PROSITE entry PS51302

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General information about the entry

Entry name [info]	SIM_C
Accession [info]	PS51302
Entry type [info]	MATRIX
Date [info]	01-MAR-2007 CREATED; 01-OCT-2013 DATA UPDATE; 27-MAR-2024 INFO UPDATE.
PROSITE Doc. [info]	PDOC51302
Associated ProRule [info]	PRU00632

Name and characterization of the entry

Description [info]

Single-minded C-terminal domain profile.

Matrix / Profile [info]

/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=415;
/DISJOINT: DEFINITION=PROTECT; N1=6; N2=410;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=3.6866705; R2=0.0059916; TEXT='NScore';
/CUT_OFF: LEVEL=0; SCORE=804; N_SCORE=8.5; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=470; N_SCORE=6.5; MODE=1; TEXT='?';
/DEFAULT: M0=-50; D=-150; I=-150; B1=-1500; E1=-1500; MI=-305; MD=-305; IM=-305; DM=-305;

...

                A    C    D    E    F    G    H    I    K    L    M    N    P    Q    R    S    T    V    W    Y
/I:         B1=0; BI=-305; BD=-305;
/M: SY='E';  M= -60, -81, -31, 112, -84, -76, -53, -85, -41, -77, -73, -57, -55, -34, -51, -57, -61, -77, -80, -74;
/M: SY='Y';  M= -71, -82, -70, -74, -19, -78, -37, -56, -65, -53, -50, -72, -83, -61, -62, -66, -65, -62, -27, 135;
/M: SY='K';  M= -63, -77, -55, -41, -79, -70, -58, -79, 110, -78, -66, -48, -63, -39, -24, -57, -57, -75, -72, -65;
/M: SY='E';  M= -54, -79, -44,  85, -83,  72, -61, -87, -52, -81, -74, -53, -61, -46, -62, -53, -64, -80, -77, -75;
/M: SY='L';  M= -67, -69, -85, -77, -40, -86, -68, -32, -78,  92, -28, -84, -84, -71, -75, -77, -63, -39, -71, -53;
/M: SY='Q';  M= -59, -85, -54, -34, -90, -67, -47, -76, -39, -71, -57, -50, -66, 131, -40, -48, -62, -77, -72, -61;
/M: SY='L';  M= -67, -69, -85, -77, -40, -86, -68, -32, -78,  92, -28, -84, -84, -71, -75, -77, -63, -39, -71, -53;
/M: SY='S';  M= -41, -64, -56, -57, -74, -49, -59, -74, -57, -77, -71, -44, -64, -48, -61, 109, -35, -66, -82, -66;
/M: SY='L';  M= -67, -69, -85, -77, -40, -86, -68, -32, -78,  92, -28, -84, -84, -71, -75, -77, -63, -39, -71, -53;
/M: SY='D';  M= -65, -81,  99,  74, -86, -69, -53, -86, -49, -81, -79, -42, -62, -45, -58, -56, -59, -80, -93, -72;
/M: SY='Q';  M= -59, -85, -54, -34, -90, -67, -47, -76, -39, -71, -57, -50, -66, 131, -40, -48, -62, -77, -72, -61;
/M: SY='V';  M=  33, -68, -80, -75, -56, -76, -82,  57, -73, -41, -43, -74, -75, -73, -76, -62, -53,  77, -81, -62;
/M: SY='S';  M=  35, -63, -58, -58, -73, -53, -63, -68, -58, -72, -66, -48, -63, -53, -63,  85,  56, -59, -82, -67;
/M: SY='T';  M=  47, -63, -65, -63, -67, -61, -70, -49, -62, -59, -57, -56, -66, -61, -67,  43,  65,  44, -83, -66;
/M: SY='S';  M=  27, -63, -58, -58, -73, -52, -62, -69, -58, -72, -67, -47, -63, -52, -63,  90,  50, -60, -82, -67;
/M: SY='K';  M= -63, -77, -55, -41, -79, -70, -58, -79, 110, -78, -66, -48, -63, -39, -24, -57, -57, -75, -72, -65;
/M: SY='P';  M= -54, -76, -66, -60, -73, -64, -69, -54, -63, -68, -62, -63,  96, -62, -71,  58, -49,  42, -82, -72;
/M: SY='Q';  M=  21, -74, -59, -49, -80, -61, -60, -71, -53, -73, -63, -54,  66,  80, -57,  43,  34, -67, -78, -68;
/M: SY='F';  M= -72, -74,  43,  30, 107, -78, -63, -57, -67, -49, -57, -64, -77, -70, -70, -68, -65, -60, -50, -29;
/M: SY='S';  M= -43, -63, -56, -57, -73, -52, -60, -70, -57, -74, -68, -45, -63, -51, -62,  99,  50, -62, -84, -66;
/M: SY='W';  M= -70,  91, -81, -77, -33, -76, -57, -65, -70, -61, -60, -77, -84, -69, -70, -70, -70, -69, 127, 103;
/M: SY='R';  M= -62, -73, -55, -55, -74, -68, -54, -73, -35, -73, -64,  58, -70, -47,  90, -49,  61, -68, -82, -65;
/M: SY='T';  M= -46, -62, -56, -59, -70, -58, -63, -65, -57, -69, -65, -45, -61, -55, -63,  78,  89, -57, -85, -66;
/M: SY='P';  M=  26, -73, -62, -57, -78, -59, -66, -70, -60, -76, -67, -58,  92, -59, -68,  55,  35, -66, -81, -74;
/M: SY='M';  M= -52, -66, -68, -65, -56, -63, -60, -48, -64,  43,  84, -58, -70, -56, -65,  77, -47, -51, -77, -58;
/M: SY='T';  M= -50, -63, -51, -59, -71, -58, -59, -66, -55, -71, -65,  58, -63, -55, -62,  59,  87, -59, -88, -67;
/I:         I=-45; MI=0; MD=-92; IM=0; DM=-92;
/M: SY='T';  M= -54, -66, -59, -59, -70, -68, -68, -61, -58, -67, -62, -51,  60, -63, -67, -40, 106, -55, -86, -68;
/M: SY='S';  M= -48, -67, -67, -65, -62, -62, -65,  29, -64, -51,  63, -56, -68, -57, -67,  82, -44,  38, -81, -61;
/M: SY='Q';  M= -54, -72, -55, -44, -79, -65, -55, -69, -47, -69, -60, -48, -63, 104, -50,  30,  70, -65, -78, -63;
/M: SY='E';  M= -62, -81,  67,  98, -85, -72, -53, -85, -44, -79, -76, -50, -58, -38, -54, -56, -60, -78, -85, -73;
/M: SY='N';  M=  39, -64, -47, -58, -74, -54, -54, -68, -54, -73, -65,  93, -67, -55, -61, -41,  65, -62, -88, -70;
/M: SY='R';  M= -67, -83, -63, -51, -76, -77, -52, -83, -24, -75, -64, -56, -75, -40, 117, -61, -66, -76, -76, -62;
/M: SY='K';  M= -63, -78, -56, -43, -78, -71, -57, -80, 101, -77, -65, -49, -65, -40,  53, -58, -59, -75, -73, -65;
/M: SY='P';  M= -54, -74, -69, -68, -66,  49, -71, -51, -68,  18, -55, -63,  66, -66, -74,  27, -56,  36, -78, -69;
/M: SY='A';  M=  62, -68, -73, -70, -65,  37, -76,  48, -69, -54, -52, -64, -70, -67, -74, -52, -56,  31, -76, -67;
/M: SY='K';  M= -63, -77, -55, -41, -79, -70, -58, -79, 110, -78, -66, -48, -63, -39, -24, -57, -57, -75, -72, -65;
/M: SY='S';  M= -50, -71, -64, -60, -71, -61, -67, -54, -62, -67, -62, -58,  76, -59, -68,  77, -45,  42, -83, -69;
/M: SY='R';  M= -65, -80, -59, -46, -77, -73, -55, -81,  84, -77, -65, -52, -68, -40,  86, -59, -61, -75, -74, -64;
/M: SY='N';  M= -59, -66, -58, -66, -58, -68, -61, -43, -62,  39, -47,  74, -73, -62, -67, -52,  55,  38, -85, -63;
/M: SY='S';  M= -46, -66, -58, -62, -74,  43, -64, -72, -60, -74, -68, -46, -63, -56, -66,  78,  65, -64, -82, -68;
/M: SY='K';  M= -56, -74, -57, -47, -77, -64, -57, -78,  83, -77, -67, -48, -65, -42,  52,  55, -51, -72, -75, -65;
/M: SY='M';  M= -51, -65, -68, -66, -60, -67, -64, -42, -63, -47,  94, -58, -68, -59, -66,  55,  49,  44, -82, -59;
/M: SY='K';  M= -63, -77, -55, -41, -79, -70, -58, -79, 110, -78, -66, -48, -63, -39, -24, -57, -57, -75, -72, -65;
/M: SY='T';  M= -46, -62, -56, -58, -71, -58, -63, -66, -57, -70, -65, -45, -61, -55, -63,  81,  86, -58, -85, -66;
/M: SY='K';  M= -63, -77, -55, -41, -79, -70, -58, -79, 110, -78, -66, -48, -63, -39, -24, -57, -57, -75, -72, -65;
/M: SY='P';  M= -55, -70, -66, -62, -62, -66, -66, -54, -64,  41, -52, -60,  66, -61, -69,  55,  49, -55, -79, -65;
/M: SY='R';  M= -67, -83, -63, -51, -76, -77, -52, -83, -24, -75, -64, -56, -75, -40, 117, -61, -66, -76, -76, -62;
/M: SY='T';  M= -55, -63, -61, -63, -61, -71, -68, -52, -61,  26, -51, -52, -63, -63, -67, -41, 106, -48, -84, -63;
/M: SY='N';  M= -51, -66, -43, -57, -76, -50, -49, -75, -52, -81, -70,  98, -68, -49, -59,  77, -41, -72, -89, -69;
/M: SY='P';  M= -66, -92, -67, -55, -86, -68, -70, -74, -63, -84, -70, -73, 128, -66, -75, -64, -59, -79, -79, -83;
/M: SY='Y';  M= -71, -82, -70, -74, -19, -78, -37, -56, -65, -53, -50, -72, -83, -61, -62, -66, -65, -62, -27, 135;
/M: SY='P';  M= -60, -85, -64, -56, -83, -64, -67, -74, -62, -83, -70, -66, 118, -62, -72,  42, -53, -76, -80, -79;
/I:         I=-42; MD=-85;
/M: SY='P';  M= -91,-116, -89, -72,-115, -95, -86,-102, -79,-105, -92, -89,  75,  69, -84, -84, -88,-106,-104,-100; D=-42;
/I:         I=-42; MI=0; MD=-85; IM=0; DM=-85;
/M: SY='Q';  M= -57, -78, -55, -39, -83, -67, -51, -71, -43, -69, -58, -49, -65, 120, -45, -45,  54, -70, -75, -62;
/M: SY='Y';  M= -71, -82, -70, -74, -19, -78, -37, -56, -65, -53, -50, -72, -83, -61, -62, -66, -65, -62, -27, 135;
/M: SY='S';  M= -47, -67, -58, -57, -75, -56, -63, -70, -58, -75, -68, -49,  60, -54, -65,  85,  56, -64, -83, -69;
