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Entry: PS51309

General information about the entry

Entry name [info] PABC
Accession [info] PS51309
Entry type [info] MATRIX
Date [info] 01-APR-2007 CREATED; 01-OCT-2013 DATA UPDATE; 22-NOV-2017 INFO UPDATE.
PROSITE Doc. [info] PDOC51309
Associated ProRule [info] PRU00641

Name and characterization of the entry

Description [info] Poly(A)-binding protein C-terminal (PABC) domain profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=80;
/DISJOINT: DEFINITION=PROTECT; N1=1; N2=80;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=2.2303166; R2=0.0056120; TEXT='NScore';
/CUT_OFF: LEVEL=0; SCORE=1118; N_SCORE=8.5; MODE=1; TEXT='R';
/CUT_OFF: LEVEL=-1; SCORE=619; N_SCORE=5.7; MODE=1; TEXT='R?';
/DEFAULT: M0=-17; D=-100; I=-100; B1=-1000; E1=-1000; MI=-255; MD=-255; IM=-255; DM=-255;
...
                A   C   D   E   F   G   H   I   K   L   M   N   P   Q   R   S   T   V   W   Y
/I:         B1=0; BI=-255; BD=-255;
/M: SY='Q'; M=-11,-48, 10, -4, -7,-15,-29, -5,-26, -1,  7,-29, 22, 60, -2, -5,  3,-11,-42, 13;
/M: SY='T'; M=  1,-43,-10, -4, -2, 17,-37, 13,-35, -3, 10, -5, -4, -3,-40,-26, 32, 16,-44, 11;
/M: SY='D'; M=-32,-48, 37,-20,-46, -5,-30, -9, 34,-11,-34, 11, 29, 27,  8,  7,  1,-38,-52,-38;
/M: SY='N'; M= 14,-43, -2, 26,-14,-35,-30,  8, -7,-22,-32, 32,  8,-24, -6, 24,  0,-13,-46,  9;
/M: SY='Q'; M=  7,-44, -7,-26,  9,-13,-30,-12,  0, -2,-29, 27,  2, 45,  6, 19,  2,-33,-46,-32;
/M: SY='M'; M= 33,-39,-41,-39,  0,-36,-37, 25,-37,  0, 51, 11,  1,-34,-41, 15,  0,  7,-47,-31;
/M: SY='E'; M= -3,-45,-18, 50, -6, -5,-29,-19,-24,-44,-39, 36, 22,  6,-31, 35, -4,-39,-51,-38;
/M: SY='D'; M= -4,-47, 65, 19,-43,-39,-29,-13,-26,-21,  0,-21,-39, 41,-32, -7,  8,  4,-54, -3;
/M: SY='F'; M= -9,-42,-11,-38, 52,-47,-36, -2,-37, 46,-14, -6,-50, 15,-10,-10, -9,-21,-36,-17;
/M: SY='A'; M= 44,-40, 25, -3,-40,-33,-34,-29,  4, 16,-27,  0,-41, 19,-31,  9,-26, -5,-51,-37;
/M: SY='K'; M= 19,-42,  6,-21,-48,-31,-28,-43, 40,-44,  4, 38, -2, 22,  7, 25,  8,-39,-52,-39;
/M: SY='A'; M= 29,-43, -2, 18, -3,-41,-35,  2, 19, 25, 28,-34,-41, 18,-28,-30,-30,-12,-45,-31;
/M: SY='P'; M=-30,-47,-30,-27,-44,-36, 17,-41, -9,-46,-37, 15, 78,  5,-35, 19, 47,-39,-51,  0;
