Entry: PS51350

Forthcoming changes to the profile format
General information about the entry

Entry name [info] PTS_HPR_DOM
Accession [info] PS51350
Entry type [info] MATRIX
Date [info] DEC-2007 (CREATED); OCT-2013 (DATA UPDATE); MAR-2014 (INFO UPDATE).
PROSITE Doc. [info] PDOC00318
Associated ProRule [info] PRU00681

Name and characterization of the entry

Description [info] PTS HPR domain profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=88;
/DISJOINT: DEFINITION=PROTECT; N1=6; N2=83;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=2.6502614; R2=0.0069629; TEXT='NScore';
/NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=9670.06962; R2=23.33031; TEXT='HScore';
/CUT_OFF: LEVEL=0; SCORE=841; N_SCORE=8.5; H_SCORE=25931; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=553; N_SCORE=6.5; H_SCORE=22572; MODE=1; TEXT='?';
/DEFAULT: M0=-63; D=-100; I=-100; B1=-1000; E1=-1000; MI=-255; MD=-255; IM=-255; DM=-255;
...
                A    C    D    E    F    G    H    I    K    L    M    N    P    Q    R    S    T    V    W    Y
/I:         B1=0; BI=-255; BD=-255;
/M: SY='M'; M=  -2,-154, -60,   4,-141, -44, -87, -36, -50,-101, 120, -33, -19, -10, -57, -44,  -7, -11,  40, -85;
/M: SY='V'; M=  16, -56, -73,   6, -32,-154,  13,  18, -18,  20,   2,-108,  19,  22, -49, -77, -53,  31,-152,  17;
/M: SY='E'; M= -50, -31, -82,  53,-151, -91, -50, -25,  13,-149, -37, -79,-118,  39,  18,  52,  28, -39,-156,   5;
/M: SY='R'; M=  10, -28, -91, -42,  15, -15, -66, -42,  46, -29,-138, -28,-151,  38,  61, -79, -25,  -5,-152, -81;
/M: SY='E'; M= -54, -21,  14,  60,-127,-150, -25, -25,   7, -54,-143, -38,-121,  37,  11,   6,  53, -41,-162,-146;
/M: SY='V'; M=  -2, -54,-161, -88,  57,-159, -95,  38,-106,   3, -48,-155,-158,-155,-155,-106,  -9,  63,  53, -57;
/M: SY='T'; M= -65,-150, -43,  21, -34, -59,  21,   7,  -5, -32, -71, -44, -38, -20, -17, -54,  75,  32,-162,-142;
/M: SY='I'; M=-104,  11,-164,-160,   7,-166,-161,  83,-157,   9, -52,-157, -64,-156,-159, -86,-137,  59,-155, -95;
/M: SY='T'; M=  13, -11, -23, -48, -99, -17, -53,  26,  21, -51, -49,  -9,  -2,  -8,  19, -26,  33,  23, -78, -67;
/I:         I=-26; MI=0; MD=-65; IM=0; DM=-65;
/M: SY='N'; M=  12, -16,  10,-137,-147, -96,  24, -67, -92, -19,-143, 101, -75, -43,-123,  10, -74, -96,  33,   3;
/M: SY='P'; M=  -6,-158,  -7,  37, -99, -53, -34, -99,  44, -83,-147, -12,  72, -23,  26,   6, -55, -89,-159,-150;
/M: SY='H'; M= -27,-151, -48, -56, -75, -31,  67, -17, -31,  28, -73,  44,-151, -19,  14,   3,  25,   3, -54,-138;
