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PROSITE entry PS51386
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General information about the entry
| Entry name [info] | RINT1_TIP20 |
| Accession [info] | PS51386 |
| Entry type [info] | MATRIX |
| Date [info] |
01-MAY-2008 CREATED;
01-OCT-2013 DATA UPDATE; 29-MAY-2024 INFO UPDATE. |
| PROSITE Doc. [info] | PDOC51386 |
| Associated ProRule [info] | PRU00717 |
Name and characterization of the entry
| Description [info] | RINT1/TIP20 domain profile. |
| Matrix / Profile [info] |
/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=596; /DISJOINT: DEFINITION=PROTECT; N1=6; N2=591; /NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=2.5152988; R2=0.0104854; TEXT='NScore'; /CUT_OFF: LEVEL=0; SCORE=714; N_SCORE=10.0; MODE=1; TEXT='!'; /CUT_OFF: LEVEL=-1; SCORE=381; N_SCORE=6.5; MODE=1; TEXT='?'; /DEFAULT: M0=-24; D=-100; I=-100; B1=-1000; E1=-1000; MI=-255; MD=-255; IM=-255; DM=-255; ... A C D E F G H I K L M N P Q R S T V W Y /I: B1=0; BI=-255; BD=-255; /M: SY='W'; M= 18, -49, -43, -6, -41, -51, -35, -43, -2, -56, -42, 9, -55, 26, 6, 15, 32, -1, 54, 24; /M: SY='L'; M= 24, 23, -10, 25, -48, -57, 20, -35, 0, 29, -22, -10, -13, -28, -42, -29, -14, -35, -77, -54; /M: SY='S'; M= 38, -46, 10, -11, -50, -39, 3, -63, -5, -40, -52, 11, -5, -2, -40, 44, -18, -49, -61, 13; /M: SY='I'; M= -16, -53, 18, 13, -46, 5, -65, 39, -57, 20, -17, -48, -67, -44, -63, -7, -10, -1, -80, -60; /M: SY='L'; M= -26, -60, -13, 13, -8, -21, -50, -10, 7, 26, -19, -14, -3, 19, -12, -17, -17, -1, -70, -50; /M: SY='R'; M= -7, -65, 16, 10, -19, -59, -43, -15, 20, -39, -43, -37, 35, 3, 44, -1, -10, -26, -74, -56; /M: SY='Y'; M= -16, -58, 13, 34, -30, -60, -37, -12, -45, -10, -39, 4, 38, -30, -53, 11, 3, -19, -49, 45; /M: SY='C'; M= 23, 38, 1, -8, -61, -24, -6, -39, 26, -18, 5, -40, -54, 25, 6, -26, 3, -5, -72, -61; /M: SY='H'; M= 5, -59, 14, -8, -49, -18, 43, -11, -16, -2, -33, -7, -59, 20, 15, -8, 3, -19, -66, -7; /M: SY='W'; M= -29, 9, -28, -61, -2, -74, -55, 12, -25, 36, -11, 16, -75, -51, -58, -47, -16, 16, 44, 14; /M: SY='A'; M= 31, -48, -4, -9, -59, -9, -50, -18, 8, -5, -33, 3, -54, -2, -9, 12, -7, 4, -76, -63; /M: SY='D'; M= -19, -70, 47, 15, -66, -11, 44, -80, 0, -77, -58, 17, -12, 40, -10, 4, 4, -66, -71, -13; /M: SY='F'; M= -46, -52, -68, -24, 54, -79, 38, -17, -33, 29, -15, -58, -73, -45, -56, -19, 11, 11, -42, 14; /M: SY='R'; M= 3, -56, -13, 2, -17, -5, 28, -19, 0, -17, -36, -40, -59, -28, 36, 13, -13, 11, -70, -45; /M: SY='T'; M= 28, -47, -16, 8, -54, -53, -51, -8, 11, -2, 27, -11, -53, -2, -37, -18, 39, -15, -72, -62; /M: SY='R'; M= -46, -67, 18, 4, 4, -21, 25, -1, -8, 10, -28, -39, -66, -4, 43, -15, -13, -35, -67, -39; /M: SY='L'; M= -18, -51, -79, -69, 15, -77, -66, 10, -29, 54, -1, -23, -74, -53, -25, -30, -43, 5, -63, -37; /M: SY='S'; M= 24, -51, 7, 21, -65, -47, -3, -31, -8, -26, -42, -32, -50, 19, 16, 34, 13, -23, -74, -59; /M: SY='S'; M= 29, -52, 10, 33, -74, -43, -1, -70, -3, -70, -54, -8, 17, 30, -35, 35, 13, -51, -76, -62; /M: SY='L'; M= -44, -53, -65, -51, -1, -72, -53, -7, 11, 45, 18, -16, -68, -3, -42, -12, 16, -13, -59, -4; /M: SY='Q'; M= -5, -65, -12, 23, -69, 43, 27, -34, -15, -35, -44, -10, -57, 46, -16, -8, 6, -32, -74, -59; /M: SY='W'; M= -27, -67, 13, 3, -33, -27, -50, -22, -51, -63, -42, 5, -70, 12, -17, -44, -17, -51, 140, -10; /M: SY='P'; M= -2, -61, -11, -11, -10, -24, -4, -62, -1, -65, -54, -44, 80, 1, -18, 18, -14, -31, -57, 18; /M: SY='P'; M= 5, -60, -8, 8, -3, -17, 1, -59, 5, -60, -12, 27, 62, 1, -38, -10, 8, -33, -71, -47; /I: I=-15; MI=0; MD=-39; IM=0; DM=-39; /M: SY='M'; M= 13, -52, -57, 3, -50, -63, -59, 14, 3, 10, 28, -56, -3, -8, -20, -3, -13, 3, -74, -63; D=-15; /I: I=-15; DM=-39; /M: SY='T'; M= 19, -51, -18, -41, 0, -56, -53, -8, 19, 2, -29, -45, -58, -34, 22, 1, 23, -15, -69, -46; D=-15; /I: I=-15; DM=-39; /M: SY='P'; M= 7, -59, 35, 11, -74, -52, -53, -53, -6, -42, -52, -7, 63, -32, -46, 17, 7, -14, -84, -72; D=-15; /I: I=-15; DM=-39; /M: SY='Q'; M= -25, -53, -55, -37, -1, -68, 27, 22, -40, -9, 9, 5, -10, 43, -16, -15, 21, 1, -63, -39; D=-15; /I: I=-15; DM=-39; /M: SY='M'; M= -17, -54, -50, 16, -13, -22, -6, 2, -23, 26, 31, -50, -8, -4, -14, 14, -14, -11, -67, -49; /M: SY='S'; M= -32, -58, 19, 18, -61, -15, -47, -23, 15, 0, -35, 28, -4, -27, -36, 28, -9, -9, -84, -64; /M: SY='Q'; M= 6, -61, 7, 28, -21, -55, 10, -29, 5, -23, -39, -34, -54, 40, 32, 18, -30, -27, -69, -49; /M: SY='E'; M= -4, 13, 10, 34, -11, -59, 27, -10, -46, 9, -30, 23, -63, -28, -51, -1, -12, -19, -65, 1; /M: SY='V'; M= -27, -49, -20, -50, 13, -73, -1, 15, -56, 24, -14, 15, -72, 2, -59, -42, 0, 30, -54, 11; /M: SY='E'; M= -41, -73, -3, 42, -12, 28, 8, -32, -1, -36, -49, 19, -63, 1, 25, -15, -41, -32, -66, 0; /M: SY='W'; M= -5, -61, -9, 27, -45, -7, -44, -22, 10, -3, -33, -43, -8, 18, -6, 0, -2, -24, 62, -1; /M: SY='V'; M= -2, -45, -24, -47, -13, -18, -54, 20, -29, 9, -20, -12, -63, -11, -54, 19, 10, 24, -62, -4; /M: SY='S'; M= 23, -44, -14, 4, -58, -45, -47, -23, -18, -1, -33, -11, -51, -6, -15, 44, 30, -20, -74, -60; /M: SY='E'; M= -1, -71, -1, 60, -77, -16, 25, -38, 15, -70, -53, -7, 15, 35, -7, 0, -35, -55, -83, -61; /M: SY='R'; M= 30, -49, -56, -15, -53, -55, 5, 12, -14, -7, 32, -14, -56, -3, 32, -12, -10, -1, -68, -55; /M: SY='L'; M= -8, -58, -11, -21, -15, -68, -58, 0, 2, 37, -14, -25, 30, -39, 9, -22, -42, -11, -72, -53; /M: SY='W'; M= 0, -60, -37, -3, -14, 26, -45, -54, 1, -30, 16, 42, -64, -30, 7, -11, -37, -33, 81, -38; /M: SY='W'; M= -36, -65, 5, 17, -58, 4, -51, -62, -47, -47, -49, 2, 69, -1, -53, -3, 16, -31, 90, -44; /M: SY='P'; M= -37, -67, -38, 35, -56, -65, -47, -43, 19, 20, -26, -47, 56, 19, -4, 4, -15, -45, -79, -67; /M: SY='M'; M= -48, -56, -12, -47, 20, -72, -4, 16, 21, 22, 49, -11, -69, -35, -10, -13, -39, -11, -60, -34; /M: SY='R'; M= -23, -64, 8, 21, -42, -32, -38, -35, 10, 0, -32, -16, -6, 19, 27, -35, 3, 2, -58, 19; /M: SY='D'; M= -16, 3, 51, -1, -59, -24, -47, -21, -17, -18, 43, -7, -58, 16, -13, 20, -9, -19, -72, -65; /M: SY='Q'; M= 7, -56, 5, 12, 7, -58, -36, -21, -5, -8, -33, -12, 0, 35, -12, 0, -12, -19, -49, 29; /I: I=-24; MD=-61; /M: SY='Y'; M= -62, -86, 0, -22, -45, 13, -60, -63, -35, -13, 17, -61, -88, -15, -70, -29, -64, -68, -62, 29; D=-24; /I: I=-24; MI=0; MD=-61; IM=0; DM=-61; /M: SY='L'; M= -43, -58, 13, 21, 22, -68, -52, -4, 6, 26, -18, -14, -65, -4, -43, -5, -11, -4, -64, -35; /M: SY='K'; M= -2, -67, -28, 34, -70, -55, 7, -58, 47, -25, -42, 23, -13, 32, 2, -10, -35, -30, -82, -61; /M: SY='E'; M= 19, 6, 20, 48, -71, -49, 1, -26, -21, -60, -51, -33, 17, -21, -44, 34, -5, -8, -81, -62; /M: SY='K'; M= -41, -69, 3, 20, -20, -65, -43, -44, 37, 7, -32, -41, 35, 15, 13, -5, -40, -26, -68, -8; /M: SY='W'; M= -58, -60, -83, -65, 42, -86, -37, -28, -53, 27, -17, -70, -80, 7, 3, -61, -55, -17, 95, 63; /M: SY='E'; M= -31, 32, 37, 41, -72, -54, -46, -67, 29, -30, -52, -28, 16, -18, 5, 30, -28, -59, -88, -69; /I: I=-11; MD=-28; /M: SY='N'; M= -2, -69, -58, -56, -76, -66, -60, -64, 6, -9, -50, 24, -75, -45, 5, -7, 0, -60, -95, -79; D=-11; /I: I=-11; MD=-28; /M: SY='R'; M= -68, -95, -3, 4, -67, -91, 7, -60, -17, -30, -57, -58, -84, 7, 29, -64, -65, -20, -81, -7; D=-11; /I: I=-11; MD=-28; /M: SY='E'; M= -28, -83, -69, -5, -17, -34, -71, -29, -33, -5, -49, -23, -90, -58, -21, -29, -64, -58, -82, -11; D=-11; /I: I=-11; MI=0; MD=-28; IM=0; DM=-28; /M: SY='P'; M= -68, -84, -73, -5, -19, -99, -85, -47, -81, -1, -46, -31, 17, -66, -87, -35, -30, -12, -95, -71; D=-11; /I: I=-11; DM=-28; /M: SY='W'; M= -50, 9, -59, 13, -71, -84, -67, -3, -8, -33, -46, -63, -78, -5, -10, 3, -46, 2, 15, -71; D=-11; /I: I=-11; DM=-28; /M: SY='Q'; M= 0, -65, 19, -1, -81, -55, -35, -77, -21, -74, -53, -8, 13, 54, 33, 12, 15, -61, -74, -70; D=-11; /I: I=-11; DM=-28; /M: SY='S'; M= -13, -54, -14, 5, 8, -18, -49, -6, 23, 8, -28, -11, -58, -3, -33, 33, -5, -34, -69, -42; /M: SY='F'; M= 0, -62, -34, 48, 50, -66, 15, -44, 7, 5, -30, -49, -61, 6, -38, -36, -21, -44, -48, 6; /M: SY='W'; M= -44, -54, -60, -47, 10, -72, -49, -10, 6, 14, -20, 2, -69, 17, -42, -22, 13, 13, 90, 3; /M: SY='W'; M= -9, -56, -12, 16, -11, -67, 4, 4, 9, 23, 8, -48, -62, 16, -39, -17, -1, -12, 32, -42; /M: SY='L'; M= -10, -57, -52, -13, -45, -20, 0, -9, -39, 30, 15, 15, 17, 12, 9, -39, -15, -4, -70, -56; /M: SY='C'; M= 28, 87, -19, -15, -58, -51, -54, -47, -6, -10, -37, -42, -9, 16, -45, 21, 12, -38, -72, -61; /M: SY='F'; M= -6, -49, -23, 1, 33, -8, -53, 23, -24, 4, -24, -49, -64, -42, -55, 18, 11, -20, -52, 9; /M: SY='D'; M= -42, -61, 25, 21, -20, -22, -1, -14, -15, 24, 2, 17, -65, -31, -17, 1, -11, -17, -75, -51; /M: SY='Q'; M= -42, -76, 