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Entry: PS51183

General information about the entry

Entry name [info] JMJN
Accession [info] PS51183
Entry type [info] MATRIX
Date [info] 01-FEB-2006 CREATED; 10-MAY-2017 DATA UPDATE; 22-NOV-2017 INFO UPDATE.
PROSITE Doc. [info] PDOC51183
Associated ProRule [info] PRU00537

Name and characterization of the entry

Description [info] JmjN domain profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ABCDEFGHIKLMNPQRSTVWYZ'; LENGTH=42;
/DISJOINT: DEFINITION=PROTECT; N1=5; N2=38;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=2.0609195; R2=0.0138589; TEXT='NScore';
/NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=2398.1782227; R2=1.2883356; PRIORITY=1; TEXT='Heuristic 5.0%';
/CUT_OFF: LEVEL=0; SCORE=465; H_SCORE=2997; N_SCORE=8.5; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=321; H_SCORE=2812; N_SCORE=6.5; MODE=1; TEXT='?';
/DEFAULT: M0=-9; D=-50; I=-50; B1=-500; E1=-500; MI=-105; MD=-105; IM=-105; DM=-105;
...
                A   B   C   D   E   F   G   H   I   K   L   M   N   P   Q   R   S   T   V   W   Y   Z
/I:         B1=0; BI=-105; BD=-105;
/M: SY='I'; M= -2,-21, -8,-30,-25, -6,-30,-25, 26,-24,  7,  8,-13,-22,-20,-25,-12, -7, 20,-26, -9,-25;
/M: SY='P'; M= -9,-21,-34,-14, -4,-22,-22,-19,-10,-13,-14,-10,-21, 56, -9,-18,-12, -9,-17,-28,-23,-10;
/M: SY='V'; M= -1,-17,-15,-20,-14, -7,-24,-20,  9,-10,  1,  5,-16,-20,-14, -8, -3,  7, 20,-27,-10,-15;
/M: SY='F'; M=-14,-30,-20,-37,-29, 46,-32,-23, 15,-28, 16,  7,-23,-28,-33,-22,-19, -8, 14, -5, 15,-29;
/M: SY='R'; M=-12, -4,-26, -7,  1, -9,-22, -3,-10,  5, -9, -6,  0,-18,  0,  8, -8, -3,-12,-16,  5, -2;
/M: SY='P'; M= -9,-20,-34,-14, -4,-21,-22,-20,-12,-14,-14,-12,-20, 61,-12,-19,-11, -5,-21,-28,-23,-12;
/M: SY='T'; M=  3, -1,-15, -7, -4,-17,-15, -7,-17,  0,-18,-11,  2,-11, -3, -4, 15, 25, -7,-29,-10, -4;
/M: SY='M'; M= -8,-13,-30,-14, -2,-12,-14,-10,-10,  1,-10,  4,-13,-11, -2, -5,-14,-13,-12,  1, -1, -2;
/M: SY='E'; M= -5,  1,-27,  3, 24,-27,-17, -3,-23, 17,-20, -8, -1, -8, 18, 11, -1, -7,-21,-25,-14, 20;
/M: SY='E'; M=-11, 13,-30, 23, 54,-31,-19,  1,-30,  9,-21,-19,  2, -1, 21,  0,  0,-10,-30,-30,-19, 38;
/M: SY='F'; M=-18,-29,-20,-38,-28, 67,-29,-18,  4,-28, 15,  7,-21,-29,-35,-19,-21,-10,  2,  5, 25,-27;
/M: SY='K'; M= -1, -1,-23,  0,  4,-24,-16, -6,-19,  5,-20,-11, -2, -2,  2,  1,  3,  2,-12,-28,-14,  2;
/M: SY='D'; M=-17, 42,-27, 49, 13,-33, -8,  3,-34,  3,-29,-26, 29,-14,  1,  0,  2, -7,-29,-38,-19,  6;
/M: SY='P'; M=-11,-21,-31,-19,-11,  1,-15,-18,-13,-16,-15, -8,-17, 37,-18,-19,-11, -8,-18,-18,-12,-16;
/M: SY='L'; M= -9,-21,-25,-23,-11, -2,-27,-13, 14,-18, 17, 15,-19,-15, -7,-16,-16, -8,  4,-19,  0,-11;
/M: SY='D'; M= -4,  1,-24,  3,  2,-21, -3, -8,-19, -1,-17,-12,  0,-14,  0, -6,  2, -5,-16,-24,-10,  0;
/M: SY='Y'; M=-20,-25,-25,-29,-25, 53,-30,  2,  0,-19,  5,  0,-20,-30,-24,-15,-20,-10, -5, 21, 57,-25;
