101, -97, -76,-100, -95,  41, -94,  11,  68, -93, -97, -92, -96, -30,   8,  48,-102, -82; D=-1;
/I:         I=-1; DM=-3;
/M: SY='Q'; M= -30,   1, -75, -14,  -6, -85,  32, -90,  -2, -89, -82,  29,  -4,  69, -74,  25,  45, -87, -93,  25; D=-1;
/I:         I=-1; DM=-3;
/M: SY='M'; M=  33,  35, -93, -26,   5,   7, -91,  16, -89,   1,  52, -87, -93, -86, -92,   3, -76,  34, -96, -80; D=-1;
/I:         I=-1; DM=-3;
/M: SY='K'; M= -80, -96,  12, -58, -98, -87, -74, -97, 105, -95, -83, -65, -81,  31,   0, -74, -75, -93, -91, -83;
/M: SY='H'; M=  23, -90,  30, -69, -85, -81,  47,  -2,  30, -41,  35,  17, -86,  32, -16,  27, -71, -10, -96,  -8;
/M: SY='H'; M=  -8,  10,  -8,   1,   8, -87,  86, -82,  18,  13,   9,   9,  -9,  39, -22, -21, -78, -83, -93,  -1;
/M: SY='H'; M=  -7, -93, -87, -86,  50, -93,  93, -22, -85,  17, -64, -82, -96, -80, -82, -82, -82, -20, -69,  90;
/M: SY='F'; M= -89, -93, -94, -16,  94, -98, -72, -67, -88, -11,   9, -92, -11, -89, -87, -87, -83, -25, -58,  93;
/M: SY='Q'; M=  21, -89, -74,  28, -88,  -5, -77, -80,  26,   0,   8,   9, -84,  41,  19, -23,  35, -26, -95, -83;
/M: SY='A'; M=  78, -81, -82, -79, -87,  -4, -83, -79, -80, -84, -79, -74, -84, -75, -84,  54,  -7,   1, -92,   4;
/M: SY='V'; M=  21,  13, -95, -91,  -8, -92, -91,  32, -90,  43,   4, -13, -95, -87, -91, -16, -73,  55, -94, -75;
/M: SY='A'; M=  82,  18, -83, -79, -90,   1,  16, -24, -80, -83,   0, -75, -84, -76, -85,  25,  11, -72, -96, -85;
/I:         I=-1; MD=-2;
/M: SY='H'; M=   0, -96, -77, -19, -80, -87,  95, -86, -72, -30, -74, -72, -89,  84, -72,   4, -23, -25, -89,  52; D=-1;
/I:         I=-1; MI=0; MD=-2; IM=0; DM=-2;
/M: SY='Y'; M= -95,-104, -97, -99,  14,-103, -65, -77, -91, -15,  16, -97,-107, -87, -88, -92, -89, -82, -55, 124; D=-1;
/I:         I=-1; DM=-2;
/M: SY='R'; M= -32,-102, -87, -83,  43, -96,  65, -94, -69, -87, -82,   8,-100,   3,  69, -18, -86, -93, -85,  53; D=-1;
/I:         I=-1; DM=-2;
/M: SY='M'; M= -38, -96, -87, -82, -87, -93,  59,   4,  12, -10,  66,   8, -94,  43, -79,  11, -26,   7,-104, -80; D=-1;
/I:         I=-1; DM=-2;
/M: SY='A'; M=  61, -90, -89, -88, -98,  35, -91, -19, -88, -45, -87, -79, -91, -83, -92,  52, -74, -82,-101, -94; D=-1;
/I:         I=-1; DM=-2;
/M: SY='L'; M= -86, -97, -11, -22, -80,-100, -87,  11, -22,  49,   8, -87, -97,  24,  21,   1,  15, -72,-100, -83; D=-1;
/I:         I=-1; DM=-2;
/M: SY='H'; M=  29, -96,  18, -20, -92, -89,  73, -29, -81,  -6, -79, -78, -94,  35, -11,  14, -80,   6,-107, -82; D=-1;
/I:         I=-1; DM=-2;
/M: SY='C'; M=  15,  49,  30, -83,   9, -92, -87, -19, -88,  36, -74,  12, -99,  22, -91, -18, -11, -78,-101, -83; D=-1;
/I:         I=-1; DM=-2;
/M: SY='E'; M= -36,   9,   3,  64, -91, -32,   3, -33,   2,  22, -80, -14, -91, -73, -82,   1, -82, -29,-104, -89; D=-1;
/I:         I=-1; DM=-2;
/M: SY='E'; M=  -1,-103,  41,  71,-101, -92, -78,-103,   3, -99, -93, -76,  -9,  45, -75, -18, -82, -98,-101,   4; D=-1;
/I:         I=-1; DM=-2;
/M: SY='Q'; M=  19,-111, -92,   2,-116, -34,  27, -25, -22,-110,-102,  23,-106,  33, -94,   4, -93,-103,-120,-104; D=-1;
