Entry: PS51435

Forthcoming changes to the profile format
General information about the entry

Entry name [info] AP_NUCLEASE_F1_4
Accession [info] PS51435
Entry type [info] MATRIX
Date [info] FEB-2009 (CREATED); OCT-2013 (DATA UPDATE); JUN-2014 (INFO UPDATE).
PROSITE Doc. [info] PDOC00598
Associated ProRule [info] PRU00764

Name and characterization of the entry

Description [info] AP endonucleases family 1 profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=267;
/DISJOINT: DEFINITION=PROTECT; N1=6; N2=262;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=1.3590838; R2=0.0045032; TEXT='NScore';
/NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=205.36457; R2=32.85511; TEXT='HScore';
/CUT_OFF: LEVEL=0; SCORE=3807; N_SCORE=18.5; H_SCORE=117958; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=1142; N_SCORE=6.5; H_SCORE=37726; MODE=1; TEXT='?';
/DEFAULT: M0=-14; D=-100; I=-100; B1=-500; E1=-500; MI=-105; MD=-105; IM=-105; DM=-105;
...
                A    C    D    E    F    G    H    I    K    L    M    N    P    Q    R    S    T    V    W    Y
/I:         B1=0; BI=-105; BD=-105;
/M: SY='M'; M= -26, -32, -45, -38,  15, -43, -26,  23, -34,  36,  84, -36, -38, -28, -33, -32,   1,   7, -34, -12;
/M: SY='K'; M= -23, -41, -21,  -9, -41, -32, -18, -42,  59, -39, -28, -13, -30,  21,  59,  14, -20, -37, -37, -27;
/M: SY='I'; M= -30, -37, -49, -45,  54, -50, -40,  60, -41,  22,  -1, -40, -42, -41, -42, -37, -24,  21, -25,  -5;
/M: SY='V'; M=   8,  28, -41, -36,   9, -39, -37,  27, -34,  11,  35, -33, -37, -34, -36, -23,  18,  41, -40, -20;
/M: SY='T'; M=  -9, -26, -19, -21, -34, -20, -26, -29, -20, -33, -28,  -8, -24, -17, -26,  60,  63, -21, -48, -29;
/M: SY='W'; M= -36, -51, -58, -43,  52, -40, -47, -22, -36, -21, -26, -51, -44, -38, -38, -41, -40,  -9, 143,  29;
/M: SY='N'; M= -51, -60,   4, -39, -80, -26, -11, -78, -21, -93, -66, 201, -72, -25, -39, -14, -19, -83,-118, -70;
/M: SY='V'; M=   0, -30, -43, -39, -18, -44, -46,  40, -36,  -3,  -6, -37, -38, -38, -39, -26,   6,  66, -47, -24;
/M: SY='N'; M= -10,  22,  29, -17, -41, -15,  -9, -40, -13, -45, -34,  91, -36, -15, -21,  -9, -11, -40, -59, -35;
/M: SY='G'; M= -10, -36, -25, -34, -44,  78, -31, -49, -29, -47, -37, -12, -30, -25, -36,  32, -21, -42, -38, -38;
/M: SY='I'; M= -29, -36, -48, -43,  27, -51, -39,  55, -41,  45,   3, -42, -42, -38, -41, -38, -24,  16, -31, -12;
/M: SY='R'; M=   6, -38, -22, -16, -33, -31, -17, -32,  21,   1, -21,  31, -36,  10,  65, -19, -22, -29, -40, -27;
