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PROSITE entry PS51286

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General information about the entry

Entry name [info]	RAP
Accession [info]	PS51286
Entry type [info]	MATRIX
Date [info]	01-JUL-2007 CREATED; 10-MAY-2017 DATA UPDATE; 29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info]	PDOC51286
Associated ProRule [info]	PRU00619

Name and characterization of the entry

Description [info]

RAP domain profile.

Matrix / Profile [info]

/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=61;
/DISJOINT: DEFINITION=PROTECT; N1=6; N2=56;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=2.8657391; R2=0.0238114; TEXT='NScore';
/NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=3190.8044434; R2=1.1494565; PRIORITY=1; TEXT='Heuristic 5.0%';
/CUT_OFF: LEVEL=0; SCORE=279; H_SCORE=3512; N_SCORE=9.5; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=153; H_SCORE=3367; N_SCORE=6.5; MODE=1; TEXT='?';
/DEFAULT: B1=*; E1=*; MM=*; II=*;

...

                A   C   D   E   F   G   H   I   K   L   M   N   P   Q   R   S   T   V   W   Y
/I:         B1=-85; E0=*; BD=-61;
/M: SY='I';  M=-36,-34,-59,-53, -1,-51,-40, 22,-49, 13, -4,  0,-52,-13,-47,-19, -4, 20,-39,  4; M0=-21;
/I:         MM=0; MI=-112; MD=-123; IM=-9; II=-11; DM=-7; DD=-14;
/M: SY='C';  M= 23, 27,-12,-66,-46,-20,-56, 17,-63,-10,-36,-61,-64,-60,-61,-56,-46, 19,-54,-50; M0=-31;
/I:         MM=0; MI=-112; MD=-123; IM=-9; II=-11; DM=-7; DD=-14;
/M: SY='I';  M=-41,-39,-18,-59, 13,-58,-46, 31,-55,  7,-30,-54,-58,-51,-53,-21,-41, 13, 19,-41; M0=-29;
/I:         MM=0; MI=-113; MD=-123; IM=-9; II=-11; DM=-7; DD=-14;
/M: SY='E';  M=-33, 10, -8, 30,  3,-21,-30,-44,-14,  4, 10, -5,-45, -3,-32,-11,-13, -6,-48,-42; M0=-14;
/I:         MM=0; MI=-113; MD=-123; IM=-9; II=-11; DM=-7; DD=-14;
/M: SY='C';  M=-10, 33,-59,-53,  7,-35,-40, 21,-49, -7,-26,-48,-52,-45,-19,-42,-17, 23,-39,  7; M0=-23;
/I:         MM=0; MI=-113; MD=-123; IM=-9; II=-11; DM=-7; DD=-14;
/M: SY='N';  M= -6, -4, 25,-17,-12,-21,  2,-18,-36,  3, -6, 27,-49,-23,-20,-38,-14,-12,  9,-37; M0=-14;
/I:         MM=0; MI=-113; MD=-123; IM=-9; II=-11; DM=-7; DD=-14;
/M: SY='G';  M=-12,-48, 10, -7,-51, 30, -4,-49, -9,-26,-39,  0,  0,-25,-19, -4,-33,-44,-50, -2; M0=-16;
/I:         MM=0; MI=-113; MD=-123; IM=-9; II=-11; DM=-7; DD=-14;
/M: SY='P';  M=-34, -3,-17,  0,  6,-21,  3,-10,  6,-15,-33,-33, 30,-29,  3,-15,-33,-26, 13, 17; M0=-12;
/I:         MM=0; MI=-113; MD=-123; IM=-9; II=-11; DM=-7; DD=-14;
/M: SY='H';  M=-33,-48, -2, -8, -1,-12, 24,-49,  6,-25,  8,  8,-10,  5,-10, 13,  8,-17,  2, 13; M0=-9;
/I:         MM=0; MI=-113; MD=-123; IM=-9; II=-11; DM=-7; DD=-14;
/M: SY='H';  M= -1, 10, -5,-26,-16,-43, 44,-21, -2,-48,-39,  0, -8,  2, -5, -1,-18,-29,-50, -1; M0=-15;
/I:         MM=0; MI=-113; MD=-123; IM=-9; II=-11; DM=-7; DD=-14;