/M: SY='S';  M= -45, -69, -59, -65, -78,  72, -64, -81, -62, -81, -73, -47, -66, -56, -68,  82, -48, -74, -78, -71;
/M: SY='F';  M= -76, -71, -88, -84, 122, -83, -68, -49, -79, -40, -51, -77, -86, -90, -76, -74, -67, -54, -40, -19;
/M: SY='H';  M= -65, -83, -62, -51, -70, -73,  94,  47, -56, -59, -52, -56,  59,  80, -57, -59, -62, -57, -81, -55;
/M: SY='M';  M= -54, -67, -65, -67, -64,  42, -64, -55, -62, -53,  94, -53, -64, -62, -68, -47,  84, -53, -80, -62;
/M: SY='D';  M= -65, -81, 106,  60, -87, -67, -53, -86, -51, -82, -80, -40, -63, -48, -60, -56, -58, -81, -96, -71;
/M: SY='R';  M= -65, -80, -59, -46, -77, -73, -55, -81,  84, -77, -65, -52, -68, -40,  86, -59, -61, -75, -74, -64;
/M: SY='S';  M= -53, -69, -64, -60, -61, -63, -60, -58, -51,  41, -52, -56, -72, -51,  55,  77, -48, -58, -77, -61;
/M: SY='E';  M= -62, -81,  60, 101, -85, -73, -53, -85, -44, -78, -75, -51, -58, -38, -54, -56, -60, -78, -85, -73;
/M: SY='C';  M= -50, 126, -67, -68, -73, -62, -69, -76, -66, -73, -70, -55, -76, -64, -71,  77, -47, -66, -91, -74;
/M: SY='D';  M= -53, -73,  88, -44, -82,  29, -58, -82, -58, -82, -77, -40, -66, -54, -64,  67, -49, -76, -89, -70;
/M: SY='Q';  M= -62, -84, -54, -38, -82, -68,  94, -78, -44, -70, -56, -48, -67, 118, -43, -51, -63, -80, -79, -53;
/M: SY='D';  M= -66, -77,  87, -49, -50, -73, -54, -53, -63,  18, -56, -52, -74, -61, -66, -62, -59,  22, -66,  73;
/M: SY='S';  M= -45, -70, -60, -66, -79,  77, -65, -82, -63, -82, -73, -47, -66, -57, -69,  77, -50, -75, -78, -72;
/M: SY='Q';  M= -56, -75, -50, -49, -81, -57, -52, -75, -50, -78, -66,  74,  59,  77, -55,  49, -49, -75, -82, -69;
/M: SY='W';  M= -76,-101,-103, -80, -40, -74,-103, -73, -72, -71, -74, -96, -79, -72, -76, -82, -88, -88, 179, -27;
/M: SY='G';  M= -57, -79, -62, -58, -80,  72, -62, -85,  50, -81, -69, -51, -69, -51,  66, -54, -65, -79, -74, -70;
/M: SY='G';  M=  27, -71, -64, -71, -79,  89, -70, -80, -67, -79, -70, -51, -66, -65, -74, -46,  33, -72, -76, -75;
/M: SY='S';  M= -43, -63, -56, -57, -72, -53, -61, -70, -57, -74, -68, -45, -62, -51, -62,  98,  56, -62, -84, -66;
/M: SY='P';  M= -66, -92, -67, -55, -86, -68, -70, -74, -63, -84, -70, -73, 128, -66, -75, -64, -59, -79, -79, -83;
/M: SY='P';  M= -63, -72, -71, -65, -56, -76, -69, -47, -68,  60, -44, -69,  76, -67, -73, -60,  54, -51, -77, -63;
/M: SY='T';  M=  26, -63, -64, -63, -64, -66, -64, -53, -60, -53,  84, -53, -63, -60, -65, -42,  94, -49, -82, -62;
/M: SY='D';  M= -60, -73,  88, -43, -81, -56, -50, -80, -52, -83, -76,  83, -69, -52, -60,  35, -49, -78, -97, -70;
/M: SY='T';  M=  50, -62, -60, -60, -71, -58, -66, -63, -59, -67, -62, -50, -62, -58, -65,  44,  87, -54, -83, -67;
/M: SY='A';  M=  93, -62, -70, -62, -72, -52, -71, -55, -64, -62, -58, -64, -68, -61, -68, -44, -52,  24, -77, -70;
/M: SY='S';  M=  50, -62, -59, -58, -73, -53, -64, -67, -59, -71, -65, -49, -63, -54, -64,  78,  56, -58, -82, -67;
/M: SY='P';  M= -65, -85, -57, -56, -84, -63, -62, -74, -59, -84, -70,  63, 116, -62, -70, -58, -56, -79, -83, -80;
/M: SY='Q';  M= -61, -87, -58, -39, -89, -67, -53, -75, -45, -74, -61, -55,  76, 116, -48, -52, -61, -78, -74, -66;
/I:         I=-36; MI=0; MD=-73; IM=0; DM=-73;
/M: SY='E';  M=  20, -76, -46,  85, -70, -72, -60, -65, -52,  25, -58, -64,  44, -46, -60, -58, -60, -63, -77, -69;
/M: SY='Q';  M= -63, -77,  38,  32, -65, -74, -55, -56, -52,  49, -48, -57, -70,  89, -55, -59, -61, -60, -76, -60;
/M: SY='Q';  M= -56, -78, -51,  46, -81, -66, -52, -79, -38, -74, -65, -51, -65,  81,  63,  48, -55, -74, -77, -65;
/M: SY='P';  M= -64, -80, -56, -52, -75, -65, -57, -66, -55,  10, -59,  63,  92,  63, -61, -56, -57, -71, -80, -71;
/M: SY='H';  M= -61,  84, -60, -63, -72,  49, 121, -86, -64, -73, -62, -49, -73, -58, -63, -57, -67, -81, -93, -52;
/M: SY='S';  M= -44, -67, -49,  45, -76, -53, -58, -76, -53, -77, -71, -46, -62, -45, -59,  99, -39, -68, -82, -67;
/M: SY='E';  M= -57, -81, -42,  85, -85,  36, -54, -83, -45, -77, -68, -53, -60,  77, -52, -53, -62, -78, -76, -70;
/M: SY='H';  M=  19, -71, -55, -60, -67, -61,  94,  41, -59, -62, -55,  64, -70, -54, -61,  34, -52, -55, -87, -56;
/M: SY='S';  M= -50, -71,  40,  66, -79, -59, -56, -79, -51, -78, -73, -46, -61, -44, -58,  82, -45, -71, -84, -69;
/M: SY='D';  M=  20, -72,  69,  52, -73, -63, -58, -69, -55,  10, -64, -49, -65, -50, -62,  42, -53, -65, -84, -68;
/M: SY='S';  M= -53, -66, -68, -66, -53, -65, -64, -47, -67,  65, -43, -61, -73, -59, -68,  77, -48, -50, -76, -59;
/M: SY='C';  M= -64, 121, -83, -79, -52, -81, -74, -48, -78,  65, -43, -75, -88, -77, -79, -70, -62, -50, -83, -64;
/M: SY='Y';  M=  45, -72, -72, -70, -35, -69, -51, -48, -66, -53, -51, -70, -77, -63, -66, -58, -58,  37, -45, 107;
/M: SY='Y';  M= -60, -72, -64, -68, -39,  21, -51, -61, -62, -60, -56, -57, -70, -62, -65, -49,  76, -59, -48, 102;
/M: SY='P';  M= -67, -88, -65, -53, -81, -72, -61, -78, -40, -80, -67, -64, 100, -52,  85, -62, -62, -78, -78, -72;
/M: SY='Q';  M= -55, -75, -57, -45, -80, -64, -56, -70, -48, -71, -61, -50,  45,  99, -52,  35,  55, -68, -78, -65;
/M: SY='Y';  M= -73, -77, -78, -78,  92, -80, -49, -53, -71, -47, -50, -74, -85, -72, -68, -70, -66, -58, -33, 108;
/M: SY='S';  M= -44, -67, -57, -56, -76, -51, -60, -74, -58, -78, -71, -47,  44, -50, -63, 102, -38, -68, -82, -68;
/M: SY='D';  M= -67, -74,  87, -49, -57, -74, -60, -50, -66,  65, -46, -54, -75, -62, -69, -66, -60, -55, -83, -60;
/M: SY='P';  M= -67, -89, -66, -54, -83, -70, -64, -76, -48, -82, -69, -68, 114, -57,  62, -63, -61, -78, -78, -77;
/M: SY='F';  M= -62, -71, -72, -67,  95, -70, -62, -60, -56, -54, -58, -61, -77, -63,  49,  54, -56, -61, -55, -35;
/M: SY='S';  M= -41, -64, -56, -57, -74, -49, -59, -74, -57, -77, -71, -44, -64, -48, -61, 109, -35, -66, -82, -66;
/M: SY='Y';  M= -69, -75, -77, -75, -28, -82, -49, -43, -71,  61, -38, -77, -84, -65, -68, -71, -64, -50, -42, 107;
/M: SY='C';  M= -65, 121, -64, -64, -69, -74, 121, -82, -66, -69, -60, -52, -79, -61, -64, -61, -65, -75,-102, -53;
/M: SY='Y';  M= -71, -82, -70, -74, -19, -78, -37, -56, -65, -53, -50, -72, -83, -61, -62, -66, -65, -62, -27, 135;
/M: SY='G';  M= -49, -77, -64, -76, -83, 103, -71, -91, -70, -86, -75, -50, -68, -67, -77, -49, -68, -84, -74, -78;
/I:         I=-45; MD=-92;
/M: SY='H';  M= -83, -91, -74, -72, -72, -88, 121, -78, -77,  24, -59, -64, -87, -66, -71, -77, -80, -81,-106, -54; D=-45;
/I:         I=-45; MI=-92; IM=-92; DM=-92;
/M: SY='F';  M= -74, -75, -83, -76, 113, -80, -68, -53, -75, -46, -54, -76,  59, -84, -76, -72, -66, -58, -46, -26;
/M: SY='P';  M=  45, -77, -70, -60, -70, -65, -69, -60, -65,  25, -56, -72, 100, -65, -73, -58, -58, -60, -76, -72;
/M: SY='M';  M= -62, -67, -77, -72, -47, -79, -64, -37, -70,  69,  85, -71, -75, -65, -70, -64,  48, -42, -75, -54;
/M: SY='D';  M= -66, -81, 110,  48, -87, -66, -53, -86, -52, -83, -81, -38, -64, -49, -61, -56, -58, -82, -98, -71;
/M: SY='H';  M= -52, -71,  52, -49, -75, -57,  94, -79, -57, -76, -67, -42, -66, -49, -59,  82, -46, -74, -91, -56;
/M: SY='H';  M= -60, -76, -54, -54, -69, -64, 135, -82, -58, -71, -58, -43, -68, -47, -54,  55, -56, -79, -97, -43;
/M: SY='H';  M= -59, -73, -70, -63, -62, -79,  80, -39, -51, -52, -50, -63, -76, -58,  62, -63, -57,  76, -87, -56;
/M: SY='F';  M= -66, -68, -78, -75,  72, -81, -68, -41, -73,  64, -39, -72, -78, -73, -73, -65,  48, -45, -62, -41;
/M: SY='S';  M= -44, -64, -62, -61, -68, -56, -65, -51, -61, -63, -61, -51, -67, -55, -65,  95, -39,  50, -84, -65;
/M: SY='S';  M= -49, -69, -43,  58, -77, -55, -54, -77, -50, -78, -71,  58, -63, -44, -57,  82, -43, -71, -84, -69;
/M: SY='K';  M= -62, -79,  39,  67, -82, -71, -56, -82,  83, -78, -70, -48, -61, -39, -35, -57, -58, -76, -78, -69;
/M: SY='K';  M= -65, -77, -62, -49, -67, -75, -58, -66,  83,  25, -55, -55, -70, -44,  64, -61, -61, -65, -73, -62;