/M: SY='A'; M=  42, -29, -22, -22, -35,  -4, -25, -24, -22, -12, -22,  32,  10,   9, -27,  13,  16,  -5, -43, -32;
/I:         I=-28; MD=-29;
/M: SY='W'; M=  13, -42, -42, -32,  19, -39, -36,  -3, -20, -13, -22, -36,  18, -28,  39, -29, -28,  11,  47, -21; D=-28;
/I:         I=-28; MI=-29; MD=-29; IM=-29; DM=-29;
/M: SY='L'; M= -32, -39, -51, -43,  33, -52, -39,  31, -42,  37,  16, -45, -48,  -5, -41, -40, -28,  19, -34, -15; D=-28;
/I:         I=-28; DM=-29;
/M: SY='R'; M= -22, -38, -18, -11, -40, -28,  19, -41,  38, -38, -27,  22, -31,  29,  54,  20,   1, -36, -42, -26;
/M: SY='Y'; M= -25, -40,  23,   8,   1, -11, -16, -31,  30, -14, -23, -17,   6,  12,   5,  -3,   2, -31, -24,  47;
/I:         I=-11; MD=-11;
/M: SY='H'; M= -32, -45,   0,  -7,  15, -37,  52, -38,   0, -19,   2,   7,   2,   5,   5,   9, -27, -39, -46, -21; D=-11;
/I:         I=-11; MD=-11;
/M: SY='P'; M= -19, -57,  -5, -35, -56, -44, -43, -18, -32, -52, -46, -37,  45, -35,  12,  18, -32, -44, -61, -50; D=-11;
/I:         I=-11; MD=-11;
/M: SY='W'; M= -26,  10,  -6,  -8, -11, -59, -57, -63, -14, -58, -57, -51, -60,  -2, -46, -50, -55, -63,  82, -37; D=-11;
/I:         I=-11; MI=0; MD=-11; IM=0; DM=-11;
/M: SY='W'; M= -51, -66, -47, -44, -57, -53, -48, -57,   0, -28, -50,  15,  20,  -6, -42, -18, -45, -60,  44, -50; D=-11;
/I:         I=-11; DM=-11;
/M: SY='Q'; M= -48, -61, -43,  -7,  -6, -57, -42, -44, -36,  -4, -37, -11,   1,  31, -11, -42, -17, -46, -56, -41; D=-11;
/I:         I=-11; DM=-11;
/M: SY='S'; M=  11,  24,   0,  16, -35,  23, -21, -39,   2, -37, -30, -14, -29,  26, -20,  40, -14, -33, -37,   7;
/M: SY='F'; M= -29, -33, -46, -42,  67, -12, -31,  -1, -40,  36,  -4, -40, -46, -41, -38, -34, -26,  22, -18,  18;
/I:         I=-28; MI=0; MD=-29; IM=0; DM=-29;
/M: SY='L'; M= -23, -37,   3,  23, -24, -36, -23,   3,   0,  29, -12, -22, -33,  10,  27,  12,  -2, -17, -40, -24;
/M: SY='E'; M=  -4, -38,  23,  27, -42,  -2,  18, -41,   6, -39, -31,   9,  14,  24,  18,  21,   2, -36, -45, -30;
/M: SY='W'; M= -27, -37, -40, -37,  14, -39, -31,  25, -33,  23,  17,   2, -40, -31, -35,  -8,  -2,  11,  90,  25;
/M: SY='L'; M= -13, -31, -47, -40,  34, -46, -35,   6, -40,  54,   2, -43, -45, -37, -38, -35, -23,  32, -31, -11;
/M: SY='Q'; M=   5, -40,  31,  30, -42,  -8, -18, -32,  15, -31,  16, -15, -28,  54,  10, -16, -22, -12, -42, -28;
/M: SY='R'; M=  -8, -40,  21,  40,  -2, -34, -18, -34,  27, -33, -28, -17, -29,  -7,  41,  -1, -21, -14, -35,   8;
