Entry: PS51214

Forthcoming changes to the profile format
General information about the entry

Entry name [info] IBB
Accession [info] PS51214
Entry type [info] MATRIX
Date [info] JUN-2006 (CREATED); OCT-2013 (DATA UPDATE); JUN-2014 (INFO UPDATE).
PROSITE Doc. [info] PDOC51214
Associated ProRule [info] PRU00561

Name and characterization of the entry

Description [info] IBB domain profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=64;
/DISJOINT: DEFINITION=PROTECT; N1=6; N2=59;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=2.2827017; R2=0.0051970; TEXT='NScore';
/NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=4918.00812; R2=19.24884; TEXT='HScore';
/CUT_OFF: LEVEL=0; SCORE=1197; N_SCORE=8.5; H_SCORE=24244; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=812; N_SCORE=6.5; H_SCORE=20529; MODE=1; TEXT='?';
/DEFAULT: M0=-18; D=-100; I=-100; B1=-1000; E1=-1000; MI=-255; MD=-255; IM=-255; DM=-255;
...
                A   C   D   E   F   G   H   I   K   L   M   N   P   Q   R   S   T   V   W   Y
/I:         B1=0; BI=-255; BD=-255;
/M: SY='S'; M=-21, 21,-10, -6, -3, 13,-38,-38, 13,  4, -5,-23,-47,-29,-28, 61,  4,-38,-56,-44;
/M: SY='F'; M=-14,-49,-23,-50, 78, 21,-41,-28,-15,  2,  1,-34,-20,-48,-48, 15, -7,-31,-32, -8;
/M: SY='S'; M= 21,-36,-26,  5,-50,-32,-22,-33,-30,-21,-35, -4,-42,-27,-37, 74,-11,  7,-60,-42;
/M: SY='V'; M=  6,-36,-53,-54,-35, 17,-55,  7,-49, 21, 40,-46,-57,-47,-52, 10,-27, 55,-57,-47;
/M: SY='S'; M=-26,-43, 10,-20, 22,-43,-37,-27,-34, 21, 43, 11,-42,-33,-11, 58,-10,-31,-50,-35;
/M: SY='M'; M= -4,-47, 15, -2,-42,-33, 24,-28,  9,-25, 75,-26,-50, 39, -2, 26,-27, -7,-53,-18;
/M: SY='M'; M=  4,-46, 35, 33,-51,-15,-34,-34,-28,-36, 49,  8,-47, -4,-23, 39,  9, -6,-60,-51;
/M: SY='M'; M= 13,-43, 20,-14,-16,-50, 21, -6,-41, 28, 75, -9, 13,-36,-45,-22, -9,-22,-52,-24;
/M: SY='N'; M=  5,-12, 16, 12,-31,-42,-31,-27,-13,-23, 39, 49, 25,-25, 19, 12,  3,-38,-61,-49;
/M: SY='S'; M=-14,-46, -2,  8,-24, -3, -1,-38,-30,-26,-13, 35, 31,-12,-23, 52, 18,-32,-61,-47;
/M: SY='P'; M=  6,-48,-20, -5,-60,  0,-35,-33, 16,-48, -8,  3, 43,  0, 32, 26, 24,-32,-63,-53;
/M: SY='N'; M= 24,-46, -6, -2, 10,  8,-34,-28, 12,-12,-25, 25,  1,-17, -5, 19,  1,-37,-52, -8;
/M: SY='K'; M= 26,-46, 16, -2,-46, -5,-37, -1, 26,  0, 17,  1,-49,-12, 16, -8,-14, -7,-58,-32;
/M: SY='P'; M= -6,-51, 18, 15,-56,-46, 13,-32,-17,-30, 29,  5, 70, -1,-15,  7, 18,-37,-66,-50;
/M: SY='H'; M= -2,-56, 24, 42,-53, -6, 68,-26, -8,-40, 15, 37,-29,-12,-21,  0,-28,-32,-59,-38;
/M: SY='P'; M= -9,-52, -5, 16, -1, -9, 37,-18,-20,-24,-38,  1, 50, -7,  3, -4, -1, -5,-49, 19;