/M: SY='H';  M= -66, -85, -60, -51, -59, -70,  94, -73, -55, -69, -58, -57,  76,  70, -56, -59, -63, -76, -65,  66;
/M: SY='M';  M= -55, -69, -75, -73,  68,  22, -67, -44, -69, -47,  69, -64, -74, -68, -71,  41, -54,  43, -65, -45;
/M: SY='H';  M= -67, -74, -67, -63, -54, -76, 117, -51, -65,  43,  84, -57, -74, -55, -60, -66, -64, -56, -84, -44;
/M: SY='P';  M= -62, -81, -64, -57, -80, -68, -69, -69, -61, -77, -67, -64, 114, -65, -73, -54,  61, -69, -82, -78;
/M: SY='H';  M=  49, -71, -58, -49, -77, -57,  80, -74, -53, -71, -60, -50, -66,  77, -54,  49, -52, -67, -80, -58;
/M: SY='K';  M=  46, -71, -60, -51, -76, -60, -59, -75,  60, -74, -65, -52, -67, -46,  57,  43, -52, -66, -76, -66;
/I:         I=-38; MD=-78;
/M: SY='Y';  M=-101,-103,-107,-106,  71,-108, -79, -80,-100, -73, -78,-102,-112,-102, -97, -98, -94, -85, -62,  73; D=-38;
/I:         I=-38; MI=-78; MD=-78; IM=-78; DM=-78;
/M: SY='G';  M= -66, -92, -66,  43, -97,  76, -79,-103, -74, -97, -88, -66, -78, -69, -82, -65, -80, -96, -89, -90; D=-38;
/I:         I=-38; DM=-78;
/M: SY='Q';  M= -67, -92, -68, -53, -99, -75, -64, -89, -57, -86, -74, -62, -80, 104, -59,  41, -67, -88, -88, -76; D=-38;
/I:         I=-38; DM=-78;
/M: SY='C';  M= -64, 121, -73, -66, -78, -72, -75, -76, -69, -76, -70, -70, 100, -74, -79, -64, -60, -72, -88, -83;
/M: SY='Q';  M= -59, -83, -42,  81, -87, -71, -50, -80, -40, -73, -64, -53, -61, 105, -45, -52, -61, -77, -76, -66;
/I:         I=-45; MI=0; MD=-92; IM=0; DM=-92;
/M: SY='G';  M= -50, -75, -62, -65, -79,  80, -64, -85, -53, -82, -72, -50, -68, -56,  49,  49, -58, -78, -76, -72;
/M: SY='S';  M= -45, -69, -59, -65, -78,  72, -64, -81, -62, -81, -73, -47, -66, -56, -68,  82, -48, -74, -78, -71;
/M: SY='P';  M= -65,  84, -68, -58, -80, -72, -66, -77, -50, -78, -68, -67, 100, -60,  62, -63, -61, -75, -82, -76;
/M: SY='C';  M= -61, 154, -81, -81, -71, -77, -81, -78, -77, -69, -69, -67, -92, -85, -83, -64, -61, -66,-101, -82;
/M: SY='E';  M= -60, -80, -35, 103, -83, -75, -54, -83,  45, -77, -71, -55, -57, -35, -44, -57, -60, -76, -78, -72;
/M: SY='V';  M=  68, -64, -75, -68, -63, -64, -77, -35, -69, -50, -50, -70, -73, -68, -72, -52, -51,  77, -82, -66;
/M: SY='A';  M=  73, -68, -66, -67, -79,  72, -70, -75, -66, -75, -67, -56, -67, -63, -72, -45, -59, -64, -75, -74;
/M: SY='R';  M= -67, -83, -63, -51, -76, -77, -52, -83, -24, -75, -64, -56, -75, -40, 117, -61, -66, -76, -76, -62;
/M: SY='Y';  M= -74, -76, -79, -79,  96, -80, -50, -52, -72, -46, -50, -74, -85, -74, -69, -70, -66, -57, -34, 103;
/M: SY='F';  M= -76, -71, -88, -84, 122, -83, -68, -49, -79, -40, -51, -77, -86, -90, -76, -74, -67, -54, -40, -19;
/M: SY='L';  M= -69, -69, -85, -78,  62, -85, -68, -35, -78,  81, -32, -82, -85, -74, -75, -77, -64, -42, -62, -42;
/M: SY='S';  M= -45, -69, -59, -65, -78,  72, -64, -81, -62, -81, -73, -47, -66, -56, -68,  82, -48, -74, -78, -71;
/M: SY='T';  M=  20, -61, -59, -60, -68, -65, -68, -59, -58, -64, -60, -48, -60, -61, -66, -36, 109, -51, -86, -66;
/M: SY='P';  M= -67, -78, -75, -65, -56, -77, -69, -47, -70,  65, -43, -78,  96, -69, -75, -70, -61, -54, -75, -65;
/M: SY='Q';  M= -62, -88, -59, -42, -88, -68, -56, -75, -48, -76, -62, -58,  92, 107, -52, -54, -61, -78, -75, -69;
/M: SY='A';  M=  65, -66, -63, -58, -76, -55, -67, -68, -60, -72, -65, -57,  60, -58, -67,  49,  35, -59, -79, -71;
/M: SY='S';  M= -45, -69, -59, -65, -78,  72, -64, -81, -62, -81, -73, -47, -66, -56, -68,  82, -48, -74, -78, -71;
/M: SY='R';  M= -55, -78, -63, -60, -78,  64, -60, -84, -41, -79, -69, -52, -71, -50,  85,  28, -61, -77, -76, -68;
/M: SY='E';  M= -61, -81,  41, 106, -84, -74, -53, -85, -43, -78, -74, -53, -57, -36, -53, -56, -60, -78, -83, -73;
/M: SY='C';  M=  33, 126, -74, -68, -76, -67, -75, -74, -70, -72, -68, -68,  73, -73, -77, -58, -59, -66, -89, -80;
/M: SY='W';  M= -69, -91, -71, -55, -56, -71,  86, -77, -57, -70, -63, -63, -73,  80, -57, -64, -74, -84, 146, -37;
/M: SY='W';  M= -76,-101,-103, -80, -40, -74,-103, -73, -72, -71, -74, -96, -79, -72, -76, -82, -88, -88, 179, -27;
/M: SY='H';  M= -59, -79, -58, -63, -74,  72, 121, -88, -63, -76, -63, -46, -69, -55, -62, -54, -68, -85, -87, -51;
/M: SY='Y';  M=  33,  69, -66, -66, -44, -62, -52, -65, -64, -64, -59, -60, -74, -59, -65,  55, -52, -61, -52,  95;
/M: SY='A';  M=  85, -66, -67, -57, -76, -55, -64, -69, -48, -69, -62, -61, -69, -53,  62, -46, -55, -57, -76, -69;
/M: SY='N';  M=  46, -68, -47, -56, -76, -54, -50, -74, -45, -77, -66,  98, -72, -50,  49, -46, -51, -69, -85, -70;
/M: SY='S';  M=  47, -66, -60, -57, -76, -52, -63, -71, -59, -75, -68, -52,  51, -54, -65,  85, -43, -63, -80, -70;
/M: SY='L';  M= -60, -68, -84, -77, -46, -85, -75, -26, -77,  69, -34, -81, -82, -73, -75, -72, -57,  69, -78, -57;
/M: SY='V';  M= -58, -72, -78, -70, -57, -79, -77, -31, -72,  28, -45, -78,  73, -73, -76, -67, -55,  77, -82, -65;
/M: SY='P';  M= -67, -84, -71, -60, -68, -72, -69, -58, -66,  38, -54, -76, 114, -68, -75, -67, -60, -64, -77, -73;
/I:         I=-38; MD=-78;
/M: SY='T';  M= -62, -75, -73, -74, -72, -74, -76, -66, -73,  25, -64, -64, -78, -69, -77,  58,  61, -64, -92, -74; D=-38;
/I:         I=-38; MI=0; MD=-78; IM=0; DM=-78;
/M: SY='K';  M= -64, -83, -66, -58, -88, -72, -70, -88,  78, -89, -79, -58, -74, -54, -46,  57, -59, -83, -87, -77; D=-38;
/I:         I=-38; DM=-78;
/M: SY='S';  M=  47, -63, -59, -57, -75, -49, -61, -71, -58, -74, -68, -48, -64, -51, -63,  95, -39, -62, -80, -67;
/M: SY='S';  M= -41, -64, -56, -57, -74, -49, -59, -74, -57, -77, -71, -44, -64, -48, -61, 109, -35, -66, -82, -66;
/M: SY='P';  M= -66, -92, -67, -55, -86, -68, -70, -74, -63, -84, -70, -73, 128, -66, -75, -64, -59, -79, -79, -83;
/M: SY='E';  M=  49, -76, -46,  80, -82, -65, -61, -75, -51, -75, -68, -62,  66, -46, -60, -53, -57, -68, -79, -75;
/M: SY='K';  M= -55, -71, -50, -48, -77, -59, -55, -77,  83, -79, -68,  58, -65, -44, -37,  55, -48, -73, -79, -67;
/M: SY='N';  M= -61, -73, -46, -58, -78,  37, -50, -80, -43, -82, -69,  98, -73, -50,  62, -49, -55, -79, -85, -70;
/I:         I=-45; MD=-92;
/M: SY='E';  M= -85,-100,  51,  57, -92, -95, -78, -88, -73,   8, -82, -74, -86, -68, -81, -82, -82, -88,-105, -89; D=-45;
/I:         I=-45; MI=-92; IM=-92; DM=-92;
/M: SY='S';  M=  46, -70, -66, -62, -69, -59, -69,  47, -64, -60, -57, -59,  51, -59, -69,  63, -48, -48, -78, -67;
/M: SY='H';  M= -69, -81, -60,  30,  55, -75,  87, -66, -61, -60, -56, -62,  51, -57, -62, -64, -65, -69, -53,  80;
/M: SY='E';  M= -61, -82, -34, 106, -84, -75, -55, -83, -44, -78, -73, -59,  45, -37, -54, -57, -60, -77, -80, -75;
/M: SY='N';  M= -56, -76, -51, -53, -82,  37, -54, -78, -52, -80, -68,  71,  51,  70, -58,  29, -53, -77, -81, -71;
/M: SY='S';  M= -49, -71, -63, -59, -72, -60, -66, -56, -62, -68, -63, -57,  76, -58, -68,  80, -44,  36, -83, -70;
/M: SY='M';  M=  26, -65, -74, -68, -59, -66, -67, -36, -66, -44,  91, -65, -71, -62, -68,  42, -49,  62, -81, -60;
/M: SY='P';  M= -61, -75, -53, -57, -78, -62, -59, -70, -57, -78, -68,  74,  96, -60, -67, -50,  55, -70, -86, -75;
/M: SY='H';  M=  19, -75, -56, -50, -73, -66, 117, -75, -53, -68, -56, -47, -67,  70, -52, -49,  40, -71, -88, -49;
/M: SY='I';  M=  49, -70, -79, -74, -57, -73, -80,  78, -73, -42, -43, -72, -73, -70, -76, -60, -55,  46, -77, -62;
/M: SY='R';  M=  54, -71, -64, -55, -75, -64, -59, -72, -37, -70, -62, -57, -70, -48,  90, -49,  33, -63, -77, -66;
/M: SY='H';  M= -54, -72, -54, -55, -71, -59, 121, -80, -57, -72, -61, -43, -67, -48, -56,  77, -50, -75, -92, -48;
/I:         I=-45; MI=0; MD=-92; IM=0; DM=-92;
/M: SY='H';  M= -59, -74, -50, -57, -73,  23, 117, -82, -57, -75, -62,  64, -69, -50, -57,  34, -56, -80, -93, -52;