/M: SY='H'; M= -26, -37, -18,  35,  21, -37,  42,  -1,   3,  24, -13,   3, -33, -15,   0,  -2, -22, -20, -36, -15;
/M: SY='D'; M=  -6, -40,  48,  -8, -45,  13, -18, -43,  26, -43, -33,  32,   6,  25,  22, -15, -21, -40, -46, -32;
/I:         I=-30; MI=0; MD=-32; IM=0; DM=-32;
/M: SY='P'; M=  42, -38, -30, -21, -11, -22, -32, -32, -26, -37, -29, -29,  83, -26, -34,   4, -17, -28, -39, -35;
/M: SY='D'; M= -29, -43,  96,   5, -50, -26, -16, -48, -18, -47, -46,   2, -30, -17, -26,   1, -19, -45, -65, -33;
/M: SY='I'; M= -22, -35, -48, -44, -14, -51, -49,  66, -40,   2,  -1, -40, -39, -39, -43, -33, -18,  55, -42, -22;
/M: SY='I'; M= -25, -35, -48, -43, -10, -51, -43,  60, -41,  38,   3, -42, -41, -37, -42, -36, -21,  37, -38, -19;
/M: SY='C'; M=  25, 104, -37, -35,   3,  -6, -37, -25, -34,  -7, -23, -27, -41, -35, -38,  -1,  -1,  -5, -45, -30;
/M: SY='L'; M= -30, -33, -48, -41,  28, -49, -34,  25, -41,  61,   6, -45, -46, -36, -39, -39, -25,   9, -30, -11;
/M: SY='Q'; M= -22, -48, -17,   3, -53, -30, -10, -38,  -2, -34, -20, -13, -29, 105,  -3, -11, -25, -40, -35, -24;
/M: SY='E'; M= -46, -88,  12, 178, -93, -78, -33, -95,  -8, -79, -72, -39, -36,   7, -28, -39, -47, -79, -86, -73;
/M: SY='T'; M= -18, -27, -33, -32, -19, -40, -36,   2, -30,  21,  -8, -25, -33, -32, -34, -14,  58,  44, -47, -24;
/M: SY='K'; M= -27, -42, -21,  -8, -37, -34, -22, -42,  76, -40, -29, -14, -29,  -4,  42, -22, -23, -39,  51, -24;
/M: SY='L'; M=   6,  28, -43, -38, -12, -41, -36,  35, -37,  44,  20, -37, -40, -33, -38, -29,  -2,  18, -39, -21;
/M: SY='Q'; M=  10, -36,   5,   5, -41, -25,  20, -37,   8, -36, -27,   6,  11,  41,  20,  26,  14, -32, -43, -28;
/I:         I=-11; MD=-12;
/M: SY='C'; M=   7,  25, -53, -12, -66, -54, -60, -56, -53, -60, -56, -52,  -9, -50, -59, -13, -11, -28, -75, -64; D=-11;
/I:         I=-11; MI=0; MD=-12; IM=0; DM=-12;
/M: SY='K'; M= -10, -41,  42,  12, -44, -30, -18, -43,  54, -41, -32,  11,   5,  14,  25, -18, -21, -39, -43, -31;
/M: SY='D'; M= -25, -41,  63,   7, -40,  29,  17, -38,   2,  -7, -30,  14, -31,  11, -22, -18, -23, -38, -49, -30;
/M: SY='M'; M=  -5, -34, -21,  18, -32, -30, -23, -20,  25, -10,  33, -18,   7,  20, -14,  20,  20,   2, -41, -27;
/M: SY='F'; M= -26, -36, -31,  10,  32, -40, -29,  14,  -4,  29,  15, -31,  29, -25, -29,  -7,  -1,  -1, -31, -15;
/M: SY='P'; M= -24, -40,  -2,   0, -41, -32, -25, -36,  27, -39, -29, -18,  64, -15,  34,  -1,  34, -32, -43, -33;