/M: SY='Y';  M=-41,-39,-64,-21, 34,-57,  3, -3,-54,-11,  2,-52,-57,-50,-52,-47,-41, -1,-39, 34; M0=-30;
/I:         MM=0; MI=-113; MD=-123; IM=-9; II=-11; DM=-7; DD=-14;
/M: SY='C';  M= -4, 34,-23,-53,  8,-21,-40,  9,-20, -9, -3, 10,-17,-45,-47,  0,-35,  3,-39, 27; M0=-14;
/I:         MM=0; MI=-113; MD=-123; IM=-9; II=-11; DM=-7; DD=-14;
/M: SY='R';  M=-14,-48, -9, -6, -6,-43, 12,  3,  0, -1,-39, -7,-16, 11, 19,  8,  4, -8,-50,  5; M0=-6;
/I:         MM=0; MI=-113; MD=-123; IM=-9; II=-11; DM=-7; DD=-14;
/M: SY='N';  M=-33,-48, 17, -4,-15,  5,-29,-10,  1,-11,-39, 29,-44, -9, -4,-12,  3,-20,-50,-43; M0=-12;
/I:         MM=0; MI=-113; MD=-123; IM=-9; II=-11; DM=-7; DD=-14;
/M: SY='S';  M= -9,-47, -6,-15,-20, -8,-30,  9,  4,  4,-38, -1, -9,-10, -7, 18, 12,-11,  1,-43; M0=-6;
/I:         MM=0; MI=-113; MD=-123; IM=-9; II=-11; DM=-7; DD=-14;
/M: SY='N';  M=-21,-15, 15,  5,  3, -4,  2, -5,  6,-11,-39, 16,  4,  0,  4, -2, -7,-44,-50, -4; M0=-6;
/I:         MM=0; MI=-113; MD=-123; IM=-9; II=-11; DM=-7; DD=-14;
/M: SY='H';  M=-24,-48,  7,  6, -8, -3, 19,-49,  6,-19,  3,  6, -1,  5,  7,  5, -3,  0,  1, -1; M0=-5;
/I:         MM=0; MI=-113; MD=-123; IM=-9; II=-11; DM=-7; DD=-14;
/M: SY='L';  M=-12,-46,-33, -4, -8, -4,-10, -1,  9, 10,  5,  3,  1, -3,  7, -3, -3, -7,-48, 10; M0=-4;
/I:         MM=0; MI=-113; MD=-123; IM=-9; II=-11; DM=-7; DD=-14;
/M: SY='T';  M=-19,-41,-38,-32, -7,-24,  4,  3,  6, 10, -9,  3,-19,  1,  7,  7, 16, -5,-44,-39; M0=-8;
/I:         MM=-11; MI=-113; MD=-9; IM=-9; II=-11; DM=-7; DD=-14;
/M: SY='C';  M=-25, 17,-34, -8, -3,-38,  2,  2,  0,  7,  3,  2, -7,-25, 11,  9, -1,-22, 13, 14; M0=-7;
/I:         MM=-30; MI=-6; MD=-22; IM=-24; II=-3; DM=-54;
/M: SY='N';  M= -8, 10,  5,-21, -1,-33,  9, 10, -3,  2,-19, 20,-34,-18,-23,  1, 16,-22,-31,-26; M0=-8;
/I:         MM=0; MI=-98; MD=-109; IM=-9; II=-11; DM=-2; DD=-31;
/M: SY='G';  M= -4,-43,-34, -9,-14, 29,-30,-18,-13,-15,-34,-15,  0, -5,-32,  3,  3,-19,-46,-10; M0=-11;
/I:         MM=0; MI=-112; MD=-122; IM=-9; II=-11; DM=-8; DD=-13;
/M: SY='N';  M=-11,-47,-31, -5, -7,-20,  9, -4, 14, -2,-38, 16, -7,  9,  1,  9, -9, -4,  2, -6; M0=-5;
/I:         MM=0; MI=-112; MD=-123; IM=-9; II=-11; DM=-3; DD=-26;
/M: SY='T';  M=-20, -2,-56, -3,  8,-22, 14, -8,-20, -7,  0,-46,-51, -5,-17,  3, 26,  6,  1,  7; M0=-11;
/I:         MM=0; MI=-113; MD=-123; IM=-9; II=-11; DM=-7; DD=-14;
/M: SY='N';  M= 11,-46,-10,-27,-48,-43, -5,  7, 10, -1, 11, 14,-44, 11, -3,  2, -8, -4,-48,-11; M0=-9;
/I:         MM=0; MI=-113; MD=-123; IM=-9; II=-11; DM=-7; DD=-14;
/M: SY='M';  M=-19, -2,-59,-53, 12,-51,-40,  6,-19, 20, 32,-48,-52,-14,-19,-21,-20,-10,  0,  8; M0=-19;
/I:         MM=0; MI=-113; MD=-123; IM=-9; II=-11; DM=-7; DD=-14;
/M: SY='K';  M=-13,-52,-39,-32,-56,-48, -5,-19, 32,-27,-43,-17,-49, 13, 19,-38, -7,-49,-53, -3; M0=-23;
/I:         MM=0; MI=-113; MD=-123; IM=-9; II=-11; DM=-7; DD=-14;