/I:         I=-1; DM=-2;
/M: SY='K'; M= -26, -98,  10, -74,-101,  23, -81, -99,  48, -34, -89,  24, -92,  32,  19,  15, -17, -96,-102, -91; D=-1;
/I:         I=-1; MI=0; MD=-2; IM=0; DM=-2;
/M: SY='K'; M= -84, -99, -75, -18, -99, -90, -77, -98,  84, -35, -85,  31, -88,  47,  23, -29, -79, -95, -97, -87; D=-1;
/I:         I=-1; DM=-2;
/M: SY='Y'; M= -88,   9, -93, -91,  41, -99,  45,  12, -88, -25,  16, -90,   6,  -3, -86, -87, -84,  -4, -67,  98; D=-1;
/I:         I=-1; DM=-2;
/M: SY='G'; M= -27, -96, -84, -93,-103,  97, -90,-108, -89,-105, -95, -71, -12, -86, -96,   3, -84,-101, -95, -97; D=-1;
/I:         I=-1; DM=-2;
/M: SY='E'; M= -38,-100,   5,  82, -96, -93,   2, -34, -72, -37, -88,  12, -12,  -3, -80, -17, -25, -26,  42, -88; D=-1;
/I:         I=-1; DM=-2;
/M: SY='A'; M=  51,   3, -79,  35, -99, -29,   7, -89, -74, -92, -85,  -3,  -2,  33,  11,  -1, -78,  -4,-102, -91; D=-1;
/I:         I=-1; DM=-2;
/M: SY='I'; M= -84, -96,-107,-102, -72,-110,-103,  77, -96,  20, -60,-100,-100, -96, -14, -94, -80,  53,-100, -81; D=-1;
/I:         I=-1; DM=-2;
/M: SY='A'; M=  61,  11, -88, -83, -99,  28, -89, -90, -26, -93, -87, -80, -13,   1,   8,  23, -77, -12,-100, -93; D=-1;
/I:         I=-1; DM=-2;
/M: SY='Y'; M= -36,  17, -18, -84,   6, -96,   5, -86, -13, -14,   6, -84,-100, -76,  62,  -4, -84, -86, -77,  81; D=-1;
/I:         I=-1; DM=-2;
/M: SY='L'; M= -89, -94,-105, -99,  14, -40, -89, -16, -95,  77, -56,-102,-106, -92, -12, -97, -86, -24, -89,   5; D=-1;
/I:         I=-1; DM=-2;
/M: SY='Q'; M= -31, -98, -21, -23,-100, -88, -77, -96,  43, -42, -85,  19, -89,  76,  32,   8,  15, -93,-100, -87; D=-1;
/I:         I=-1; DM=-2;
/M: SY='V'; M= -32, -96,  -2,   2, -20, -98,   7,  19,  23,  13,   5, -85, -13,  -2, -82, -24, -25,  29, -97,  -3; D=-1;
/I:         I=-1; DM=-2;
/M: SY='A'; M=  78, -87, -87, -83, -97, -29,  16, -88, -83, -91, -85, -80, -90, -79, -21,  43, -72, -20,-101, -90; D=-1;
/I:         I=-1; DM=-2;
/M: SY='L'; M= -12, -94, -84,  13, -83, -94,  16, -20, -20,  33,   2,  15, -13,  32, -84, -28,   8,  18,-102, -83; D=-1;
/I:         I=-1; DM=-2;
/M: SY='Q'; M=  13, -94, -14,  16, -99, -83,   3, -93,   6, -33, -85,  29, -12,  55, -76,  37,  17, -89,-103, -89; D=-1;
/I:         I=-1; DM=-2;
/M: SY='C'; M=  15,  46, -89,   0, -17, -93,  17,  -1,   0,  20, -74, -87,  -5,  13, -20,  -6, -82, -31,  35,   4; D=-1;
/I:         I=-1; DM=-2;
/M: SY='I'; M=  13,  42,-103, -98,  13,-100, -97,  47, -96,  32,  37, -96,-100, -94, -98, -87, -12,  21, -96, -78; D=-1;
/I:         I=-1; DM=-2;
/M: SY='N'; M= -36, -95,  22, -13,-100, -30, -77, -35,  61, -99, -90,  67, -89, -10, -67,  18, -12, -93,-105, -91; D=-1;
/I:         I=-1; DM=-2;
/M: SY='E'; M= -77, -97, -18,  72,-102, -10, -79,-101,   3, -99, -92,  -4, -83,  24, -75,  42,  20, -94,-104, -92; D=-1;
/I:         I=-1; DM=-2;
/M: SY='A'; M=  69, -88, -90, -84, -93,   7, -91, -30, -16, -12, -80, -82, -91,  -7, -87,  25, -75,  -7, -99, -91; D=-1;
/I:         I=-1; DM=-2;
/M: SY='Q'; M= -31, -95, -85, -28, -20, -11,   3, -23, -18,  28, -75, -17,  18,  36, -25,  28,  23, -80, -99, -83; D=-1;