/M: SY='K'; M=  21, -37,  24,   3, -35, -28, -22, -11,  30,  -4, -21,   9,   4,  26,   5, -17, -20, -12, -41, -29;
/I:         I=-9; MD=-9;
/M: SY='H'; M= -12, -47,  23,  36, -37, -38,  56, -13,  -6, -13, -27, -21,   1,  20, -23, -26, -29, -34,  39, -24; D=-9;
/I:         I=-9; MD=-9;
/M: SY='G'; M=   5, -41, -30,  -4, -31,  30,  13, -27,   8,   8, -22, -26,  -4,  10, -26, -23, -28, -11, -39,   1; D=-9;
/I:         I=-9; MD=-9;
/M: SY='A'; M=  27, -40, -28,  13, -40, -33, -31, -26, -20, -16, -27,   0,  10,   8,  14, -21,  -7,   5, -48, -37; D=-9;
/I:         I=-9; MD=-9;
/M: SY='I'; M=   5, -40, -39,  -6,   7, -44, -39,  30,  -8,  13, -14, -36, -41,   1, -33, -29,  -4,  11, -41, -25; D=-9;
/I:         I=-9; MD=-9;
/M: SY='K'; M=   3, -44, -48, -38, -31, -48, -44,  12,  18,  14,  14, -42, -47, -35, -31, -37, -31,  14, -50, -35; D=-9;
/I:         I=-9; MI=0; MD=-9; IM=0; DM=-9;
/M: SY='P'; M= -28, -46,  30,  40, -44, -35, -25, -38,   2, -19,   7, -21,  45,  10, -23,   5, -23, -38, -48, -36; D=-9;
/I:         I=-9; DM=-9;
/M: SY='G'; M=  13, -36,  17, -25, -44,  67, -28, -45,  -5, -44, -35,  13, -30, -24, -30, -11,   0, -38, -41, -37;
/M: SY='Y'; M= -31, -42, -38, -38,  33,  -7, -10, -14, -32,   9, -11, -36, -45, -29, -30, -30, -29,  -6,  51,  91;
/I:         I=-22; MI=0; MD=-23; IM=0; DM=-23;
/M: SY='H'; M= -28, -42,  34,  35, -31,  -3,  69, -44, -14, -38, -30,  35, -30, -11,   3, -19, -24, -43,  51,  10;
/M: SY='H'; M=  13,  24, -24, -23, -25, -23,  45, -21, -23, -27, -22,   7, -33,  11, -25,  44, -11,  14, -38,  23;
/M: SY='Y'; M= -30, -39, -34, -33,  54, -38,  53, -19, -30, -16, -16, -28, -41, -27, -28,  -5,  -4,  -7,  54,  73;
/M: SY='W'; M= -33, -43, -52, -42,  52, -43, -37,   3, -37,   8, -15, -46, -45, -38, -37, -38, -32,  11, 120,  40;
/I:         I=-18; MD=-18;
/M: SY='S'; M= -14,  31, -25, -27, -34,   2, -28, -12, -23, -15, -28,   3, -32, -20,  -3,  54,  27, -25, -48, -32; D=-18;
/I:         I=-18; MD=-18;
/M: SY='C'; M=   6,  44, -42, -15,  30, -41, -34,  13, -38,  17, -14, -38, -45, -36, -40, -10, -26,   0, -30,  23; D=-18;
/I:         I=-18; MD=-18;
/M: SY='P'; M=  14, -40,  -2, -23, -46, -25, -32, -39, -28, -45, -36, -23,  67, -25, -35,  39,   5, -35, -49, -41; D=-18;
/I:         I=-18; MI=0; MD=-18; IM=0; DM=-18;
/M: SY='H'; M= -10, -50, -35, -29, -47, -14,  39, -42,  18, -22, -34,  -2,   1,   2,  -4,  -7, -33, -24, -56, -36; D=-18;
/I:         I=-18; DM=-18;