/M: SY='H';  M=-33, -7, -9, -3,-18,-43, 24,  6,  9, -1,  8, 10,-44, 14,  9, -9, -2,-44,-49,  9; M0=-10;
/I:         MM=0; MI=-113; MD=-123; IM=-9; II=-11; DM=-7; DD=-14;
/M: SY='R';  M=-33,-48, -9, -6,-51,-43, -7,-49, 13,-48, -6, 12,-44,  2, 32,-18, -8,-44, 11, -3; M0=-20;
/I:         MM=0; MI=-113; MD=-123; IM=-9; II=-11; DM=-7; DD=-14;
/M: SY='H';  M=-22, 12,-59,-53,  0,-51, 33, 13,-49, 15,  3, -6,-52,  6,-47,-42, -8, -9,-39, 15; M0=-21;
/I:         MM=0; MI=-113; MD=-123; IM=-9; II=-11; DM=-7; DD=-14;
/M: SY='L';  M=-70,-63,-93,-87,  2,-92,-78,  7,-86, 31,  2,-90,-80,-72,-80,-87,-68,-21,-61,-64; M0=-56;
/I:         MM=0; MI=-113; MD=-123; IM=-9; II=-11; DM=-7; DD=-14;
/M: SY='K';  M= -8,-48,-17, 16,-51,-12, -4,-20, 17,-10,-39, 10,-44, 11,  3,  6,  3,-22,-50,-15; M0=-9;
/I:         MM=0; MI=-113; MD=-123; IM=-9; II=-11; DM=-7; DD=-14;
/M: SY='K';  M= 14,-48, -5,-14, -6,-20, -5,  1, 15, -6, -5, -6,-44, 14, -5,  8, -5, -9,-50,-43; M0=-7;
/I:         MM=-1; MI=-44; MD=-123; IM=-1; II=-47; DM=-7; DD=-14;
/M: SY='M';  M= -2,-43,-16, -9, -1,-45, -4, -9,  9, 17, 22,  1,-46,-11,-10,  0,-33,-26,  9,  9; M0=-10;
/I:         MM=0; MI=-113; MD=-123; IM=-9; II=-11; DM=-7; DD=-14;
/M: SY='G';  M=-58,-79, -8,-18,-80, 35,-49,-80, -3,-78,-73,  7,-17,-46,-64,-54,-59,-74,-80,-12; M0=-42;
/I:         MM=0; MI=-113; MD=-123; IM=-9; II=-11; DM=-7; DD=-14;
/M: SY='W';  M=-61,-56,-77,-75, 22,-72, -3,-20,-71,-26,-49,-63,-72,-15,-67,-64,-20,-21, 41, 40; M0=-43;
/I:         MM=0; MI=-62; MD=-123; IM=-2; II=-32; DM=-7; DD=-14;
/M: SY='K';  M=-12,-48, -7,-15,-51,-43, 12,-13, 26,-13,-39, 20,-44,  8,  6, -8, -5,-12,-50,-43; M0=-13;
/I:         MM=0; MI=-113; MD=-123; IM=-9; II=-11; DM=-7; DD=-14;
/M: SY='V';  M=-19,-34,-60,-53,  1,-52, -7, 18,-49,  1,-26,-48, -7,-45,-47,-43,  0, 29,-39,  4; M0=-23;
/I:         MM=0; MI=-52; MD=-123; IM=-1; II=-40; DM=-7; DD=-14;
/M: SY='I';  M= -8, -4,-59,-20, -6,-21, -1, 27,-49, -1,-11,-48,-52,-45, -1, -8,-35, 21,-39,-15; M0=-17;
/I:         MM=0; MI=-113; MD=-123; IM=-9; II=-11; DM=-7; DD=-14;
/M: SY='H';  M= -9,-48,  2,  4,-18,-21, 15, -1, -3,-14,-10, 12,  7, 10, -2,  4, -1,  5,-50,-11; M0=-4;
/I:         MM=0; MI=-113; MD=-123; IM=-9; II=-11; DM=-7; DD=-14;
/M: SY='I';  M=-58,-53,-85,-81, -5,-84,-81, 33,-81,  6,-39,-80,-79,-77,-81,-78,-58, 20,-70,-68; M0=-51;
/I:         MM=0; MI=-113; MD=-123; IM=-9; II=-11; DM=-7; DD=-14;
/M: SY='P';  M=-26, -3,  1,-26,-51,-43, 16,-49, -7,-48,-39, 15, 32,-12,  2,  3,-16,-24,-50,  0; M0=-18;
/I:         MM=0; MI=-113; MD=-123; IM=-9; II=-11; DM=-7; DD=-14;
/M: SY='Y';  M=-18,-48,-15, -3, 20,-43,  8,-10, -7,-31,-39, -2,-17,  0,-14,-12, -8,-44, 29, 35; M0=-14;
/I:         MM=0; MI=-113; MD=-123; IM=-9; II=-11; DM=-7; DD=-14;
/M: SY='W';  M=-20, -3,-16, -4, 21,-19, 23, -7,-28,-20,-36, -7,-45,  7, -2,-12,-16,-40, 30, 29; M0=-13;
/I:         MM=0; MI=-113; MD=-123; IM=-9; II=-11; DM=-7; DD=-14;
