To improve security and privacy, we are moving our web pages and services from HTTP to HTTPS.
To give users of web services time to transition to HTTPS, we will support separate HTTP and HTTPS services until the end of 2017.
From January 2018 most HTTP traffic will be automatically redirected to HTTPS. [more...]
View this page in https
Entry: PS51325

General information about the entry

Entry name [info] ALPHA_BOX
Accession [info] PS51325
Entry type [info] MATRIX
Date [info] 01-JUL-2007 CREATED; 10-MAY-2017 DATA UPDATE; 25-OCT-2017 INFO UPDATE.
PROSITE Doc. [info] PDOC51325
Associated ProRule [info] PRU00655

Name and characterization of the entry

Description [info] Alpha box DNA-binding domain profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=59;
/DISJOINT: DEFINITION=PROTECT; N1=6; N2=54;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=3.8848138; R2=0.0188497; TEXT='NScore';
/NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=3052.2575684; R2=1.0101695; PRIORITY=1; TEXT='Heuristic 5.0%';
/CUT_OFF: LEVEL=0; SCORE=245; H_SCORE=3300; N_SCORE=8.5; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=139; H_SCORE=3193; N_SCORE=6.5; MODE=1; TEXT='?';
/DEFAULT: B1=*; E1=*; MM=*; II=*;
...
                A   C   D   E   F   G   H   I   K   L   M   N   P   Q   R   S   T   V   W   Y
/I:         B1=-85; E0=*; BM=-1; BD=-38;
/M: SY='K'; M=  9,-19,-20,-15,-20,-26,-14,  4, 17,-18,-11,-16,  3,-12,-17,  3, 12, 11,-23,-18; M0=-6;
/I:         MM=0; MI=-89; MD=-99; IM=-9; II=-11; DM=-7; DD=-14;
/M: SY='K'; M= 17,-27,-28,-24,-44,-28,-25,-41, 26,-41,-32,-24, 15,-22,-24, 12,-21,-33,-43,-38; M0=-19;
/I:         MM=0; MI=-89; MD=-99; IM=-9; II=-11; DM=-7; DD=-14;
/M: SY='K'; M=-36,-42,-44,-29,-51,-41,-20,-44, 32, -3,-34,-28,-40,-15, 23,-35,  4,-41,-39,-38; M0=-24;
/I:         MM=0; MI=-89; MD=-99; IM=-9; II=-11; DM=-7; DD=-14;
/M: SY='K'; M=-40,-44,-51,-33,-55,-43,-21,-47, 34,-43,-36,-30,-42,-17, 26,-38,-36,-45,-40,-40; M0=-32;
/I:         MM=0; MI=-89; MD=-99; IM=-9; II=-11; DM=-7; DD=-14;
/M: SY='P'; M=  2, 17,-13, -8,-29,-24,-11,-26, 13,-26,-17,-11, 22, 10,-11, 10,-13,-22,-29, 11; M0=-8;
/I:         MM=0; MI=-89; MD=-99; IM=-9; II=-11; DM=-7; DD=-14;
/M: SY='V'; M=-35,-29,-61,-57,-28,-59,-56, 21,-56, 20,-15,-56,-55,-52,-56,-53,-34, 23,-46,-44; M0=-33;
/I:         MM=0; MI=-89; MD=-99; IM=-9; II=-11; DM=-7; DD=-14;
/M: SY='N'; M=-53,-51,-48,-52,-62,-50,-53,-73,-59,-69,-66, 44,-55,-56,-58,-55,-56,-66,-55,-60; M0=-53;
/I:         MM=0; MI=-89; MD=-99; IM=-9; II=-11; DM=-7; DD=-14;
/M: SY='S'; M= 17,-28,  6,-26,-47, 12,-30,-45,-30,-46,-37,-25,  6,-27,-34, 24,-23,-36,-48,-43; M0=-19;
/I:         MM=0; MI=-89; MD=-99; IM=-9; II=-11; DM=-7; DD=-14;
/M: SY='F'; M=-55,-45,-59,-63, 41,-58,-20,-44,-58,-37,-38,-44,-56,-45,-52,-50,-54,-46, 26, 25; M0=-43;