/M: SY='G'; M= -98,-156, -92, -91,-161, 105,-149,-169, -80,-165,-155, -13,-148,-146,-155, -68,-146,-163,-154, -62;
/M: SY='L'; M= -46,-150, -77,-156, -46,-164,-150,  39,-154,  82,  28,-159,-160,-149, -46,-154,-141, -32, -70,-133;
/M: SY='H'; M= -76,-159, -93,-107, -95, -83, 151,-163,-137,-117,-134, -85, -55, -12,-132, -37, -59,-162,-179,-119;
/M: SY='A'; M=  95,-142,-147,-141,-151, -62,-149, -67,-142, -84,-139,-141, -84,-140, -93, -23,  14,  -7,-156, -81;
/M: SY='R'; M= -84,-162,-142,-131,-106,-156,  13,-161, -73,-154,-143,-101,-154, -45, 120,-102, -60,-155,-155, -66;
/M: SY='P'; M=  39,-160,-147, -99,-159, -79, -80, -50,-142, -95,-145, -88, 116, -40,-152, -49, -99, -31,-158, -71;
/M: SY='A'; M=  95, -89,-145,-139,-154, -33,-147,-103,-140, -83,-142,-138,-146,-137, -45,  39, -58,-134,-156,-150;
/M: SY='A'; M=  76,-144, -48, -72,-153, -32, -56, -82, -32,-146, -13, -42,-145,  -9,-143,  35,  45, -43, -16,-147;
/M: SY='K'; M=  -7, -70, -74, -19,-142,-153,  13,  -4,  50,  24,  38, -69, -32,  24,  29, -61, -16,  -4,-155, -62;
/M: SY='F'; M= -47, -88,-166,-159,  70,-164,-153,  42,-157,  63, -67,-160,-161,-156,-156,-154, -92, -15,  43,-122;
/M: SY='V'; M=  34,-146,-152, -44, -42,-124,-154, -55, -55, -82, -54, -59,-153, -95, -23, -14,   5,  87,-162, -67;
/M: SY='Q'; M= -14,-156, -27,  41, -93, -27,   4,-117,  49, -98,-144,  19,-145,  74,  20, -27, -13, -71,-157, -68;
/M: SY='T'; M=  38, -12,-143,  28, -24, -96, -86, -52,   7,  36,   5,-142,-148, -49,-118, -72,  42,  13,-156,-141;
/M: SY='A'; M=  88,  21,-151,-144, -38,-137,-151, -41,-145, -24, -37,-145, -74,-143,-149, -40, -42,  32,-157,-146;
/M: SY='S'; M=  10,-151, -25, -13,-156,  -2, -47,-110,  52,-119,-146,  29,-145,  21,  24,  52, -11, -76,-158,-146;
/M: SY='K'; M= -25,-155, -32,  26,-156,  23, -76, -91,  56, -73,-145, -12, -23,  30,  46,   4,   1,-151,-156, -67;
/M: SY='F'; M= -40, -75,-158, -48, 111,-158,   8, -42,-151, -32,-130,-151,-161, -45, -63, -42, -58,-134,   2,  56;
/I:         I=-26; MI=0; MD=-65; IM=0; DM=-65;
/M: SY='D'; M=  -1, -97,  53,  24,-159, -10, -23,-100,  31,-107, -60,  30,  11,  37, -17,  23, -25,-124,-161,-148;
/M: SY='S'; M=  54,  62, -60,-111,-152, -33, -68,-119, -30, -71,-101,-132,-147,-135,-143,  85, -78, -37,-161,-148;
/I:         I=-29; MI=0; MD=-74; IM=0; DM=-74;
/M: SY='D'; M= -43,-156,  66,  58,-158,-103,  13,-106,   0,-111, -87,  -5, -10,  25,   9,   7,  14, -86,-163, -64;
