PROSITE entry PS51320

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General information about the entry

Entry name [info]	TIFY
Accession [info]	PS51320
Entry type [info]	MATRIX
Date [info]	01-JUN-2007 CREATED; 10-MAY-2017 DATA UPDATE; 27-MAR-2024 INFO UPDATE.
PROSITE Doc. [info]	PDOC51320
Associated ProRule [info]	PRU00650

Name and characterization of the entry

Description [info]

Tify domain profile.

Matrix / Profile [info]

/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=36;
/DISJOINT: DEFINITION=PROTECT; N1=4; N2=33;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=1.1848539; R2=0.0092429; TEXT='NScore';
/NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=3274.9877930; R2=1.2482638; PRIORITY=1; TEXT='Heuristic 5.0%';
/CUT_OFF: LEVEL=0; SCORE=792; H_SCORE=4264; N_SCORE=8.5; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=576; H_SCORE=3994; N_SCORE=6.5; MODE=1; TEXT='?';
/DEFAULT: M0=-12; D=-100; I=-100; B1=-1000; E1=-1000; MI=-255; MD=-255; IM=-255; DM=-255;

...

                A   C   D   E   F   G   H   I   K   L   M   N   P   Q   R   S   T   V   W   Y
/I:         B1=0; BI=-255; BD=-255;
/M: SY='P';  M= 17,-35,-24, 19,-32,-13,-27,-21,-11,  3, -2,-24, 39,  0,  5, 10,  6,  2,-42,-31;
/M: SY='P';  M= 11,-35,  2, 16, -5,-16, 14,-20, -3,-25, -9, 12, 35,  5,-23, 19, 14,-19,-42,-26;
/M: SY='P';  M= 28,-36, 10, 15,-42, 24,-26,-25,-22,-36,-12, -6, 41,  5,-28, 18,-15,-23,-42,-35;
/M: SY='E';  M= 19,-36,  5, 34,-41, 17,-23,-35,  4,-24,-29,  4,  9, 15,-12,  9,  3,-24,-42,-33;
/M: SY='T';  M= 15,  9,  0,-11,-37, -7,-27,-27,-14,-32,-27, -5, 23, -6, -3, 33, 37, -1,-46,-32;
/M: SY='Q';  M= 27,-34, 10, 19,-40,-16,-22,-33,  9,-27,-27, 13, -5, 29, -1, 17, 12,-20,-43,-31;
/M: SY='Q';  M=-24,-48,-20,  2,-48,-31,-15,-25, -6,-35,-23, -3, 46, 87, 18,-15,-14,-37,-38,-28;
/M: SY='M';  M=-30,-33,-48,-40, 19,-47,-28,  9,-39, 60, 60,-43,-44,-32,-36,-39,-26, -4,-32,-12;
/M: SY='T';  M=-16,-25,-22,-24,-30,-32,-32,-18,-10,-25,-22,-11,-23,-25,-28, -1, 86,  3,-51,-29;
/M: SY='I';  M=-28,-39,-49,-46,-11,-52,-43, 75,-41, 26, 29,-40,-38,-37,-43,-37,-23, 14,-36,-19;
/M: SY='F';  M=-30,-34,-44,-41, 86,-40,-29,  2,-37, -2, 13,-34,-44,-40,-36, 10,-23,  0,-11, 24;
/M: SY='Y';  M=-36,-43,-37,-39, 56,-42, -5,-18,-31,-13,-13,-36,-47,-29,-28,-31,-29,-23,  7,101;
/M: SY='N';  M=  5,-37, 15,-10,-43, 44,-19,-42,-16,-41,-11, 44,-32, 34,  4,  5,-20,-38,-44,-33;
/M: SY='G';  M=-13,-40, -2,-36,-46, 86,-33,-54,-32,-49,-39,-13,-31,-30,-40,-13,-31,-47,-38,-41;
/M: SY='Q';  M=-19,-39,-16, 22,-42,-28,  4,-39, 32,-31,-27,-13,-28, 56, 27, 34, -6,-35,-40,-27;
/M: SY='V';  M= -4,  2,-41,-13, -7,-43,-37, 19,-33, -2, 58,-37,-38,-32,-35,-29,-17, 61,-45,-22;
/M: SY='C';  M= -5, 56,-34,-34, -2,-37, 20,  8,-30, 11,  7, -1,-42,-28,-17, -5,-14, 16,-26, 52;
/M: SY='V';  M= -9,-30,-43,-37, -4,-44,-44, 19,-14,  0,  5,-37,-40,-36,-35,-27,  1, 71,-47,-23;
/M: SY='F';  M=-34,-35,-46,-43, 90,-43,-28, -4,-39,  2,-13,-37,-46,-44,-37,-12,-15, -4, -7, 36;
/M: SY='D';  M=-27,-40, 75, 19,-46,-25, 17,-45,-15,-45,-39, 47, -1,  3,-23, -1,-18,-44,-59,-32;
/I:         I=-28; MD=-71;
/M: SY='D';  M=-21,-45, 51,  9,-44, 10,  3,-49,-24,-48,-42, 25,-10,-21,-17, 13,-17,-46,-52, -1; D=-28;
/I:         I=-28; MI=0; MD=-71; IM=0; DM=-71;
/M: SY='V';  M=-19, 17,-47,-42, 40,-47,-40, 31,-39, 11, -6,-41,-44,-41,-40,-32,-20, 55,-31, 11;
/M: SY='P';  M=-16,-39,-25,-19,-40,-20,  5,-32,-23,-30,-28,-21, 81,  2,-31, 18, 43,-30,-45,-34;
/M: SY='P';  M= 31,-39,-25,  6,-41,-26, 24,-29,-19,-34,-26,-26, 71,  4,  2, -5,-20, -4,-43,-33;
/M: SY='E';  M=-16,-41, 45, 58,-21,-18,-18,-37,-12,-11,-29,  9,-26, 26,-19, -3,-12,-35,-45,-30;
/M: SY='K';  M=-15,-40,-19,  1,-42,-18,-21,-40, 76,-38, -7,-12,-27, 23, 17,-12,-21,-36,-36,-28;
/M: SY='A';  M= 54,-27,-37,-30,-28,-25,-39, 13,-31,-15,-15,-31,-34,-29,-34, -7,-15, 45,-43,-30;
/M: SY='Q';  M=  7,  2, -2, 30,-43,-10,-19,-24, 23,-35,-26,  4,-29, 58, 19, -9,-22,-21,-40,-30;
/M: SY='E';  M= 24,-35, 19, 44,-18,-28,-22,-28, -6, -5,-25,  2, -6,-12, -9,  3, -7,-12,-40,-11;
/M: SY='I';  M=-17,-37,-26,-22,  0,-48,-41, 59,-36, 24, -2,-38,-16,-34,-20,-33,-21, 35,-38,-20;
/M: SY='M';  M=-27,  0,-44,-38, 17,-25,-26, 24,-23, 36, 78,-19,-40,-29,-32,-34,-24,  2,-32, -1;
/M: SY='R';  M=-12,-36,  5, -4, -6,-18, 31,-21, -6, 16, 11,-11,-35, 11, 32, 11, -1, -8,-41,-20;
/M: SY='L';  M=-28, -8,-43,-37, 22,-26, 11, 24,-33, 41, 38,-37,-13,-31, -5,-34,-25, 14,-32,  0;
/M: SY='A';  M= 58,-27,-33,-27, -2, -9,-32,-19,-27,  9,-17,-26,-33,-25,-17,  6,  2, -3,-37,-26;
/M: SY='S';  M= 17,-33,  8,-20,-19, 24,-23,-25,  4,-27,-29, 21,-31, -2,  7, 32,  9,-28,-42,-30;
/M: SY='R';  M=  9,-38, -7,  9,-39, 22, 11,-23, 14,-27,-27, 15,-31, 21, 34,  3, -4,-32,-42,-29;
/I:         E1=0; IE=-255; DE=-255;