/M: SY='L';  M= -60, -71, -71, -64, -53, -74, -61, -48, -52,  65, -42, -65, -77, -56,  62,  41, -57, -52, -74, -58;
/M: SY='I';  M=  39, -68, -80, -74, -53, -75, -78,  57, -73,  29, -40, -74, -75, -71, -75, -62, -55,  55, -77, -60;
/M: SY='H';  M= -66, -85, -57, -49, -76, -69, 120, -80, -55, -73, -59, -51,  76,  64, -55, -58, -64, -82, -88, -51;
/M: SY='N';  M= -52, -69, -52, -65, -72,  50, -58, -59, -59, -70, -64,  83, -71, -58, -66,  35, -50,  36, -85, -70;
/M: SY='Y';  M= -69, -83, -67, -62, -37, -77, -43, -67, -41, -62, -56, -64, -79, -50,  85, -64, -66, -68, -44, 107;
/M: SY='E';  M= -54, -79, -44,  85, -83,  72, -61, -87, -52, -81, -74, -53, -61, -46, -62, -53, -64, -80, -77, -75;
/M: SY='H';  M=  72, -69, -60, -57, -72, -58, 117, -74, -60, -68, -57, -52, -68, -53, -59, -48, -59, -65, -87, -52;
/M: SY='W';  M= -70, -96, -80, -65, -59, -71, -83, -74, -67, -78, -72, -83, 100, -69, -76, -71, -70, -83, 146, -48;
/M: SY='D';  M=  25, -74,  88, -40, -82, -60, -57, -79,  49, -79, -73, -43, -65, -50, -51,  28, -53, -72, -87, -69;
/M: SY='E';  M=  49, -73, -44,  80, -80, -65, -59, -77,  50, -74, -67, -56, -60, -41, -46, -51, -57, -67, -77, -71;
/M: SY='D';  M=  48, -72,  87, -47,  60, -62, -61, -69, -62, -65, -67, -49, -70, -62, -67, -54, -58, -65, -73, -52;
/M: SY='S';  M=  22, -64, -61, -60, -70, -53, -64, -58, -60, -67, -63, -50, -66, -53, -64,  94, -40,  29, -82, -66;
/I:         I=-21; MD=-42;
/M: SY='A';  M=  63, -78, -88, -81, -81, -75, -90, -56, -82, -69, -68, -83, -86, -81, -86, -64, -67,  49, -95, -83; D=-21;
/I:         I=-21; MD=-42;
/M: SY='V';  M= -72, -82, -99, -92, -64,-100, -94, -38, -91,  33, -52, -95, -96, -90, -91, -85, -69,  72, -97, -74; D=-21;
/I:         I=-21; MD=-42;
/M: SY='S';  M= -63, -84,  57, -62, -93, -69, -72, -93, -71, -95, -90, -56, -80, -65, -77,  77, -57, -86,-104, -83; D=-21;
/I:         I=-21; MD=-42;
/M: SY='S';  M= -56, -79, -71, -72, -89, -64, -74, -89, -72, -93, -86, -59, -79, -64, -76,  93, -51, -81, -98, -81; D=-21;
/I:         I=-21; MD=-42;
/M: SY='P';  M=  31, -96, -82, -72, -98, -77, -85, -86, -78, -94, -83, -85,  98, -79, -88, -71, -72, -85, -93, -95; D=-21;
/I:         I=-21; MD=-42;
/M: SY='P';  M= -82,-103,  64, -59,-102, -82, -78, -93, -75,-100, -90, -69,  91, -76, -86, -75, -74, -96,-102, -93; D=-21;
/I:         I=-21; MD=-42;
/M: SY='D';  M= -82,-100,  83, -54,-102, -81, -74, -96, -73,-100, -93, -61,  72, -74, -83, -74, -73, -97,-108, -90; D=-21;
/I:         I=-21; MD=-42;
/M: SY='G';  M= -64, -92, -80, -91, -98,  88, -86,-106, -85,-101, -90, -65, -83, -82, -92, -64, -83, -99, -89, -93; D=-21;
/I:         I=-21; MI=0; MD=-42; IM=0; DM=-42;
/M: SY='S';  M= -56, -79, -71, -72, -89, -64, -74, -89, -72, -93, -86, -59, -79, -64, -76,  93, -51, -81, -98, -81; D=-21;
/I:         I=-21; DM=-42;
/M: SY='M';  M=  67, -79, -88, -79, -81, -71, -79, -68, -79, -65,  83, -80, -83, -74, -81, -64, -70, -64, -90, -78; D=-21;
/I:         I=-21; DM=-42;
/M: SY='S';  M= -47, -69, -58, -55, -75, -56, -57, -76, -44, -77, -69, -47, -67, -46,  66,  94, -42, -69, -80, -65;
/M: SY='R';  M= -65, -82,  53,  59, -80, -74, -53, -84, -33, -77, -70, -51, -67, -40,  90, -59, -62, -78, -81, -67;
/M: SY='S';  M= -49, -66, -63, -63,  71, -57, -61, -65, -62, -63, -64, -51, -69, -57, -65,  94, -43, -62, -65, -46;
/M: SY='G';  M= -48,  69, -64, -71, -79,  84, -69, -84, -67, -81, -73, -51, -70, -64, -74,  49, -57, -77, -79, -75;
/M: SY='D';  M= -65, -83,  88,  62, -86, -68, -57, -83, -52, -82, -77, -48,  66, -49, -62, -58, -59, -80, -89, -74;
/M: SY='R';  M= -67, -83,  68, -44, -79, -73, -52, -84, -31, -78, -69, -49, -73, -44, 102, -59, -63, -78, -82, -65;
/M: SY='Y';  M= -68, -77, -70, -70,  57, -76, -49, -57, -66, -55, -54, -68,  44, -66, -67, -60,  39, -60, -41, 106;
/M: SY='R';  M=  49, -74, -62, -51, -76, -65, -58, -76,  51, -73, -63, -56, -69, -45,  85, -53, -59, -67, -75, -66;
/M: SY='P';  M=  33, -73,  58, -50, -78, -63, -65, -70, -59, -74, -68, -52,  76, -61, -68, -48,  61, -64, -85, -73;
/M: SY='E';  M= -63, -84,  53,  83, -85, -71, -58, -81, -49, -80, -74, -55,  76, -45, -60, -58, -59, -79, -84, -76;
/M: SY='Q';  M= -54, -74, -60, -47, -69, -64, -55, -60, -51,  32, -51, -54, -69,  99, -52,  58, -52, -62, -75, -60;
/M: SY='Y';  M= -70,  84, -77, -78,  73, -79, -51, -57, -71, -51, -53, -72, -86, -72, -70, -68, -65, -60, -39, 106;
/M: SY='H';  M= -65, -86, -59, -47, -80, -70,  87, -79, -45, -75, -61, -55,  76,  77,  50, -57, -63, -79, -81, -59;
/M: SY='S';  M= -43, -64, -52, -57, -75, -49, -56, -74, -55, -78, -71,  44, -65, -49, -60, 102, -37, -68, -84, -67;
/M: SY='C';  M= -46, 102, -62, -63, -73, -56, -64, -75, -62, -75, -70, -50, -70, -56, -67,  94, -42, -66, -87, -70;
/M: SY='P';  M= -60, -87, -66, -60, -85,  53, -70, -78, -65, -85, -72, -65, 113, -67, -76, -59, -61, -80, -78, -82;
/M: SY='H';  M= -65, -79, -59, -52, -66, -71, 125, -67, -55, -56,  84, -49, -69,  64, -52, -59, -65, -70, -88, -43;
/M: SY='Y';  M= -64, -80, -45,  80, -52, -75, -49, -73,  50, -68, -63, -58, -64, -42, -46, -59, -61, -71, -56,  83;
/M: SY='P';  M= -63, -80, -63, -55, -78, -71, -63, -72, -46, -76, -66, -61,  96, -56,  65, -55,  54, -70, -80, -72;
/M: SY='S';  M= -50, -69, -42,  61, -77, -56, -53, -77, -50, -79, -71,  64, -63, -44, -57,  77, -44, -72, -85, -70;
/M: SY='K';  M= -62, -78, -46,  62, -80, -71, -57, -81,  95, -78, -68, -50, -60, -38, -30, -57, -58, -75, -74, -68;
/M: SY='I';  M= -58, -78, -71, -67, -63, -71, -74,  77, -68, -51, -50, -66,  76, -65, -75,  47, -52, -39, -77, -65;
/M: SY='E';  M=  49, -74, -39,  97, -81, -66, -57, -78, -46, -73, -69, -58, -58, -40, -55, -51, -58, -68, -79, -73;
/M: SY='T';  M= -58, -65, -57, -64, -59, -67, -61, -52, -60,  42, -49,  64, -68, -61, -66, -47,  84, -52, -84, -63;
/M: SY='L';  M= -61, -74, -72, -69, -57,  52, -65, -53, -56,  60, -45, -65, -77, -60,  55, -64, -65, -56, -73, -61;
/M: SY='I';  M=  39, -77, -75, -68, -63, -71, -77,  77, -70, -50, -49, -72,  76, -68, -77, -61, -57, -37, -76, -66;
/M: SY='R';  M=  72, -70, -66, -56, -76, -60, -60, -73, -40, -71, -62, -59, -70, -49,  85, -49, -58, -62, -76, -67;
/M: SY='A';  M=  68, -71, -63, -52, -79, -58, -66, -71,  59, -74, -64, -60,  66, -54, -50, -50, -55, -63, -75, -72;
/M: SY='T';  M=  49, -67, -62, -59, -74, -62, -69, -64, -60, -68, -62, -56,  66, -62, -68, -42,  84, -56, -82, -71;
/M: SY='Q';  M=  25, -80, -61, -47, -59, -66, -50, -68, -51, -67, -57, -59,  44,  99, -52, -52, -61, -69, -58,  73;
/M: SY='Q';  M= -64, -83, -56, -42, -79, -71,  87, -80, -37, -71, -58, -50, -70, 100,  66, -54, -64, -79, -79, -54;
/M: SY='M';  M= -57, -75, -68, -58, -66,  42, -55, -54, -57, -47, 114, -58, -69,  80, -58, -58, -62, -58, -73, -58;
/M: SY='I';  M=  49, -70, -79, -74, -57, -73, -80,  78, -73, -42, -43, -72, -73, -70, -76, -60, -55,  46, -77, -62;
/M: SY='K';  M=  25, -72, -57, -46, -78, -62, -60, -76,  95, -76, -66, -49, -63, -43, -32,  28, -53, -69, -74, -66;
/M: SY='E';  M= -62, -82, -38,  97, -81, -76, -53, -84, -35, -76, -70, -57, -60, -35,  66, -58, -62, -77, -79, -70;
/M: SY='E';  M= -62, -81,  70,  97, -85, -72, -53, -85, -45, -79, -76, -49, -58, -39, -55, -56, -60, -78, -86, -73;
/I:         I=-45; MD=-92;
/M: SY='E';  M=  18, -87, -53,  80, -93,  27, -70, -93, -61, -88, -82, -68, -71, -54, -70, -63, -72, -84, -89, -85; D=-45;
/I:         I=-45; MI=-92; IM=-92; DM=-92;
/M: SY='N';  M=  49, -65, -46, -58, -76, -50, -52, -72, -53, -77, -67,  96, -69, -52, -60,  43, -46, -67, -86, -71;
/M: SY='R';  M= -66, -82, -61, -49, -77, -75, -53, -82,  53, -76, -64, -54, -72, -40, 106, -60, -64, -76, -75, -63;
/M: SY='L';  M= -67, -69, -85, -77, -40, -86, -68, -32, -78,  92, -28, -84, -84, -71, -75, -77, -63, -39, -71, -53;