/M: SY='I'; M= -30, -81,-162,-158, -40,-164,-161,  83,-155,  -3, -30,-155,-155,-154,-157, -89, -62,  69,-157,-137;
/I:         I=-30; MI=0; MD=-77; IM=0; DM=-77;
/M: SY='T'; M= -97, -49, -71,   8,   8,-128,  24, -39, -12, -15, -60, -14,-128,  36,  28,   0,  69, -47,  46, -17;
/I:         I=-29; MI=0; MD=-74; IM=0; DM=-74;
/M: SY='I'; M= -84,-150,-164,-158, -25,-165,-157,  61,-156,  53,  -4,-159,-158,-153,-156,-151,-137,  60,  30,-133;
/I:         I=-10; MI=0; MD=-27; IM=0; DM=-27;
/M: SY='R'; M=  -9,-155, -49,  46, -53, -49,  27,   9, -69, -67,-140,-138,-149, -35,  47,  -6,  43,   6,-163,-145; D=-10;
/I:         I=-10; MI=0; MD=-27; IM=0; DM=-27;
/M: SY='K'; M=  -6, -13,-138,-136, -12,-147,  35,-151,  59,-120, -11,  54,-153, -32,  28,   1, -89, -49,-151,  45; D=-10;
/I:         I=-10; MI=0; MD=-27; IM=0; DM=-27;
/M: SY='D'; M= -40,-159,  72,  -4,-165,  41,-137,-164,  -8,-106,-155,  64,-150,  20, -18, -92,-140,-161,-169,-154; D=-10;
/I:         I=-10; MI=0; MD=-27; IM=0; DM=-27;
/M: SY='G'; M=-135,-158,  44,   7,-165,  83,-144,-168,-143,-166,-157,  16, -43, -22,-150,  -3, -59,-163,-162,-157; D=-10;
/I:         I=-10; MI=0; MD=-27; IM=0; DM=-27;
/M: SY='K'; M= -32, -77, -64,  21,-153, -96, -21, -75,  67, -63, -24,  -3, -48,  28,  63, -73, -32, -18, -46, -36;
/I:         I=-29; MI=0; MD=-74; IM=0; DM=-74;
/M: SY='S'; M= -17,  -4, -66,  25,-127, -59, -22, -75,  23, -42, -84, -48,  14,  27,   9,  42,  33,   1,  20,-144;
/I:         I=-28; MI=0; MD=-71; IM=0; DM=-71;
/M: SY='V'; M=  62, -84, -84,-149,-103, -31,-156,   7,-149, -87, -45,-149, -71,-148,-152, -70, -34,  78,-160, -76;
/I:         I=-32; MI=0; MD=-81; IM=0; DM=-81;
/M: SY='N'; M= -57,-151,  69,  -2,-158, -45,-131,-155, -89, -67,-151,  91, -21, -64,-140,  41, -47, -78,-171,-150;
/M: SY='A'; M=  83, -35,-149,-145,-149,  38,-150, -34,-146,   4, -54,-142, -17,-143,-150,-108, -58, -48,-155,-149;
/M: SY='K'; M= -13,-154,   4, -60,-157, -34,-138, -64,  95,-123, -75, -48, -89, -50,  24, -37,  14,-149,-155,-146;
/I:         I=-27; MI=0; MD=-68; IM=0; DM=-68;
/M: SY='S'; M=-123,-145, -10,-134,-155, -75,-137,-154, -40,-157,-150,   5, -75, -41, -48, 110,-117,-147,-162,-146;
/M: SY='I'; M= -15,-151,-160,-155, -89,-159,-154,  74,-153,  43,  35,-153, -33, -64,-154,  -3, -79,  29,-155,-137;
/M: SY='M'; M= -66,-149,-158,-153,   6,-106,-142,  20,-149,  38, 116,   5,-154,-144,-149, -49, -36,  11,-152,-131;
/M: SY='G'; M=  34, -61, -44, -11,-157,  62,-141,-156,  30,-108,   0,   3, -82, -12,  -7,  29, -95,-149,-156,-150;