/I:         I=-1; DM=-2;
/M: SY='K'; M= -82, -97, -16, -77, -21, -32,  16, -87,  54,  10,   9, -17,   7, -74,   2,  37, -23, -87,  32, -81; D=-1;
/I:         I=-1; DM=-2;
/M: SY='Y'; M= -11,   9, -16,  14, -20, -32,   2, -84,  18,  10, -79,  22, -93, -11, -18,  11, -10, -35, -93,  35; D=-1;
/I:         I=-1; DM=-2;
/M: SY='S'; M=  14, -94, -17, -79,  18, -31, -85, -89,  30, -20, -84, -78,  31, -78,   9,  38,  15, -86, -93,  -4; D=-1;
/I:         I=-1; MI=0; MD=-2; IM=0; DM=-2;
/M: SY='K'; M= -44,-123,-108,-100, -11, -17,  -1,-123,  34,-120,-112,-100, -11, -96,  20,   6,-103,-119,-120,-106; D=-1;
/I:         I=-1; DM=-2;
/M: SY='Y'; M=-107,-125,  42,-102,-104,  20,-102,-122,-108,-121,-116, -20,-118,-106,-114, -25, -30,-121,  22,  45; D=-1;
/I:         I=-1; DM=-2;
/M: SY='V'; M=  -3,   1,  -1,-104,  16,-114,-107, -35,-104,  -3, -90,-106,-117,  -8, -16,-101, -29,  17,-111, -12; D=-1;
/I:         I=-1; DM=-2;
/M: SY='N'; M=  11,-111, -98,-104, -98, -40, -96,-102,-100,-108,-102,  49, -14, -98,-105,  11, -92, -11,  26,  37; D=-1;
/I:         I=-1; DM=-2;
/M: SY='D'; M= -99,-114,  35, -25,-100, -42, -97, -97,  -4, -10, -97, -20,  18, -94, -32,  -9, -95,  -6,-113,  15; D=-1;
/I:         I=-1; DM=-2;
/M: SY='W'; M=  -3,-109, -19,  16,   3,-103, -96,-100,   2, -47, -97, -20,-104, -88,   2,  -1,   0, -39,  36,  -1; D=-1;
/I:         I=-1; DM=-2;
/M: SY='V'; M= -97,-109,  30,  -3, -91,-114,-102, -74,-102,  11,  14,-102, -10,-100,-106,-102, -93,  47,-115,  -4; D=-1;
/I:         I=-1; DM=-2;
/M: SY='Q'; M= -37,-110,-100,  -6,  11,-111, -95,  -3, -94,   3, -84,   5,-111,  35, -20, -98, -96,   5,-100,  27; D=-1;
/I:         I=-1; DM=-2;
/M: SY='D'; M= -10,-110,  43,  41, -25, -44, -98,  -9, -92,-100,-100, -89,-101, -89,-100, -25,   7, -10,-118,-101; D=-1;
/I:         I=-1; DM=-2;
/M: SY='D'; M= -34,-108,  68,   2,-104, -33, -91,  10, -17, -21, -95,  26,-100, -87, -94, -87, -14, -92,-119,-100; D=-1;
/I:         I=-1; DM=-2;
/M: SY='L'; M= -90, -98,-105,-100,   6,-108, -93, -19, -99,  48, -68,-101,-107, -11, -99, -23,   5,  28, -93,  38; D=-1;
/I:         I=-1; DM=-2;
/M: SY='Q'; M= -35,-102,  17, -13,-101, -94, -87, -96,  39, -43, -91,  10, -95,  40, -16,   5,  21, -27,  34, -92; D=-1;
/I:         I=-1; DM=-2;
/M: SY='G'; M= -16,-104,   7, -23,  31,  46, -91, -97,   3, -96, -92, -84, -14,  -6, -27, -83, -19, -27, -94,  16; D=-1;
/I:         I=-1; DM=-2;
/M: SY='F'; M= -33,-102,-106, -98,  53,-108,  27,  26, -98,  36, -70, -99,-106,  28, -97, -95, -20, -74,  35, -71; D=-1;
/I:         I=-1; DM=-2;
/M: SY='K'; M= -15,-102, -88,   6,  -9, -39,   9, -27,  56, -19,   7, -85, -96, -78, -16,  -4, -24, -37, -99,  -4; D=-1;
/I:         I=-1; DM=-2;
/M: SY='D'; M=   2,-101,  64,  12,-109, -31, -86,-106, -25,-107,-101,  14, -12, -80, -27,  27,   1,-100,-116, -99; D=-1;
/I:         I=-1; DM=-2;
/M: SY='V'; M=   3, -96, -91,   1, -94, -97, -96, -75,   3, -37, -83, -88, -97, -84,  12,  20,  26,  47,-110, -93; D=-1;
/I:         I=-1; DM=-2;
/M: SY='I'; M= -32,  53,-112,-107, -80,-112,-109,  54,-105,  20, -68,-105,-108,-104,-107, -97, -85,  50,-109, -89; D=-1;