/M: SY='P'; M=-15,-50, 20, 21,-45,-42,-36,-12,-29, -6,-31,-32, 72, 31,-36,-28, 19, -1,-53,-41;
/M: SY='E'; M=-31,-52, 53, 53,-51,-15,-25,-52,  0,-49,-42,-20,  0, 53,-24, 12,-29,-49,-50, -2;
/M: SY='Q'; M=  6,-46, 25, 41,-50,-34,-26,-41, -2,-42,  5, 28,-36, 57,-24, 21,-25,-15,-53,-39;
/M: SY='Q'; M= -7,-51,-27,  3,  7,-39, 52,-46, 17,-40,-30,-23,-39, 91, -2, -6,-32,-45,-44,-26;
/M: SY='R'; M=-37,-49, 10,-20,-41,-46,-28,-39, 60,  3, 27,-26,-42,-16, 62,-33,-33,-38,-47,-34;
/M: SY='Q'; M=-14,-50,  2,  8,-52,-14,-22,-46,-13,-42, 14, 26,-39, 82, 35, -2,-13,-44,-49,-35;
/M: SY='I'; M= 19,-43,-48,-39, 15,-46,-39, 40,-39, 23, 37,-42,-46, 31,-40,-34,-30, 20,-41,  2;
/M: SY='L'; M=-37,-42,-57,-50,-15,-59,-45, 44,-50, 65, -3,-53,-53,-44,-49,-47,-32, 20,-45,-27;
/M: SY='G'; M= -8,-48,-35,-39,-55, 85,-39,-59,  2,-55,-44,-22,-39, 16,-38,-21,-38,-53,-45,-47;
/M: SY='E'; M=-33,-51, 20, 74,-55,-40,-22,-53,  7,-49,-41, 37,-33, 52,-20,-25,-30,-49,-53,-42;
/M: SY='R'; M=-15,-46,-38,-10,-28,-46,-30, -4,  1, 23, 42,-12,  6,  4, 43,-31, 16,-26,-42, 20;
/M: SY='L'; M=-36,-40,-52,-46,-15,-55,-40,  8,-47, 73, -3,-49,-52,-41,-46,-18,  6,-12,-44,-26;
/M: SY='Y'; M=-43,-50,-45,-43, 62,-50, 17,-27,  1,-21, 20,-41,-53,-36,-32,-39,-37,-31, -8, 97;
/M: SY='P'; M=-34,-53,-31,  0, -2,-38,-30,-17, -8,-43,-36, 17, 85, 13,-35, 12,-28,-41,-39, 34;
/M: SY='K'; M=-37,-48,-37,-26,-27,-48,-29, -1, 62, 23, 16,-31,-43,-21, 34,-36,-32,-29,-37, 33;
/M: SY='V'; M=-29,-43,-56,-52,-24,-59,-58, 64,-48, -8,-11,-49,-49,-48,-51,-41,-25, 70,-53,-31;
/M: SY='Q'; M=-31,-48,-24, 45, 15, -9, 36,-36,  8, -7,-30,-28,-39, 48,  4,  7,-31, -5,-46,-28;
/M: SY='E'; M= 29,-46, 31, 35,-52,-35,-29,-46, 14,-45,-38,-24, -4, 35, 27,  9,-27,-25,-51,-40;
/M: SY='H'; M=-33,-45,-35, -6,-31,-46, 40, -2, 28, 29, 27, -4,-43, 11, 19, -5, -8, -1,-49,-29;
/I:         I=-9; MD=-23;
/M: SY='L'; M=-60,-71,-16,-63,-56,-33,-69,-40,-26, 14,-44,-65,  1,-65,-66,-62,-20,  4,-78,-62; D=-9;
/I:         I=-9; MI=0; MD=-23; IM=0; DM=-23;
/M: SY='Q'; M=-59,-76,  5,-12,-80,-25, 17,-80, 12,-77,-66,  9,-65, 18,-45,-21,-55,-77,-82,-63; D=-9;
/I:         I=-9; DM=-23;
/M: SY='N'; M=-16,-46, 40, 38, 25,-39, 29,-40,-24,-39,-35, 40,-39, 26,-30,-25,  7,-19,-46, 12;