/I:         MM=0; MI=-89; MD=-99; IM=-9; II=-11; DM=-7; DD=-14;
/M: SY='M'; M=-33,-28,-60,-56,-31,-58,-55, 30,-55,-18, 36,-54,-54,-53,-56,-51,-33, 16,-48,-44; M0=-35;
/I:         MM=0; MI=-89; MD=-99; IM=-9; II=-11; DM=-7; DD=-14;
/M: SY='A'; M= 22,-21,-44,-40,-24, 20,-30,  7,-37,  8,-15,-33,-36,-33,-35,-24,-21,-14,-30,-27; M0=-17;
/I:         MM=0; MI=-89; MD=-99; IM=-9; II=-11; DM=-7; DD=-14;
/M: SY='F'; M=-55,-45,-59,-63, 42,-58,-20,-44,-58,-37,-38,-44,-56,-46,-52,-50,-54,-46,-12, 26; M0=-43;
/I:         MM=0; MI=-89; MD=-99; IM=-9; II=-11; DM=-7; DD=-14;
/M: SY='R'; M=-61,-54,-62,-59,-66,-53,-50,-72,-43,-67,-64,-58,-57,-51, 43,-63,-61,-69,-55,-62; M0=-55;
/I:         MM=0; MI=-89; MD=-99; IM=-9; II=-11; DM=-7; DD=-14;
/M: SY='S'; M=  4, 22,-40,-37,-36,-28,-32,-32,-35,-35,-27,  7,-34,-32,-36, 28,  5,  4,-39,-36; M0=-19;
/I:         MM=0; MI=-89; MD=-99; IM=-9; II=-11; DM=-7; DD=-14;
/M: SY='Y'; M=-44,-37,-56,-56, 29,-53,-21,-30,-52,-26, 18,-43,-52,-42,-48,-45,-43,  4,-14, 39; M0=-33;
/I:         MM=0; MI=-89; MD=-99; IM=-9; II=-11; DM=-7; DD=-14;
/M: SY='Y'; M=-51,-43,-58,-60, -8,-55,-23,-39,-55,-32, 28,-45,-55,-46,-50,-49,-51,-42,-15, 46; M0=-41;
/I:         MM=0; MI=-89; MD=-99; IM=-9; II=-11; DM=-7; DD=-14;
/M: SY='S'; M=  1,-17,-40,-34,-15,-33,-23,  7,-31,  8, 16,-30,-34,-27,-29, 26,-18, -9,-22,-18; M0=-14;
/I:         MM=0; MI=-89; MD=-99; IM=-9; II=-11; DM=-7; DD=-14;
/M: SY='R'; M=-13,-27,  6, -7,-30,-23,-10,  1,  6, -4,-18,-10,  4, 11, 22,-12, 12,-24,-29,-23; M0=-7;
/I:         MM=-9; MI=-89; MD=-11; IM=-9; II=-11; DM=-7; DD=-14;
/M: SY='I'; M=-11,-10,-32,-26,-10,-26,-16, 22,-23, 14, -2,-23,-27,-20,-22,  7, 11, -1,-16,-12; M0=-10;
/I:         MM=-13; MI=-79; MD=-8; IM=-9; II=-11; DM=-31; DD=-2;
/M: SY='N'; M= -7,-15, -2, -3,-25,-13, -9,-24, -7,-25,-17, 27, 26, -6,-11, -7, -9,-19,-26,-20; M0=-9;
/I:         MM=0; MI=-67; MD=-77; IM=-9; II=-11; DM=-1; DD=-43;
/M: SY='I'; M=-35,-31,-60,-54, 11,-55,-45, 24,-52, 15, 18,-52,-51,-44,-49,-48,-34, 18,-36,-36; M0=-29;
/I:         MM=0; MI=-89; MD=-99; IM=-9; II=-11; DM=-7; DD=-14;
/M: SY='F'; M=-15,-17,-24,-19, 26,  1,-15,-13,  3,  6, -9,  6,-29,-15,-19,  1,-14,-12,-21, 20; M0=-7;
/I:         MM=0; MI=-89; MD=-99; IM=-9; II=-11; DM=-7; DD=-14;
/M: SY='N'; M=  2,-29,-12,  5,-32, 14,-10,-30,  7,-29,-20, 15, 13, -6,-12, 10,-14,-25,-31,-24; M0=-8;
/I:         MM=0; MI=-89; MD=-99; IM=-9; II=-11; DM=-7; DD=-14;
/M: SY='Q'; M=-13,-28,-12,  5,-31,  9,-10,  1, -6,-28,-19,  7,  3, 23,  6,  3,-13,  0,-30,-23; M0=-6;
/I:         MM=0; MI=-89; MD=-99; IM=-9; II=-11; DM=-7; DD=-14;
/M: SY='W'; M=-19,-17,-42, 10, 10,-34,-23, 19,-32, 16, -6,-31,-34,-28,-30,-25,-18,  7, 24,-18; M0=-14;
/I:         MM=0; MI=-89; MD=-99; IM=-9; II=-11; DM=-7; DD=-14;
/M: SY='H'; M=  1,-30,-17,-11,-34,-27, 25,-31,  8,-30,-22,-13, 23, -8,  7,-16, 18,-27,-32,-26; M0=-12;