7, 21, -60, -64, -25, -40, 26, -40, 0, -32, -2, 77, 34, -35, -16, -55, -60, -12; /M: SY='Q'; M= -1, -57, -44, 6, -12, -60, 27, -36, -13, 29, -20, 7, -60, 42, -39, 7, -34, -39, -55, 16; /M: SY='M'; M= -23, -51, -67, -17, 8, -75, -4, 16, -19, 27, 30, -60, -14, -40, 6, -22, 0, 17, -62, -39; /M: SY='D'; M= -2, -64, 43, -19, -65, -52, 31, -38, 28, -16, -43, 8, -14, 17, -5, 9, -11, -51, -81, -55; /M: SY='E'; M= -1, -60, 11, 53, -60, -57, -44, -46, 9, 8, -32, -35, -54, 5, -10, 8, 25, -42, -81, -65; /M: SY='Q'; M= -36, 14, -51, -11, -4, -65, -41, -31, -14, 30, -17, -15, 17, 54, -13, 15, -33, -22, -63, -47; /M: SY='R'; M= 0, -53, -58, -17, 2, -61, -6, -11, 9, 6, 9, -47, -60, -6, 35, 18, -29, 14, -64, -42; /M: SY='P'; M= -25, -74, -8, 41, -17, -1, -42, -36, 29, -43, -48, 7, 47, 19, 7, -33, -18, -55, -78, -58; /M: SY='E'; M= -22, 12, -27, 51, -12, -24, 5, -44, -2, 10, 3, 6, -60, 2, -17, -11, -1, -44, -65, -4; /M: SY='Q'; M= 0, -56, -21, -6, -21, 0, -42, -5, -11, -25, 8, -15, 14, 41, 15, 1, 4, -4, -66, -54; /M: SY='S'; M= -23, -56, -7, 19, -68, 13, -41, -62, 14, -23, -45, -4, -53, 18, 9, 47, 18, -54, -78, -65; /M: SY='F'; M= -22, 9, 1, 4, 29, -7, -49, 17, -11, 4, -26, 5, -70, -41, -52, -23, -18, -12, -49, 26; /M: SY='W'; M= 7, -49, -50, -15, -7, -55, 4, -18, -10, 24, 11, 2, -60, -4, -44, 27, -5, -33, 27, -2; /M: SY='C'; M= -20, 34, 26, 1, -17, 19, 15, -69, -34, -45, -56, 30, 19, -32, 20, 0, -11, -62, -67, -4; /M: SY='P'; M= -9, 7, 9, 9, 8, -62, 9, -44, 7, -33, -4, -9, 25, 1, 7, -30, 15, -13, -52, 22; /M: SY='P'; M= -18, -66, 6, -37, -39, -4, -45, -43, -5, -11, -40, -50, 81, 10, -48, -39, -19, -10, -53, 33; /I: I=-11; MD=-28; /M: SY='S'; M= 12, -51, -53, 5, -19, -61, -55, -2, -7, -5, -30, -51, -60, -1, 3, 18, -6, 15, -73, -55; D=-11; /I: I=-11; MD=-28; /M: SY='W'; M= -51, -85, -13, -2, -93, -3, -67, -86, -63, -96, -80, -20, -82, 10, -71, 18, -48, -43, 33, -79; D=-11; /I: I=-11; MI=0; MD=-28; IM=0; DM=-28; /M: SY='Y'; M= -58, -79, -19, 24, -6, -84, 7, -33, -31, -10, -48, -57, -80, -9, -20, -9, -54, -57, -48, 49; D=-11; /I: I=-11; DM=-28; /M: SY='P'; M= -25, 10, -15, 12, -16, -7, -1, -83, -51, -81, -70, 0, 60, -42, -21, -20, -18, -73, -73, -3; D=-11; /I: I=-11; DM=-28; /M: SY='P'; M= -24, -77, 27, 7, -91, -2, -53, -79, -16, -85, -69, -11, 28, 10, 0, 8, -12, -45, -92, -82; D=-11; /I: I=-11; DM=-28; /M: SY='P'; M= -10, -55, -52, -9, -61, 20, -52, -8, -16, -15, -32, -46, 41, 13, 4, -11, 30, 12, -74, -66; /M: SY='W'; M= -51, -57, -21, -67, -23, -81, -66, -5, -72, 56, -2, -72, 17, -56, -69, -26, -21, -24, 80, -1; /M: SY='W'; M= 0, -56, -85, -69, 5, -74, -55, -30, -31, 20, -20, -76, -73, -15, -58, -52, -50, -5, 130, 32; /M: SY='P'; M= 32, -52, -49, -48, 9, -24, -54, -50, -49, -31, 3, 23, 81, -42, -57, -9, -35, -26, -65, -46; /M: SY='F'; M= -50, -47, -80, -73, 56, -83, -63, 20, -67, 26, 50, -28, -76, -55, -68, -48, 14, 10, -43, -12; /M: SY='D'; M= -20, -78, 61, 54, -79, -16, -37, -66, 0, -49, -52, -22, -54, 49, -35, -30, -12, -33, -82, -71; /M: SY='E'; M= 6, 14, -3, 40, -10, -27, -59, 10, -50, -23, -30, -51, -61, -33, -58, -3, -30, 39, 31, -45; /M: SY='L'; M= -57, -52,-100, -82, 4, -92, -68, 18, -73, 60, 60, -87, -79, -56, -70, -69, -48, -11, -53, 1; /M: SY='V'; M= 32, -39, -77, -59, -35, -61, -64, 8, -61, 21, -14, -67, -61, -54, -65, -14, -11, 49, -59, 1; /M: SY='Q'; M= -22, -71, -23, 40, -75, -4, 51, -79, 28, -75, -52, 29, -54, 51, -20, -9, 5, -65, -78, -50; /M: SY='P'; M= -15, -70, -42, -13, -81, -60, -51, -18, -42, -67, -55, 32, 106, -38, -14, -36, -44, -51, -86, -79; /M: SY='F'; M= -52, -48, -87, -79, 65, -87, -57, 33, -74, 24, -11, -76, -81, -66, -74, -25, -11, 7, -34, 31; /M: SY='E'; M= 21, -54, -13, 36, -65, -54, -44, -8, 3, -31, -38, -15, -54, 2, 30, 3, -12, 13, -77, -64; /M: SY='K'; M= -33, -49, -59, -45, -46, -64, -57, 11, 26, 17, 12, -13, -63, -35, -7, 22, 5, 23, -75, -58; /M: SY='R'; M= -24, -82, -46, 11, -80, -18, -30, -79, 27, -72, -52, -36, -58, 25, 85, -34, -8, -67, -73, -68; /M: SY='F'; M= -32, -51, -93, -88, 100, -85, -56, -15, -76, -3, 6, -84, -85, -68, -79, -62, -57, -36, -18, 23; /M: SY='R'; M= -14, -66, -31, 30, -72, -57, -30, -33, 25, -58, -4, 17, -55, 33, 60, -24, 24, -48, -73, -64; /M: SY='Y'; M= -59, -55, -78, -75, 66, -87, -10, -44, -63, -40, -45, -61, -87, -56, -24, -51, -13, -50, 6, 111; /M: SY='H'; M= -56, -94, -50, -32, -53, -71, 132, -89, -40, -76, -63, -19, -64, -7, 3, -40, -47, -80, -69, 0; /M: SY='F'; M= -63, -52, -89, -91, 107, -21, -53, -35, -77, -21, -26, -80, -89, -71, -80, -63, -60, -45, -13, 30; /I: I=-17; MD=-42; /M: SY='M'; M= -51, 10, -3, 1, -13, -73, 22, -49, -50, -26, 57, 0, -74, -4, -22, 5, -42, -52, -62, -2; D=-17; /I: I=-17; MI=0; MD=-42; IM=0; DM=-42; /M: SY='G'; M= -20, -74, -22, -59, -96, 50, -75, -95, -66, -95, -81, -49, 24, -62, -73, 20, 4, -79, -97, -93; D=-17; /I: I=-17; DM=-42; /M: SY='N'; M= -24, -74, 20, -9, -93, -62, -4, -89, -6, -92, -74, 38, -73, -4, -48, -1, 16, -74, -99, -75; D=-17; /I: I=-17; DM=-42; /M: SY='P'; M= -59, -99, -68, -41, -94, -81, -54, -91, 40, -82, -15, -57, 44, 18, 37, -57, -61, -84, -95, -88; D=-17; /I: I=-17; DM=-42; /M: SY='Q'; M= -29, -82, 24, 8, -91, -23, -46, -87, 10, -84, -60, -39, 14, 53, -38, -36, 13, -73, -87, -82; D=-17; /I: I=-17; DM=-42; /M: SY='T'; M= 5, -38, -43, -11, -19, -47, 1, -42, -16, -15, -33, -29, -50, -31, -42, 41, 76, -31, -67, -47; /M: SY='N'; M= -18, -56, -14, -8, -77, -41, -28, -36, 26, -75, -58, 86, -6, -21, -25, 17, -23, -58, -89, -62; /M: SY='W'; M= -35, -65, 21, -29, -55, -16, -41, -59, 18, -67, -49, -6, -8, -3, 49, 24, -31, -17, 95, -38; /M: SY='L'; M= 7, -44, -64, -47, -40, -59, -56, 24, -51, 33, -11, -53, 21, 11, -55, 25, 9, -3, -70, -55; /M: SY='D'; M= -28, -63, 59, 40, -73, -2, 11, -62, -32, -67, -7, -18, -53, 6, -6, 40, -5, -31, -80, -62; /M: SY='K'; M= -39, 15, -16, -18, -67, -60, -40, -34, 75, -34, 1, -32, -53, 41, 15, -15, -38, -52, -82, -65; /M: SY='P'; M= -37, -73, -52, -14, -18, -23, -57, -21, -48, -57, -4, -23, 113, -8, -59, -42, -48, -51, -74, -64; /M: SY='E'; M= -20, -89, 4, 99, -90, -62, -32, -82, -5, -82, -62, -33, 3, 21, -31, -27, -38, -62, -95, -76; /M: SY='W'; M= -55, -61, -77, -62, 42, -78, 2, -57, -58, -29, -33, -63, -76, 12, -10, -49, 8, -53, 142, 36; /M: SY='Y'; M= 14, 12, -75, -67, 58, -67, -32, 12, -65, -13, -29, -63, -70, -56, -66, -4, -38, -9, -16, 79; /M: SY='F'; M= -57, 16, -91, -85, 86, -88, -56, 2, -74, 26, 14, -79, -83, -65, -75, -58, -15, -25, -25, 25; /M: SY='A'; M= 45, -46, 12, 41, -72, -40, 7, -63, -15, -66, -52, -8, -2, 2, -39, 20, 29, -43, -76, -60; /M: SY='W'; M= -53, 22, -60, -43, 55, -75, 41, -35, -47, 22, -19, 6, -72, 44, -48, -49, -48, -42, 60, 29; /M: SY='I'; M= -4, -42, -89, -73, 10, -83, -65, 55, -72, 21, -6, -80, -74, -65, -73, -52, -37, 39, -52, 21; /M: SY='L'; M= -50, -60, -42, 29, 13, -74, 8, -10, 0, 38, 7, 0, -69, -28, -13, -45, -13, -30, -48, 33; /M: SY='K'; M= -33, -62, 34, 6, -62, -13, -36, -71, 46, -69, -8, 38, -55, 6, -18, 21, 10, -61, -74, -8; /M: SY='W'; M= -52, -52, -85, -67, 45, -86, -51, 11, -26, 11, 13, -74, -78, -7, -58, -60, -47, 22, 105, 41; /M: SY='L'; M= -10, 17, -68, -18, -6, -74, -67, 32, -62, 38, -5, -62, -68, -51, -64, -33, 35, 17, -66, -45; /M: SY='D'; M= -21, -66, 44, -2, -58, -21, 28, -30, 12, -67, -53, 12, -56, 24, 36, 18, -7, -54, -67, -1; /M: SY='E'; M= -17, -68, 54, 58, -18, -51, -40, -35, 15, -69, -58, 9, -53, -13, -9, 14, -8, -54, -82, -55; /M: SY='N'; M= -53, -59, -30, -40, 38, -57, 56, -59, -42, -31, -44, 68, -73, 13, -42, -31, -5, -59, 32, 50; /M: SY='R'; M= -8, -58, -14, 15, -48, -8, -2, -24, -31, 26, 8, -47, 5, 2, 30, -14, -13, 6, -70, -57; /M: SY='D'; M= -21, -60, 49, 22, -34, 9, -37, -24, -43, -33, 7, -9, -9, -1, -52, 3, 8, -12, -49, 41; /M: SY='F'; M= -46, -54, -58, -19, 68, 6, -45, -14, -11, 12, -23, -13, -72, -10, -51, -20, 2, -36, -32, 33; /M: SY='C'; M= -43, 50, -81, -71, 34, -85, -63, 9, -34, 33, 14, -23, -77, -58, -65, -54, -38, 42, -48, 8; /M: SY='D'; M= -9, 14, 43, 12, -60, -1, -44, -3, -11, -9, 3, -9, -59, 15, 29, -11, -11, -36, -75, -64; /M: SY='E'; M= -12, -56, 31, 33, -15, -16, 6, -15, -42, 4, -31, 7, -59, -3, -49, 18, -5, -5, -64, -2; /M: SY='W'; M= -43, -50, -51, -9, -10, -71, 24, 28, -7, 1, 10, 15, -69, -36, -16, -22, 6, 25, 38, 5; /M: SY='F'; M= -25, 10, -24, -17, 37, -82, -60, 27, -60, 35, 12, -69, -74, -52, -22, -54, -42, 20, -48, 8; /M: SY='Q'; M= -5, -68, 33, 5, -48, 8, 8, -35, -21, -32, 2, -28, -53, 82, -6, -31, -39, -52, -50, 16; /M: SY='P'; M= -6, -67, 51, -7, -73, -56, -5, -29, -42, -38, -51, -35, 87, -36, -10, -13, -10, -23, -83, -69; /M: SY='I'; M= -5, -46, -29, -56, -9, -22, -66, 35, -24, 24, -11, -61, -10, -51, -15, -38, 12, 28, -68, -47; /M: SY='F'; M= -26, 8, -82, -73, 54, -24, -67, 31, -70, 26, -10, -72, -10, -63, -72, -25, -11, 18, -47, -13; /I: I=-10; MD=-25; /M: SY='D'; M= 14, 8, 45, 8, 9, -24, -55, -45, 13, -21, -44, -33, -57, -32, -41, 14, -32, -10, -71, -44; D=-10; /I: I=-10; MD=-25; /M: SY='E'; M= 3, -71, 37, 39, -79, -56, -44, -62, 25, -48, -53, -5, 18, 21, -8, -14, -39, -25, -87, -73; D=-10; /I: I=-10; MD=-25; /M: SY='A'; M= 32, 3, -12, -15, -27, -61, 1, -66, -13, -43, -14, -56, -64, -4, -54, -31, 4, -54, -81, -61; D=-10; /I: I=-10; MD=-25; /M: SY='F'; M= -39, -87, -32, -15, 15, 9, -10, -79, -62, -67, 11, -66, -88, -57, -5, -12, -62, -78, -77, -48; D=-10; /I: I=-10; MI=0; MD=-25; IM=0; DM=-25; /M: SY='E'; M= 7, -73, -30, 11, -86, -80, -84, 1, -72, -63, -59, -77, 1, -58, -82, -26, -55, -8,-105, -90; D=-10; /I: I=-10; DM=-25; /M: SY='W'; M= -23, -83, -91, -82, -59, 9, -88, -40, -11, -15, -51, -80, -89, -65, -66, -32, -67, -64, 94, -48; D=-10; /I: I=-10; DM=-25; /M: SY='N'; M= -47, -64, 8, 26, -72, -68, -54, 7, 9, -52, -44, 28, -70, -32, -43, -17, 9, 10, -94, -71; D=-10; /I: I=-10; DM=-25; /M: SY='G'; M= 1, -62, -59, -55, 1, 47, -48, -69, -22, -41, -56, -46, -4, -47, 5, 18, -13, -62, 21, 32; D=-10; /I: I=-10; DM=-25; /M: SY='E'; M= 3, -53, -33, 29, -47, -4, -45, -5, -19, -5, 24, 28, -3, -29, -47, 9, -30, 1, -66, -3; D=-10; /I: I=-10; DM=-25; /M: SY='M'; M= -15, -48, -27, -18, 21, -2, -50, 6, -51, -6, 45, -51, -66, -43, -18, -30, 38, 10, -44, 25; D=-10; /I: I=-10; DM=-25; /M: SY='I'; M= -33, -46, -61, -52, -31, -67, -48, 41, 0, -14, -23, -13, -67, -45, -15, 25, 1, 26, -54, 31; D=-10; /I: I=-10; DM=-25; /M: SY='T'; M= -33, -53, 22, 10, -61, -57, 0, -35, -3, -27, 23, 17, -10, 16, -39, 8, 45, 2, -73, -59; D=-10; /I: I=-10; DM=-25; /M: SY='M'; M= 33, -44, 4, -38, -19, -47, -53, -36, -41, -20, 53, -14, 20, -35, -9, 17, 25, -19, -62, -54; D=-10; /I: I=-10; MI=0; MD=-25; IM=0; DM=-25; /M: SY='H'; M= -44, -61, -65, -45, -6, -6, 68, -21, 0, 22, 12, -46, -67, 2, 16, -27, -41, 14, 31, -27; /M: SY='C'; M= -30, 40, -46, 13, -35, -61, -5, -13, -19, 31, -18, -17, -62, -4, -14, 33, -4, -14, -61, 6; /M: SY='Q'; M= 13, -63, -22, 53, -15, 22, -31, -66, -26, -33, -44, 4, -2, 58, -36, -5, -34, -55, -61, -6; /M: SY='F'; M= -52, -54, -80, -75, 86, -80, -46, -33, -69, 10, -23, -74, 47, -61, -72, -19, -51, -42, -20, 47; /M: SY='I'; M= -22, -40, -81, -67, -6, -80, -73, 56, -67, 18, 31, -68, -71, -58, -68, -21, 20, 33, -65, -44; /M: SY='R'; M= -20, 3, -34, 3, -14, -20, -33, -53, -5, -16, -40, 43, -62, -25, 49, -4, 36, -48, -62, -2; /M: SY='H'; M= 24, -56, -41, 14, -50, 21, 51, -50, 8, -4, 6, -11, -54, -23, -10, 5, -8, -45, -66, -7; /M: SY='L'; M= -45, -53, -72, -51, -6, -78, 11, 15, 18, 39, 33, -57, -68, -5, -11, -46, 5, 11, -64, -42; /M: SY='L'; M= -19, 20, -94, -76, 13, -84, -74, 25, -71, 50, 44, -82, -74, -58, -71, -57, -40, 26, -57, -37; /M: SY='P'; M= -19, -59, -43, -11, 24, -18, -45, -39, -43, -32, -2, 26, 81, 23, -51, -34, -12, 0, -59, -36; /M: SY='P'; M= -31, -52, -63, -51, -46, -22, -63, 10, 0, 24, 13, -55, 63, -43, -48, 23, -30, 10, -74, -62; /M: SY='M'; M= 1, -43, -15, -56, -31, -30, -64, 24, -62, 29, 46, -62, -66, -51, -65, -22, -8, 38, -58, -6; /M: SY='R'; M= -42, -57, -57, -9, -47, -71, -45, 14, -4, 18, 5, -14, -66, 1, 55, -19, -10, 19, -70, -58; /M: SY='E'; M= -17, -66, 16, 68, -74, -4, -2, -12, 2, -61, -49, 10, -53, 11, -13, 6, -5, -24, -86, -64; /M: SY='K'; M= -38, -68, 4, -19, -67, -60, -44, -28, 73, -33, -38, -31, -54, 22, 16, -17, -12, -3, -86, -66; /M: SY='I'; M= -9, -42, -80, -64, -36, -76, -70, 45, -59, 28, 31, -67, -68, -53, -23, -20, 12, 36, -68, -53; /M: SY='N'; M= -25, -65, 31, -1, -43, -55, 36, -32, 6, -64, -52, 42, -62, 5, 38, -14, 0, -32, -55, 31; /M: SY='E'; M= -3, -55, -1, 44, -63, -56, 6, -28, 24, -30, -36, -6, -53, 20, -28, 12, 4, 24, -78, -58; /M: SY='T'; M= -15, 24, 18, 17, -53, -54, -43, -18, -13, -19, -36, 16, -58, -28, 8, 16, 45, -2, -69, -15; /M: SY='M'; M= -39, -46, -77, -61, -10, -75, -67, 31, -12, 41, 42, -63, -69, -47, -53, 8, -10, 20, -64, -47; /M: SY='P'; M= 24, -53, 23, 11, -26, -16, -1, -34, -17, -38, -47, -7, 60, -31, -47, 13, 8, -24, -75, -55; /M: SY='C'; M= 11, 42, -9, 30, -59, -53, 30, -25, 25, -18, -2, -9, -53, 15, -28, 7, 16, -39, -75, -53; /M: SY='I'; M= -1, -48, -49, -16, -37, -24, -47, 21, 6, 12, -21, 14, -62, -36, -8, 11, -4, 13, -62, 10; /M: SY='S'; M= 12, 8, 0, -11, -16, -53, -43, -15, -12, 10, -25, -38, -55, 29, 18, 30, -4, -6, -66, -50; /M: SY='E'; M= 0, -62, 31, 41, -59, 14, 8, -67, 13, -29, -50, -26, -51, 18, -32, 34, -26, -57, -71, -9; /M: SY='D'; M= -18, -64, 44, 17, -55, -4, 26, -50, -2, -36, -1, 23, -57, 32, -9, 2, -13, -15, -66, -3; /M: SY='P'; M= -11, -63, 9, 24, -76, -20, 4, -41, -9, -69, -52, 8, 71, 28, -11, 18, 6, -54, -79, -65; /M: SY='A'; M= 41, -42, -8, 9, -66, -40, -42, -46, -33, -38, -43, 7, 8, 15, -9, 37, 19, -9, -71, -61; /M: SY='W'; M= -21, -53, -48, -24, 12, -26, 6, -3, -45, 26, -19, 32, -69, -39, 1, 6, -33, -3, 44, 6; /I: I=-8; MD=-20; /M: SY='W'; M= -52, -57, -73, -29, 34, -80, -63, -9, -65, 41, -10, -27, -79, -51, -26, -14, -47, -14, 99, -14; D=-8; /I: I=-8; MD=-20; /M: SY='S'; M= 17, 11, -11, 11, -20, -47, -52, -42, -46, -4, -1, -11, -54, -35, -53, 51, 3, -21, -72, -54; D=-8; /I: I=-8; MI=0; MD=-20; IM=0; DM=-20; /M: SY='H'; M= -45, -76, -47, -8, -17, -67, 119, -57, -16, -38, -50, -24, -62, -11, -5, -1, -38, -21, -67, -7; /M: SY='L'; M= -49, -49, -88, -76, 24, -85, -69, -4, -71, 65, 6, -76, -76, -58, -69, -51, 16, -1, -57, -32; /M: SY='I'; M= -16, -41, -80, -70, -37, -25, -76, 59, -68, 11, 35, -26, -73, -61, -71, -52, -34, 45, -70, -53; /M: SY='D'; M= -37, -65, 63, 1, 25, 14, 41, -60, -49, -63, -60, -21, -62, -35, -54, 23, -33, -30, -47, 37; /M: SY='Q'; M= -38, -80, -9, 78, -70, -64, -22, -63, -15, -14, -35, -6, -49, 80, -26, -30, -38, -56, -71, -65; /M: SY='C'; M= -5, 46, -78, -64, -36, -72, -70, 37, -63, 26, 39, -62, -67, -53, -65, -16, 26, 25, -66, -54; /M: SY='M'; M= -38, -46, -77, -57, 10, -74, -59, 18, -50, 32, 66, -62, -67, -6, -11, 8, -30, 25, -54, -39; /M: SY='A'; M= 41, -38, -51, -37, -55, -42, 4, -4, -15, -15, -31, -16, -48, -2, -43, 36, 28, 8, -70, -53; /M: SY='F'; M= -57, -49, -75, -77, 99, -80, -47, -37, -69, -25, -28, -24, -82, -62, -71, -45, 20, -42, 42, 37; /M: SY='D'; M= -47, -85, 93, 37, -87, -48, 6, -92, -35, -93, -82, 8, -56, -23, -12, 2, -37, -79, -94, -68; /M: SY='Q'; M= -18, -67, 26, 19, -74, -51, 33, -67, 42, -71, -51, 31, -53, 44, 1, 5, -12, -33, -79, -54; /M: SY='R'; M= 19, -59, -30, 34, -69, -51, 17, -35, 12, -38, -45, 18, -53, 7, 50, -5, 10, -46, -75, -57; /M: SY='M'; M= -47, -46, -94, -75, -26, -89, -75, 25, -69, 53, 61, -81, -74, -54, -68, -60, -19, 32, -62, -52; /M: SY='R'; M= -38, 8, -13, -1, -14, -62, 29, -32, 30, -38, -40, -32, -57, 48, 59, 2, -35, -28, -65, -44; /M: SY='N'; M= -30, -60, 15, 27, -68, 5, -36, -29, 11, -26, -44, 41, -56, 23, 0, 32, -24, -27, -80, -63; /M: SY='N'; M= -32, -52, -43, -14, 5, 14, 5, 3, 7, -3, 3, 24, -63, -33, -16, 23, -7, 5, -67, -40; /M: SY='Y'; M= -11, -56, -74, -67, 46, -4, 41, -33, -66, 3, -30, -59, 2, -49, -61, -47, -49, -11, 59, 77; /M: SY='H'; M= -6, -60, -14, -38, 23, 22, 52, -28, 14, -55, -48, 27, -64, -2, -34, -14, -39, -26, -40, 49; /M: SY='Y'; M= -2, -54, -17, -47, 22, -66, 34, -53, -54, -54, -53, -44, -6, -4, -53, -1, 2, -52, -4, 103; /M: SY='D'; M= -40, -65, 62, 2, -65, -21, 0, -25, -41, -12, -42, 28, 30, 14, -49, -1, 5, -22, -81, -62; /M: SY='G'; M= 7, -61, -54, -48, -68, 64, -59, -29, -18, -19, -43, -45, 52, -6, -15, -11, -15, -20, -77, -74; /M: SY='G'; M= -14, 7, 3, 13, -9, 39, -41, -24, -20, -22, -41, -15, -4, -5, -50, -1, 4, -9, -48, 39; /I: I=-10; MD=-25; /M: SY='D'; M= -56, -66, 17, -8, 8, -80, -60, -9, -29, 6, -32, -15, -21, -50, -28, -47, 11, -7, -66, 1; D=-10; /I: I=-10; MD=-25; /M: SY='P'; M= 12, -59, -13, -21, -64, -4, 1, -28, -28, -39, -52, -17, 18, -45, -57, 11, 6, -11, -78, -18; D=-10; /I: I=-10; MD=-25; /M: SY='N'; M= -3, -75, 5, 3, -22, -70, -55, -61, -19, -28, -55, 10, 2, -6, -17, -44, -26, -32, -77, -11; D=-10; /I: I=-10; MD=-25; /M: SY='Y'; M= -65, -75, -7, -29, -10, -96, -71, -11, -84, 7, -38, -74, -94, -71, -88, -15, -58, -7, -68, 18; D=-10; /I: I=-10; MI=0; MD=-25; IM=0; DM=-25; /M: SY='W'; M= -30, -95, -22, -15, -81, 20, -72,-110, -28,-101, -79, -63, -85, 7, -24, -26, -66, -94, 79, -61; D=-10; /I: I=-10; DM=-25; /M: SY='W'; M= -36, -83, -87, -75, -47, 6, -72, -82, -37, -52, -10, -75, -89, -8, -70, -31, -31, -76, 109, 2; D=-10; /I: I=-10; DM=-25; /M: SY='G'; M= -55, -87, -19, 1, -77, 32, -74, -18, 7, -13, -49, -60, -10, -47, -13, -57, -62, -34,-100, -87; D=-10; /I: I=-10; DM=-25; /M: SY='G'; M= -21, -58, -49, -49, -60, 