/M: SY='D'; M=  18, -37,  28, -25, -43,  22, -33, -15, -30, -38, -34,   8, -35, -28, -36,   8,  23, -14, -52, -38; D=-18;
/I:         I=-18; DM=-18;
/M: SY='R'; M=   9, -39,  23,  -8, -41, -29, -18, -35,  39, -36, -27,  12, -32,  38,  46, -16, -21, -14, -41, -28;
/M: SY='K'; M=   7, -36, -20,   7, -35, -29, -24, -35,  60, -21, -27, -16, -28,  -8,  16,  12,   3, -31,  47, -25;
/M: SY='G'; M= -15, -39, -26, -31, -44,  76, -30, -50,   0, -46, -35, -13, -31, -23,  18, -13,  -5, -43, -37, -37;
/M: SY='Y'; M= -33, -44, -31, -29,   8, -40,  42, -23, -17,  -5, -13, -29, -43, -18,  32, -28, -29, -27,  -2,  93;
/M: SY='S'; M=  23, -30, -19, -21, -32,   5,  15, -36, -18, -37, -29,  23, -30, -14,   3,  57,  -8, -29, -39,   7;
/M: SY='G'; M= -12, -40, -27, -39, -46,  87, -34, -54, -33, -49, -38, -13, -31, -30, -40, -12, -31, -47, -37, -41;
/M: SY='V'; M= -15, -28, -35, -30, -22, -39, -39,   7, -29, -10, -11, -27, -35,   4, -32,   1,  38,  63, -50, -26;
/M: SY='G'; M=  47, -31, -32, -31, -35,  51, -32,  -4, -29, -26,  32, -22, -31, -26, -34, -11, -22, -19, -37, -32;
/M: SY='I'; M= -24,  22, -39, -35,  21, -43, -35,  28,  -7,  26,  23, -31, -38, -32, -32, -25,  26,  27, -36, -16;
/M: SY='F'; M= -31, -35, -47, -41,  53, -46, -28,   8, -39,  45,  27, -43, -46, -36, -36, -37, -27,   4,  44,  31;
/M: SY='C'; M= -15,  47, -32, -32, -18, -32, -30,  17, -29, -16, -16, -23, -35, -27, -33,  34,  25,  35, -37,  28;
/M: SY='R'; M= -27, -43, -22, -10, -41,  -7, -19, -44,  60, -40, -28, -15, -32,  -4,  70, -21, -25, -39, -37, -27;
/M: SY='H'; M= -23, -40,   0,   4, -32, -11,  57,  16,  37, -24, -18, -15, -31,  24, -10,  -3, -21,  10, -43, -21;
/M: SY='C'; M=   9,  68,  18,  11, -39,  -7, -28, -33,  18, -35, -30, -17,  25, -19, -21,  12,   2, -11, -47, -35;
/I:         I=-14; MD=-15;
/M: SY='C'; M= -21,  24, -49, -19, -45, -53, -52, -12, -50,  -4, -35,  -8, -58, -46, -54,   3, -36,   0, -67, -50; D=-14;
/I:         I=-14; MI=0; MD=-15; IM=0; DM=-15;
/M: SY='Q'; M= -44, -60, -49, -41, -58, -56, -49, -24,   4, -26, -44, -41, -55,  18, -38,   3,   5, -46, -66, -52; D=-14;
/I:         I=-14; DM=-15;
/M: SY='P'; M= -25, -44,   1, -21, -35, -35, -34, -15, -28,  -9, -22, -32,  91, -31, -37, -25,   0,  22, -45, -37;
/M: SY='V'; M=  -5,  27, -37, -33, -18, -38, -35,  31, -32,  27,  -6,  -6,   3,   1, -35,  -3, -18,  34, -42, -24;
/M: SY='K'; M=  21, -34,  23, -10, -41, -24, -22, -36,  38, -36, -28, -11, -28,  25,  12,  24,  17, -29, -42, -29;