/M: SY='I'; M=-12,-28,-19,-37,-28,  9,-37,-24, 34,-28, 16, 14,-21,-24,-21,-27,-20,-10, 20,-15,  8,-28;
/M: SY='E'; M= -4,  6,-25, 12, 30,-27,-14, -5,-27, 11,-23,-18,  3, -6, 11,  5,  6, -3,-22,-30,-18, 20;
/I:         I=-14; MI=0; MD=-29; IM=0; DM=-29;
/M: SY='R'; M= -5, -9,-24, -9,  1,-17,-19, -5,-14,  9, -9, -4, -5,-16,  1, 10, -5, -5,-10,-24, -9, -1;
/M: SY='I'; M= -9,-26,-24,-30,-22,  5,-34,-19, 29,-22, 16, 12,-22,-24,-18,-21,-18, -8, 22,-14, 10,-23;
/M: SY='E'; M= -8, 10,-24,  9, 15,-24,-14, -3,-25, 10,-22,-16, 11,-12,  6, 15,  4,  1,-21,-29,-16,  9;
/M: SY='Q'; M= -9,  1,-29,  5,  7,-26,-17, -1,-23, 10,-23,-12, -1, -1, 15,  9, -2, -7,-23,-22, -8, 10;
/M: SY='M'; M=-10,-14,-24,-19,-12, -2,-20,-10,  2, -9,  6,  7,-10,-21, -5, -6,-12, -5, -3,-17,  1,-10;
/M: SY='G'; M= 20,-11,-21,-15,-17,-25, 37,-21,-25,-16,-20,-15, -5,-17,-17,-20,  3,-11,-14,-21,-25,-17;
/M: SY='E'; M= -5, -7,-24, -7,  7,-18,-14, -4,-13,  2,-10, -3, -6,-14,  1,  1, -4, -7,-10,-25,-12,  3;
/I:         I=-14; MI=0; MD=-29; IM=0; DM=-29;
/M: SY='K'; M= -9, -4,-27, -3,  7,-25,-19,-11,-23, 31,-24,-10, -3, -8,  5, 22, -5, -7,-14,-24,-12,  5;
/M: SY='Y'; M= -4,-11,-22,-14,-14, 13,-18,  6, -7,-11, -9, -7, -7,-23, -9,-11, -1, -2, -9,  3, 37,-14;
/M: SY='G'; M=  0,-10,-30,-10,-20,-30, 70,-20,-40,-20,-30,-20,  0,-20,-20,-20,  0,-20,-30,-20,-30,-20;
/M: SY='I'; M=  5,-23, -7,-31,-23, -6,-25,-22, 20,-21, 10, 14,-19,-21,-16,-23,-12, -7, 16,-24, -8,-21;
/M: SY='C'; M=  1,-24, 33,-30,-27, -9,-27,-28,  5,-24,  1, -1,-23,-30,-26,-24,-10, -5, 18,-34,-17,-27;
/M: SY='K'; M=-12, -3,-23, -4,  6,-27,-20, -9,-30, 42,-27,-10, -1,-14,  8, 36,-10,-10,-20,-21,-11,  6;
/M: SY='V'; M= -5,-30,-18,-34,-29,  1,-34,-29, 36,-25, 18, 15,-26,-26,-25,-24,-16, -5, 39,-25, -5,-29;
/M: SY='I'; M= -7,-26,-22,-31,-24, -4,-33,-26, 30,-15,  9, 11,-21,-23,-19,-14,-15, -6, 30,-24, -5,-24;
/M: SY='P'; M= -7,-20,-36,-14, -4,-26,-21,-19,-13, -9,-23,-15,-18, 65, -9,-14,-10, -9,-22,-28,-25,-11;
/M: SY='P'; M=-10,-21,-39,-13, -3,-27,-22,-21,-13,-12,-25,-16,-20, 80,-11,-21,-11,-10,-24,-29,-27,-12;
/M: SY='P'; M=  0, -2,-25,  2,  6,-25,-13,-13,-18, -3,-23,-17, -3, 21, -4,-11,  3, -3,-16,-31,-22, -1;
/M: SY='D'; M= -3, 11,-23, 14,  9,-20,  4, -8,-27, -7,-23,-20,  9,-12, -4,-11,  7, -5,-21,-29,-18,  3;
/M: SY='W'; M=-12,-34,-37,-37,-28, 20,-21,-27,-11,-21,-11,-13,-32,-28,-24,-20,-29,-21,-15, 92, 22,-22;
/M: SY='K'; M=-10,  0,-16,  0,  1,-22,-18, -9,-21, 13,-15, -9,  0,-16,  3, 12, -4, -3,-15,-27,-12,  1;
/M: SY='P'; M=-10,-10,-21, -7,  2,-27,-19,-15,-21,  0,-26,-15, -9, 43, -5,-10, -8, -9,-25,-30,-24, -5;
/M: SY='P'; M=-12,-14,-33, -9,  5,-17,-22,-12,-19,  0,-18,-12,-13, 33, -1, -1,-10,-10,-23,-23,-16,  0;
/I:         E1=0; IE=-105; DE=-105;
» more

Post-processing [info]

PROMOTED_BY PS51184

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2017_11 which contains 556'196 sequence entries.