/M: SY='L'; M=-141,-149,-164,-157,-125,-165,-155,  58,-156,  64,   5,-159,-159,-152,-156,-152,-137,  57,-155,-135;
/M: SY='M'; M=  -8,-148,-159,-150, -36,-156,-141,  14,-148,  51, 116,-151,-153,  12,-147,-147, -65, -10,-151,-132;
/M: SY='M'; M=  23,-146,-144,-100,-145,  20,-140, -49,-103, -31,  90,-108,-145,  23, -30,  52,  40, -99,-156,-141;
/M: SY='L'; M= -31,-147,-161,-101, -58,-109,-147, -79,-155,  93,  -6,-159,-160,-148,-153,-114, -33, -38,-150,-133;
/M: SY='G'; M=  44,-151,  19, -17, -45,  79,-144,-158, -26,-156, -87, -32,-146,   4, -45, -40,-139, -88,-155,-150;
/M: SY='A'; M=  64, -28,-152,-147, -60,-122,-152,  28,-147,  19, -66, -93,-151,-144,-150,   0,  -1,  46,-156,-141;
/M: SY='K'; M=  17, -39, -67, -27,-151,  31,   1, -76,  39, -36, -99, -63, -12,  23,  37,  24,   1, -51,-154, -33;
/M: SY='Q'; M= -24,  26,-136,   6, -46, -29,  38, -45,  56, -52, -20, -27,   6,  75,   3, -36, -44, -81,-152,  -3;
/M: SY='G'; M=-116,-155, -28,-103,-160, 100, -15,-166, -64,-135,-152,  31, -18, -27,-150,-128,-144,-162, -31,-108;
/M: SY='D'; M=  16,   0,  68,  15,-155, -47,  30, -50,  -9,-150, -58, -43,-144,  -1, -32,  20,  51, -64,-165,-116;
/M: SY='E'; M= -51, -68,  -6,  55, -61,-110,   1, -48,  17, -21,   0, -25, -76,  17,  27,  10,  40, -12,-158, -52;
/M: SY='I'; M= -56,  46,-163,-158, -40,-164,-159,  71,-156,  34, -38,-156,-158,-154,-157,-149, -83,  63,-157,-137;
/M: SY='T'; M= -67,-104, -18,  48, -56,-117,   4, -42,  -4, -23, -70, -54,-144,  46,  28, -48,  67,  -5,-159, -66;
/M: SY='I'; M=-141, -78,-164,-159,  26,-166,-157,  72,-156,  44, -71,-158,-158,-155,-157,-151,-137,  58,-151,-131;
/M: SY='S'; M= -39, -11, -83,  22, -88, -90,  15,  24, -21, -13, -32, -48,-147,  -8,  28,  46,  36,   4, -84, -36;
/I:         I=-21; MD=-53;
/M: SY='A'; M=  82,  34,-151,-146, -83, -37,-153,  22,-146, -87,-136,-143,-149,-144,-151, -29,  16,  10,-159,-148; D=-21;
/I:         I=-21; MD=-53;
/M: SY='E'; M= -44,-156,  44,  66, -79,-148, -47, -25, -13,-120, -82, -15, -60,  18, -12,  33,  20, -58, -36, -90; D=-21;
/I:         I=-21; MI=0; MD=-53; IM=0; DM=-53;
/M: SY='G'; M=-102,-158,-113, -70,-163, 103,-152,-168,-150,-119,-155,-101, -42,-148,-158, -57, -78, -70,-156,-159; D=-21;
/I:         I=-21; DM=-53;
/M: SY='P'; M=   7, -79,  35,  53,-156, -55, -38, -36, -17, -67, -35, -23,  65, -30, -43,  29, -14, -64, -70,-149;
/M: SY='D'; M= -81,-159, 109,   8,-115, -22, -46, -46, -27,-123,-154, -17,-146,  37, -64, -70, -92,-157,-171,-102;