/M: SY='Q';  M=  49, -71, -58, -45, -81, -57, -55, -72, -49, -71, -61, -52, -66,  99, -51,  49, -52, -66, -75, -65;
/M: SY='L';  M= -69, -69, -85, -78,  62, -85, -68, -35, -78,  81, -32, -82, -85, -74, -75, -77, -64, -42, -62, -42;
/M: SY='R';  M=  49, -71, -63, -55, -75, -60, -58, -75, -39, -73, -64, -55, -70, -47,  85,  49, -53, -65, -77, -66;
/M: SY='R';  M= -65, -80, -59, -46, -77, -73, -55, -81,  79, -76, -65, -52, -69, -40,  90, -59, -61, -75, -74, -64;
/I:         I=-14; MD=-28;
/M: SY='A';  M=  75, -74, -83, -75, -75, -67, -81, -65, -77,  25, -61, -78, -82, -73, -80, -59, -66, -60, -86, -77; D=-14;
/I:         I=-14; MD=-28;
/M: SY='P';  M=  23, -95, -78, -68, -95, -75, -81, -83, -74, -91, -80, -82, 106, -76, -85, -69, -69, -83, -90, -92; D=-14;
/I:         I=-14; MD=-28;
/M: SY='P';  M= -68, -88, -73, -68, -90, -75, -79, -81, -72, -88, -79, -70,  92, -73, -81,  28,  48, -79, -93, -86; D=-14;
/I:         I=-14; MD=-28;
/M: SY='D';  M= -76, -92,  88,  62, -98, -80, -65, -97, -60, -93, -91, -53, -73, -56, -70, -67, -70, -92,-104, -83; D=-14;
/I:         I=-14; MD=-28;
/M: SY='C';  M= -84, 101, -90, -76,-103, -96, -86,-101, -79, -94, -87, -82,-102,  76, -81, -80, -86, -95,-109, -95; D=-14;
/I:         I=-14; MD=-28;
/M: SY='C';  M= -88, 101,-107,-103, -78,-105, -99, -74,-102,  37, -69, -99,-112,-102,-103, -94, -86, -75,-108, -90; D=-14;
/I:         I=-14; MD=-28;
/M: SY='A';  M=  75, -85, -92, -84,-100, -73, -94, -89, -87, -91, -85, -87, -91, -83, -91, -65, -76, -76,-100, -96; D=-14;
/I:         I=-14; MI=0; MD=-28; IM=0; DM=-28;
/M: SY='Y';  M= -80, -92, -89, -90, -41, -95, -61, -57, -83, -64, -63, -89, -97, -80, -81, -81, -76,  35, -53, 105; D=-14;
/I:         I=-14; DM=-28;
/M: SY='Q';  M= -76,-102, -73, -54,-104, -83, -68, -90, -60, -89, -76, -70,  59, 102, -63, -67, -76, -93, -89, -81; D=-14;
/I:         I=-14; DM=-28;
/M: SY='Q';  M= -76, -95, -76, -57, -85, -87, -67, -73, -63,  24, -62, -72, -86, 102, -62, -70, -77, -78, -87, -74; D=-14;
/I:         I=-14; DM=-28;
/M: SY='E';  M= -77,-100, -57,  76,-100, -88, -74, -95, -64, -95, -87, -78,  73, -59, -74, -74, -75, -93, -95, -92; D=-14;
/I:         I=-14; DM=-28;
/M: SY='P';  M= -65, -88, -64, -52, -84, -69, -67, -75,  49, -83, -69, -66, 116, -59, -57, -62, -59, -78, -77, -79;
/M: SY='P';  M= -60, -76, -62, -57, -77, -68, -69, -67, -60, -74, -65, -60, 104, -64, -71, -49,  80, -64, -83, -75;
/M: SY='T';  M=  19, -64, -58, -64,  61, -64, -62, -60, -60, -60, -59,  57, -68, -63, -66, -44,  80, -56, -71, -51;
/M: SY='P';  M=  40, -73, -64, -61, -80,  50, -68, -75, -63, -79, -69, -57,  76, -61, -71,  43, -54, -70, -77, -75;
/M: SY='E';  M= -62, -75, -38,  88, -70, -70, -53, -66, -48,  25, -59,  64, -64, -43, -56, -57, -57, -67, -81, -68;
/I:         I=-24; MD=-48;
/M: SY='E';  M=  32, -85, -71,  50, -82, -85, -84,  -3, -73, -70, -70, -81, -81, -69, -80, -70, -70,  39, -96, -83; D=-24;
/I:         I=-24; MD=-48;
/M: SY='C';  M= -77,  98, -78, -68, -91, -88, -81, -94,  74, -90, -82, -70, -87, -67, -54, -75, -74, -86, -97, -86; D=-24;
/I:         I=-24; MD=-48;
/M: SY='H';  M= -75, -91, -69, -69, -85, -79, 119, -98, -73, -86, -73, -58, -83, -63, -70,  41, -71, -94,-112, -58; D=-24;
/I:         I=-24; MI=0; MD=-48; IM=0; DM=-48;
/M: SY='S';  M= -58, -81, -72, -75, -91,  23, -76, -92, -74, -94, -87, -60, -80, -67, -79,  84, -55, -84, -96, -83; D=-24;
/I:         I=-24; DM=-48;
/M: SY='N';  M= -65, -79, -63, -73, -88, -69, -70, -85, -69, -90, -82,  63, -80, -67, -76,  55,  48, -80,-103, -83; D=-24;
/I:         I=-24; DM=-48;
/M: SY='A';  M=  64, -72,  51, -57, -84, -58, -69, -78, -65, -80, -74, -56, -72, -61, -71,  48, -54, -67, -89, -76; D=-24;
/I:         I=-24; DM=-48;
/M: SY='P';  M= -64, -74, -79, -70,  55, -79, -72, -40, -72,  40, -45, -78,  76, -74, -76, -70, -59,  43, -68, -51;
/M: SY='P';  M=  46, -73, -68, -59, -68,  29, -66, -60, -63,  31, -53, -64,  59,  48, -67, -54, -60, -59, -74, -68;
/M: SY='Q';  M=  49, -71, -54, -46, -81, -56, -53, -72, -49, -72, -62,  44, -67,  95, -51,  29, -52, -67, -77, -66;
/M: SY='P';  M= -55, -73, -59, -53, -76, -64, -64, -70,  49, -75, -66, -53,  76, -54, -53,  43,  62, -66, -80, -70;
/M: SY='S';  M=  70, -62, -61, -58, -75, -49, -64, -69, -60, -72, -66, -52, -65, -53, -64,  80, -43, -58, -79, -69;
/M: SY='Q';  M= -61, -82, -54,  52, -77, -71, -55, -65, -50, -62,  77, -61,  73,  80, -55, -58, -60, -68, -76, -66;
/M: SY='C';  M= -62, 124, -75, -66, -62, -77, -68, -58, -67,  42, -51, -67, -83,  62, -69, -64, -62, -58, -84, -67;
/M: SY='P';  M= -60, -77,  65, -51, -69, -66, -62, -62, -62,  31, -59, -55,  76, -60, -69,  42, -54, -65, -83, -68;
/M: SY='H';  M= -67, -75, -66, -65,  71, -77, 119, -53, -66, -52, -50, -56, -76, -62, -62, -64, -64,  36, -72, -34;
/M: SY='V';  M=  39, -68, -80, -74, -56, -74, -81,  57, -73, -42, -44, -74, -74, -72, -76, -60, -53,  75, -81, -62;
/M: SY='C';  M= -63,  84, -66, -53, -64, -75, -61, -58,  49,  42, -49, -60, -74,  77, -49, -61, -61, -60, -76, -63;
/M: SY='Q';  M= -61, -73, -64, -53, -63, -74, -58, -55, -47,  42, -48, -58, -71,  77,  49, -54,  54, -56, -76, -60;
/M: SY='N';  M= -61, -76, -56, -63, -69,  36, -58,  47, -47, -64, -58,  74, -73, -54,  62, -55, -58, -56, -80, -66;
/M: SY='E';  M= -64, -83, -46,  83, -53, -75, -50, -72, -51, -69, -64, -64,  60, -46, -58, -61, -62, -72, -57,  83;
/M: SY='H';  M=  33, -76, -59, -54, -78,  50,  97, -80, -56, -73, -61, -50, -68,  70, -57, -50, -63, -75, -81, -57;
/I:         I=-45; MI=0; MD=-92; IM=0; DM=-92;
/M: SY='R';  M= -57, -77, -57, -45, -79, -65, -54, -78,  58, -75, -64, -50, -67,  64,  67,  48, -54, -73, -75, -64;
/M: SY='M';  M= -58, -70, -74, -69, -56, -78,  86, -32, -68, -41,  91, -65, -74, -63, -66, -65, -56,  74, -87, -51;
/M: SY='L';  M= -67, -71, -85, -78, -42, -87, -71,  45, -78,  83, -29, -82, -82, -72, -76, -77, -62, -34, -71, -54;
/M: SY='S';  M=  50, -64, -64, -61, -64, -55, -64, -58, -63,  32, -54, -56, -68, -56, -66,  77, -45, -54, -78, -64;
/M: SY='P';  M= -67, -89, -66, -54, -83, -71, -64, -76, -47, -81, -68, -67, 113, -57,  65, -63, -61, -78, -78, -76;
/M: SY='H';  M=  32, -77, -61, -53, -73, -68,  94, -79, -37, -71, -60, -53, -72, -45,  90, -56, -63, -72, -82, -55;
/M: SY='P';  M= -59, -84, -53,  58, -84,  52, -65, -81, -57, -83, -72, -61,  92, -55, -68, -57, -62, -80, -78, -79;
/M: SY='P';  M= -56, -72, -56, -60, -72, -61, -61, -54, -59, -68, -62,  70,  76, -59, -67,  42, -48,  42, -86, -71;
/M: SY='D';  M= -63, -75,  64, -55, -61, -75, -67, -44, -67,  42, -49, -62,  59, -66, -72, -65, -58,  43, -84, -65;
/M: SY='Y';  M= -60, -77, -71, -75, -37,  52, -52, -52, -68, -57, -54, -65, -77, -65, -69, -60, -63,  36, -45, 105;
/M: SY='D';  M= -58, -79,  66,  52, -84,  28, -59, -82, -55, -82, -75, -49,  60, -51, -64,  28, -56, -78, -84, -74;
/M: SY='N';  M=  49, -69, -55, -54, -69, -59, -55, -60, -54,  25, -53,  71, -71,  70, -58, -49, -54, -60, -78, -65;
/M: SY='S';  M=  50, -62, -59, -58, -73, -53, -64, -67, -59, -71, -65, -49, -63, -54, -64,  78,  56, -58, -82, -67;
/I:         I=-26; MD=-54;
/M: SY='P';  M= -84,-106, -83, -71,-100, -89, -80, -94, -62, -98, -86, -84,  92, -73,  54, -80, -79, -96, -96, -92; D=-26;
/I:         I=-26; MI=-54; MD=-54; IM=-54; DM=-54;
/M: SY='T';  M=  23, -85, -79, -75, -90, -83, -80, -85, -61, -85, -79, -71, -83, -70,  54, -62,  60, -76, -98, -83; D=-26;
/I:         I=-26; DM=-54;
/M: SY='A';  M=  63, -81, -90, -83, -78, -76, -87, -68, -85,  31, -64, -86, -89, -80, -87, -68, -73, -65, -92, -82; D=-26;
/I:         I=-26; DM=-54;
/M: SY='C';  M= -75,  91, -92, -90, -74, -89, -87, -70, -89,  37, -65, -83, -98, -85, -91,  31, -72, -71,-100, -82; D=-26;
/I:         I=-26; DM=-54;
/M: SY='M';  M= -67, -86, -83, -84, -84,  27, -77, -76, -80, -72,  83, -71, -85, -73, -83,  54, -67, -77, -95, -79; D=-26;