/M: SY='V'; M=  34, -29, -37, -34, -22, -32, -38,  30, -32,   2,  -9,   1, -37, -31, -36, -20, -15,  50, -44, -26;
/M: SY='E'; M=  -2, -38, -14,  44, -36, -31,  19, -16,  -8, -13, -25, -19,  11,  -8,  35,  24,  -1, -28, -43, -28;
/M: SY='Y'; M= -29, -42, -18,  42,  35, -41, -14,  -2, -15, -20, -19, -27, -34, -14,  19, -25,  -5, -23, -13,  65;
/M: SY='G'; M= -15, -39, -24, -30, -41,  71, -30, -46, -27, -45, -35,  10,   6,   7, -33,   5,   1, -42,  39, -34;
/I:         I=-30; MI=0; MD=-32; IM=0; DM=-32;
/M: SY='I'; M= -28, -35, -45, -41,  29, -47, -37,  53, -39,  42,   1, -38, -41, -36, -40, -13,  -5,   5, -31, -12;
/M: SY='G'; M=   2, -34,   6, -24, -40,  48, -28, -37, -24, -40, -32,  11,  27, -24, -32,  16,  39, -31, -44, -35;
/M: SY='G'; M=   8, -35,  11, -12, -29,  47, -31,   9, -30,  10, -18, -19, -33, -26, -35,   3,  -2,  -6, -40, -30;
/I:         I=-20; MI=0; MD=-21; IM=0; DM=-21;
/M: SY='P'; M=  -9, -40,  51,  17, -41, -28, -24, -35,   1, -20, -31, -13,  56, -17, -24,  10,  16, -33, -48, -34;
/I:         I=-7; MD=-7;
/M: SY='G'; M= -32, -50,  12, -40, -44,  19, -43,   2, -43, -17, -34,   1, -49, -40, -48,   7, -31,   1, -60, -44; D=-7;
/I:         I=-7; MI=0; MD=-7; IM=0; DM=-7;
/M: SY='E'; M= -23, -41,  23,  40, -35,   8, -24,  -5,  23, -29,  13, -17,   8,  10, -16, -20,  -2, -12,  36, -28;
/M: SY='H'; M= -30, -41,  20,  -1,   3, -39,  77,  10, -23,  12,  16, -20, -36, -19,   4, -28, -27,  -5,  47,  -9;
/M: SY='D'; M= -11, -41,  85,  26, -38, -29, -16, -43, -17, -41, -39,  -4, -29, -15, -25, -17,   4, -39, -49,  11;
/M: SY='Q'; M=  10, -33, -20, -18,   1, -23, -21,  -3,   2, -13, -22,  33,   6,  36, -20,  34,   1, -23, -39, -24;
/M: SY='E'; M= -23, -45,  20,  77, -48, -36, -15, -45,  -4, -39, -32, -16, -21,  52, -12, -18, -24, -40, -42, -33;
/M: SY='G'; M=   3, -39, -27, -34, -45,  80, -31, -51, -24, -46, -36, -14, -32, -26,  12, -13, -30, -43, -37, -38;
/M: SY='R'; M= -28, -45, -26, -15, -39, -38, -15, -45,  12, -38, -27, -18, -38,  -3,  92,   0, -26, -38, -39, -26;
/M: SY='C'; M=  -7,  73, -43, -40, -17, -42, -41,  42, -37,  -8, -10, -35, -41, -37, -40,  -9, -17,  47, -42,   5;
/M: SY='I'; M=  -3, -35, -44, -40, -14, -44, -42,  62, -38,  22,  -1, -37, -38, -35, -40,  -7, -18,  35, -39, -21;
/M: SY='M'; M=  -6, -32,   3,  -7, -19, -37, -29,  20, -28,  24,  50, -25, -33, -25, -32,  -3,  28,  16, -42, -22;
/M: SY='A'; M=  36, -27, -36, -31, -20, -30, -35,  -3, -31,  30,  -8, -30, -35, -29, -34, -16,  27,  29, -41, -25;