Total number of hits 54 in 54 different sequences
Number of true positive hits 54 in 54 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 0
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 100.00 %

Comments [info]

Matrix type [info] protein_domain
Scaling database [info] reversed
Author [info] CJA_Sigrist
Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 1
Feature key [info] DOMAIN
Feature description [info] JmjN
Version [info] 5

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
54 sequences

ECM5_YEAST  (Q03214    ), ELF6_ARATH  (Q6BDA0    ), GIS1_YEAST  (Q03833    ), 
JARD2_CHICK (Q5F363    ), JARD2_DANRE (Q1LVC2    ), JARD2_HUMAN (Q92833    ), 
JARD2_MOUSE (Q62315    ), JHD2_YEAST  (P47156    ), JM703_ORYSJ (Q53WJ1    ), 
JM705_ORYSJ (Q5N712    ), JM706_ORYSJ (Q336N8    ), JMJ14_ARATH (Q8GUI6    ), 
JMJ15_ARATH (O64752    ), JMJ16_ARATH (C0SUT9    ), JMJ18_ARATH (F4I6G4    ), 
JMJ19_ARATH (Q8L7T6    ), JMJ2_SCHPO  (Q9US53    ), JMJ3_SCHPO  (O94691    ), 
KD5BB_DANRE (Q6IQX0    ), KDM4A_DROME (Q9V333    ), KDM4A_HUMAN (O75164    ), 
KDM4A_MOUSE (Q8BW72    ), KDM4A_PONAB (Q5RD88    ), KDM4B_DROME (Q9V6L0    ), 
KDM4B_HUMAN (O94953    ), KDM4B_MOUSE (Q91VY5    ), KDM4C_HUMAN (Q9H3R0    ), 
KDM4C_MOUSE (Q8VCD7    ), KDM4D_HUMAN (Q6B0I6    ), KDM4D_MOUSE (Q3U2K5    ), 
KDM4D_RAT   (A1A5Q5    ), KDM4E_HUMAN (B2RXH2    ), KDM4_CAEEL  (Q9U297    ), 
KDM5A_HUMAN (P29375    ), KDM5A_MOUSE (Q3UXZ9    ), KDM5B_CHICK (Q5F3R2    ), 
KDM5B_HUMAN (Q9UGL1    ), KDM5B_MOUSE (Q80Y84    ), KDM5C_CANLF (Q38JA7    ), 
KDM5C_HUMAN (P41229    ), KDM5C_MOUSE (P41230    ), KDM5C_PIG   (A1YVX4    ), 
KDM5D_CANLF (Q30DN6    ), KDM5D_HUMAN (Q9BY66    ), KDM5D_MOUSE (Q62240    ), 
KDM5D_PANTR (Q5XUN4    ), KDM5_CAEBR  (Q61T02    ), KDM5_CAEEL  (Q23541    ), 
KDM5_DROME  (Q9VMJ7    ), LID2_SCHPO  (Q9HDV4    ), MSC1_SCHPO  (Q9UT79    ), 
REF6_ARATH  (Q9STM3    ), RPH1_YEAST  (P39956    ), SE14_ORYSJ  (Q10RP4    )
» more

PDB
[Detailed view]
121 PDB

2GP3; 2GP5; 2OQ6; 2OQ7; 2OS2; 2OT7; 2OX0; 2P5B; 2PXJ; 2Q8C; 2Q8D; 2Q8E; 2VD7; 2W2I; 2WWJ; 2XML; 2YBK; 2YBP; 2YBS; 3DXT; 3DXU; 3NJY; 3OPT; 3OPW; 3PDQ; 3RVH; 3U4S; 4AI9; 4BIS; 4D6Q; 4D6R; 4D6S; 4GD4; 4HON; 4HOO; 4IGO; 4IGP; 4IGQ; 4LXL; 4URA; 4V2V; 4V2W; 4XDO; 4XDP; 5A1F; 5A3N; 5A3P; 5A3T; 5A3W; 5A7N; 5A7O; 5A7P; 5A7Q; 5A7S; 5A7W; 5A80; 5ANQ; 5CEH; 5E6H; 5F2S; 5F2W; 5F32; 5F37; 5F39; 5F3C; 5F3E; 5F3G; 5F3I; 5F5A; 5F5C; 5F5I; 5FJH; 5FJK; 5FP4; 5FP8; 5FP9; 5FPA; 5FPB; 5FPL; 5FPU; 5FPV; 5FUN; 5FUP; 5FV3; 5FWE; 5FWJ; 5FY8; 5FYC; 5FYH; 5FYI; 5FYT; 5FYU; 5FYY; 5FYZ; 5FZ0; 5FZ1; 5FZ3; 5FZ4; 5FZ6; 5FZ7; 5FZ9; 5FZA; 5FZB; 5FZC; 5FZH; 5FZK; 5FZL; 5ISL; 5IVB; 5IVC; 5IVE; 5IVF; 5IVJ; 5IVV; 5IVY; 5IW0; 5IWF; 5K4L; 5KR7; 5LW9; 5LWB
» more

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