/I:         I=-26; DM=-54;
/M: SY='R';  M= -72, -85, -70, -58, -74, -83, -63, -73,  51,  16, -61, -64, -79, -50,  85, -69, -69, -73, -80, -68; D=-26;
/I:         I=-26; DM=-54;
/M: SY='I';  M=  24, -79, -67,  50, -64, -81, -75,  54, -69,  27, -51, -75, -75, -63, -74, -68, -65, -46, -81, -69; D=-26;
/I:         I=-26; DM=-54;
/M: SY='S';  M= -56,  75, -69, -66, -83, -64, -71, -81, -68, -84, -77, -61,  66, -64, -75,  77, -51, -75, -91, -79; D=-26;
/I:         I=-26; DM=-54;
/M: SY='S';  M=  26, -74, -66, -62, -81, -61, -65, -81, -52, -81, -73, -56, -73, -54,  55,  77, -51, -72, -86, -72; D=-26;
/I:         I=-26; DM=-54;
/M: SY='P';  M= -67, -89, -68, -59, -59, -70, -60, -69, -63, -75, -65, -73, 116, -65, -72, -64, -60, -74, -60,  72;
/M: SY='S';  M= -50, -69, -59, -65, -67,  53, -61, -65, -62,  25, -59,  44, -70, -57, -67,  67, -50, -65, -79, -67;
/M: SY='H';  M=  20, -74, -60, -59, -76,  29,  86, -77, -61, -76, -65, -51,  59, -55, -64,  55, -53, -72, -83, -62;
/M: SY='P';  M= -67, -86,  87, -42, -87, -66, -61, -79, -59, -84, -76, -51, 100, -60, -69, -60, -58, -81, -89, -77;
/M: SY='R';  M= -64, -78, -45,  61, -78, -69, -50, -82, -33, -77, -68,  64, -68, -40,  85, -55, -59, -77, -81, -68;
/M: SY='F';  M=  48, -69, -80, -74,  61, -72, -73,  55, -73,  29, -43, -73, -76, -72, -75, -62, -59, -38, -63, -47;
/M: SY='H';  M=  49, -66, -58, -57, -72, -56,  86, -71, -59, -70, -62, -49, -65, -53, -61,  64,  35, -62, -85, -58;
/M: SY='H';  M= -60, -75, -56, -50, -75,  22,  86, -78,  78, -74, -63, -47, -64, -47, -39, -52,  40, -73, -80, -58;
/M: SY='S';  M= -44, -68, -58, -63, -77,  61, -63, -79, -61, -80, -72, -46, -65, -54, -66,  90, -45, -72, -79, -70;
/M: SY='S';  M=  26, -69, -62, -59, -70,  43, -64, -67,  43,  11, -60, -53, -67, -54, -55,  55, -52, -63, -76, -67;
/M: SY='Y';  M= -68, -76,  51, -59, -43, -78, -54, -50, -59,  57, -44, -63, -79, -60,  34, -67, -63, -55, -60,  73;
/I:         I=-10; MI=0; MD=-20; IM=0; DM=-20;
/M: SY='F';  M= -72, -85, -67,  50,  54, -88, -71,  54, -59, -56, -58, -73, -77, -61,  40, -73, -69, -52, -71, -55; D=-10;
/I:         I=-10; DM=-20;
/M: SY='L';  M= -73, -75, -91, -83, -47, -92, -75, -38, -84,  86, -34, -90, -91, -77, -81, -84, -69, -46, -77, -60; D=-10;
/I:         I=-10; DM=-20;
/M: SY='Q';  M=  45, -88, -64,  51, -97, -77, -72, -89, -63, -86, -79, -72, -78,  63, -68, -63, -73, -81, -91, -84; D=-10;
/I:         I=-10; DM=-20;
/M: SY='N';  M= -78, -86, -57, -65, -93, -72, -63, -92,  56, -97, -83,  89, -84, -61, -56, -64, -66, -92,-100, -85; D=-10;
/I:         I=-10; DM=-20;
/M: SY='D';  M= -81, -96,  90,  46,-102, -83, -68,-101, -66, -97, -96, -55, -79, -63, -75, -71, -73, -96,-111, -87; D=-10;
/I:         I=-10; DM=-20;
/M: SY='Y';  M= -84, -94, -87, -81, -53, -95, -64, -69, -64,  25, -61, -84, -96, -70,  54, -82, -80, -73, -64,  79; D=-10;
/I:         I=-10; DM=-20;
/M: SY='T';  M= -69, -80, -81, -80, -71, -82, -81, -64, -79,  38, -62, -72, -84, -76, -83,  41,  54, -64, -94, -76; D=-10;
/I:         I=-10; DM=-20;
/M: SY='H';  M= -73, -86, -62, -71, -88, -72,  93, -94, -69, -91, -78,  63, -84, -64, -71,  41, -65, -92,-110, -69; D=-10;
/I:         I=-10; DM=-20;
/M: SY='S';  M= -56, -79, -71, -72, -89, -64, -74, -89, -72, -93, -86, -59, -79, -64, -76,  93, -51, -81, -98, -81; D=-10;
/I:         I=-10; DM=-20;
/M: SY='D';  M= -80, -98,  64, -53, -99, -84, -66, -97, -53, -92, -84, -60, -85,  63,  55, -70, -76, -94, -98, -80; D=-10;
/I:         I=-10; DM=-20;
/M: SY='M';  M= -83, -87,-101, -95,  61, -99, -83,  29, -91,  27,  62, -92, -95, -89, -89, -89, -78, -54, -74, -54; D=-10;
/I:         I=-10; DM=-20;
/M: SY='P';  M=  38, -84, -78, -72, -93, -69, -80, -86, -76, -91, -82, -72,  59, -72, -82,  54, -62, -79, -94, -87; D=-10;
/I:         I=-10; DM=-20;
/M: SY='H';  M= -80, -94, -80, -75, -78, -87,  86, -75, -79,  24, -65, -75,  62, -74, -80,  -7, -75, -80, -98, -69; D=-10;
/I:         I=-10; DM=-20;
/M: SY='H';  M= -79, -90, -69, -70, -83, -85, 119, -92, -73, -82, -71, -59, -82, -66, -71, -66,  47, -88,-114, -58; D=-10;
/I:         I=-10; DM=-20;
/M: SY='Q';  M= -72, -91, -64, -65, -98,  36, -66, -95, -64, -94, -81,  63, -84,  76, -68, -62, -73, -95, -94, -84; D=-10;
/I:         I=-10; DM=-20;
/M: SY='T';  M= -63, -77, -72, -74, -85, -76, -80, -78, -72, -83, -78, -61, -76, -72, -79,  48,  83, -70,-101, -81; D=-10;
/I:         I=-10; DM=-20;
/M: SY='C';  M=  45,  84, -69,  50, -92, -79, -81, -90, -72, -86, -82, -77, -83, -69, -80, -67, -72, -78, -98, -90; D=-10;
/I:         I=-10; DM=-20;
/M: SY='H';  M=  32, -88, -76, -78, -91,  49,  86, -96, -79, -89, -78, -66, -83, -73, -80, -65, -78, -88, -97, -74; D=-10;
/I:         I=-10; DM=-20;
/M: SY='D';  M= -75, -91,  65,  51, -90, -88, -75, -70, -69, -80, -80, -66, -81, -66, -77, -74, -71,  35,-106, -84; D=-10;
/I:         I=-10; DM=-20;
/M: SY='H';  M= -75, -91, -69, -69, -85, -79, 119, -98, -73, -86, -73, -58, -83, -63, -70,  41, -71, -94,-112, -58; D=-10;
/I:         I=-10; DM=-20;
/M: SY='P';  M= -84, -99, -88, -78,  60, -88, -84, -79, -83, -80, -78, -90,  95, -88, -91, -82, -77, -84, -78, -66; D=-10;
/I:         I=-10; DM=-20;
/M: SY='T';  M=  17, -81, -73, -68, -88, -79, -80, -81,  48, -84, -77, -65, -77, -68, -62, -58,  69, -73, -95, -82; D=-10;
/I:         I=-10; DM=-20;
/M: SY='P';  M= -78, -98, -88, -79, -84, -90, -91,  26, -83, -74, -70, -90,  91, -85, -92, -81, -72,  22, -95, -87; D=-10;
/I:         I=-10; MI=0; MD=-20; IM=0; DM=-20;
/M: SY='S';  M= -75, -94, -96, -94, -93, -91, -99, -70, -94, -85, -85, -86, -99, -89, -97,  53, -71,  41,-115, -94; D=-10;
/I:         I=-10; DM=-20;
/M: SY='P';  M=  31, -96, -82, -72, -98, -77, -85, -86, -78, -94, -83, -85,  98, -79, -88, -71, -72, -85, -93, -95; D=-10;
/I:         I=-10; DM=-20;
/M: SY='Y';  M= -82, -87, -71, -82, -56, -82, -61, -69, -76,  24, -63,  70, -95, -74, -78, -74, -72, -74, -71,  72; D=-10;
/I:         I=-10; DM=-20;
/M: SY='C';  M= -76,  98, -94, -93, -60, -95, -80, -60, -88, -68, -68, -87,-100, -90, -89, -80, -74,  42, -79,  65; D=-10;
/I:         I=-10; DM=-20;
/M: SY='F';  M= -76, -90, -85, -80,  67, -82, -81, -78, -82, -76, -77, -79,  65, -82, -86,  40, -69, -80, -76, -59; D=-10;
/I:         I=-10; DM=-20;
/M: SY='L';  M= -74, -87, -91, -92, -68,  48, -85, -62, -90,  56, -56, -83, -92, -85, -91, -79, -80, -67, -87, -76; D=-10;
/I:         I=-10; DM=-20;
/M: SY='H';  M= -69, -84, -62, -71, -88, -70,  80, -93, -69, -92, -80,  63, -84, -64, -72,  54, -62, -90,-107, -72; D=-10;
/I:         I=-10; DM=-20;
/M: SY='H';  M= -84, -99, -77, -75, -63, -87,  93, -86, -77, -81, -71, -74,  58, -71, -76, -78, -80, -90, -74,  72; D=-10;
/I:         I=-10; DM=-20;
/M: SY='H';  M= -83, -98, -75, -67, -88, -90,  86, -99, -47, -88, -75, -67, -89, -57,  85, -76, -82, -94, -98, -67; D=-10;
/I:         I=-10; DM=-20;
/M: SY='Q';  M= -77, -99, -69, -54, -96, -84,  86, -94, -60, -85, -71, -62, -83,  99, -59, -67, -79, -95, -95, -66; D=-10;
/I:         I=-10; DM=-20;
/M: SY='Y';  M= -79, -91, -89, -90, -43, -95, -63, -55, -83, -63, -62, -89, -97, -81, -82, -81, -75,  42, -55, 102; D=-10;
/I:         I=-10; DM=-20;
/M: SY='L';  M= -85, -85,-101, -94,  58,-100, -83, -52, -94,  62, -49, -97,-100, -91, -90, -92, -80, -59, -74, -55; D=-10;
/I:         I=-10; DM=-20;
/M: SY='D';  M= -64, -85,  65,  45, -90, -70, -65, -88, -60, -88, -83, -54,  44, -56, -69,  48, -58, -83, -95, -79; D=-10;
/I:         I=-10; DM=-20;
/M: SY='K';  M= -64, -79, -57, -44, -78, -72, -56, -80,  95, -77, -65, -50, -66, -40,  68, -58, -60, -75, -73, -64;
/M: SY='H';  M= -69, -81, -53, -53, -68, -71, 149, -86, -58, -68, -54, -43, -70, -47, -52, -59, -68, -86,-103, -37;
/M: SY='P';  M=  68, -72, -67, -62, -80,  43, -70, -73, -64, -76, -67, -62,  76, -63, -72, -49, -57, -65, -76, -76;