/M: SY='A'; M=  79, -12, -25,  77,-158, -74,-141,-151,-132,-150, -56, -59, -81,-127,-109, -57,-135,-102,-158,-151;
/M: SY='E'; M=  19,-155,  37,  65,-158, -83, -19, -68,  14, -64,-144, -19, -37,  57, -29, -17, -47, -21,-160,-147;
/M: SY='E'; M=  35,-154,  28,  67,-154,-127, -77, -54,  -8, -14,-141, -54, -60,  55,   0, -60, -47, -44, -42,-146;
/M: SY='A'; M=  99, -73,-104,-141, -54, -66,-150, -55,-143, -51, -66,-143,-147,-140,-148,-123, -38,  -7,-155,-148;
/M: SY='L'; M= -18,  13,-161,-154, -29,-160, -11,  30,-109,  66,  51, -72,-159,-123, -75, -89,-139,  33,-154, -67;
/M: SY='D'; M=  25,-155,  63,  50, -24,-114, -20, -71,  -3, -79, -19,  -2, -42,  50, -16, -35, -40, -75,-160,-144;
/M: SY='A'; M=  75, -39, -73,  26,-125, -26,   9, -88,   8, -93,-141, -48,-146, -21,   2, -28, -10, -15,-157, -55;
/M: SY='L'; M=-144,-150,-164,-158,   0,-166,-153,  55,-157,  74, -24,-160,-160,-153,-156,-154,-140,  27,-151,-132;
/M: SY='A'; M=  36,  22, -77,  29,-116,  -5,-145,   1,  14,  -6, -42,-132,-147,   9, -33,   8,  12,  12,-158,-145;
/M: SY='E'; M=  42, -48,  38,  49,-119, -54, -18, -80,   9, -72,-145,  12, -25,  34,  -4, -24, -16, -82,-160,-101;
/M: SY='L'; M=  18, -94,-157, -30,  29,-156,-147, -12,-151,  68,   5,-117,-157,-147, -91,-145,   3,  -7,  15,   1;
/I:         I=-27; MI=0; MD=-68; IM=0; DM=-68;
/M: SY='I'; M= -14,-150,-164,-158,  43,-162, -90,  63,-156,  45,  33,-157,-158,-153,-156,-150,-139,  36,-148,-129;
/M: SY='E'; M=  35,-152,   7,  59,-158, -72, -86,-117,   3,-134,-146,  44,-144,  30,  -1,  13, -10, -43,-161,-112;
/M: SY='D'; M=  19, -58,  41,  25,-158, -48, -29,-155,   4, -91,-148,  38,-147,  32, -11,  37,  -8, -69,-163, -43;
/I:         I=-22; MD=-57;
/M: SY='G'; M= -41,-160,  23,  14, -97,  48,  22,-162,  31, -53,-151,  19, -45, -43,  30, -60, -55,-101,-162, -42; D=-22;
/I:         I=-22; MI=0; MD=-57; IM=0; DM=-57;
/M: SY='F'; M= -12, -31,-165, -71,  93,-140,   3, -27,-105,  42, -87,-133, -50, -60,-157, -84,-148, -81,-139, -54;
/M: SY='G'; M= -20,-162,  55, -43,-164,  66, -35, -21,-114,-111,-156, -32, -12, -70, -65, -31, -22, -81,-167, -58;
/M: SY='E'; M=  -7,-167, -16,  96, -92,-161, -12,-118, -11, -78,-157,-104,-147,-127, -76,-119,-148, -49,-169,-158;
/M: SY='E'; M=  -3, -28,  16,  36,-170,  10, -51, -87, -44, -44, -62, -58,  -9, -32, -69, -11, -31, -19,-177,-165;
/I:         E1=0; IE=-255; DE=-255;
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Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2014_04 which contains 544'996 sequence entries.