/M: SY='R'; M=-46,-68,-42,-27,-61,-57,  7,-58, 20,-47, 10,-26,-56,-10,101,-36,-39,-54,-57,-48;
/M: SY='L'; M=-21,-46,-49,-37,-30,-48,-38, 10, 13, 43, 40,-41,-57, 24, 36, -4,-34,-20,-49, -5;
/M: SY='K'; M=  6,-28,-14, 11,-60,-19,  1,-40, 41,-45,-28, 29,-44, 26,  4, 35, 17,-43,-61,-49;
/M: SY='Q'; M= -2,-43,  6,-11,-51,-17,-25,-15,  1,-33,  9, 40,-49, 56, 33, 19,-12,-40,-56,-13;
/M: SY='Y'; M=-52,-61,-61,-54, 73,-49, 29,-34,-47,-29,-31,-48,-69,-46,  3,-52,-50,-39, -1,100;
/M: SY='K'; M=-36,-64,-11,-15,-67,-46,-30,-55, 92,-53,-11,-12,-42, -7, 22,-14,-33,-53,-62,-51;
/I:         I=-14; MD=-37;
/M: SY='N'; M= -4, 10,-12,-35,-27, -7,-26,-59,  5,-62,-52, 81,-53,-31,-23, 22, -5,-54,-63,-20; D=-14;
/I:         I=-14; MI=0; MD=-37; IM=0; DM=-37;
/M: SY='K'; M=-27,-61,-15,-16, -3,  6,-35,-35, 60,-29,-41, 23,-54,-24, -5,-29,-28, -5,-54,  4; D=-14;
/I:         I=-14; DM=-37;
/M: SY='G'; M= 12,-48, 11,-34,-38, 43,-31,-42, 19,-34,-42, -6,-49,-11, -5, 13,  7,-14,-45, 34;
/M: SY='K'; M=-21,-50,-41,-33, 26,-51,-36, -5, 52,  2, -6, -9,-52,-25, 26, 13,-14,  9,-47, -7;
/M: SY='D'; M= -6,-55, 75,  1,-26,-40,-32,-30,  8,-35,-46, 39,-48, -6,-24, 17, -2,-33,-65,-53;
/M: SY='A'; M= 36,  9,-42,-20,  7, -3, -4,-28,-37,  9, -4,-37, 27, 10,-43, 14, 14,-11,-55,-39;
/M: SY='E'; M=-13,-61, 61, 63,-64,-46,-27,-55, -8,-47,-47, 15,-46, 28,-29,-13, 12,-42,-64,-55;
/M: SY='E'; M=-22,-63, 35, 74,-63,-39,-25,-31,  5,-39,-43, -5,-46, 45,-24,-18,  2,-47,-61,-53;
/M: SY='M'; M=-11,-43,-44,-22,-36, 18,-43,-19,-20, 31, 71,-38, 20, -6,-21, 17,-11,-25,-55,-47;
/M: SY='R'; M=-13,-66,-34, 19,-64,-54,-25,-63, 12,-53,-43,-26,-53, -9, 98,-33,-38,-54,-58,-51;
/M: SY='R'; M=-45,-69,-21,  5,-63,-56,-25,-61, 19,-50, -7,-25,-54, 16, 97,-34,-39,-55,-58,-51;
/M: SY='R'; M=-43,-68,-38,-22,-63,-54, 16,-60, 47,-51,-11,-25,-52, 18, 91,-34,-38,-55,-58,-47;
/M: SY='R'; M=-46,-69,-43,-27,-63,-58,-25,-61, 12,-49, -7,-26,-56,-10,104,-36,-39,-55,-57,-51;
/I:         I=-26; MD=-65;
/M: SY='E'; M=-41,-63,  6, 68,-56,-55, 36,  8, -6,-46,-41, 24,-51, -7,  5,-31, -2,-13,-61,-46; D=-26;
/I:         I=-26; MD=-65;
/M: SY='E'; M=-22,-69, 49, 74,-19,-53,-31,-61,-25,-62,-54,  0,-51,-13,-36,-29,  3,-50,-64,-54; D=-26;
/I:         I=-26; MD=-65;
/M: SY='Q'; M=-21, -3,  0, 24,-35,-48, 13, -3,-35, -4,-30, 21,-59, 39,-40,-24,-30, 31,-63,-48; D=-26;
/I:         I=-26; MI=-65; IM=-65; DM=-65;
/M: SY='Q'; M=-24,  5,-31,  5,-26,  9,-35,-27,-29,  6, 25, 15,-51, 51,-33, 13, 34, -3,-56,-46;
/M: SY='V'; M=-18,-34,-66,-62,-28,-68,-65, 37,-57, 35, -7,-62,-64,-56,-59,-32,-29, 71,-57,-43;