/I:         I=-1; DM=-2;
/M: SY='Q'; M= -80, -98, -76,  23,-101,   4, -82, -97,  24, -37, -89,  28, -12,  38, -15,  32,  27, -94,-104, -92; D=-1;
/I:         I=-1; DM=-2;
/M: SY='E'; M=   9, -96,  20,  52,  -8, -30,  13,  -8,  -1, -90, -86, -75, -87, -70,  11,  33, -25, -33,-101, -85; D=-1;
/I:         I=-1; DM=-2;
/M: SY='K'; M=  15, -95,  38, -12, -95, -88, -81, -90,  54, -15,  13, -73, -88, -11,  17,   0,  20, -86,-101, -87; D=-1;
/I:         I=-1; DM=-2;
/M: SY='L'; M= -87, -93, -95, -29, -69,-103,   9, -63,  -8,  76, -58, -93,-100,  21, -86, -90,   1, -69, -93,  -2; D=-1;
/I:         I=-1; DM=-2;
/M: SY='K'; M=   7, -94,  21,  36,  -9, -86, -75, -96,  71, -94, -86,  29, -84,  -9,  23, -73, -23, -91, -96, -84; D=-1;
/I:         I=-1; DM=-2;
/M: SY='R'; M=  -7, -92, -19,  13, -95, -30,   0, -91, -21, -91, -84,  -2, -86,  35,  63,  41,  31, -34,-100, -84; D=-1;
/I:         I=-1; DM=-2;
/M: SY='A'; M=  71, -84, -81, -22, -86, -76, -81, -77, -79,  23,   2,  35, -88,  13, -83,   7, -22, -73, -97, -85; D=-1;
/I:         I=-1; DM=-2;
/M: SY='E'; M= -36, -95, -64,  77, -91, -91, -77,   8,  18, -19, -78,  42,  -9,  20, -72, -76, -76,   6, -99, -87; D=-1;
/I:         I=-1; DM=-2;
/M: SY='K'; M= -83, -96, -76, -66, -94, -90,  11, -34,  93, -38, -81,  -8, -12, -62,  46, -76, -11, -89, -94, -83; D=-1;
/I:         I=-1; DM=-2;
/M: SY='D'; M= -37,   1, 116,  -7,-105, -84, -74,-103, -74,-102,-100, -57, -86, -73, -83, -74, -19, -99,-120, -90; D=-1;
/I:         I=-1; DM=-2;
/M: SY='N'; M= -82, -88, -58, -75, -93, -73,  10, -92,  21, -25, -85, 118, -92, -69, -71, -66, -68, -94,-111, -88; D=-1;
/I:         I=-1; DM=-2;
/M: SY='D'; M= -84, -99, 115,   6,-106, -83, -72,-104, -73,-103,-101,  -6, -85, -71, -82,  -6, -75,-101,-119, -90; D=-1;
/I:         I=-1; DM=-2;
/M: SY='F'; M= -89, -93,-100, -91,  82,-100, -83, -64, -88,  45,   0, -95,-101,  30, -27, -90, -85, -19,  66,  34; D=-1;
/I:         I=-1; DM=-2;
/M: SY='I'; M= -81, -94,-105,-101, -69,-107,-101,  96, -97, -12,  38, -96, -94, -93, -99, -92, -77,  39, -95, -76; D=-1;
/I:         I=-1; DM=-2;
/M: SY='Y'; M= -90, -99, -89, -17,  42, -98,  20, -74, -85, -71, -70, -90,-101, -81, -83, -86, -84, -27, -52, 125; D=-1;
/I:         I=-1; DM=-2;
/M: SY='H'; M= -86, -95,   1, -78, -77, -94, 115, -75, -21,  49, -64, -15,  -4, -75, -16, -83, -83, -27,-105, -67; D=-1;
/I:         I=-1; DM=-2;
/M: SY='Q'; M=   6, -97,  67,  39,-102, -84,  27, -99,  26, -95, -87, -16, -84,  73, -68, -20, -77, -94,-102, -85; D=-1;
/I:         I=-1; MI=0; MD=-2; IM=0; DM=-2;
/M: SY='H'; M= -31, -97, -82,  27, -86, -92,  52,  28, -22,   0,  27, -82,  51, -75,  10,  23, -78, -31,-100, -82; D=-1;
/I:         I=-1; DM=-2;
/M: SY='V'; M= -78, -92, -99, -17, -76,-105,-102,  49, -94, -16, -64, -98,  25, -94, -97, -89, -75,  82,-103, -83; D=-1;
/I:         I=-1; DM=-2;
/M: SY='P'; M= -84,-108, -85,  -4,-102, -90, -89, -18, -82, -97, -87, -90, 116,  -6, -92, -24, -19, -27,-101, -99; D=-1;
/I:         I=-1; DM=-2;
/M: SY='P'; M=  23, -97,   9, -73,-104, -13, -83, -99,  39,-101, -91,  12,  41,  32, -75,  39, -75, -94,-103, -94; D=-1;