67, -58, -51, -17, -8, -43, -37, -4, -44, -16, 40, -27, -23, 32, -61; /M: SY='L'; M= -38, 37, -73, -65, -28, -77, -61, 11, -64, 41, 12, -19, -8, -54, -65, -19, 20, 29, -59, 2; /M: SY='V'; M= -2, -44, -11, -49, -12, 27, -60, 0, -57, 1, 22, -47, -62, -49, -61, 11, 18, 37, -59, -11; /M: SY='W'; M= -5, -54, 32, -5, -59, 21, 26, -30, -17, -37, -49, -26, -54, -30, -9, 49, -20, -25, 54, -45; /M: SY='V'; M= -19, -47, -48, 33, -8, -77, -62, 29, -55, 29, -9, -63, -66, -38, -61, -24, -8, 40, -69, -47; /M: SY='V'; M= -47, -46, -90, -73, 34, -90, -66, 30, -28, 33, 14, -80, -77, -59, -64, -61, -40, 42, 35, 7; /M: SY='C'; M= -34, 66, -21, -55, -6, -66, 2, -8, -61, 42, -11, -16, -11, -49, -62, 21, -7, -10, -66, -43; /M: SY='E'; M= -18, 12, 37, 47, -73, -5, 27, -54, -10, -66, -51, -4, -55, 22, 18, -6, 11, -12, -78, -58; /M: SY='Q'; M= -20, -75, 24, 42, -76, -7, 7, -73, 23, -42, -48, 11, 29, 47, 11, -29, -14, -63, -79, -64; /M: SY='P'; M= 9, -58, 30, -21, -64, -53, 29, -9, 8, -33, -40, 8, 44, 34, -35, 0, -10, -10, -75, -54; /I: I=-20; MD=-50; /M: SY='W'; M= -53, 33, 42, 6, -54, 3, 57, -35, -22, -72, -61, -9, -72, -33, -22, -45, -51, -33, 70, -2; D=-20; /I: I=-20; MD=-50; /M: SY='W'; M= -79, -93, -68, 8, -43, -99, -6,-100, -85, -93, -69, -35, -97, -53, -78, -70, -28, -86, 125, 9; D=-20; /I: I=-20; MI=0; MD=-50; IM=0; DM=-50; /M: SY='F'; M= -2, -53, -89, -77, 66, -79, 6, -20, -73, 35, -13, -78, -78, -60, -72, -54, -51, -7, -37, 19; D=-20; /I: I=-20; DM=-50; /M: SY='E'; M= -35, -69, 33, 62, -72, 0, 5, -48, -11, -38, -48, 8, -56, 7, 8, 3, -13, -3, -83, -63; /M: SY='R'; M= 6, -56, -47, -36, -63, -55, -41, -11, 34, -30, 0, 24, -3, -23, 50, -26, 17, -5, -75, -62; /M: SY='W'; M= -67, -68,-100,-100, -11, -84, -69, -81,-103, -67, -37, -92, -85, -50, -68, -74, -68, -66, 172, 15; /M: SY='L'; M= 9, -47, -84, -64, 0, -30, -67, 15, -63, 55, 19, -76, -68, -10, -64, -47, -41, 7, -62, -44; /M: SY='Q'; M= -22, -67, 30, 41, -75, 0, -31, -70, 20, -43, -48, 42, -54, 48, -26, -22, 17, -59, -80, -66; /M: SY='F'; M= 22, -44, -78, -67, 43, 1, -54, 24, -65, 12, -17, -69, -67, -58, -68, -39, -38, 23, -38, 36; /M: SY='E'; M= -39, -92, 5, 100, -69, -65, -28, -81, -17, -81, -62, -33, -49, 22, -8, -29, -39, -63, -78, -3; /M: SY='K'; M= -41, 44, -48, 17, -18, -70, -46, -31, 45, 11, -25, -44, -61, 5, 37, -39, -12, 1, -72, -53; /M: SY='E'; M= -20, -80, 34, 60, -82, -55, 10, -83, 35, -79, -56, 18, -52, 45, 15, -29, -38, -68, -84, -63; /M: SY='F'; M= -44, -53, 24, -45, 61, -68, 14, -13, -61, 22, 5, -45, -71, -48, -63, 14, -37, -17, -34, 34; /M: SY='A'; M= 71, 20, -55, -39, -65, -31, -53, -47, -38, -54, -45, -44, -39, -34, -13, 19, 28, -15, -67, -60; /M: SY='W'; M= -40, -53, -52, -16, -2, -66, -42, 1, -19, 25, -17, 13, -68, -5, 11, 6, 1, -4, 60, 23; /M: SY='E'; M= 13, -64, 38, 48, -75, -50, 5, -61, 31, -69, -52, -27, -49, 23, 8, 3, -7, -23, -81, -63; /M: SY='R'; M= -41, 14, -46, -20, -77, -21, -28, -79, 48, -71, -47, -6, -1, 54, 70, -36, -42, -69, -72, -66; /M: SY='Y'; M= -21, -49, -85, -75, 65, -79, -39, -18, -68, 32, 38, -72, -77, -55, -68, -28, -46, -13, -19, 66; /M: SY='E'; M= -38, -70, 22, 46, -69, -55, 25, -38, 36, -34, 0, 27, 0, 27, -21, 4, -33, -54, -82, -58; /M: SY='S'; M= 6, -52, 11, 28, -54, 3, -41, -28, 14, -38, -47, 10, -53, -23, -10, 37, 11, -24, -68, 0; /M: SY='I'; M= -44, -50, -14, 41, -41, -81, -63, 57, -53, 10, 26, -59, -68, -35, -60, -16, -35, 18, -77, -56; /M: SY='M'; M= -21, -46, -70, -18, -27, -76, -60, 28, -26, 28, 59, -63, -67, -42, -55, -40, 23, 14, 44, 4; /M: SY='E'; M= -17, 13, -9, 36, -53, -3, -39, -5, 25, -23, -40, 26, -58, 0, -2, 1, 5, -38, -71, -3; /M: SY='N'; M= 15, -51, 21, 22, -16, -13, 3, -65, -13, -46, -53, 42, -3, -24, -40, 34, 14, -52, -74, -48; /M: SY='P'; M= 10, -61, -5, 42, -75, -2, -44, -68, -30, -40, -52, -38, 68, 7, 6, 26, -8, -55, -79, -71; /M: SY='D'; M= -9, -74, 66, 41, -78, -51, -42, -40, 22, -46, -57, 14, 0, -18, 6, -11, -37, -57, -91, -70; /M: SY='A'; M= 43, 16, 15, -11, 7, -40, -45, -50, -5, -8, -40, 38, -52, -32, -43, 15, -25, -42, -66, -42; /I: I=-10; MD=-25; /M: SY='W'; M= -4, -65, -17, -24, -8, 8, -62, -61, -57, -10, -36, -61, -71, -44, 1, -27, -52, -55, 137, -10; D=-10; /I: I=-10; MD=-25; /M: SY='F'; M= -14, -55, 7, 3, 32, -61, -7, -32, -5, 6, 27, -11, 11, -33, -13, 11, -11, -10, -56, -28; D=-10; /I: I=-10; MD=-25; /M: SY='I'; M= -1, -48, -58, -52, -40, -63, -54, 35, 2, 3, 7, 14, -6, -42, -19, -2, -7, 8, 24, -5; D=-10; /I: I=-10; MD=-25; /M: SY='D'; M= -19, -64, 47, 14, -16, -57, -47, 2, 11, -54, -46, -30, -5, 15, 5, 19, -32, -19, -77, -54; D=-10; /I: I=-10; MD=-25; /M: SY='Y'; M= -17, -63, 21, 6, 13, -20, -31, -32, -54, -60, -57, -43, -70, -4, -61, 15, -40, -31, -29, 73; D=-10; /I: I=-10; MD=-25; /M: SY='D'; M= -54, -81, 42, 40, 24, -70, 4, -63, 6, -27, 2, -37, -68, 0, -43, -20, -49, -63, -70, -36; D=-10; /I: I=-10; MD=-25; /M: SY='D'; M= -67,-103, 61, -4,-108, -29, -63,-108, -25,-108, -91, -6, -6, -7, -25, -50, -22, -95,-110, -95; D=-10; /I: I=-10; MI=0; MD=-25; IM=0; DM=-25; /M: SY='F'; M= -47, -66, -62, -3, 19, -17, -63, 0, -60, 0, -33, -62, -15, 12, -66, 7, -18, -19, -70, -41; D=-10; /I: I=-10; DM=-25; /M: SY='S'; M= 21, 15, -16, -47, -21, -52, -59, -14, -55, -17, -39, 3, -8, -48, -61, 37, -5, 7, -75, -56; D=-10; /I: I=-10; DM=-25; /M: SY='T'; M= -15, -56, 37, 8, -65, 27, 0, -7, -18, -33, -41, 20, -59, -6, -46, -20, 42, -8, -79, -61; /M: SY='D'; M= -6, -56, 30, -8, -18, -56, -45, -13, -1, -32, -38, 27, 18, -31, 30, -11, -7, 20, -73, -53; /M: SY='D'; M= -38, -68, 45, 36, 14, 28, 5, -29, 1, -59, -53, -8, -61, -25, -15, -2, -17, -22, -61, 4; /M: SY='D'; M= 16, -56, 36, 34, -52, -51, -40, -22, 12, -32, 2, 9, -53, 18, -34, -7, -8, -2, -66, 0; /M: SY='T'; M= -18, -51, 4, 6, -26, -62, 7, -19, -4, -6, 34, -4, -60, 1, -41, -22, 50, -15, -42, 46; /M: SY='K'; M= -44, -74, -53, -27, -18, -64, -41, -49, 71, -4, -33, -38, -57, 11, 52, -42, -43, -28, -77, -54; /M: SY='P'; M= 33, -48, -64, -51, -60, 0, -64, 19, -49, -24, -33, -62, 78, -46, -20, -11, -33, 10, -75, -66; /M: SY='P'; M= -28, -53, -45, -39, -16, -56, -50, -59, 6, -63, -47, 4, 86, -34, -40, 8, 61, -46, -73, -56; /M: SY='Y'; M= -23, -60, -15, 7, 27, -21, -34, -41, 34, 2, -32, -11, -63, 2, -8, -15, -15, -25, -37, 53; /M: SY='C'; M= 9, 73, -55, -13, -51, 15, -63, 14, -54, -11, 6, -45, -59, -45, -60, 35, -3, 12, -71, -59; /M: SY='A'; M= 60, -35, -47, 4, -44, -37, -47, -37, -43, -16, -37, -45, -44, -33, -50, 28, 13, -2, -56, 13; /M: SY='D'; M= -18, -58, 43, 37, -34, -60, -36, -5, -38, -16, -36, -6, -60, 8, -16, -2, -8, 13, -51, 37; /M: SY='R'; M= 5, -56, -15, -34, -10, -2, -32, -40, -4, -43, 30, 2, -59, 16, 49, 0, -11, -6, -46, 30; /M: SY='F'; M= -24, -44, -88, -74, 63, -86, -52, 7, -72, 15, -13, -78, -78, -65, -73, -55, -39, 48, -29, 45; /M: SY='M'; M= -21, -51, -46, 15, -47, -26, -49, 19, -18, 13, 27, 2, -63, -3, 17, -32, 25, 13, -70, -58; /M: SY='D'; M= -5, -63, 49, 7, -51, -52, -37, -66, 23, -41, -51, 14, 30, 14, -9, -7, 17, -56, -63, 15; /M: SY='L'; M= -51, -54, -72, -14, 21, -82, -59, 0, -46, 54, 45, -68, -72, -42, 14, -51, 2, -19, -55, -34; /M: SY='L'; M= -9, -48, -62, -1, 19, -72, -51, 14, -55, 41, 18, -61, -67, -2, -58, -15, 7, -4, -48, 20; /M: SY='W'; M= -36, -70, 34, 49, -63, -56, 6, -72, 18, -46, -52, -6, 17, -15, 7, 12, 5, -60, 74, -45; /M: SY='S'; M= 22, 12, -39, -12, -16, -21, -44, -15, -39, -9, -32, 30, -54, -3, -18, 31, 29, -4, -68, -49; /M: SY='M'; M= -17, -46, -5, -21, 22, -77, -65, 34, -55, 16, 41, -62, -69, -48, -17, -47, -10, 37, -56, -33; /M: SY='T'; M= -31, -41, -49, -48, 24, -61, -44, 15, -26, -34, -28, 18, -63, -43, -50, 7, 65, 13, -48, 22; /I: I=-28; MD=-71; /M: SY='D'; M= -35, -63, 62, 40, -20, -54, -45, -17, -36, -34, -48, -22, -57, 1, -13, 24, 20, -44, -79, -56; D=-28; /I: I=-28; MI=-71; MD=-71; IM=-71; DM=-71; /M: SY='R'; M= -20, 15, 2, -26, -68, -63, 62, -63, -13, -44, -48, -33, 16, 34, 64, -10, -39, -33, -70, -45; D=-28; /I: I=-28; DM=-71; /M: SY='Y'; M= -6, 37, -72, -71, 33, 28, 8, -39, -67, -7, -38, -57, -76, -55, -65, -43, -49, -22, 46, 88; /M: SY='Q'; M= -38, 3, -39, 23, -58, -21, 25, -53, 28, -40, -41, -35, -1, 52, 50, -15, -38, -14, -63, -7; /M: SY='T'; M= 5, -55, -10, -33, -54, 7, 27, -67, -13, -68, -52, 22, 31, 0, 18, 15, 36, -53, 33, 3; /M: SY='L'; M= -24, -50, -90, -77, 14, -81, -66, 5, -72, 65, 6, -80, -75, -59, -69, -23, -44, -1, -55, -2; /M: SY='P'; M= -16, -62, -37, 10, -22, -53, -43, -67, 10, -39, -50, 14, 80, -25, 21, 27, -8, -59, -76, -58; /M: SY='S'; M= -1, -49, -13, -32, -11, -17, 6, 4, -10, -8, -32, -8, -55, 16, 23, 46, -2, -32, -67, -44; /M: SY='V'; M= -3, -48, -64, -12, 31, -24, -54, 10, -7, 10, 7, -62, -12, 11, -49, -44, -36, 39, -49, 3; /M: SY='S'; M= -27, 8, 33, -24, -61, -3, -47, -53, 34, -3, -39, 0, -55, -27, -1, 38, 16, -49, -81, -63; /M: SY='Y'; M= -43, 48, -58, -12, 18, -74, 46, -39, -44, 1, -30, -47, 14, 35, -17, -18, -12, -23, 47, 59; /M: SY='Q'; M= -33, -73, -43, -12, -75, -56, -23, -78, 46, -69, -43, -28, -51, 72, 62, 16, -31, -67, -67, -63; /M: SY='L'; M= -18, -48, -67, -58, -4, -20, -60, 18, -59, 51, -3, -21, -67, -10, -60, 17, -9, -15, -66, -45; /M: SY='Q'; M= -20, -63, -51, -25, -6, -21, -27, -2, 20, -47, -34, -9, -59, 57, 49, -35, -11, -8, -48, 26; /M: SY='F'; M= -60, -52, -26, -75, 96, -84, -40, -15, -73, -10, -26, -69, -86, -65, -75, -31, -54, -38, -11, 63; /M: SY='L'; M= -25, -48, -66, -23, -4, -78, -63, 14, -58, 45, 15, 0, -73, -49, -24, -52, -39, 34, 32, -40; /M: SY='N'; M= -19, -53, 8, -11, -13, -56, -40, 27, -29, -11, -29, 39, -64, 0, 33, 14, -7, -22, -71, -48; /M: SY='D'; M= -18, -55, 37, -27, 4, -25, -46, -31, -2, 11, -28, 19, -61, 1, -5, 24, -27, 3, -67, -44; /M: SY='Q'; M= -33, -47, -52, -4, -15, -23, -45, 45, -40, -14, -17, -45, -61, 52, -46, 10, 25, 14, -65, -47; /M: SY='Q'; M= 11, -54, -41, 3, -60, -20, -27, -42, -5, -9, -28, -33, -48, 81, -2, 27, -24, -8, -61, -58; /M: SY='L'; M= 3, -49, 3, 4, -40, -63, -58, 26, -25, 34, 12, 5, -64, -39, -53, -17, 0, -3, -74, -56; /I: I=-30; MD=-77; /M: SY='P'; M= 3, -62, -27, -43, -58, -66, -55, -40, 14, -19, -41, -54, 56, -6, 3, -35, 11, 2, -72, -12; D=-30; /I: I=-30; MI=-77; IM=-77; DM=-77; /M: SY='I'; M= -46, -45, -85, -73, 34, -85, -60, 45, -70, 37, 19, -74, -8, -60, -70, -27, -10, 18, -45, 22; /M: SY='L'; M= -22, -51, -72, -25, 24, -26, -61, 18, -23, 50, 20, -67, -70, -45, 0, -21, -41, -4, -57, -32; /M: SY='D'; M= -50, -83, 79, 42, -48, -17, 41, -78, -16, -73, -7, 3, -59, -19, -43, -34, -43, -70, 55, 19; /M: SY='D'; M= -5, 6, 36, 19, -8, -53, -33, -56, 28, -17, -42, 8, -56, 17, 12, 4, -11, -52, -52, 31; /M: SY='Y'; M= -53, -51, -78, -71, 71, -83, -23, 6, -30, -6, -27, -64, -82, -54, -15, -26, -48, -15, -6, 91; /I: I=-5; MD=-14; /M: SY='H'; M= -38, -69, -25, -61, 35, -27, 66, -14, -63, 10, 6, -57, -81, -46, -21, -59, -56, -21, -53, 8; D=-5; /I: I=-5; MD=-14; /M: SY='D'; M= -68,-102, 39, 37, -76, -28, -63, -87, -61, -34, -74, -15, -83, -42, -73, -33, -64, -84, -94, -12; D=-5; /I: I=-5; MD=-14; /M: SY='E'; M= -65, 4, -62, 15, -71, -95, -3, -35, -6, -78, -68, -67, -87, -13, 9, -33, -62, -20, -85, -5; D=-5; /I: I=-5; MD=-14; /M: SY='L'; M= -78, 20,-126,-111, -53,-121,-108, 13,-105, 30, -23,-114,-108, -93,-103, -92, -72, -14, -98, -78; D=-5; /I: I=-5; MI=0; MD=-14; IM=0; DM=-14; /M: SY='S'; M= -46, -73, -16, 4, -81, -68, -60, -71, -30, -17, -57, 17, -77, -45, -22, 28, -10, -68,-101, -82; D=-5; /I: I=-5; DM=-14; /M: SY='W'; M= -29, 21, -26, -5, -60, -39, -78, -26, -38, -3, 5, -66, -81, -54, -70, -46, 20, -46, 60, -61; D=-5; /I: I=-5; DM=-14; /M: SY='R'; M= -21, -57, -45, 20, -50, -65, -41, 7, 7, 15, -20, -17, -60, 5, 54, -16, 3, 10, -71, -58; /M: SY='C'; M= -8, 53, -49, 3, -49, 30, -60, 26, -50, -9, -26, -20, -63, -43, -24, 11, 9, 16, 29, -53; /M: SY='R'; M= -19, -69, 25, -4, -69, -58, -35, -52, 14, -24, -42, -30, -58, 4, 74, 0, 3, -23, -73, -64; /M: SY='A'; M= 20, -52, -12, 16, -14, 5, -50, -40, 8, 18, -26, -13, -7, 2, -38, 5, 11, -38, -71, -52; /M: SY='V'; M= -18, -44, 0, -46, 13, -64, -50, 14, -28, 11, 12, -13, -65, -46, -55, 14, 17, 28, -49, 22; /M: SY='E'; M= -37, -70, 11, 41, -68, 13, 7, -27, 8, -22, -41, 20, 17, 36, -6, -13, -37, -16, -79, -62; /M: SY='G'; M= 0, -51, -49, -3, -19, 52, -61, -2, -29, 2, -29, -44, -60, -43, -54, 13, 16, 9, -72, -55; /M: SY='H'; M= 0, -52, 0, -14, -11, -59, 40, -13, 6, 13, 5, -12, -59, 0, -6, 2, 17, -3, -67, -40; /M: SY='N'; M= 2, -59, 21, 22, -73, -10, -38, -64, 22, -40, -49, 37, -5, 5, 7, -4, 32, -52, -81, -66; /I: I=-17; MD=-42; /M: SY='E'; M= -15, -63, 11, 44, -77, -4, -43, -63, 1, -45, -52, -32, -55, 31, -38, 29, 16, -35, -83, -71; D=-17; /I: I=-17; MD=-42; /M: SY='R'; M= -11, -67, 3, 18, -64, -59, -47, -54, 6, 6, -38, 3, -63, 4, 21, 19, -35, -53, -84, -69; D=-17; /I: I=-17; MI=0; MD=-42; IM=0; DM=-42; /M: SY='T'; M= 18, -47, -8, 0, -55, 0, 0, -7, -45, 6, -30, 16, 17, -35, -51, 24, 26, -31, -76, -57; /M: SY='G'; M= 0, 11, 6, 19, -56, 51, 5, -71, 6, -46, -56, -34, -10, -29, -13, 10, -9, -60, 35, -3; /M: SY='D'; M= -4, -55, 37, 35, -54, -25, -47, -12, -40, 10, 1, -6, -57, 17, -49, 0, 10, 4, -75, -62; /M: SY='E'; M= -8, -66, 31, 52, -75, 0, -41, -60, 7, -40, -50, -4, 35, 20, -35, 12, -11, -27, -83, -70; /M: SY='G'; M= -4, -61, 9, 36, -64, 51, -48, -28, -40, -22, -42, -12, -57, 16, -49, -8, 17, -24, 29, -61; /M: SY='L'; M= -17, -49, 5, -16, -7, -27, -62, -3, -59, 46, -7, -51, -65, -47, -62, 8, 11, 10, -67, -47; /M: SY='M'; M= -1, 18, -37, 40, -13, -63, -41, -5, -13, -9, 40, -45, -56, 36, -9, -11, 5, -4, 22, -6; /M: SY='R'; M= -39, 11, -52, -28, -61, -29, -36, 2, 25, -24, -2, -10, -5, 45, 53, -33, 14, -12, -69, -61; /M: SY='T'; M= 2, -44, -69, -56, 11, -66, 7, 8, -24, 26, -13, -54, -64, -45, -53, -13, 38, 18, 33, 2; /M: SY='C'; M= -11, 91, -17, -13, -16, 4, -63, 11, -57, -25, -1, -43, -63, -46, -63, 19, 30, -23, 35, -45; /M: SY='K'; M= 23, -57, -39, 23, -21, -3, 5, -28, 27, -20, -39, -12, 2, 5, 17, -8, -10, -22, -73, -51; /M: SY='V'; M= 9, 17, -17, -43, -47, -60, -62, 23, 20, 10, -19, -49, -9, -39, -39, 12, -4, 25, -76, -58; /M: SY='Y'; M= -25, -49, -83, -72, 39, -26, -51, 21, -30, 38, -8, -71, -76, -57, -62, -51, -12, 8, -36, 46; /M: SY='N'; M= -42, 57, -25, -14, 6, 29, 27, -31, -42, -37, -48, 71, -71, -7, -47, -26, -9, -52, -69, -37; /M: SY='S'; M= 46, 15, -12, -36, 8, -9, -2, -54, -44, -25, -45, 7, -47, -35, -49, 51, -14, -41, -63, -38; /M: SY='A'; M= 54, -35, -63, -48, -10, -43, -60, 16, -50, 0, 8, -52, -49, -42, -56, 15, 19, 4, -63, -47; /M: SY='W'; M= -4, 8, 8, 8, -14, -20, -43, -47, 29, -36, -43, 17, -57, -23, 29, 4, 12, -11, 30, -47; /M: SY='Y'; M= -51, 12, -58, 3, 53, -79, 13, -24, -21, -14, -37, -53, -76, -6, -12, -19, -47, -44, -9, 92; /M: SY='C'; M= -45, 54, -82, -25, 12, -92, -77, 48, -72, 28, 13, -79, -78, -61, -74, -58, -38, 36, -62, -37; /M: SY='E'; M= 11, -54, -22, 56, -12, -17, 8, -8, -30, -55, -45, -9, -51, 24, -17, 34, -6, -38, -64, -7; /M: SY='N'; M= -20, -61, -3, 9, 6, -51, 16, -70, -8, -66, -53, 54, -61, 20, 39, 11, 3, -61, -53, 21; /M: SY='K'; M= 21, 10, -15, -35, -12, -55, -53, -9, 34, -23, 5, -15, 1, -6, -4, -10, -12, 24, -68, -50; /M: SY='L'; M= -48, 14, -81, -71, -26, -80, -66, 10, -59, 59, 52, -18, -74, -50, -17, -26, -41, -3, -64, -53; /M: SY='Q'; M= -19, -68, -7, 35, -67, -60, 30, -28, 31, -35, -39, -32, -54, 47, 40, 1, -33, -11, -74, -54; /M: SY='E'; M= -40, -76, 47, 70, -76, -58, -33, -55, -4, -40, -49, 13, -54, 39, -8, -14, -36, -13, -84, -69; /M: SY='W'; M= -56, -61, -80, -83, 5, -27, -60, -25, -82, 9, -24, -19, -81, -51, -66, -26, -54, -44, 150, 23; /M: SY='S'; M= 22, 13, -11, -32, -63, 9, -42, -56, -37, -32, 0, 22, -49, -4, -16, 57, 19, -45, -71, -60; /M: SY='E'; M= -5, -73, 51, 54, -27, 2, 27, -82, 4, -79, -64, 31, -55, 8, -34, -11, -36, -67, -82, -52; /M: SY='D'; M= -48, -76, 68, 43, -20, -19, -42, -55, 2, -18, -5, 21, -59, 5, -12, -35, -41, -32, -79, -57; /M: SY='V'; M= -40, -50, -18, 1, 7, -77, -54, 17, 9, 17, -15, -54, -10, -4, -43, -42, 10, 35, -58, 3; /M: SY='F'; M= -29, -49, -74, -68, 73, -78, 21, 7, -66, -2, 13, -21, -13, -52, -65, -46, 1, 6, 40, 24; /M: SY='F'; M= -56, -50, -84, -78, 99, -83, -46, -29, -29, -11, -25, -73, -83, -62, -66, -24, -51, -16, -14, 45; /M: SY='I'; M= -48, -44, -94, -77, -28, -93, -79, 50, -74, 47, 23, -84, -78, -64, -73, -60, -15, 35, -70, -51; /M: SY='E'; M= -15, -73, 20, 72, -75, -59, 6, -69, -4, -44, -46, -28, -50, 56, 10, -23, 18, -55, -77, -63; /M: SY='M'; M= -51, -50, -93, -76, 20, -84, -69, 12, -68, 54, 73, -79, -74, -49, -66, -27, -42, -13, 34, -31; /M: SY='W'; M= -43, 0, -15, -45, -31, 13, 24, -65, -22, -38, -41, -7, -68, 14, -12, -33, 28, -55, 127, 14; /M: SY='E'; M= 17, -63, 38, 39, -15, 6, -40, -58, -14, -21, -2, -8, 0, 19, -2, -14, -37, -51, -64, -7; /M: SY='Q'; M= 20, -55, 28, 25, -49, -17, 26, -3, -36, -14, 0, -33, -53, 41, -42, -9, 8, -32, -62, -3; /I: I=-7; MI=0; MD=-18; IM=0; DM=-18; /M: SY='H'; M= -66, -92, -20, 0, -89, -34, 26, -64, -16, -51, -65, -1, -86, -4, 0, -56, -22, -19,-101, -73; D=-7; /I: I=-7; DM=-18; /M: SY='C'; M= -58, 43, 12, -53, -20, -85, -6, -60, -72, -76, -67, -20, -7, -18, -78, -23, 8, -17, -90, -63; D=-7; /I: I=-7; DM=-18; /M: SY='E'; M= -30, -76, 4, 15, -81, -26, -62, -57, -52, -22, -56, -18, -76, -4, -18, 14, -44, -20, -97, -83; D=-7; /I: I=-7; DM=-18; /M: SY='T'; M= -52, -77, -14, 8, -83, -74, 7, -66, -23, -44, -14, 6, -76, 11, -17, -1, 11, -37, -93, -74; D=-7; /I: I=-7; DM=-18; /M: SY='D'; M= -34, -74, 2, -19, -76, -9, -73, -9, -61, -23, -49, -59, -10, -19, -20, -11, -11, -10, -96, -83; D=-7; /I: I=-7; DM=-18; /M: SY='Y'; M= -48, -71, -63, -56, -46, -25, -49, -56, -5, -73, -63, 1, -4, -12, -19, 5, 1, -11, -59, 35; D=-7; /I: I=-7; DM=-18; /M: SY='N'; M= 2, -68, -59, -57, -67, -3, -63, -5, 10, -38, -54, 16, -9, -49, -49, -5, -46, -46, -87, -20; D=-7; /I: I=-7; DM=-18; /M: SY='S'; M= 3, -65, -13, -11, -82, -57, -52, -69, -15, -48, -60, 1, -3, 9, 6, 32, -32, -38, -88, -77; D=-7; /I: I=-7; DM=-18; /M: SY='T'; M= -36, -49, -24, -46, 26, -11, -57, 17, -17, -9, -23, -50, 17, 6, -52, -14, 34, 24, -59, -33; D=-7; /I: I=-7; DM=-18; /M: SY='N'; M= -14, 16, -40, -15, 14, -19, 3, -27, -24, -8, -34, 39, -65, -37, -18, 25, -26, 17, -59, -1; D=-7; /I: I=-7; DM=-18; /M: SY='Q'; M= 0, -63, -17, 2, -71, 22, 7, -62, 27, -40, -47, -9, -11, 32, 22, 16, -10, -33, -77, -62; D=-7; /I: I=-7; DM=-18; /M: SY='P'; M= -18, -65, 31, -2, -70, -2, 20, -31, 34, -41, -47, 13, 38, 1, -26, -10, 14, -31, -84, -60; /M: SY='E'; M= -34, -53, 9, 41, -7, -29, -46, 4, -17, -2, 6, 19, -59, -25, -45, 17, 27, -12, -72, -48; /M: SY='E'; M= 21, -52, 25, 40, -71, 3, 1, -50, -17, -64, -51, -6, -50, -21, -12, 24, 29, -9, -79, -61; /M: SY='S'; M= 3, -48, 17, 10, -56, -16, -37, -29, 8, -61, -48, 15, -51, 17, -34, 47, 23, -20, -66, -2; /M: SY='D'; M= -23, 4, 38, 22, -25, 15, 26, -64, -1, -65, -8, 22, 17, 6, 13, -15, -14, -39, -75, -51; /M: SY='W'; M= -42, -62, 11, 24, 11, 6, 8, -32, -42, -57, -47, 29, 18, 15, -48, -29, 17, -23, 45, 44; /M: SY='G'; M= 1, 36, -7, 24, -54, 42, -49, -10, -42, -24, -44, -12, -8, -34, -17, 26, -7, -39, -69, -6; /M: SY='S'; M= 2, 36, -6, -37, -52, 22, -48, -42, -16, -35, -43, -30, -54, -38, -10, 46, 41, -7, -65, -6; /M: SY='I'; M= -2, -42, -82, -67, 22, -74, -64, 45, -68, 25, -8, -71, -70, -60, -70, -3, -32, 34, -52, 9; /M: SY='F'; M= -59, -51, -89, -87, 98, -31, -52, -25, -77, -9, -23, -80, -87, -69, -78, -63, -55, -2, 42, 36; /M: SY='D'; M= -17, -76, 80, 20, -61, 21, -42, -70, -39, -26, -55, -16, -58, 26, -51, -30, -17, -64, -72, -7; /M: SY='E'; M= -19, -73, 63, 63, -83, -23, -37, -69, -13, -78, -63, 31, -54, 10, -40, -12, -9, -31, -90, -71; /M: SY='T'; M= 0, -45, -8, 25, -45, -58, -48, 0, -18, -11, 3, -39, -3, -30, -47, 15, 48, 15, -63, 0; /M: SY='I'; M= 3, -46, -72, -27, -10, -24, -68, 57, -25, 14, 14, -67, -68, -49, -15, -20, -37, 2, 31, -42; /M: SY='E'; M= 12, -57, -19, 44, -77, -12, 7, -77, 19, -76, -58, 42, -1, 9, -8, 33, -22, -60, -82, -61; /M: SY='S'; M= 14, 19, 31, -4, -20, 0, -42, -54, -13, -20, 0, -28, -52, 28, 6, 36, -3, -47, -67, -53; /M: SY='Y'; M= -56, -57, -80, -68, 32, -29, -20, -25, -64, 34, 12, -66, -82, -2, -63, -58, -53, -35, -8, 96; /M: SY='E'; M= -4, 11, 41, 48, -12, -54, -42, -58, -9, -42, -50, -29, -54, 5, 16, 17, 3, -31, -74, -53; /M: SY='K'; M= -3, -61, -33, 36, -54, -56, 26, -59, 37, -35, -3, -33, -53, 23, 9, 9, 22, -50, -66, 1; /I: I=-28; MI=0; MD=-71; IM=0; DM=-71; /M: SY='L'; M= -27, -54, -14, -18, -7, -79, -64, 21, -53, 48, 15, -64, -72, -47, 1, -49, 0, -15, 24, -44; /M: SY='Q'; M= -34, -59, -41, 7, -59, -24, -38, -20, 9, -12, -32, 9, -60, 36, 36, 12, 9, -1, 30, -55; /M: SY='T'; M= -16, -56, 1, 1, -59, -20, 29, -7, 0, -10, -33, -7, -60, 4, 18, 3, 30, -2, -76, -53; /M: SY='D'; M= -36, -63, 40, -3, -59, -18, -37, -58, 10, -34, -49, 23, -60, 2, 33, 16, 17, -30, -70, -6; /M: SY='W'; M= 22, -45, -70, -57, -33, 5, -60, 20, -27, -5, 46, -58, -60, -44, -55, 6, -31, 11, 86, 0; /M: SY='Q'; M= -20, -57, -7, 6, -6, -23, -38, -26, -9, 22, -20, -44, -61, 37, 17, -14, 3, 3, -52, 18; /M: SY='E'; M= 10, -60, 25, 45, -71, 0, -38, -57, 5, -56, 16, -8, -50, 30, 8, 12, 3, -31, -74, -67; /M: SY='M'; M= -32, -57, -9, 27, -12, -58, -38, -37, 10, 5, 38, -11, -58, 3, 22, 29, -9, -26, -56, 7; /M: SY='I'; M= -30, -46, -85, -67, -19, -87, -53, 55, -60, 29, -5, -73, -76, -15, -20, -53, -13, 20, -48, 38; /M: SY='V'; M= -31, -47, -10, 11, -43, -16, -51, 25, -24, -15, 6, -45, -62, -2, -14, 10, 16, 38, -63, -2; /M: SY='H'; M= 5, -63, 19, 31, -71, 1, 59, -66, -7, -70, -54, -26, 0, 31, 10, 22, -9, -33, -75, -47; /M: SY='R'; M= 15, -51, -17, -39, 39, -56, 3, -34, -26, -12, -32, -12, -59, -2, 45, 3, 8, 0, -51, -22; /M: SY='W'; M= -44, -45, -84, -70, 42, -86, 10, 20, -71, 25, -9, -71, -76, -57, -68, -50, 5, 44, 58, -14; /M: SY='Q'; M= -16, 13, -58, -16, -11, -66, -43, -10, 10, 20, 12, -47, -61, 26, 25, -1, 4, 6, -57, -2; /M: SY='K'; M= -37, -68, -41, 13, -14, -23, 6, -56, 49, -38, -41, -34, -56, 45, 34, -1, -11, -29, -54, 23; /M: SY='E'; M= -11, -66, 2, 59, -68, 23, 6, -34, -30, -25, -3, 5, -2, 20, -17, 6, -8, -48, -79, -63; /M: SY='F'; M= -50, -50, -82, -65, 46, -29, 6, 37, -27, 22, 10, -69, -77, -13, -59, -58, -43, 23, -43, 19; /M: SY='K'; M= -39, -78, 8, 41, -76, -61, 12, -57, 51, -67, -50, -31, -2, 8, 49, -15, -38, -12, -84, -63; /M: SY='T'; M= 20, 16, 26, 7, -63, -20, -46, -51, 0, -8, -40, 22, -2, -29, -14, 15, 28, -43, -78, -63; /M: SY='S'; M= 14, -49, -49, -10, -44, 13, -49, -18, 18, 15, -27, -39, -54, -31, -10, 36, 7, -34, -66, -5; /M: SY='C'; M= -20, 51, -72, -65, 24, 3, 5, -22, -63, 44, 10, -57, -5, -51, -63, 14, -35, -29, -57, -30; /I: I=-10; MD=-25; /M: SY='R'; M= -22, -72, 9, -27, -64, -58, -43, -34, 53, -40, -47, -34, -58, -18, 56, 7, -37, -56, 55, -54; D=-10; /I: I=-10; MD=-25; /M: SY='N'; M= 20, -57, 20, 22, -66, -48, -40, -28, -15, -11, -41, 47, 11, 4, -12, -10, -9, -44, -81, -65; D=-10; /I: I=-10; MD=-25; /M: SY='Y'; M= -63, -67, -12, -16, 19, -87, 49, -58, -65, -59, -63, -50, -86, -45, -60, -55, -58, -63, 3, 114; D=-10; /I: I=-10; MD=-25; /M: SY='F'; M= -15, -50, -75, -56, 53, -71, -56, -16, -24, 11, 25, -61, -69, -8, -1, 6, -35, 22, -46, -15; D=-10; /I: I=-10; MD=-25; /M: SY='H'; M= -43, -73, -9, -5, -74, -59, 52, -68, 46, -73, -54, 26, -60, 6, 34, -9, 7, -35, -84, -50; D=-10; /I: I=-10; MD=-25; /M: SY='E'; M= -37, -63, 13, 30, -65, -58, -42, -4, -32, -12, -40, 28, -63, 2, 19, 28, -29, -26, -84, -66; D=-10; /I: I=-10; MD=-25; /M: SY='S'; M= 19, -51, -13, -36, -56, -47, -41, -35, -31, -39, -50, 3, -6, -3, 26, 43, 10, -47, -66, -1; D=-10; /I: I=-10; MD=-25; /M: SY='W'; M= -27, -74, -2, -29, -14, -7, -46, -81, 7, -74, -51, -44, -66, 56, -38, -17, 8, -69, 85, -39; D=-10; /I: I=-10; MI=0; MD=-25; IM=0; DM=-25; /M: SY='W'; M= -80, -82, -34, -89, 14,-102, -4, -20, -99, -40, -50, -87, -20, -69, -85, -82, -77, -58, 122, 29; D=-10; /I: I=-10; DM=-25; /M: SY='T'; M= -24, 9, -21, -20, -75, -19, 0, -72, -60, -47, -61, -13, -10, -49, -64, 27, 33, -60, 30, -63; D=-10; /I: I=-10; DM=-25; /M: SY='E'; M= -46, -73, -49, 26, -78, -78, -62, -51, -29, -26, -8, -57, 14, 9, -58, 7, 10, -15, -91, -82; D=-10; /I: I=-10; DM=-25; /M: SY='W'; M= -42, -56, 17, -9, -40, -64, -51, -12, -55, -10, -35, 15, 10, -42, -58, -6, 39, -18, 92, 2; D=-10; /I: I=-10; DM=-25; /M: SY='Q'; M= -32, -58, 33, 24, -69, -17, 8, -24, -11, -57, -9, 31, -3, 38, -37, 19, 20, -15, -76, -59; /M: SY='W'; M= -17, -53, 21, 19, -46, -22, -45, 7, -18, -29, -3, -35, -1, 16, -45, 34, -5, -7, 62, -4; /M: SY='S'; M= -27, -58, 35, 10, -15, 23, -46, -17, -1, -37, -47, -28, 21, 0, -42, 36, 7, -45, -68, -11; /M: SY='S'; M= 25, -45, -5, 37, -64, -42, -43, -46, -13, -24, -42, -11, -8, 2, -40, 50, 12, -11, -76, -62; /M: SY='E'; M= 5, -59, 9, 48, -61, 0, -36, -58, -15, -40, -49, 27, 22, 21, -39, 17, -6, -25, -70, -10; /M: SY='E'; M= 8, -58, 14, 45, -58, 0, -42, -53, 2, -36, -4, -9, 13, -19, -3, 30, -25, -24, -70, -10; /M: SY='P'; M= 3, -60, -3, 15, -71, 14, -41, -35, -39, -24, -46, 56, 59, -2, -48, -25, -13, -29, -82, -68; /M: SY='L'; M= -9, -50, -66, -21, 19, -71, -61, 13, -55, 36, 13, -28, 27, -47, -19, -21, -14, 7, 29, -32; /M: SY='M'; M= 18, -48, 3, 5, -57, -2, 6, -22, -12, -23, 44, -4, -51, 17, -40, 35, 9, -21, -67, -56; /M: SY='P'; M= -3, 55, -69, -22, -40, -72, -62, 7, -55, 12, 9, -69, 67, -48, -25, -42, -38, 26, -62, -4; /M: SY='S'; M= 1, -37, -11, -31, -62, -38, -45, -48, -41, -36, -45, -24, 12, -34, -46, 74, 47, -18, -73, -59; /M: SY='S'; M= 36, -44, -45, -31, -68, 19, 4, -35, -16, -62, -49, -33, 33, 25, -40, 47, 13, -43, -71, -59; /M: SY='S'; M= -21, -56, 33, 53, -57, -1, 10, -66, -35, -73, -61, 0, -51, -18, -43, 54, 1, -35, -68, 5; /M: SY='L'; M= -1, -47, -84, -67, 34, -27, -67, 24, -65, 42, 24, -76, -14, -19, -67, -50, -42, 14, -53, -27; /I: I=-21; MI=0; MD=-53; IM=0; DM=-53; /M: SY='C'; M= 12, 53, 20, -38, -10, 11, -60, -4, -26, -2, -31, -38, -58, -45, -55, 34, -23, 7, -69, -49; /M: SY='E'; M= 28, -58, -2, 57, -69, -1, -47, -47, -35, -25, -9, -43, 51, 7, -46, -6, -33, -12, -78, -70; /M: SY='P'; M= 31, -48, -63, -18, 21, -16, -62, -3, -55, 25, 6, -65, 53, -45, -61, -14, -37, -14, -59, -37; /M: SY='L'; M= -25, -50, -79, -65, 10, -36, -63, 17, -57, 53, 16, -27, -74, -13, -17, -55, -43, 17, -61, -39; /M: SY='N'; M= 6, -54, 29, -5, -56, -53, -40, -34, -14, -1, -31, 34, -58, 26, 4, -24, 17, 4, 30, -54; /M: SY='M'; M= 8, -45, -44, -15, -38, -18, 8, -10, -47, -4, 25, 23, 5, -36, -51, 20, 25, 6, -55, 18; /M: SY='L'; M= -46, -50, -84, -70, 1, -25, -64, 9, -30, 55, 33, -72, -74, -53, -61, -28, -16, 13, -55, 3; /M: SY='R'; M= -37, -73, -17, 1, -74, -19, -34, -64, 39, -45, -45, -10, 27, 34, 60, -3, -9, -37, -75, -67; /M: SY='D'; M= -33, -57, 38, -2, -60, 1, -45, 0, -15, -17, 2, -7, -59, 1, 27, 21, 15, -9, -75, -63; /M: SY='H'; M= -47, -67, 5, -14, 7, -68, 53, -47, 11, -11, -37, -12, -1, 2, 32, -38, 4, -26, 34, 42; /M: SY='L'; M= -27, -49, -27, -64, -27, -80, -69, 18, -61, 57, 45, -69, -72, -51, -27, -50, 1, 3, -65, -53; /M: SY='D'; M= -13, 7, 38, 9, -55, 12, 1, -32, 0, -24, -46, -2, -56, 3, 3, 27, 8, -48, -69, -5; /M: SY='F'; M= -48, -54, -10, -14, 53, -76, 28, 12, -5, -9, -26, -18, -72, -7, -47, -43, 4, 8, -33, 47; /M: SY='L'; M= -8, -48, -5, -61, -3, -77, -72, 32, -68, 51, 34, -70, -72, -55, -69, -54, -42, 10, -64, -45; /M: SY='E'; M= -29, -58, -27, 41, -60, -54, 26, -9, 3, -17, 0, 8, -54, 19, 22, 38, -4, -39, -75, -53; /M: SY='R'; M= 6, -64, -13, -6, -44, -22, 5, -54, 40, -5, -37, -37, -56, 3, 48, -10, -12, -50, -59, 18; /M: SY='C'; M= 26, 46, -48, -14, -50, -48, 2, -41, -20, 8, -28, -12, -52, 13, -43, 31, 34, -34, 31, -48; /M: SY='L'; M= -53, -51, -8, -66, 7, -87, -66, 14, -72, 60, 32, -73, -77, -57, -70, -64, -46, 11, -55, 1; /M: SY='P'; M= 4, 9, -37, -34, -58, 26, 7, -73, -39, -72, -57, 29, 53, 17, -45, 44, -2, -59, -64, 0; /M: SY='P'; M= 4, -51, -16, -5, -13, -54, -39, -25, 6, -48, -4, -39, 52, 28, -37, 23, 20, -1, -53, 21; /M: SY='H'; M= 22, -55, -14, 17, -59, -51, 26, -25, 17, -2, -36, 4, -2, -24, -8, 18, -29, -23, -80, -55; /M: SY='D'; M= -4, -57, 57, -26, -54, -61, -63, 18, -56, 5, 6, -36, 33, -46, -65, -16, -10, -1, -80, -65; /M: SY='F'; M= -11, -50, -81, -69, 81, -77, -44, -2, -66, -6, 1, -72, -16, -14, -69, -26, -47, -17, -21, 51; /M: SY='T'; M= -4, -51, -56, -8, 6, -22, -43, -6, -16, 2, 7, -47, -62, -35, 26, 1, 34, -15, -49, 27; /M: SY='R'; M= 2, -62, 17, -2, -68, -21, -38, -28, 11, -25, -41, 9, -57, 27, 44, 2, -9, -16, -75, -65; /M: SY='I'; M= -46, 25, -93, -78, -8, -92, -81, 53, -77, 33, -3, -82, -80, -69, -77, -28, -37, 36, -70, -46; /M: SY='W'; M= -45, 14, -73, -60, 2, -74, -48, -5, -12, -33, -34, -59, -73, -6, -51, 1, 2, -24, 131, 44; /M: SY='R'; M= -49, 10, 11, -7, -65, -66, 5, -51, 11, -25, -43, 6, -66, 2, 73, -42, -44, -15, 33, -54; /M: SY='S'; M= 11, -58, 18, 23, -69, -19, -38, -61, 10, -54, 30, -7, -51, 32, 20, 33, -24, -52, -72, -66; /M: SY='I'; M= 18, -42, -88, -70, -12, -73, -77, 48, -70, 31, -6, -81, -69, -62, -72, -45, -37, 29, -70, -48; /M: SY='A'; M= 39, -42, -68, -53, -44, -54, -65, 8, -11, 23, 13, -20, -57, -44, -51, -14, -30, 26, -70, -58; /M: SY='E'; M= -1, -56, 1, 52, -55, -52, 5, -56, -16, -28, 0, 7, -53, -17, -11, 29, 26, -47, -69, -4; /M: SY='Q'; M= -4, -64, -36, 28, -65, 9, 4, -44, 25, -16, -37, -9, -56, 39, 12, -16, -9, -5, -76, -62; /M: SY='L'; M= -52, -50, -95, -81, -5, -92, -77, 29, -77, 56, 3, -85, -80, -64, -73, -61, -9, 17, 27, -42; /M: SY='D'; M= -3, 8, 53, 0, -66, -16, -47, -13, -44, -24, -45, 25, -58, -10, -53, 31, 1, -23, -82, -65; /M: SY='E'; M= -43, -66, 32, 35, -18, -62, 25, -26, -11, -33, -1, 19, -63, -22, 22, -12, 1, -4, -66, -4; /M: SY='Y'; M= -51, -52, -83, -69, 29, -88, 30, 18, -63, 10, 8, -65, -80, -52, -23, -54, -13, 25, 31, 64; /M: SY='I'; M= -55, -48,-100, -84, 22, -98, -79, 54, -79, 42, 21, -90, -83, -68, -78, -69, -45, 17, -62, -33; /M: SY='W'; M= -45, -54, -69, -21, 28, -78, -42, -11, -27, 6, -25, -61, -74, -46, -5, -11, -1, 15, 88, 56; /M: SY='Q'; M= -31, -63, 35, 35, -78, -48, 10, -78, -25, -78, -57, 38, -54, 42, 2, 34, 12, -64, -79, -60; /M: SY='Y'; M= -40, -67, -9, 36, -1, -7, -27, -64, 2, -60, -5, -16, -63, -1, 24, 8, -10, -59, 37, 62; /M: SY='V'; M= -44, -44, -88, -68, 18, -29, -73, 49, -69, 5, 29, -78, -77, -14, -72, -59, -37, 49, -60, -35; /M: SY='I'; M= -47, -47, -81, -72, 8, -87, -70, 41, -64, 35, -5, -24, -78, -61, -26, -52, 1, 35, -65, -40; /M: SY='M'; M= -36, 23, -52, 1, -40, -25, -50, -34, 16, 6, 53, -45, -3, 0, -37, 2, 34, -35, 29, -1; /M: SY='S'; M= -3, -49, -41, -12, -49, -4, -43, 7, -39, -15, -33, 31, -61, -2, -1, 33, -23, 15, -66, -5; /M: SY='N'; M= -15, 12, -1, 5, -58, -15, 14, -18, -35, -64, -52, 70, -65, 2, -13, 5, -9, -25, -70, -1; /I: I=-22; MI=0; MD=-57; IM=0; DM=-57; /M: SY='K'; M= -42, -73, -12, -21, -74, -24, 5, -64, 52, -64, -11, -8, -58, 46, 36, -31, 16, -35, -78, -64; D=-22; /I: I=-22; DM=-57; /M: SY='F'; M= -68, -53, -94, -93, 103, -91, -51, -33, -80, -3, -24, -85, -91, -72, -81, -68, -62, -43, -14, 39; /M: SY='S'; M= -5, -43, -4, -31, -60, -38, -35, -67, -36, -72, -58, 49, -53, -31, -16, 64, 35, -53, -69, -8; /M: SY='E'; M= 17, -59, 9, 43, -73, -19, -42, -56, 1, -39, -47, -35, -3, 18, 21, 4, 18, -25, -78, -68; /M: SY='N'; M= 20, -54, -15, -10, -17, 21, -40, -58, -11, -22, -44, 26, -57, 13, 5, 8, 18, -49, -63, -4; /M: SY='G'; M= -27, -82, -45, -21, -91, 97, -70,-105, -28, -93, -79, -38, -67, -54, -60, -32, -54, -90, -87, -92; /M: SY='A'; M= 50, -41, -67, -54, -18, 23, -66, -20, -55, 8, -26, -59, -53, -49, -61, -20, -7, 23, -67, -54; /M: SY='A'; M= 39, -52, 2, -5, -64, -47, -43, -43, 21, -12, -36, 4, -51, 30, 8, -22, -14, -9, -74, -64; /M: SY='Q'; M= -39, -77, -7, 2, -73, -64, -12, -40, -5, -60, -31, -28, -50, 107, 24, -34, -39, -60, -55, -60; /M: SY='F'; M= -60, -52, -98, -88, 72, -93, -67, 15, -78, 43, 19, -89, -85, -66, -77, -69, -53, -7, -37, 0; /M: SY='R'; M= -4, 10, -41, 29, -58, -24, 27, -17, 2, -8, 22, -41, -58, 29, 36, -12, -11, -39, -71, -55; /M: SY='F'; M= 4, 10, -63, -13, 43, -67, -1, -9, -37, -10, 7, -55, -65, 15, 20, -9, -36, 16, -44, 10; /M: SY='D'; M= -57, -98, 102, 28, -94, -50, -49, -99, -43,-101, -94, -6, -60, -30, -59, -35, -46, -86,-102, -79; /M: SY='M'; M= -11, 14, -85, -69, 44, -79, -51, 1, -58, 14, 47, -70, -73, -52, -14, -48, -15, 24, -34, 38; /M: SY='E'; M= 7, -63, 17, 49, -77, -3, -41, -68, 20, -67, -4, 22, -54, -15, 6, -20, 24, -53, -84, -70; /M: SY='A'; M= 37, -50, -11, 17, -3, -14, -3, -54, -15, -36, -47, 20, -53, 2, 1, 6, -8, -26, -62, -7; /I: I=-24; MD=-61; /M: SY='W'; M= -67, -67, -88, -89, -41, -97, -76, 26, -86, 14, 1, -8, -96, -73, -84, -34, -57, -11, 60, -4; D=-24; /I: I=-24; MI=0; MD=-61; IM=0; DM=-61; /M: SY='L'; M= -41, 11, -80, -66, -35, -82, 9, 29, -68, 38, -6, -64, -73, -56, -66, -20, 23, 33, -71, -50; /M: SY='F'; M= 6, 4, -68, -21, 45, -66, -56, 11, -57, 22, -17, -62, -67, -50, -29, 13, -33, 4, -46, 10; /M: SY='Q'; M= -15, -61, -1, 31, -75, -1, 6, -71, -30, -48, -50, 23, 33, 41, -16, 26, 18, -58, -77, -63; /M: SY='V'; M= -21, 14, -87, -68, -6, -38, -72, 8, -26, 40, 17, -75, -73, -54, -16, -54, -39, 42, -65, -48; /M: SY='F'; M= -48, -60, -26, -49, 66, -76, 4, -35, -26, 1, -28, -59, 50, 12, -23, -23, -48, -15, -36, 21; /M: SY='D'; M= -38, -63, 33, -4, -57, -5, -39, -18, -12, -33, -41, 10, -14, 29, 26, -3, 2, 4, -68, -10; /M: SY='P'; M= 5, -61, 7, 33, -59, -17, 22, -55, -36, -40, -50, -37, 54, 13, -16, 25, -29, -19, -68, -4; /M: SY='Y'; M= -17, 22, 0, -53, 18, -24, 8, -40, -61, 4, -35, 4, 32, -49, -63, -41, -17, -24, 34, 67; /M: SY='C'; M= -1, 70, -63, -47, -11, 15, -47, -10, -42, -3, -31, -46, -64, 21, 3, 3, 15, -34, -54, 16; /M: SY='W'; M= -20, 8, -44, 0, -48, -7, -49, -30, 0, 18, 25, 25, -9, -1, -16, 0, -34, -7, 34, -55; /M: SY='R'; M= -17, -64, 0, -12, -14, -56, 9, -55, 16, -63, -53, 10, -15, -24, 54, 20, -31, -17, -53, 29; /M: SY='P'; M= 3, -68, -17, -9, -19, -7, 21, -59, 6, -12, -43, -50, 84, -4, -42, -34, -18, -55, -75, -53; /M: SY='E'; M= 7, 4, 25, 61, -75, -1, -43, -68, -13, -40, -54, -30, -51, 3, -17, 29, -5, -55, -84, -70; /M: SY='G'; M= 20, -56, -37, 17, -65, 25, -46, -15, -1, -22, -5, 19, -57, -5, 16, 4, -32, -19, -77, -66; /M: SY='F'; M= 2, -50, -60, -24, 40, -24, -47, -11, -60, 23, 7, -2, -69, -48, -62, -2, -16, -19, 38, 36; /M: SY='F'; M= 3, -53, -23, -6, 59, -66, -48, -17, -42, 12, 8, -56, -67, -41, 19, -8, -19, -34, -39, 15; /M: SY='P'; M= -11, -59, -38, 17, -49, -56, 0, -14, 18, -23, -43, 7, 42, -25, 10, 25, -9, -43, -66, 11; /I: I=-11; MD=-29; /M: SY='E'; M= -26, 7, -9, 24, -26, -23, -1, -76, 4, -46, -59, -44, -3, 0, 14, 11, -20, -68, -84, -61; D=-11; /I: I=-11; MI=0; MD=-29; IM=0; DM=-29; /M: SY='I'; M= -26, -63, -17, -20, -67, -28, -72, 24, -15, -30, -38, 8, -81, -55, -62, -49, -10, 15, -95, -74; D=-11; /I: I=-11; DM=-29; /M: SY='R'; M= -10, -70, -69, -53, -54, -71, -54, -16, 