Total number of hits 78 in 77 different sequences
Number of true positive hits 78 in 77 different sequences
Number of 'unknown' hits
Number of false positive hits
Number of false negative sequences 0
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 100.00 %

Comments [info]

Matrix type [info] protein_domain
Scaling database [info] reversed
Author [info] CJA_Sigrist
Taxonomic range [info] Prokaryotes (Bacteria)
Maximum number of repetitions [info] 2
Feature key [info] DOMAIN
Feature description [info] HPr
Version [info] 2

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
77 sequences

CRH_BACHD   (Q9K708), CRH_BACSU   (O06976), DHAM_ECOLI  (P37349), 
PTFAH_ECO57 (P69812), PTFAH_ECOLI (P69811), PTFAH_HAEIN (P44715), 
PTFAH_SALTI (Q8Z591), PTFAH_SALTY (P17127), PTFAX_ECO57 (Q8XBQ8), 
PTFAX_ECOL6 (Q8FFD8), PTFAX_RHOCA (P23388), PTFAX_SHIFL (Q83QP3), 
PTFAX_XANCP (P45597), PTFX1_ECOLI (P77439), PTFX2_ECOLI (P32670), 
PTHP_BACHD  (Q9K8D2), PTHP_BACME  (O69250), PTHP_BACSU  (P08877), 
PTHP_BACTI  (Q9F166), PTHP_BORBU  (O51507), PTHP_BUCAI  (Q9WXI5), 
PTHP_BUCAP  (Q8KA49), PTHP_BUCBP  (Q89B03), PTHP_CHLMU  (Q9PK56), 
PTHP_CHLPN  (Q9Z9E4), PTHP_CHLTR  (O84341), PTHP_CUPNH  (P23537), 
PTHP_ECO57  (P0AA06), PTHP_ECOL6  (P0AA05), PTHP_ECOLI  (P0AA04), 
PTHP_ENTFA  (P07515), PTHP_GEOSE  (P42013), PTHP_HAEIN  (P43921), 
PTHP_KLEPN  (P16481), PTHP_LACCA  (Q9KJV3), PTHP_LACLA  (Q9CJ83), 
PTHP_LACLC  (Q9ZAD9), PTHP_LACSK  (O07125), PTHP_LISIN  (P0A439), 
PTHP_LISMO  (P0A438), PTHP_LYSSH  (Q84F84), PTHP_MYCCT  (P45611), 
PTHP_MYCGE  (P47287), PTHP_MYCPN  (P75061), PTHP_NEIMA  (P65876), 
PTHP_NEIMB  (P65877), PTHP_PSEAE  (Q9HVV2), PTHP_PSEPU  (Q9Z426), 
PTHP_SALTI  (P0AA08), PTHP_SALTY  (P0AA07), PTHP_SHIFL  (P0AA09), 
PTHP_STAAC  (Q5HH02), PTHP_STAAM  (P0A0E1), PTHP_STAAN  (P99143), 
PTHP_STAAR  (Q6GI02), PTHP_STAAS  (Q6GAD1), PTHP_STAAU  (P0A0E3), 
PTHP_STAAW  (P0A0E2), PTHP_STACA  (P23534), PTHP_STAXY  (Q9EYQ9), 
PTHP_STRCO  (O50515), PTHP_STREI  (Q9WXK8), PTHP_STRMU  (P45596), 
PTHP_STRSA  (P24365), PTHP_STRSL  (P24366), PTHP_TREPA  (O83598), 
PTHP_VIBCH  (Q9KTD6), PTHP_XYLFA  (Q9PDH6), PTHP_XYLFT  (Q87DQ0), 
PTSO_ECO57  (P0A9N2), PTSO_ECOL6  (P0A9N1), PTSO_ECOLI  (P0A9N0), 
PTSO_KLEOX  (P51185), PTSO_PROMH  (Q9ZA86), PTSO_SHEVD  (Q9S0K8), 
PTSO_SHIFL  (P0A9N3), PTSO_VIBCH  (Q9KP46)
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PDB
[Detailed view]
47 PDB

1CM2; 1CM3; 1FU0; 1GGR; 1HDN; 1J6T; 1JEM; 1K1C; 1KA5; 1KKL; 1KKM; 1MO1; 1MU4; 1OPD; 1PCH; 1PFH; 1POH; 1PTF; 1QFR; 1QR5; 1RZR; 1SPH; 1TXE; 1VRC; 1Y4Y; 1Y50; 1Y51; 1ZVV; 2AK7; 2FEP; 2HID; 2HPR; 2JEL; 2LRK; 2LRL; 2NZU; 2NZV; 2OEN; 2RLZ; 2XDF; 3CCD; 3EZA; 3EZB; 3EZE; 3OQM; 3OQN; 3OQO
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