/I:         MM=0; MI=-89; MD=-99; IM=-9; II=-11; DM=-7; DD=-14;
/M: SY='Q'; M=-38,-42,-40,-39,-38,-43,-35,-40,-28,-34, 18,-38,-47, 44,-28,-40,-40,-42,-42,-38; M0=-33;
/I:         MM=0; MI=-89; MD=-99; IM=-9; II=-11; DM=-7; DD=-14;
/M: SY='K'; M= 10,-31,-16,-10,-35,-26,-12,-32, 25,-31,-22,  9,-27, 10, 14,-16,  4,-27,-32,-26; M0=-12;
/I:         MM=0; MI=-89; MD=-99; IM=-9; II=-11; DM=-7; DD=-14;
/M: SY='E'; M=-13,-28,  5, 23,-31,-23, 16,-29,  7,-28,-19, -9,-24, 11,-11,  2,-13,  1,-30,  9; M0=-9;
/I:         MM=0; MI=-89; MD=-99; IM=-9; II=-11; DM=-7; DD=-14;
/M: SY='R'; M=-33,-35,-46,-31,-35,-41,-21,  4, 15, 22,-23,-30,-40,-18, 22,-34,-30,-29,-35,-33; M0=-20;
/I:         MM=0; MI=-89; MD=-99; IM=-9; II=-11; DM=-7; DD=-14;
/M: SY='S'; M=-32,-37,-52,-55,-57,-39,-51,-61,-57,-61,-54,-46,-46,-53,-54, 37,-37,-50,-55,-57; M0=-44;
/I:         MM=0; MI=-89; MD=-99; IM=-9; II=-11; DM=-7; DD=-14;
/M: SY='T'; M=  9,-28,-12, -6,-31, -1,-10,-29,  6,-28,-19,  8,  4, -5,  7, 10, 17,-24,-30,-23; M0=-7;
/I:         MM=0; MI=-89; MD=-99; IM=-9; II=-11; DM=-7; DD=-14;
/M: SY='I'; M=-16,-14,-39,-33,  9,-31,-20, 22,  1, 16, -6,-28,-32,-25,-27,-22,  4, -8,-19, 12; M0=-12;
/I:         MM=0; MI=-89; MD=-99; IM=-9; II=-11; DM=-7; DD=-14;
/M: SY='M'; M=-44,-38,-68,-63,-19,-67,-53, 25,-61, 24, 27,-64,-56,-48,-55,-61,-43,-20,-38,-40; M0=-38;
/I:         MM=0; MI=-89; MD=-99; IM=-9; II=-11; DM=-7; DD=-14;
/M: SY='R'; M= 12,-25,-33,-29,-44, 12,-29,-41,-27,-43,-34,-26,-33,-26, 21, 17, 14,-33,-45,-41; M0=-18;
/I:         MM=0; MI=-89; MD=-99; IM=-9; II=-11; DM=-7; DD=-14;
/M: SY='Q'; M=  2,-18,-20, 11,  7,-27,-14,  4, 12, -1,-10,-16,-27, 17,-17,-16,-14, 10,-22,-18; M0=-6;
/I:         MM=0; MI=-89; MD=-99; IM=-9; II=-11; DM=-7; DD=-14;
/M: SY='M'; M=-16,-14,-38,  2,  8,-31, 15, -9,-28, 18, 26,-27,-31,-24,-26,-22,-15,  5,-18, 11; M0=-12;
/I:         MM=0; MI=-89; MD=-99; IM=-9; II=-11; DM=-7; DD=-14;
/M: SY='W'; M=-70,-55,-65,-69,-51,-56,-56,-76,-69,-69,-69,-67,-60,-68,-64,-74,-71,-74, 63,-48; M0=-65;
/I:         MM=-1; MI=-37; MD=-99; IM=-2; II=-33; DM=-7; DD=-14;
/M: SY='Q'; M=  1,-28,-12, 13,-31, -1, 17,-29,  6,-28,-19,  8,-24, 17,-10,  2, 12,-24,-30,-23; M0=-8;
/I:         MM=0; MI=-89; MD=-99; IM=-9; II=-11; DM=-7; DD=-14;
/M: SY='H'; M= 10,-27,-13, -7,-30,-24, 24,-28,  7, -4,-18, 20,-24, 10,  6,-13,-13,  0,-29,-23; M0=-7;
/I:         MM=0; MI=-89; MD=-99; IM=-9; II=-11; DM=-7; DD=-14;
/M: SY='D'; M=-34,-55, 33, 23,-56,-31, 17,-56,-30,-54,-49,-17,-37,-23,-41,-30,-35,-51,-56,-45; M0=-31;
/I:         MM=0; MI=-89; MD=-99; IM=-9; II=-11; DM=-7; DD=-14;
/M: SY='P'; M=-21,-34,-19,-14,-39,-30, 17,-36, 15,-34,-26,-16, 29, 19, -9,  1,-21,-32,-35,-30; M0=-16;
/I:         MM=-1; MI=-37; MD=-99; IM=-2; II=-33; DM=-7; DD=-14;