23, -32, -50, -22, -73, -40, 27, 0, -45, -24, -72, 10; D=-11; /I: I=-11; DM=-29; /M: SY='D'; M= -20, -84, 47, 42, -98, -61, -53, -97, -42, -97, -82, 8, 19, -30, -15, 4, -43, -80,-103, -85; D=-11; /I: I=-11; DM=-29; /M: SY='W'; M= 8, 37, -48, 7, -56, -60, -55, -36, -51, -37, -50, -1, -13, -41, -27, 19, 18, -47, 60, -12; D=-11; /I: I=-11; DM=-29; /M: SY='C'; M= -28, 95, -30, -69, -13, -78, -10, -32, -35, 22, -26, 11, -82, -58, -68, -48, -46, -20, -75, -51; D=-11; /I: I=-11; DM=-29; /M: SY='R'; M= -51, -70, -17, 18, -2, -73, 2, 1, 22, -29, -39, 6, -69, 0, 34, -44, -19, -6, -75, -46; D=-11; /I: I=-11; DM=-29; /M: SY='L'; M= -46, -58, -63, 1, -11, -28, -61, 8, -34, 40, -12, -64, -74, -13, -60, -3, -13, -11, -66, -7; D=-11; /I: I=-11; DM=-29; /M: SY='L'; M= -9, -56, -83, -65, -33, -26, -4, -13, -62, 44, -9, -74, 15, -16, -31, -53, -47, 16, -64, -4; D=-11; /I: I=-11; DM=-29; /M: SY='N'; M= -6, -57, -17, -10, 25, -54, 9, -51, 17, -3, -36, 29, -61, 1, 16, 17, -11, -50, -62, -30; /M: SY='M'; M= -7, -54, -57, -9, -37, -65, -3, -22, -42, 28, 46, -15, -63, 29, -14, 8, -33, -3, -58, -7; /M: SY='S'; M= -35, 22, -11, 4, -63, 1, -1, -26, -3, -10, 1, 24, 13, -31, 5, 24, -30, -30, -81, -62; /M: SY='E'; M= -43, -68, 9, 33, -52, -69, -47, -17, 24, -1, -33, -43, 15, -1, 8, -17, -13, 0, -73, -9; /M: SY='G'; M= -32, -70, -11, 12, -29, 67, 3, -66, -49, -13, -49, -11, -65, -8, -56, 8, -15, -64, -79, -61; /M: SY='M'; M= -6, -50, -16, 15, -38, -60, -50, -14, -50, 10, 40, -46, 5, -35, -56, 30, 7, -5, -58, 12; /M: SY='T'; M= 24, -52, -9, 1, -69, -1, -52, -16, 6, -37, -45, 17, 19, -33, -41, -3, 27, -20, -82, -68; /M: SY='K'; M= 12, -54, -59, 1, 4, -65, -56, 1, 21, 17, 5, -58, -63, -34, -12, -19, -39, 4, -61, -1; /M: SY='L'; M= -45, -62, -20, -16, -35, -73, -49, -29, 9, 34, -18, -52, 18, -6, 9, -19, 11, -23, -61, 15; /M: SY='N'; M= -42, -63, -8, -7, -56, 33, -52, -22, -4, 21, -29, 41, -70, -39, -47, -6, -10, -43, -85, -66; /M: SY='K'; M= -5, -60, -14, -15, -13, -2, -2, -21, 23, 6, 2, 18, -64, -32, -11, -4, -38, -26, -66, -3; /M: SY='E'; M= -38, -64, -9, 39, -21, -7, -50, 10, 18, -34, -41, -13, 21, -26, -37, 6, -8, -20, -74, -8; /M: SY='T'; M= -19, -55, 36, 23, -59, -25, -55, -8, -46, -16, -37, -34, -61, -35, -25, 13, 36, 3, 29, -59; /M: SY='M'; M= 19, -50, -2, -38, -50, -56, -54, -4, -20, 15, 27, -46, -1, 14, -21, 8, 17, -27, -70, -62; /M: SY='Q'; M= -4, -56, -46, 8, -59, -30, -40, -18, 2, -5, 5, -41, -56, 53, 6, 16, 6, -6, -70, -63; /M: SY='Y'; M= 4, -59, -46, 6, -37, -24, -36, -52, 9, -4, -39, -13, -60, 2, 30, 17, 2, -49, -52, 34; /M: SY='S'; M= 24, -47, -47, 4, -16, -51, -50, 2, -9, -46, -1, -16, -7, -4, -45, 30, 12, -15, -66, -12; /M: SY='D'; M= -2, -63, 34, -27, -24, -22, 5, -32, 20, -37, -3, 32, -11, -3, -35, -1, -11, -51, -79, -54; /M: SY='D'; M= 15, -63, 31, -7, -51, 15, 6, -63, -42, -15, -49, 30, -62, 13, -23, -13, -39, -57, -64, 13; /M: SY='S'; M= -15, -56, -16, -12, 2, -55, 7, -54, 11, -55, 7, 8, -58, 27, -7, 31, 20, -29, -60, -6; /M: SY='E'; M= -26, 4, 27, 30, -17, -64, -45, -17, 20, -10, -41, 8, -64, -2, 7, -18, -42, -46, -73, -13; /M: SY='G'; M= 5, -63, -20, 3, -15, 37, -46, -59, -21, -42, -53, -15, 18, -4, -2, -12, 1, -29, -58, 19; /M: SY='K'; M= -20, 8, -15, -12, -47, 9, -1, -36, 15, -16, -40, -13, -7, -36, -17, -3, 6, 6, -65, 12; /M: SY='Q'; M= 12, -54, 4, -10, 20, -58, -47, -28, -17, -1, 1, -45, -9, 25, -48, 11, 5, -40, -55, -1; /I: I=-12; MD=-31; /M: SY='S'; M= -42, -66, 4, 3, -25, -31, -56, -31, 3, -22, 2, 8, -69, -37, -16, 23, 4, -52, -84, -63; D=-12; /I: I=-12; MD=-31; /M: SY='D'; M= -33, 6, 41, -25, -82, -71, 3, -78, -7, -27, -57, 8, -74, 41, -48, -49, -56, -75, -92, -74; D=-12; /I: I=-12; MD=-31; /M: SY='N'; M= -3, -82, -58, -1,-104, -77, -71, -50, -67, -93, -80, 10, -12, -14, -75, -24, -7, -71,-110, -97; D=-12; /I: I=-12; MI=0; MD=-31; IM=0; DM=-31; /M: SY='W'; M= -14, -78, -26, 13, 3, -33, 3, -35, -57, -67, -57, -63, 16, 22, -62, -52, -59, -33, 61, 20; D=-12; /I: I=-12; DM=-31; /M: SY='D'; M= -54, -74, 34, 10, -68, -78, -2, -24, -24, -5, -40, -44, -73, 11, -26, -44, 13, -5, -89, -70; D=-12; /I: I=-12; DM=-31; /M: SY='A'; M= 35, -54, -55, -1, -68, -2, -55, -39, -1, -20, -42, -51, -57, -9, 24, -1, -34, 6, -78, -69; /M: SY='W'; M= -7, -55, -51, -55, -56, -4, -56, -34, -53, -4, -36, 29, 16, -48, -27, 11, 4, 7, 59, -53; /M: SY='Y'; M= -8, -56, -81, -66, 3, -76, -46, -28, -28, 20, 34, -65, -74, -48, -5, -43, 12, -15, 38, 52; /M: SY='R'; M= -10, -67, 16, 6, -6, -20, -47, -30, -12, -22, -46, 6, -66, -32, 41, 6, -38, -29, -75, -52; /M: SY='E'; M= -24, -80, 32, 61, -83, -27, -47, -10, -9, -68, -56, -38, 27, 18, -44, -14, -43, -49, -94, -78; /M: SY='G'; M= 3, -56, -55, -51, -21, 13, -56, -22, -22, 11, 5, 12, -66, -10, -17, 6, 4, -21, -73, -57; /I: I=-26; MI=0; MD=-65; IM=0; DM=-65; /M: SY='G'; M= -17, -72, -7, -15, -85, 62, -51, -87, -21, -53, -67, 35, -67, -8, -17, 5, -40, -77, -89, -79; /M: SY='L'; M= -48, -51, -93, -78, -36, -90, -82, 36, -78, 42, -5, -82, -81, -68, -77, -10, -40, 28, -77, -58; /M: SY='Y'; M= -23, -63, -6, 23, -35, -74, -44, -6, -7, -1, -32, -50, -68, 12, -16, -39, 14, -5, 20, 32; /M: SY='E'; M= -10, -69, -47, 23, -48, -29, 23, -41, -5, -12, -42, -23, -4, -4, -14, -21, -45, 1, -65, 17; /M: SY='L'; M= -24, 10, -88, -75, 7, -81, -74, -13, -67, 37, -17, -75, -7, -62, -24, -9, -10, -20, -71, -47; /M: SY='S'; M= 8, 6, -44, 3, -82, -54, 3, -80, -2, -81, -65, 7, -3, -4, 5, 34, -7, -64, -87, -68; /M: SY='Q'; M= -23, -73, -22, -9, -72, -69, -47, -49, -4, -17, -2, 12, 15, 27, 25, -20, -45, -15, -82, -74; /M: SY='H'; M= -25, -77, 11, 7, -81, -25, 35, -80, -12, -50, -62, -12, -10, -3, 27, 7, 1, -70, -88, -62; /M: SY='D'; M= -22, -77, 40, 36, -67, -27, 2, -76, -44, -32, -60, -11, -65, 18, -53, 15, -40, -69, -80, -13; /M: SY='W'; M= 29, -58, 14, -52, -27, -2, -78, 7, -69, -20, -42, -61, -69, -61, -75, -39, -47, -7, 31, -57; /M: SY='E'; M= -49, -78, -16, 25, -72, -10, -61, -48, -9, -2, -43, -20, -10, -7, -19, -5, -48, -16, -94, -80; /M: SY='D'; M= -58, -84, 28, 6, -62, -2, -55, -17, -23, -9, -45, -47, -76, 25, -18, -52, -23, -52, -80, -13; /M: SY='I'; M= -3, -62, -90, -79, -53, -83, -82, 26, -70, 20, -23, -37, -84, -69, -22, -28, -52, -10, -90, -70; /M: SY='L'; M= -60, -71, -26, -33, -56, -29, -76, -16, -59, 26, -25, -71, -87, -60, 5, -59, -1, 1, -88, -75; /M: SY='S'; M= -12, -65, -64, -56, -22, -27, -59, -44, -7, -27, -49, 1, -76, -12, -18, 4, -12, 0, -74, -10; /M: SY='R'; M= -38, -81, -19, 5, -67, -79, -60, -54, -18, 12, -39, -20, -79, -40, 35, -23, -21, -57, -92, -78; /M: SY='R'; M= -61, -86, -60, 1, -66, -28, -51, -2, -28, -41, -54, -14, -83, -40, 55, -28, -56, -49, -79, -10; /M: SY='V'; M= -10, -62, -80, -70, -64, -27, -74, -4, -57, -8, 5, -27, -80, -60, 3, -45, 12, 15, -85, -75; /M: SY='E'; M= -63, -82, -1, 3, -28, -86, -66, -28, -57, -44, -58, 0, -87, -7, -15, -28, -21, -6, -94, -71; /M: SY='W'; M= -75, 6, -88, -77, -73, -98, 0, -42, -10, -20, -56, -27, -13, -58, 7, -69, -30, -67, 55, -63; /I: I=-28; MI=0; MD=-71; IM=0; DM=-71; /M: SY='P'; M= -71, -96, -14, -4, -86, -99, -5, -33, -81, -17, -59, -78, 40, -63, -87, -36, -70, -39,-112, -88; /M: SY='N'; M= -43,-105, -90, -89,-106, -32, -12, -80, -36, -52, -82, -11, -19, -77, -29, -78, -83, -37,-123,-100; /M: SY='R'; M= -42, -97,-114, -97, -97,-111,-105, -43, -39, -30, -68,-100,-110, -86, -26, -41, -33, -31,-123,-108; /M: SY='W'; M= -94,-132, -19, -38,-119, -41, -98,-141, -39,-135,-115, -85,-115, -77, -4, -44, -93,-128, 31,-100; /M: SY='S'; M= -80,-113, -90, -28,-125, -25,-101, -59, -40,-114,-103, -88,-111, -78, -26, -18, -39, -95,-137,-122; /I: E1=0; IE=-255; DE=-255;» more |
Numerical results [info]
| Total number of hits | 7 in 7 different sequences |
| Number of true positive hits | 7 in 7 different sequences |
| Number of 'unknown' hits | 0 |
| Number of false positive hits | 0 |
| Number of false negative sequences | 0 |
| Number of 'partial' sequences | 0 |
| Precision (true positives / (true positives + false positives)) | 100.00 % |
| Recall (true positives / (true positives + false negatives)) | 100.00 % |
Comments [info]
| Taxonomic range [info] | Eukaryotes |
| Maximum number of repetitions [info] | 1 |
| Matrix type [info] | protein_domain |
| Scaling database [info] | reversed |
| Author [info] | CJA_Sigrist |
| Feature key [info] | DOMAIN |
| Feature description [info] | RINT1/TIP20 |
| Version [info] | 3 |
Cross-references [info]
| UniProtKB/Swiss-Prot True positive sequences |
7 sequences
MAG2L_ARATH (Q8GXP1), MAG2_ARATH (Q9STU3), RINT1_DROME (Q9VS46), RINT1_HUMAN (Q6NUQ1), RINT1_MOUSE (Q8BZ36), TIP20_SCHPO (Q9C0W8), TIP20_YEAST (P33891)» more
|
| PDB [Detailed view] |
2 PDB
3FHN; 8EKI |