/M: SY='Y';  M=  34, -68, -63, -65, -51,  23, -56, -65, -62, -65, -60, -55, -68, -59, -66,  35,  55, -60, -58,  80;
/M: SY='C';  M= -62,  91, -67, -65, -56, -72, -62, -66, -64, -67, -62, -63,  76, -67, -71, -54,  61, -63, -67,  66;
/M: SY='Q';  M=  26, -69, -67, -57, -62, -65, -62, -48, -59,  39, -47, -61, -72,  70, -61,  42, -53,  24, -76, -61;
/M: SY='T';  M=  49, -63, -65, -63, -62, -64, -68, -53, -62,  26, -52, -56, -65, -63, -68, -43,  87, -48, -80, -64;
/M: SY='T';  M=  21, -66, -60, -63, -74,  50, -67, -70, -61, -72, -66, -49, -63, -59, -68,  50,  72, -61, -81, -69;
/I:         I=-31; MI=0; MD=-64; IM=0; DM=-64;
/M: SY='Y';  M= -60, -76, -61, -63, -39, -66,  87, -67, -61, -63, -56, -55, -73, -53, -59,  58, -55, -68, -49, 103;
/M: SY='A';  M=  78, -68, -67, -62, -79,  44, -70, -71, -64, -73, -65, -61,  51, -62, -71, -46, -56, -61, -76, -75;
/I:         I=-13; MD=-25;
/M: SY='L';  M= -77, -81, -89, -86, -63, -95, -83, -54, -85,  60, -51, -83, -89, -83, -87, -74,  53, -58, -91, -72; D=-13;
/I:         I=-13; MI=-25; MD=-25; IM=-25; DM=-25;
/M: SY='E';  M= -75, -96, -46,  97, -99, -91, -69,-100, -56, -92, -88, -72, -70, -49, -67, -72, -76, -92, -95, -89; D=-13;
/I:         I=-13; DM=-25;
/M: SY='H';  M= -85, -96, -68, -69, -83, -86, 133,-101, -73, -84, -69, -58, -85, -62, -67, -74, -83,-101,-119, -52; D=-13;
/I:         I=-13; DM=-25;
/M: SY='Y';  M= -84, -88, -95, -91, -47, -98, -70, -54, -89,  60, -49, -95, -99, -82, -86, -89, -79, -61, -66,  72; D=-13;
/I:         I=-13; DM=-25;
/M: SY='Y';  M= -78, -95, -84, -90, -47,  41, -60, -80, -82, -77, -72, -79, -93, -78, -82, -75, -82, -83, -53, 102; D=-13;
/I:         I=-13; DM=-25;
/M: SY='Y';  M= -82, -97,  65,  44, -67, -87, -62, -89, -69, -85, -82, -66, -83, -64, -75, -74, -76, -88, -74,  72; D=-13;
/I:         I=-13; DM=-25;
/M: SY='S';  M=  33, -82, -77, -78, -93,  42, -81, -91, -78, -92, -84, -66, -81, -72, -83,  54, -64, -81, -93, -86; D=-13;
/I:         I=-13; DM=-25;
/M: SY='E';  M= -70, -90,  52,  58, -97, -78, -70, -96, -65, -94, -90, -61, -76, -59, -73,  47, -65, -90,-102, -85; D=-13;
/I:         I=-13; DM=-25;
/M: SY='T';  M= -70, -82, -62,  50, -87, -86, -78, -81, -66, -82, -79, -65, -73, -66, -76, -57,  83, -73,-101, -83; D=-13;
/I:         I=-13; DM=-25;
/M: SY='F';  M= -81, -92, -75,  49,  54, -99, -83,  54, -78, -60, -64, -84, -85, -74, -83, -83, -77, -56, -78, -61; D=-13;
/I:         I=-13; DM=-25;
/M: SY='R';  M= -77, -92, -84, -73, -83, -95, -76, -66, -50, -75, -71, -78, -92, -64,  84, -78, -75,  41, -95, -77; D=-13;
/I:         I=-13; DM=-25;
/M: SY='N';  M= -73, -85, -57, -77, -94,  36, -64, -95, -68,-100, -87,  96, -87, -69, -76, -61, -67, -95,-104, -89; D=-13;
/I:         I=-13; DM=-25;
/M: SY='Y';  M=  37, -89, -85, -84, -46, -81, -60, -74, -80, -73, -68, -84, -92, -75, -79, -71, -76, -73, -53, 102; D=-13;
/I:         I=-13; DM=-25;
/M: SY='S';  M= -65, -81, -79, -79,  60, -73, -77, -79, -78, -77, -78, -68, -85, -73, -81,  76, -59, -77, -79, -59; D=-13;
/I:         I=-13; DM=-25;
/M: SY='L';  M= -77, -83, -99, -92, -60,-101, -88, -42, -92,  60, -48, -97, -98, -88, -91, -89, -74,  43, -91, -71; D=-13;
/I:         I=-13; DM=-25;
/M: SY='Y';  M= -70, -94, -81, -90, -66,  71, -72, -92, -83, -88, -80, -71, -88, -80, -87, -69, -82, -91, -67,  72; D=-13;
/I:         I=-13; DM=-25;
/M: SY='C';  M= -77, 121, -86, -79, -89, -90, -87, -94,  48, -87, -83, -75, -95, -79, -69, -77, -75, -84,-105, -91; D=-13;
/I:         I=-13; DM=-25;
/M: SY='N';  M= -70, -81, -55, -72, -91, -65, -62, -91, -65, -97, -85,  96, -86, -65, -73,  42, -58, -90,-107, -85; D=-13;
/I:         I=-13; DM=-25;
/M: SY='G';  M= -67, -94, -76, -72,-100,  71, -77,-100, -72, -96, -84, -65, -83,  69, -76, -64, -81, -97, -88, -87; D=-13;
/I:         I=-13; DM=-25;
/M: SY='S';  M= -63, -85, -73, -70, -90, -72, -72, -92, -58, -92, -84, -63, -82, -61,  55,  76, -58, -84, -95, -80; D=-13;
/I:         I=-13; DM=-25;
/M: SY='H';  M= -72, -92, -69, -62, -91, -78,  93, -94, -66, -87, -74, -60, -82,  69, -65,  41, -70, -92,-100, -66; D=-13;
/I:         I=-13; DM=-25;
/M: SY='H';  M= -75, -86, -80, -79,  67, -81,  79, -80, -80, -72, -72, -69, -88, -75, -78,  47, -69, -80, -79, -50; D=-13;
/I:         I=-13; DM=-25;
/M: SY='Y';  M= -73, -90,  64, -63, -68, -77, -65, -87, -73, -87, -83, -61, -85, -69, -78,  47, -66, -86, -78,  65; D=-13;
/I:         I=-13; DM=-25;
/M: SY='V';  M= -71, -85,  50, -74, -76, -93, -89, -45, -83, -63, -66, -77, -90, -85, -87, -78, -67,  74,-107, -79; D=-13;
/I:         I=-13; DM=-25;
/M: SY='M';  M= -65, -79, -78, -77, -79, -78, -76, -70, -75, -68,  77, -66, -79, -71, -79,  48,  61, -68, -97, -76; D=-13;
/I:         I=-13; DM=-25;
/M: SY='S';  M= -59, -78, -71, -73, -87, -69, -76, -84, -72, -88, -83, -60, -77, -67, -78,  80,  48, -76, -99, -81; D=-13;
/I:         I=-13; DM=-25;
/M: SY='H';  M= -78, -93, -74, -71, -88, -84,  93, -88, -75, -86, -76, -67,  65, -72, -78, -67,  47, -86,-105, -71; D=-13;
/I:         I=-13; DM=-25;
/M: SY='H';  M= -80, -91, -68,  50, -74, -93,  79, -72, -73,  37, -61, -75, -84, -64, -75, -80, -79, -75, -97, -68; D=-13;
/I:         I=-13; DM=-25;
/M: SY='R';  M= -77, -86, -81, -75, -76, -91, -76, -71, -59,  24, -65, -74, -87, -69,  62, -69,  53, -70, -93, -76; D=-13;
/I:         I=-13; DM=-25;
/M: SY='M';  M= -81, -92, -81, -75, -77, -90,  86, -74, -63, -64,  91, -71, -87, -64,  48, -79, -79, -77, -97, -63; D=-13;
/I:         I=-13; DM=-25;
/M: SY='Q';  M= -64, -85, -60, -45, -83, -70, -56, -77,  45, -77, -64, -57,  76,  77,  57, -57, -61, -77, -75, -68;
/M: SY='P';  M=  33, -77, -55,  51, -82,  53, -66, -79, -58, -79, -70, -59,  73, -55, -67, -52, -60, -73, -77, -77;
/M: SY='D';  M=  49, -69,  65,  46, -78, -62, -61, -72, -54, -72, -68, -49, -62, -52, -62, -46,  55, -63, -86, -70;
/M: SY='P';  M= -58, -82, -61, -50, -84, -63, -62, -74, -56, -80, -68, -60, 104,  63, -63,  48, -53, -75, -78, -74;
/M: SY='A';  M=  68, -66, -73, -64, -63, -64, -69, -45, -59,  19, -50, -68, -73, -61,  34, -53, -55,  44, -77, -64;
/M: SY='P';  M= -64, -90, -63, -48, -87, -68, -62, -74, -55, -80, -66, -65, 114,  76, -62, -59, -60, -79, -77, -76;
/M: SY='H';  M= -59, -79, -58, -63, -74,  72, 121, -88, -63, -76, -63, -46, -69, -55, -62, -54, -68, -85, -87, -51;
/M: SY='H';  M= -70, -82, -61, -63, -35, -74, 117, -68, -62, -60, -51, -56, -76, -54, -57, -62, -67, -71, -48, 108;
/M: SY='K';  M= -64, -75, -68, -57, -57, -78, -66,  48,  78,  42, -44, -62, -71, -54, -44, -66, -59, -45, -72, -59;
/M: SY='G';  M= -49, -77, -64, -76, -83, 103, -71, -91, -70, -86, -75, -50, -68, -67, -77, -49, -68, -84, -74, -78;
/M: SY='T';  M=  49, -61, -60, -60, -70, -62, -68, -60, -59, -64, -60, -51, -61, -61, -66, -37, 100, -51, -84, -67;
/M: SY='S';  M= -41, -64, -56, -57, -74, -49, -59, -74, -57, -77, -71, -44, -64, -48, -61, 109, -35, -66, -82, -66;
/M: SY='V';  M= -52, -66, -83, -77, -54, -84, -86, -19, -75, -39, -42, -78, -79, -77, -76, -66, -50, 103, -88, -62;
/M: SY='I';  M= -65, -78, -86, -85, -49, -91, -86, 108, -79, -32, -35, -76, -74, -76, -83, -74, -58, -19, -73, -56;
/M: SY='I';  M= -65, -78, -86, -85, -49, -91, -86, 108, -79, -32, -35, -76, -74, -76, -83, -74, -58, -19, -73, -56;
/M: SY='T';  M= -52, -61, -57, -61, -67, -68, -68, -58, -57, -63, -60, -47, -59, -62, -66, -35, 115, -50, -88, -65;
/M: SY='N';  M= -62, -67, -35, -57, -77, -50, -43, -76, -48, -84, -70, 125, -73, -50, -56, -44, -47, -78, -96, -72;
/M: SY='G';  M= -51, -78, -54,  50, -83,  92, -66, -89, -61, -84, -75, -52, -65, -57, -70, -51, -66, -82, -75, -77;
/M: SY='R';  M= -53, -73, -60, -54, -75, -62, -55, -78, -36, -76, -67, -50, -69, -44,  90,  77, -49, -71, -79, -64;
/I:         E1=0; IE=-305; DE=-305;