/I:         I=-1; DM=-2;
/M: SY='E'; M= -31, -98,   3,  41, -15, -96,  14, -77,  -8,  14, -78, -84,  16,   2, -24,  -4, -19,  23,-102, -85; D=-1;
/I:         I=-1; DM=-2;
/M: SY='S'; M=   3, -91, -15, -15, -89, -22, -84,  -6,  15, -33, -79,  13, -89, -75,  24,  38,  16,  26,-102, -86; D=-1;
/I:         I=-1; DM=-2;
/M: SY='Q'; M=   8, -93,  26,  34,-100, -83, -80, -94, -21, -95, -88, -71,  26,  49, -78,  45,  41, -88,-103, -90; D=-1;
/I:         I=-1; DM=-2;
/M: SY='L'; M= -27,   9,-107,-100,  20,-107, -94, -21, -98,  74, -58,-104,-107, -95, -23, -97, -86,  -5, -94, -75; D=-1;
/I:         I=-1; DM=-2;
/M: SY='P'; M=  14,-102,  31,  -3,-105,  -6, -86, -98,  21, -99,  13, -80,  75,  -5, -82,   0, -80, -95,-104, -97; D=-1;
/I:         I=-1; DM=-2;
/M: SY='P'; M=  12, -98,  15,  -3, -97, -88, -89, -31, -20, -17, -86, -81,  65, -81, -27,  29,  17, -31,-105, -94; D=-1;
/I:         I=-1; DM=-2;
/M: SY='I'; M= -86, -96,-107,-103,  -7,-110,-104,  77,-100,  19, -62, -99,-100, -99,-102, -93,   7,  38, -99, -79; D=-1;
/I:         I=-1; MI=0; MD=-2; IM=0; DM=-2;
/M: SY='K'; M=  -9,-101,  32,   1,-102, -32, -87, -31,  59, -96, -90, -12,  12,  -6, -72, -20, -19,  -3,-106, -94; D=-1;
/I:         I=-1; DM=-2;
/M: SY='P'; M= -16,-103, -85, -23,-104,  18, -88,-100,  41, -48, -92,   7,  64, -79,  19, -80,   8, -97,-103, -97; D=-1;
/I:         I=-1; DM=-2;
/M: SY='M'; M=  41, -93, -29, -90, -83, -94, -93, -68,  17,  35,  56, -93, -99, -87, -87, -85, -82,  23,-102, -86; D=-1;
/I:         I=-1; MI=0; MD=-2; IM=0; DM=-2;
/M: SY='D'; M= -79,  -1,  54, -18, -95, -29, -82, -86, -78, -18,   7, -16,  26,  35, -24,  37,  11,  -9,-107, -89; D=-1;
/I:         I=-1; DM=-2;
/M: SY='M'; M=  34, -90, -99, -92, -77,  -6, -86, -24, -91,  33, 100, -91, -19, -85, -91, -29, -80, -22, -97, -80; D=-1;
/I:         I=-1; DM=-2;
/M: SY='V'; M=  21, -90, -97, -93, -82,   3,-100,  12, -20, -29, -70, -90, -96, -91, -93, -15, -22,  75,-104, -86; D=-1;
/I:         I=-1; DM=-2;
/M: SY='K'; M= -17, -98, -10, -66,-101, -90, -80, -96,  91, -97, -87, -16,  -7,  27,  -5, -77, -17, -38, -97, -88; D=-1;
/I:         I=-1; DM=-2;
/M: SY='P'; M=  35,  43, -89, -82, -95, -84, -91, -30, -16, -35, -84, -85,  78, -84, -90,  34, -22,  -7,-102, -94; D=-1;
/I:         I=-1; DM=-2;
/M: SY='I'; M= -85, -97, -18, -88, -80, -99,  46,  66, -34,   6, -68, -11,  24, -86, -27, -27,  33, -25,-102, -81; D=-1;
/I:         I=-1; DM=-2;
/M: SY='P'; M= -40, -96, -89, -28, -86, -95,  17, -25,  -6,  22, -73, -88,  75, -85, -88, -27,  31,  24,-102, -87; D=-1;
/I:         I=-1; DM=-2;
/M: SY='W'; M= -87,-100, -12, -87,   9, -98, -93,  21, -26,  23,   9, -93,  63, -13, -29, -29, -83,   9,  73, -77; D=-1;
/I:         I=-1; DM=-2;
/M: SY='Q'; M= -10, -99,  37,  35,-100, -35, -78, -94, -69, -35, -87,  29,  29,  46,  33,  -8, -79, -32,-104, -91; D=-1;
/I:         I=-1; DM=-2;
/M: SY='E'; M=  20, -95,  36,  48, -98, -88, -82, -88,  32, -41, -86, -16, -10,  12, -74, -27,   5,  -2,-104, -91; D=-1;
/I:         I=-1; DM=-2;
/M: SY='I'; M= -84, -95, -10, -87, -17,-100, -90,  39, -18,  35,  32, -18,  14,  13, -89, -31, -18,  25, -98, -80; D=-1;