/M: SY='E'; M=-36, -2,  2, 81,-66,-35,-21,-40,-13,-56,-43,-23,-46, 65,-22,-13,-24,-42,-60,-51;
/M: SY='L'; M=-45,-40,-67,-64, -9,-75,-59, 60,-24, 61,  1,-64,-68,-54,-21,-59,-38,  2,-52,-40;
/M: SY='R'; M=-45,-70,-40,-22,-65,-56,-23,-64,  6,-52,-41,-25,-55, 42,100,-34,-39,-57,-58,-50;
/M: SY='K'; M=-35,-65,-29, -2,-69,-46,-29,-58, 92,-56,-43,-22,-42,  7, 22,-10,-33,-55,-62,-51;
/M: SY='Q'; M= 33, -9, -3,  2,-61,-34,-24,-50, -8,-45,-40, 58,-46, 64,-25,  9, -1,-37,-62,-50;
/M: SY='K'; M=-26,-63,-16,-16,-65,-21, 25,-35, 80,-53,-42,-16,-44, 23, 33,-11,-34,-51,-61,-46;
/M: SY='R'; M=-43,-67,-40,-25,-64,-32,-27,-55, 46,-51,-42,-26,-53,-10, 94,-34,-38,-28,-59,-51;
/M: SY='E'; M=-28,-62, 62, 68,-16,-52,-30,-40,-26, 10,-36,  8,-50,-15,-36,-31,-38,-33,-60,-49;
/M: SY='E'; M=-40,  0, 62, 76,-68,-50,-24,-64, -7,-63,-51, -4,-47, 35,-14,-27,-37,-58,-64,-56;
/M: SY='Q'; M= -4,-51,-29,-22,-35,-24, 34,-21,-14, -7,-16, 40,-51, 65,-14, 10,  0,-25,-44, 32;
/M: SY='L'; M=-45,-40,-70,-66, 37,-73,-56, 30,-59, 60, 53,-65,-70,-56,-57,-58,-39, 17,-43,-26;
/M: SY='M'; M=  1,-46,-36, -1, 37,-50,-35,-14,-24, 36, 39, 35,-58, 12,-17, -3,-33,-25,-45,-28;
/M: SY='K'; M=-35,-64,-29, -7,-64,-46, 47,-58, 87,-56,-43,-21,-43, -7, 16,  1,-33,-56,-60,-42;
/I:         I=-26; MI=0; MD=-65; IM=0; DM=-65;
/M: SY='R'; M=-45,-68,-37,-25,-59,-53,-26,-58, 46,-32,-41, 12,-53,-11, 90,-34,-38,-55, 30,-47;
/M: SY='R'; M=-47,-70,-42,-27,-64,-58,-25,-65,  8,-53,-43,-26,-56, -9,106,-36,-40,-57,-58,-51;
/M: SY='N'; M=-16,-57,-14,-26,-42,-11,-21,-47,-14, -3,-39, 91, -8,  4, 21,-12,-19,-48,-63,-51;
/M: SY='I'; M=  5,-39,-41,  6, -6,-28,-51, 51,-46, 11, 23,-52,-28, -7,-51,-42,-26, 43,-54,-29;
/M: SY='N'; M=  9,-16, 12, 16,-14, 11,-36,-24,-26,-36,-40, 31, 27,-11,-40, 13, 24,  1,-60,-39;
/M: SY='M'; M=  0,-33, 23,-16, -3, -1,-14,-15,-18, 21, 25, -9,-32, 24,-28,  2, 14,  2,-54,-35;
/M: SY='D'; M= -3,-51, 48, 21,  8,-15,-36,-27,-31,-12, -3,-10, 31, 25,-29,  6, -8,-10,-58,-42;
/M: SY='W'; M= 14,-52, 35, 25,-51, -4, -7,-21,-29,-37,-44, 23, 32,-15, -7,  1,-11,-32, 68,-37;
/M: SY='D'; M=  0,-48, 36, 25,-41,-11,-33, -6,-29,-11,-35, 24,-12, 25,-36, 34, -3,-14,-62,-51;
/M: SY='D'; M= -3, 29, 42, 13,-55, 26,-17,-43,-33, -4,-27,  7, 18, 15,-28,-11, 16,-42,-63,-55;
/M: SY='D'; M= 10,-47, 38, 29,  7,-11,-36, -8,-33,-26, 12,-19,  3, -6,-41, 26,  9,-16,-55,-26;
/I:         E1=0; IE=-255; DE=-255;
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Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2014_07 which contains 546'000 sequence entries.