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Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2024_02 which contains 571'282 sequence entries.

Total number of hits	7 in 7 different sequences
Number of true positive hits	7 in 7 different sequences
Number of 'unknown' hits	0
Number of false positive hits	0
Number of false negative sequences	0
Number of 'partial' sequences	0

Precision (true positives / (true positives + false positives))	100.00 %
Recall (true positives / (true positives + false negatives))	100.00 %

Comments [info]

Matrix type [info]	protein_domain
Scaling database [info]	reversed
Author [info]	CJA_Sigrist
Taxonomic range [info]	Eukaryotes
Maximum number of repetitions [info]	1
Feature key [info]	DOMAIN
Feature description [info]	Single-minded C-terminal
Version [info]	3

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences

7 sequences

SIM1A_DANRE (Q98SJ5), SIM1_HUMAN  (P81133), SIM1_MOUSE  (Q61045),

SIM1_PANPA  (A1YFY6), SIM1_PANTR  (A2T6X9), SIM2_HUMAN  (Q14190), 
SIM2_MOUSE  (Q61079)

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Retrieve an alignment of UniProtKB/Swiss-Prot true positive hits:
[Clustal format, color, condensed view] [Clustal format, color]
[Clustal format, plain text] [Fasta format]
Retrieve the sequence logo from the alignment