/I:         I=-1; DM=-2;
/M: SY='Y'; M=  20,-113,-108,  -6, -23,-111,-101, -96, -34, -20,  -1,-108,-114,-101,-105, -98,   2, -25,-102,  48; D=-1;
/I:         I=-1; DM=-2;
/M: SY='Q'; M= -20,-122, -30,   4,-122,  16,  -4,-118,  12, -52,  -2, -99, -17,  21, -97, -99,-106,-116,-122,-112; D=-1;
/I:         I=-1; MI=0; MD=-2; IM=0; DM=-2;
/M: SY='K'; M= -38,-103, -91, -86,-101, -32, -92,  -5,  32, -93,   7,   8,  18,  12,   3,   9,   1,   6,-109, -96; D=-1;
/I:         I=-1; DM=-2;
/M: SY='K'; M=  12,-101, -18,  14, -22, -13,   2, -30,  25, -95, -90, -83, -17, -80,  18,   3,   3, -10,-106, -92; D=-1;
/I:         I=-1; DM=-2;
/M: SY='K'; M= -32,-100,   3,  11, -88, -99,   1,  -1,  25,   4,  13, -18,   9,  -6, -82, -85,   9,   9,-103, -11; D=-1;
/I:         I=-1; DM=-2;
/M: SY='K'; M= -86, -99,  10, -81, -23, -31, -88,  -8,  33,   7, -80,   8, -96,  16,   2,  -2,  17,  -2,-104, -87; D=-1;
/I:         I=-1; DM=-2;
/M: SY='G'; M= -84,  48,  25, -24,  10,  49, -86,-100,  16, -96,   7, -15, -97, -85, -87,  -7, -86, -98, -94,  32; D=-1;
/I:         I=-1; DM=-2;
/M: SY='P'; M= -86,-102,   8,  15, -98, -32, -86,  -7, -79, -20, -86,  24,  46,  19,   7,  -6,  23, -31,-108, -94; D=-1;
/I:         I=-1; DM=-2;
/M: SY='D'; M=  10, -94,  85,  -1, -96, -33,  53, -21, -27, -92, -86,  28,  28, -72, -79, -26, -19, -34,-108, -84;
/M: SY='L'; M=  -6, -87,-100, -94,   8, -24, -89,  34, -94,  74,  13, -95, -97, -89, -93, -88, -79,   1, -88, -70;
/M: SY='F'; M= -89, -89, -97, -18, 112, -98, -80, -66, -92,   8, -66, -92,-100, -95, -90, -17, -82, -71, -61,  42;
/M: SY='R'; M=  35, -90, -78, -19, -92, -22, -78, -84,  42, -44, -79, -15,  25,  13,  48,  12,   4,  -8, -95, -85;
/M: SY='N'; M=  -6, -92,   6,  19, -91,  24, -73, -92,  53, -93, -85,  57, -85, -65,  35, -13, -74, -30, -94,   5;
/M: SY='L'; M= -83, -88,-102, -96,  20,-104, -90,  47, -95,  74,  12, -98, -99, -91, -94, -92, -78,  20, -87, -68;
/M: SY='V'; M= -21,  41, -98, -93, -70, -98, -95,  30, -92,  38, -58, -92, -96, -91, -93, -17, -17,  75, -99, -78;
/M: SY='P'; M= -82,   0, -85, -75, -97, -86, -87, -25, -79, -39, -83, -88, 122, -83, -26, -24, -10, -88, -97, -96;
/M: SY='M'; M=   4,  22, -94, -88,  25, -92, -81,  37, -84,  -2,  71, -86, -93,  -6, -17,   7, -74,  26, -81,  48;
/I:         E1=0; IE=-105; DE=-105;
/M: SY='A'; M=  56, -87,  24,  29, -90,  -6,  43, -84, -75, -12, -79,  11, -84,  -2, -80,  20, -16, -30, -99, -83;
/M: SY='V'; M=  -4, -86,  -9, -88, -12, -94, -94,  37, -88, -11, -62, -87, -93, -15, -91,   7, -69,  82, -98, -77;
/M: SY='H'; M= -82, -94, -76,  18,  16, -91, 100,  -2, -13, -11,  38, -13, -88,  41, -73, -76,   6, -30, -89,  35;
/M: SY='E'; M= -79, -97,  20,  83, -91, -91,  37, -35, -62, -36, -81,  -7, -81,  50,  19, -73, -13, -35, -96,  -1;
/M: SY='S'; M=  56, -84, -81, -76,  -4, -75, -78, -78,  11, -19, -76, -13, -86,  -1, -21,  59, -67,  -7, -87,  26;
/M: SY='M'; M=  29,  39, -77,  35, -82,  -4, -79, -75, -76,  26,  41,   0, -87,   4, -25,  28, -14, -31, -96, -82;
/M: SY='S'; M=  10, -85,  -4, -69, -92, -74, -76, -85, -12, -44, -81,  -5, -83,  60, -74,  80,  26, -26, -98, -83;