/M: SY='E';  M=-33,-48, 17, 29,-51,-43,  3, -7,  0,-48, -7,-13,-44, 10,-30,-12,-10,-14, -1,-11; M0=-17;
/I:         MM=0; MI=-113; MD=-69; IM=-9; II=-11; DM=-7; DD=-14;
/M: SY='W';  M=-54,-51,-73,-69, 10,-67,-43,  0,-65, -5,-10,-17,-67,-59,-62,-22,-53,-46, 58,  1; M0=-40;
/I:         MM=0; MI=-112; MD=-123; IM=-9; II=-11; DM=-5; DD=-19;
/M: SY='N';  M=-13,-48,  6,  3,-30,-11, -5, -4,  9, -6,-24, 21, -8,-12, 14, -4,-16, -7,-50,  7; M0=-5;
/I:         MM=0; MI=-113; MD=-123; IM=-9; II=-11; DM=-7; DD=-14;
/M: SY='Q';  M=-19,-48,  0,  1, -9,-20,  3, -6, 15,-14,  7, 12,  3, 18,  6, -2, -5,-23, -1,-19; M0=-5;
/I:         MM=0; MI=-112; MD=-123; IM=-9; II=-11; DM=-7; DD=-14;
/M: SY='L';  M=-19, 13,-18,-12,-16,-21,-12,-15, -9, 23, 21,-42,-50,  1, -9, -9,-17,-11, 12,  7; M0=-11;
/I:         MM=0; MI=-112; MD=-123; IM=-9; II=-11; DM=-7; DD=-14;
/M: SY='N';  M= -8,  6,  5,  5,  0,-13, -6,-19, 13,-12,-10, 17,-17,-25, 11, -3,  4,-44, -2,  4; M0=-6;
/I:         MM=0; MI=-112; MD=-123; IM=-9; II=-11; DM=-7; DD=-14;
/M: SY='S';  M=-19, -4,  2, -2,-13,  3, -4, -4,  5, -9,  9, 10,-10,  2,-30, 12, 11, -4,-49,-13; M0=-4;
/I:         MM=0; MI=-112; MD=-123; IM=-9; II=-11; DM=-7; DD=-14;
/M: SY='E';  M=  4,-48, 12, 17,-16,-22, -5,-11,  9, -6, -1, -7,-44, -5,  5,  6,-32, -8,-49, -2; M0=-7;
/I:         MM=-3; MI=-112; MD=-23; IM=-9; II=-11; DM=-7; DD=-14;
/M: SY='E';  M=-10,-45, -4, 18, -2,-12, -7,-10,  7, -2,-36, -2, -5,  6, -3, -7, 15,-41, 12,-40; M0=-6;
/I:         MM=-5; MI=-18; MD=-119; IM=-17; II=-5; DM=-3; DD=-26;
/M: SY='Q';  M=  2,-47, 14, 20,-50,-42,-29,-48, 14,-47,-38,  1,-43, 20, -2, -7, -4,-43,-49,-42; M0=-18;
/I:         MM=0; MI=-112; MD=-122; IM=-9; II=-11; DM=-9; DD=-11;
/M: SY='K';  M= -9,-47,-16, -2,-50,-42,  2,-18, 28, -5, -6,-29,-43, 13, 16,-31, -4,-20, -2,-11; M0=-14;
/I:         MM=0; MI=-112; MD=-122; IM=-9; II=-11; DM=-14; DD=-7;
/M: SY='V';  M= -1,-40, -7, 11,  0,-20,-32,  9,  7,  4, 11,-34,-46,  3,-15,-10,-14, 14,-44,-10; M0=-7;
/I:         MM=0; MI=-112; MD=-122; IM=-9; II=-11; DM=-14; DD=-7;
/M: SY='E';  M=  7,-47, 10, 17,-50,-42,  4,-18, 13,-17, -6, 10,-16, 10, -7, -3,-11,-20,-49,-11; M0=-9;
/I:         MM=0; MI=-112; MD=-122; IM=-9; II=-11; DM=-4; DD=-21;
/M: SY='Y';  M=-35,-34,-18,-21, 21,-51,-40, -2,-24, -5,-26,-47,-51,-44,-46, -8,-16,-15,-38, 41; M0=-22;
/I:         MM=0; MI=-112; MD=-123; IM=-9; II=-11; DM=-7; DD=-14;
/M: SY='L';  M= -8,-39,-65,-59,-13,-58,-46, 23,-55, 25,  1,-54,-58,-51,-53,-49,-17, -1,-44,-10; M0=-29;
/I:         MM=0; MI=-112; MD=-123; IM=-9; II=-11; DM=-7; DD=-14;
/M: SY='K';  M= -8, 11,-34, -2, -4,-44, -2,  1, 20,-12,  3, -5,-45,  9, 18, -5,-18, -6,-46,  4; M0=-9;
/I:         MM=0; MI=-112; MD=-122; IM=-9; II=-11; DM=-7; DD=-14;
/M: SY='K';  M=-12, -1,  6, 13,-50,-29,-29, -9, 22,-47,  6, 11,-43,  3,  9,  4,-18,-43,-49,-42; M0=-15;
/I:         B0=*; E1=-10;