/M: SY='F'; M=-15,-15,-33,-27, 26,-30, 26,-10,-24,-13, 18, 20,-31,-21,-24,-21,  5,  5,-19,-15; M0=-12;
/I:         MM=-28; MI=-89; MD=-2; IM=-9; II=-11; DM=-7; DD=-14;
/M: SY='Q'; M=-10,-16, -4, -3,-18,-14, -5,-18,  0,-18,-13, -5,-18, 36, -1, -9,-10,-16,-18,-13; M0=-9;
/I:         MM=0; MI=-61; MD=-72; IM=-9; II=-11; DM=-1; DD=-45;
/M: SY='H'; M=-38,-44,-47,-30,-53,-42, 37,-45, 30,-41,-35,-29,-41, 10, 10,-36,-34,-43,-39,-39; M0=-29;
/I:         MM=0; MI=-89; MD=-99; IM=-9; II=-11; DM=-7; DD=-14;
/M: SY='K'; M= 13,-28,-12,  5,-31,  1,-10,-29, 13,-28,-19,  8,-24, -5,-11,  9, 13,-24,-30,-23; M0=-8;
/I:         MM=0; MI=-89; MD=-99; IM=-9; II=-11; DM=-7; DD=-14;
/M: SY='K'; M=  2,-23,-15,  5,-25,-24,-11, 11, 17, -3,-15,  7,-25, -7,-13,  3,  4,  1,-26,-21; M0=-5;
/I:         MM=0; MI=-89; MD=-99; IM=-9; II=-11; DM=-7; DD=-14;
/M: SY='W'; M=-56,-46,-60,-63, -8,-57,-22,-46,-59,-39,-40,-46,-57,-47,-53,-52,-55,-48, 61, 17; M0=-46;
/I:         MM=0; MI=-89; MD=-99; IM=-9; II=-11; DM=-7; DD=-14;
/M: SY='S'; M=  8,-32, 15, 13,-35,-25,-13,-33,  6,-32,-23,  8,-27, -8,-15, 19,-16,-28,-34,-27; M0=-12;
/I:         MM=0; MI=-89; MD=-99; IM=-9; II=-11; DM=-7; DD=-14;
/M: SY='F'; M=-16,-14,-39,-32, 17,-31,-20, 13,-28, 16, -5,-27,-31,  7,  3,-22,-15,  6,-18, 13; M0=-11;
/I:         MM=0; MI=-89; MD=-99; IM=-9; II=-11; DM=-7; DD=-14;
/M: SY='M'; M=-34,-31,-57,-52, 20,-52,-37, 15,-48, 15, 33,-48,-48,-40,-45,-43,-33,-19,-30, 21; M0=-27;
/I:         MM=0; MI=-89; MD=-99; IM=-9; II=-11; DM=-7; DD=-14;
/M: SY='A'; M= 29, 22,-52,-54,-50,-28,-44,-48,-51,-51,-41,-36,-36,-45,-47,  3, 20,-36,-53,-52; M0=-31;
/I:         MM=0; MI=-89; MD=-99; IM=-9; II=-11; DM=-7; DD=-14;
/M: SY='Q'; M=-17,-31,-16,  5,-35,-26,-12,  1, 22,-31,-22,-13,-27, 23, 15,  2,-16,-27,-32,-26; M0=-12;
/I:         MM=0; MI=-89; MD=-99; IM=-9; II=-11; DM=-7; DD=-14;
/M: SY='A'; M= 17,-27,-13, 12,-29,-24, 15,-26, -7,-27,-18,-11,-25, 11,-12,  2,-13, 15,-29,-23; M0=-9;
/I:         MM=0; MI=-89; MD=-99; IM=-9; II=-11; DM=-7; DD=-14;
/M: SY='Y'; M=-56,-45,-59,-63, -6,-58,-21,-45,-58,-38,-39,-45,-57,-46,-52,-51,-54,-47, 43, 44; M0=-45;
/I:         MM=0; MI=-89; MD=-99; IM=-9; II=-11; DM=-7; DD=-14;
/M: SY='N'; M=-20,-27,-34,-37,-51,-28,-39,-49,-41,-51,-42, 31,-36,-37,-42, 21, 21,-37,-52,-50; M0=-28;
/I:         MM=0; MI=-89; MD=-99; IM=-9; II=-11; DM=-7; DD=-14;
/M: SY='C'; M=-15, 19,-35,-29, 18,-30, 16,  6,-25,  0, -6,  5,-31,-22,  4,  9,  5,  5,-18,-15; M0=-8;
/I:         MM=0; MI=-89; MD=-99; IM=-9; II=-11; DM=-7; DD=-14;
/M: SY='I'; M=  1,-16, 12,-21,-16,-29,-17, 28,-19,-14, 16,-21,-29,  8,-21,-19,-14,-10,-20, 11; M0=-10;
/I:         MM=0; MI=-89; MD=-99; IM=-9; II=-11; DM=-7; DD=-14;
/M: SY='R'; M= 10,-32,-29,-23,-39,-33,-20,-35,-10, -3,-28, 17,-35,-16, 33,-25,-24,-31,-36,-33; M0=-17;
/I:         B0=*; E1=-10;
» more