/M: SY='E'; M= -23, -42,  43,  66, -46, -34, -17, -42,  -8, -38, -33, -12, -22,  41, -16, -15,  16, -37, -46, -33;
/M: SY='F'; M= -32, -36, -42, -38,  60, -45,  38,   8, -37,  35,  -4, -36, -45, -34, -34, -35, -27,   2, -16,  43;
/M: SY='D'; M=  15, -38,  39,  27, -43,  25,  22, -42,  -2, -40, -32, -12,   8,   7, -22,   2,   2, -35, -46, -31;
/I:         I=-22; MI=0; MD=-23; IM=0; DM=-23;
/M: SY='S'; M=  23, -32, -25, -23,  -4,  31,  20, -28,   0, -30,   7,   2, -31,   4, -24,  33, -15,  -5, -39, -24;
/I:         I=-24; MI=0; MD=-25; IM=0; DM=-25;
/M: SY='F'; M= -29,  21, -48, -43,  68, -46, -35,  20, -40,  21,  25, -40, -45, -42, -39, -35, -24,  30, -22,   0;
/M: SY='T'; M=  -4,  27, -35, -33,  19, -39, -31,  26, -24, -12, -13, -28, -36, -29,  15, -20,  33,  30, -32,  22;
/M: SY='V'; M= -21, -32, -47, -41, -12, -49, -44,  41, -39,  31,   0, -42, -42, -38, -40, -33, -18,  59, -43, -21;
/M: SY='F'; M=   6, -33, -44, -40,  46, -42, -37,  42, -37,  24,  16, -36, -39, -36, -38, -28,  -1,  19, -28,  -9;
/M: SY='N'; M= -17, -30,  -8, -20, -39,  12, -15, -36, -15, -41, -31,  72, -31,  10, -22,  33,  28, -33, -51, -32;
/M: SY='V'; M=  -2, -29, -36, -34, -19, -10, -37,  14, -31,  18,  17, -28, -34, -32, -35, -18,  41,  43, -44, -24;
/M: SY='Y'; M= -34, -45, -33, -36,  18, -41,   0, -19, -28, -16, -13, -35, -46, -24, -25, -29, -28, -25,  10, 110;
/M: SY='C'; M=  -3,  87, -39, -37,   4,  -8, -38,   3, -35,   7, -15, -29, -41, -36, -39,  -2,  11,  28, -45, -26;
/M: SY='P'; M= -27, -51, -31, -20, -44, -33, -34, -26, -27, -39, -29, -37, 106, -31, -38, -27, -21,   1, -43, -43;
/I:         I=-30; MD=-32;
/M: SY='N'; M=   5, -35, -10, -19, -41, -20,  43, -41,   2, -42, -30,  70, -35,  11,   6,  16, -15, -38, -53, -29; D=-30;
/I:         I=-30; MI=-32; IM=-32; DM=-32;
/M: SY='N'; M=  31, -30, -17, -26, -39,  42, -23, -33, -22, -38, -30,  53, -32, -21, -29,  11,   2, -13, -45, -35;
/M: SY='G'; M=  -1, -34,   2,  12, -40,  49, -26, -36, -21, -39, -32,   6, -29, -18,  -8,  33,   5, -11, -43, -34;
/M: SY='W'; M=  28, -32,  15, -19, -33, -21, -25, -32, -17, -18, -27,   6,   3, -17,  13,  38,  15, -26,  48, -27;
/I:         I=-19; MI=0; MD=-19; IM=0; DM=-19;
/M: SY='G'; M= -16, -38,  42, -21, -45,  68, -26, -48, -26, -46, -38,  15, -30, -24, -34,   2,   0, -43, -44, -37;
/M: SY='D'; M=  -4, -35,  23,  22, -27, -34,  18, -19,  -3,  20, -16, -20,   9, -17,  -1,  -2,  17,  -3, -44, -25;
/I:         I=-19; MI=0; MD=-19; IM=0; DM=-19;