/M: SY='P'; M=  5,-52,-28, 25,-50,-39,-35, -3, 36,-45,-36, -4, 76,  8,-25,-11,-28,-38,-49,-44;
/M: SY='Q'; M=  9,-48, 36, 41,-54, -8,-29,-48, 15,-47,-40,-22,  9, 49,-24,  5,  9,-43,-52,-41;
/M: SY='H'; M= -2,-43,-38,-36, 39,-43, 59,-24,-13, 26,-19,  7,-47,  3,-34, -1,  2, -6,-38, 24;
/M: SY='A'; M= 73,-35,-40,-34,-42,-25,-43,-33,-35,-37,-33,-34,-38,-32,-40, -4, 22, -6, 59,-37;
/M: SY='P'; M= 17,-46,-32,-32,  9, 36, 21,-46, 20,-45,-37, 20, 46,-30,-31,  5,-29,-42,-43,  0;
/M: SY='K'; M=-35,-50,-27,-14,-50,-42, 46,-52, 84,-48,-35,-20,-36, 24, 24,-28,-31,-48,-47,-32;
/M: SY='I'; M=-35,-47,-57,-54,-20,-61,-55, 82,-50, 18, -7,-49,-48,-47,-53,-45,-29, 34,-47,-29;
/M: SY='T'; M=  3,-34,-32,-34,-38,-38,-41,-25,-31,-33,-30,-22,-33,-34,-38, 13, 88, 14,-59,-37;
/M: SY='G'; M=-23,-49,-27, 22,-54, 84,-38,-61,-35,-56,-46,  9,-38,-31,-43,-22,-37,-54,-47,-49;
/M: SY='M'; M=-34,-42,-56,-46,-22,-49,-29, 27,-40, 11,120,-43,-43,-32,-38,-43,-32,-10,-46,-22;
/M: SY='L'; M=-38,-42,-57,-49,  6,-57,-41, 33,-49, 67, 43,-53,-53,-42,-47,-48,-34, -8,-42,-23;
/M: SY='L'; M=-35,-41,-51,-46,-17,-53,-42, 31,-46, 66, -5,-46,-50,-40,-46, -2,  7, -9,-45,-27;
/M: SY='E'; M=-34,-53, 69, 72,-57, -9,-25,-57,-19,-51,-48,-18,-32, 18,-28,-27,-32,-51,-58,-44;
/M: SY='M'; M=-37,-46,-46,-38,  7,-49, 23, 10,  0, 34, 70,-41, 48,-34,-37,-39, -5,-20,-45,-26;
/M: SY='D'; M=-30,-48, 70, 26,-54,-14,-29,-51,-26,-52,-47,  5, 42,-24,-35, 30, 10,-47,-61,-43;
/I:         I=-26; MI=0; MD=-65; IM=0; DM=-65;
/M: SY='N'; M=-34,-47,-21, -2,-47,-34,-26,  5,  8,-43,-34, 69, 45, 37, -6,-22, 16,-37,-55,-41;
/I:         I=-26; MI=0; MD=-65; IM=0; DM=-65;
/M: SY='E'; M= 16,-45, 27, 37,-51, -1,-32,-48,  8,-48,-41,-22, 27,  6,-29, 35,  6,-41,-53,-42;
/M: SY='E'; M=-33,-53, 50, 82,-57,-44,-25,-56,  3,-49,-45,-22,-31, 28,-23,-27,-32,-50,-55,-43;
/M: SY='I'; M=-15,-45,-56,-52,-21,-58,-54, 72,-49, 25, -8,-49,-48,-46,-51,-43,-29, 42,-48,-29;
/M: SY='L'; M=-38,-43,-57,-51, 33,-59,-45, 46,-50, 58, -5,-52,-53,-46,-49,-47,-33, 15,-39,-20;
/M: SY='H'; M= -1,-45, 23, 44,-44,-35, 59,-43,-25,-10,  4, 34,  0,-19,-30, 25,-26,-41,-58,-34;
/M: SY='M'; M=-35,-42,-54,-47, 10,-53,-39, 16,-44, 46, 76,-47,-48,-39,-44,-42,  6, 13, 51,-21;