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Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2024_02 which contains 571'282 sequence entries.

Total number of hits	53 in 51 different sequences
Number of true positive hits	53 in 51 different sequences
Number of 'unknown' hits	0
Number of false positive hits	0
Number of false negative sequences	0
Number of 'partial' sequences	0

Precision (true positives / (true positives + false positives))	100.00 %
Recall (true positives / (true positives + false negatives))	100.00 %

Comments [info]

Matrix type [info]	protein_domain
Scaling database [info]	reversed
Author [info]	CJA_Sigrist
Taxonomic range [info]	Eukaryotes
Maximum number of repetitions [info]	2
Feature key [info]	DOMAIN
Feature description [info]	Tify
Version [info]	5

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences

51 sequences

GAT17_ORYSJ (Q6Z433), GAT18_ORYSI (A2XKR7), GAT18_ORYSJ (Q10F25),

GAT19_ORYSI (B8AR30), GAT19_ORYSJ (Q0DNU1), GAT20_ORYSJ (Q5Z4U5), 
GAT24_ARATH (Q8GXL7), GAT25_ARATH (Q9LRH6), GAT28_ARATH (Q8H1G0), 
JAZ1_SOYBN  (C6TCZ5), JAZ7_SOLLC  (Q9M723), TI10A_ARATH (Q9LMA8), 
TI10A_ORYSJ (Q84R94), TI10B_ARATH (Q9S7M2), TI10B_ORYSI (A2YNP2), 
TI10B_ORYSJ (Q8H395), TI10C_ORYSI (A2Z1N3), TI10C_ORYSJ (Q69P94), 
TI11A_ARATH (Q9LDU5), TI11A_ORYSI (A2XD78), TI11A_ORYSJ (Q8GSI0), 
TI11B_ARATH (Q9C9E3), TI11B_ORYSJ (Q10QW3), TI11C_ORYSI (A2XD79), 
TI11C_ORYSJ (Q8GRS2), TI11D_ORYSI (A2Z6V9), TI11D_ORYSJ (Q7XEZ1), 
TI11E_ORYSI (A2Z6V6), TI11E_ORYSJ (Q7XEZ6), TI11F_ORYSJ (Q7XEZ4), 
TI11G_ORYSJ (Q94LG1), TIF3A_ARATH (Q9M246), TIF3B_ARATH (Q9C5K8), 
TIF3_ORYSJ  (Q7XPM8), TIF4A_ARATH (Q7XA73), TIF4B_ARATH (Q8GY55), 
TIF5A_ARATH (Q8LBM2), TIF5B_ARATH (O64687), TIF5_ORYSI  (A2YI92), 
TIF5_ORYSJ  (Q69NY7), TIF6A_ARATH (Q58G47), TIF6A_ORYSI (A2YVF1), 
TIF6A_ORYSJ (Q6ZJU3), TIF6B_ARATH (Q9LVI4), TIF6B_ORYSJ (Q6ES51), 
TIF7_ARATH  (Q8W4J8), TIF8_ARATH  (Q84MB2), TIF8_ORYSJ  (Q6Z2K1), 
TIF9_ARATH  (Q93ZM9), TIF9_ORYSI  (A2XSX6), TIF9_ORYSJ  (Q7XV97)

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Retrieve an alignment of UniProtKB/Swiss-Prot true positive hits:
[Clustal format, color, condensed view] [Clustal format, color]
[Clustal format, plain text] [Fasta format]
Retrieve the sequence logo from the alignment

PDB
[Detailed view]

1 PDB

8T2I