/M: SY='A'; M=  47, -86, -90, -83, -15, -85, -86,  40,  20,  31,   6, -83, -89, -79, -81,   7, -22,   0, -89,  -5;
/M: SY='Y'; M= -29, -96, -90, -91,  33, -93, -60, -12, -84, -68,   7, -88, -99, -80, -82, -20, -81, -75, -50, 127;
/M: SY='S'; M=  11, -85,  27,  21, -94, -73, -73, -92, -69, -94, -87,  56, -83, -66,   5,  75,   9, -85,-103, -86;
/M: SY='E'; M= -27, -97,  12,  99, -97, -27, -72, -26, -62, -35, -84, -73, -77,  49, -70, -73, -78, -88, -97, -88;
/M: SY='E'; M= -81,  16, -66,  74, -90, -93,  41, -91,   8, -13,  18, -12, -84, -59,  72, -77, -80, -88, -97, -81;
/M: SY='K'; M= -78,  13,  10,  -6, -97, -87, -74, -91,  83, -91, -81, -67, -83,  73,   6, -18, -11, -28, -94, -83;
/M: SY='D'; M=  63, -87,  76,   4, -97, -75, -78, -92,   7, -92, -87, -66, -83, -70, -15,  17, -19, -83,-102, -87;
/M: SY='E'; M= -75, -92, -10,  54, -94, -85, -74, -18,  52, -88, -81,   2, -81,  48,   4,  27,  24, -25, -97, -84;
/I:         E1=0; IE=-105; DE=-105;
/M: SY='Y'; M= -25, -90, -97, -93,  16, -98, -78,  38, -91,  58,  11, -93, -97, -86, -89, -18, -78, -13, -74,  74;
/M: SY='V'; M=  -4, -85, -99, -92,  -1, -97, -93, -11, -92,  54, -56, -94, -97, -90, -92, -17, -72,  75, -94, -74;
/M: SY='R'; M= -80, -95,   0,  25, -93, -86, -69, -95,  -8, -29, -82,  45, -88,   0,  93,   8, -76, -91, -97, -82;
/M: SY='Q'; M=  32, -90,  31,  37, -96,   3, -74, -92,   4, -90,  14,  31, -83,  43,  11,   9, -15, -86, -98, -86;
/M: SY='E'; M= -17,  10, -68,  70, -84, -23,  47, -20, -18, -10,  46, -75, -83,  -2,  26,   3, -77, -81, -93,   2;
/M: SY='V'; M= -30, -89, -10, -17,  33, -24, -86,  45, -17, -30,  16,   2, -90,   4, -84,   4, -10,  49, -91, -72;
/I:         I=-14; MI=0; MD=-29; IM=0; DM=-29;
/M: SY='E'; M=  17, -92,  48,  60, -98,  -2, -76, -93,  -6, -94, -89,  36, -83, -67, -77,  21, -14, -23,-104, -90; D=-14;
/I:         I=-14; DM=-29;
/M: SY='P'; M=  -2, -97, -13,  42, -94, -87,  12, -12,  25, -38, -80, -75,  68,  29,  40,  -8, -76, -85, -95, -85;
/M: SY='I'; M= -77, -88, -95, -90,  -9, -97,   8,  54, -86,  33,  44, -87, -92, -85, -11,   5,   9,  46, -94, -72;
/M: SY='E'; M= -26, -95,  52,  80, -98, -21, -72, -95,  15, -93, -88,   4, -80,   1,  16, -19, -75, -25,-100, -88;
/M: SY='S'; M= -23,  29,  -6,  27, -85, -82, -78, -75, -73,   5, -76,  37, -86,  -3,  -7,  50,  35,  16,-101, -83;
/M: SY='A'; M=  58,  19, -89, -82, -74, -20, -81, -69, -16,  42,  54, -82, -90,   6, -82,   3, -74, -69, -88,  12;
/M: SY='N'; M= -77, -87,  61, -17, -94, -19, -69, -91, -70, -95, -87,  95, -84, -71, -78, -62,  63, -88,-111, -88;
/M: SY='W'; M= -76, -94, -16,  38, -89,  34, -78, -13,  46, -37,   8,  21, -83,  31, -69, -21,  16, -85,  65, -81;
/M: SY='E'; M= -78, -94, -69,  71, -82, -93,  25, -20,  24,  34,  12, -77, -83,  47, -69, -17, -77, -19, -94, -79;
/M: SY='M'; M=   0, -88, -96, -90, -61, -17, -77, -16, -18,  59,  87, -90, -94, -81, -85, -85, -79, -20, -81,  53;
/I:         E1=0; IE=-105; DE=-105;
» More

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2014_04 which contains 544'996 sequence entries.