/M: SY='L'; M=-37,-41,-57,-50, 46,-57,-44, 20,-50, 59, -6,-53,-55,-47,-48,-46,-33, 26,-37,-17;
/M: SY='E'; M= -1,-46, 34, 57,-46,-38,-29,-44, 28,-44,-40,-22,-33,-16,-23, 22,  9,-15,-50, -4;
/M: SY='D'; M=-26,-42, 60, 11,-51,-28,-24,-49,-24,-52,-45, 56,-38,-21,-32, 51,  3,-45,-63,-41;
/M: SY='E'; M= -9,-52, 45, 55,-52,-41, 29,-45,  0,-47,-41,-25, 54,-20,-30,-11,-29,-11,-57,-41;
/M: SY='E'; M=-33,-49, 43, 56,-16,-39,-25,-51, 36,-48,-42, 25,-35, 34,-18,  1,-28,-48,-52,-38;
/M: SY='E'; M= 13,-43, 18, 42,-38,-14,-32,-31,-27, 20,  7,-28,-37, 19,-33, -6, 31,-30,-51,-37;
/M: SY='L'; M=-40,-42,-57,-50, 48,-57,-40, 15,-50, 66, 20,-53,-55,-45,-47,-48,-35,-12,-35,-16;
/M: SY='N'; M=-14,-46, -2, -2,-45,-37, 13,-11, 23,-24,-31, 54,-42, 44, 33, -8,-27, -3,-53,-36;
/M: SY='E'; M= 16,-44, 37, 46,-50,-35,-30,-42,  3,-44,-39,-21,-34, 26,-27, 22, 25,-17,-55,-40;
/M: SY='R'; M=-37,-51,-31,-23,-29,-44, 36,-44, 53,-39, 12,  8,-43,  9, 55,-31,-33,-43,-34, 52;
/M: SY='I'; M=-31, 20,-56,-52,  2,-58,-52, 62,-48,  4,-12,-49,-50,-48,-50,-42,-28, 59,-46,  5;
/M: SY='D'; M= -5,-47, 51, 25,-54, -4,-24,-50, 12,-50,-41, 46,-37, 48,-24, -2, -6,-47,-56,-41;
/M: SY='E'; M=-33,-52, 46, 84,-55,-44,-25,-54,-16,-49,-45,-23,-30, 20,-25,-26,  0,-48,-55,-43;
/M: SY='A'; M= 76, 14,-39,-35,-48, 28,-42,-41,-36,-42,-35,-32,-39,-33,-41,-15,-26,-28,-48,-45;
/M: SY='M'; M=-32,-42,-50,-47,  2,-50,-41, 48,-44, 36, 54,-12,-48,-39,-45,  7,-27, 25,-46,-26;
/M: SY='E'; M=  6, 12, 35, 66,-53,-22,-28,-50,  8,-47,-42,  8,-33, 19,-25,-23,  9,-43,-55,-43;
/M: SY='V'; M= 22,-40,-50,-41,-25,-47,-44, 10,-42, 42,-11,-46,-49, 14,-42,-34,-28, 50,-49,-31;
/M: SY='I'; M=-39,-46,-55,-51,  8,-58,-39, 57,-48, 52, -6,-51,-52,-43,-47,-46,-34, -5,-33, 43;
/M: SY='Q'; M=-12,-49,-27, 21,-44,-42,-28,  2, 37, -9,-29, 16,-39, 48, 43,-27, -4,-34,-48,-35;
/M: SY='E'; M= -2,-47,-18, 64, -5, -8, 17,-43,  9,-24,-36,-27,-34,  6, -4, 23,-28,-19,-48,-35;
/M: SY='H'; M= -2,-45,-26, 14,  9,-35, 63,-39, -4,-38,-33, 38,-41,  7,-28, 25,-27, -9, 51, 24;
/M: SY='Q'; M= 21,-43,-34,-23, -4,-14,-32,-13, 33,  0,-27,-27,-39, 58,-21,  6, 13,-17,-45,-32;
/M: SY='Q'; M=  2, 37,-10,  5,-48, -1,-31,-44, 39,-22,-35,  3, -4, 42,  0, 11,  9,-40,-50,-39;
/I:         E1=0; IE=-255; DE=-255;
» more