Total number of hits 46 in 46 different sequences
Number of true positive hits 44 in 44 different sequences
Number of 'unknown' hits
Number of false positive hits 2 in 2 different sequences
Number of false negative sequences 0
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 95.65 %
Recall (true positives / (true positives + false negatives)) 100.00 %

Comments [info]

Matrix type [info] protein_domain
Scaling database [info] reversed
Author [info] CJA_Sigrist
Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 1
Feature key [info] DOMAIN
Feature description [info] IBB
Version [info] 2

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
44 sequences

IMA1A_DICDI (Q557F4), IMA1A_ORYSJ (Q71VM4), IMA1B_ORYSJ (Q9SLX0), 
IMA1_ARATH  (Q96321), IMA1_CAEEL  (Q22560), IMA1_HUMAN  (P52292), 
IMA1_MOUSE  (P52293), IMA1_SCHPO  (O14063), IMA1_XENLA  (P52171), 
IMA1_YEAST  (Q02821), IMA2_ARATH  (O04294), IMA2_CAEEL  (P91276), 
IMA2_SCHPO  (O94374), IMA3_CAEEL  (Q19969), IMA3_HUMAN  (O00629), 
IMA3_MOUSE  (O35343), IMA4_HUMAN  (O00505), IMA4_MOUSE  (O35344), 
IMA5_BOVIN  (A2VE08), IMA5_CHICK  (Q5ZML1), IMA5_HUMAN  (P52294), 
IMA5_MOUSE  (Q60960), IMA5_PONAB  (Q5R909), IMA5_RAT    (P83953), 
IMA5_XENLA  (P52170), IMA6_DANRE  (Q503E9), IMA6_HUMAN  (O15131), 
IMA6_RAT    (Q56R16), IMA7_BOVIN  (Q0V7M0), IMA7_HUMAN  (O60684), 
IMA7_MOUSE  (O35345), IMA7_PONAB  (Q5RBV0), IMA8_BOVIN  (C1JZ66), 
IMA8_HUMAN  (A9QM74), IMA8_MOUSE  (C0LLJ0), IMA8_PIG    (C6K7I2), 
IMAB_DICDI  (Q76P29), IMA_DROME   (P52295), IMA_SOLLC   (O22478), 
SPN1_BOVIN  (Q2TBK8), SPN1_CHICK  (Q5ZI43), SPN1_HUMAN  (O95149), 
SPN1_MOUSE  (Q80W37), SPN1_RAT    (Q68FP5)
» More

UniProtKB/Swiss-Prot
False positive sequences
2 sequences

TMCO6_HUMAN (Q96DC7), TMCO6_MOUSE (Q8BQX5)

		
PDB
[Detailed view]
11 PDB

1QGK; 1QGR; 1WA5; 2P8Q; 2Q5D; 3GB8; 3GJX; 3LWW; 3NBY; 3NBZ; 3NC0

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