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2017_10 which contains 556'006 sequence entries.


Total number of hits 21 in 21 different sequences
Number of true positive hits 21 in 21 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 0
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 100.00 %

Comments [info]

Matrix type [info] protein_domain
Scaling database [info] reversed
Author [info] CJA_Sigrist
Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 1
Feature key [info] DNA_BIND
Feature description [info] Alpha box
Version [info] 5

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
21 sequences

FMR1_PODAS  (P35692    ), HMAL1_YEAST (P0CY07    ), MAT1_ALTAL  (O94160    ), 
MAT1_COCCA  (O13402    ), MAT1_COCCY  (Q9Y8D1    ), MAT1_COCEL  (Q9Y8C7    ), 
MAT1_COCHE  (Q02990    ), MAT1_COCKU  (Q9Y8D3    ), MAT1_COCSA  (Q9P446    ), 
MAT1_FUSOX  (O59851    ), MATA_NEUAF  (Q02292    ), MATA_NEUCR  (P19392    ), 
MTA1_SOREQ  (O13595    ), MTA1_SORFI  (O13596    ), MTA1_SORMK  (O42837    ), 
MTAL1_CANAL (Q9UW19    ), MTAL1_CANGA (Q874P0    ), MTAL1_KLUDE (Q874N0    ), 
MTAL1_KLULA (Q08398    ), MTAL1_PICAN (Q707Y7    ), MTAL1_YEAST (P0CY06    )
» more


View entry in original PROSITE format
View entry in raw text format (no links)
Direct ScanProsite submission