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2017_11 which contains 556'196 sequence entries.


Total number of hits 53 in 53 different sequences
Number of true positive hits 53 in 53 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 0
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 100.00 %

Comments [info]

Matrix type [info] protein_domain
Scaling database [info] reversed
Author [info] CJA_Sigrist
Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 1
Feature key [info] DOMAIN
Feature description [info] PABC
Version [info] 4

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
53 sequences

EPABA_XENLA (Q98SP8    ), EPABB_XENLA (Q6GR16    ), EPAB_XENTR  (Q6DEY7    ), 
HYD_DROME   (P51592    ), MPC_ARATH   (Q9LT82    ), PABP1_BOVIN (P61286    ), 
PABP1_HUMAN (P11940    ), PABP1_MOUSE (P29341    ), PABP1_PONAB (Q5R8F7    ), 
PABP1_RAT   (Q9EPH8    ), PABP2_ARATH (P42731    ), PABP3_ARATH (O64380    ), 
PABP3_HUMAN (Q9H361    ), PABP4_ARATH (O22173    ), PABP4_HUMAN (Q13310    ), 
PABP5_ARATH (Q05196    ), PABP7_ARATH (Q9ZQA8    ), PABP8_ARATH (Q9FXA2    ), 
PABPA_XENLA (P20965    ), PABPB_XENLA (Q6IP09    ), PABP_ASHGO  (Q74ZS6    ), 
PABP_ASPCL  (A1CRM1    ), PABP_ASPFU  (Q4WK03    ), PABP_ASPNC  (A2Q848    ), 
PABP_ASPOR  (Q2UK72    ), PABP_ASPTN  (Q0CR95    ), PABP_CANAL  (Q5AI15    ), 
PABP_CANGA  (Q6FKG4    ), PABP_CHAGB  (Q2GSX8    ), PABP_COCIM  (Q1DXH0    ), 
PABP_CRYNB  (P0CP47    ), PABP_CRYNJ  (P0CP46    ), PABP_DEBHA  (Q6BI95    ), 
PABP_DROME  (P21187    ), PABP_EMENI  (Q5B630    ), PABP_KLULA  (Q6CSV3    ), 
PABP_LODEL  (A5DW14    ), PABP_MAGO7  (A4QUF0    ), PABP_NEOFI  (A1D4K4    ), 
PABP_NEUCR  (Q7S6N6    ), PABP_PHANO  (Q0U1G2    ), PABP_PICGU  (A5DM21    ), 
PABP_PICST  (A3LXL0    ), PABP_SCHPO  (P31209    ), PABP_USTMA  (Q4P8R9    ), 
PABP_YARLI  (Q6CDH3    ), PABP_YEAST  (P04147    ), PAP1A_DICDI (Q54BM2    ), 
PAP1B_DICDI (Q1ZXC2    ), PAP1L_HUMAN (Q4VXU2    ), UBR5_HUMAN  (O95071    ), 
UBR5_MOUSE  (Q80TP3    ), UBR5_RAT    (Q62671    )
» more

PDB
[Detailed view]
19 PDB

1G9L; 1I2T; 1IFW; 1JGN; 1JH4; 2RQG; 2RQH; 2X04; 3KTP; 3KTR; 3KUI; 3KUJ; 3KUR; 3KUS; 3KUT; 3NTW; 3PKN; 3PTH; 4IVE
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View entry in raw text format (no links)
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