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Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2024_05 which contains 572'214 sequence entries.

Total number of hits	28 in 28 different sequences
Number of true positive hits	28 in 28 different sequences
Number of 'unknown' hits	0
Number of false positive hits	0
Number of false negative sequences	0
Number of 'partial' sequences	0

Precision (true positives / (true positives + false positives))	100.00 %
Recall (true positives / (true positives + false negatives))	100.00 %

Comments [info]

Taxonomic range [info]	Eukaryotes
Maximum number of repetitions [info]	1
Matrix type [info]	protein_domain
Scaling database [info]	reversed
Author [info]	CJA_Sigrist
Feature key [info]	DOMAIN
Feature description [info]	RAP
Version [info]	5

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences

28 sequences

FAKD1_HUMAN (Q53R41), FAKD1_MOUSE (Q6DI86), FAKD1_XENLA (Q6GQ66),

FAKD1_XENTR (Q28DE0), FAKD2_HUMAN (Q9NYY8), FAKD2_MOUSE (Q922E6), 
FAKD2_PONAB (Q5R776), FAKD2_RAT   (Q5M7V7), FAKD3_BOVIN (Q58CX2), 
FAKD3_HUMAN (Q14CZ7), FAKD3_MOUSE (Q8BSN9), FAKD3_RAT   (Q68FN9), 
FAKD4_BOVIN (Q3SZK4), FAKD4_HUMAN (Q969Z0), FAKD4_MOUSE (Q91YM4), 
FAKD4_PIG   (Q7YS91), FAKD4_RAT   (Q5M9G9), FAKD4_XENLA (Q6PA48), 
FAKD4_XENTR (Q6DJ55), FAKD5_HUMAN (Q7L8L6), FAKD5_MACFA (Q95KD0), 
FAKD5_MOUSE (Q7TMV3), FAKD5_PONAB (Q5RFI6), FASTK_HUMAN (Q14296), 
FASTK_MOUSE (Q9JIX9), RAA3_CHLRE  (Q9FEC4), RAP_ARATH   (Q8VZE7), 
RAP_ORYSJ   (Q84MH1)

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Retrieve an alignment of UniProtKB/Swiss-Prot true positive hits:
[Clustal format, color, condensed view] [Clustal format, color]
[Clustal format, plain text] [Fasta format]
Retrieve the sequence logo from the alignment