Total number of hits 61 in 61 different sequences
Number of true positive hits 61 in 61 different sequences
Number of 'unknown' hits
Number of false positive hits
Number of false negative sequences 0
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 100.00 %

Comments [info]

Matrix type [info] protein_domain
Scaling database [info] reversed
Author [info] PS_Langendijk_Genevaux
Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 1
Feature key [info] DOMAIN
Feature description [info] BRO1
Version [info] 2

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
61 sequences

ALIX_DICDI  (Q8T7K0), ALX1_CAEEL  (P34552), BRO1_ASHGO  (Q74ZJ6), 
BRO1_ASPFU  (Q4X0Z5), BRO1_CANAL  (Q5AJC1), BRO1_CANGA  (Q6FJG8), 
BRO1_CRYNB  (P0CM45), BRO1_CRYNJ  (P0CM44), BRO1_DEBHA  (Q6BRL3), 
BRO1_EMENI  (C8V212), BRO1_GIBZE  (Q4IBS9), BRO1_KLULA  (Q6CM12), 
BRO1_NEUCR  (Q7SAN9), BRO1_SCHPO  (O13783), BRO1_USTMA  (Q4PHA8), 
BRO1_YARLI  (Q6CGJ5), BRO1_YEAST  (P48582), BROX_CAEEL  (Q22885), 
BROX_DANRE  (A3KQV2), BROX_HUMAN  (Q5VW32), BROX_MOUSE  (Q8K2Q7), 
BROX_PONAB  (Q5RDD7), BROX_RAT    (Q4V8K5), BROX_XENTR  (A4IIL4), 
PALA_ASHGO  (Q756C5), PALA_ASPOR  (Q5KU05), PALA_CANAL  (Q9UW12), 
PALA_CANGA  (Q6FKK0), PALA_CRYNB  (P0CM47), PALA_CRYNJ  (P0CM46), 
PALA_DEBHA  (Q6BLT2), PALA_EMENI  (P79020), PALA_KLULA  (Q6CU63), 
PALA_MAGO7  (Q51NJ3), PALA_NEUCR  (Q7S532), PALA_SCHPO  (Q09807), 
PALA_YARLI  (Q8WZL4), PALA_YEAST  (Q12033), PALC_CRYNB  (P0CM49), 
PALC_CRYNJ  (P0CM48), PALC_EMENI  (Q9P905), PALC_MAGO7  (Q524Z5), 
PALC_NEUCR  (Q7SEM8), PALC_YARLI  (Q6C1E4), PDC6I_HUMAN (Q8WUM4), 
PDC6I_MOUSE (Q9WU78), PDC6I_RAT   (Q9QZA2), PDC6I_XENLA (Q9W6C5), 
PTN23_HUMAN (Q9H3S7), PTN23_MOUSE (Q6PB44), PTN23_RAT   (O88902), 
RHN2A_XENLA (Q6DJJ6), RHN2B_XENLA (Q63ZR5), RHN2P_HUMAN (A8MT19), 
RHPN1_HUMAN (Q8TCX5), RHPN1_MOUSE (Q61085), RHPN2_BOVIN (A4FUC9), 
RHPN2_CANFA (Q8HXG3), RHPN2_DANRE (Q6TNR1), RHPN2_HUMAN (Q8IUC4), 
RHPN2_MOUSE (Q8BWR8)
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PDB
[Detailed view]
19 PDB

1ZB1; 2OEV; 2OEW; 2R02; 2R03; 2R05; 2XS1; 2XS8; 3C3O; 3C3Q; 3C3R; 3R9M; 3RAU; 3ULY; 3UM0; 3UM1; 3UM2; 3UM3; 3ZXP
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