/M: SY='E'; M=  -8, -39,  29,  46, -40, -31, -20,  -9,  23, -33, -28,  23,   8,  10, -14, -17,   3,  -8, -45, -32;
/M: SY='R'; M= -24, -43, -24, -16, -40,  20, -19, -46,  34, -40, -29, -16, -34,  -7,  76,  -1, -25, -39, -38, -28;
/M: SY='F'; M= -31, -38,  -3,  10,  47, -43,  22,  13, -28,  30,  -7, -30, -39,  10, -29, -31, -26, -13, -21,  34;
/M: SY='E'; M=   6, -39,  49,  50, -40, -30, -21, -11,   2, -32,   7, -14,   9, -10, -20,  -4,  -2, -28, -47, -32;
/M: SY='Y'; M= -11, -42, -25,  16,  36, -38, -12, -28,   8, -23, -20, -26, -37,  11,  40, -24, -27, -29, -11,  67;
/M: SY='R'; M= -28, -44, -23, -10, -40, -37, -17, -44,  56, -39, -28, -16, -33,  -3,  78, -22, -25, -39, -37, -26;
/I:         I=-30; MI=0; MD=-32; IM=0; DM=-32;
/M: SY='M'; M=   6, -38,   0,  12, -23, -34,  23, -21,   2,  13,  40, -22, -34,  28,  30, -22, -24, -22, -34,  15;
/M: SY='Q'; M=   4, -39,   1,  12, -31, -34,  26, -24,  -7,  12, -16, -21, -34,  46,  45, -20, -24,  -8, -40, -23;
/M: SY='W'; M= -38, -46, -56, -44,  74, -41, -41, -22, -38, -16, -23, -48, -46, -42, -38, -40, -39, -30, 132,  29;
/M: SY='D'; M= -32, -40,  60,   0,  23, -37,  24, -22, -26,  19, -17, -17, -38, -23, -28, -27, -25, -25, -25,  49;
/M: SY='R'; M=  16, -38,  10,  25,   2,  10, -22, -34,  15, -33, -28, -18, -30,  12,  36,  -1, -21, -14, -37, -25;
/M: SY='R'; M=  27, -33,  -2,   3, -28, -30, -26, -15,   2,  10, -16,   3, -34, -17,  32, -18,  -3,  18, -42, -27;
/M: SY='L'; M= -30, -33, -47, -40,  48, -46, -28,   2, -39,  52,  43, -42, -45, -35, -36, -37, -26,   8, -23,  18;
/M: SY='Q'; M=   5, -36, -24,  15, -28, -32, -22,   0, -14,  17,  19, -22, -32,  46,  17,  11,   0, -18, -38, -24;
/M: SY='E'; M=  -9, -41,  -8,  53, -42, -32, -15, -40,  12, -35,   5,  19, -27,  33,  41,  -4, -21, -36, -41, -30;
/M: SY='F'; M= -31, -41, -31,  -1,  55, -41,  14, -22, -11, -18, -18, -28, -41,   6,  48, -28, -27,  -4, -15,  50;
/M: SY='C'; M= -10,  50, -47, -40, -11, -45, -39,  25, -39,  45,  -1, -42, -44, -36, -40, -34, -23,  30,  47, -19;
/M: SY='E'; M=   8, -36, -12,  46, -35, -32, -21, -32,  34,  -4, -24,   4, -26,  -7,  21, -16,  14, -27, -41, -30;
/I:         I=-17; MD=-18;
/M: SY='C'; M= -18,  24,  17, -27, -51, -10, -32, -49,  -6, -27, -40,  21, -47,   5,  22, -28,  -8, -45, -59, -43; D=-17;
/I:         I=-17; MI=0; MD=-18; IM=0; DM=-18;
/M: SY='L'; M= -11, -36, -21,  43, -14, -42, -23, -11, -21,  47,  -5, -33, -35, -16,   2, -29, -25, -15, -32,  14;
/I:         I=-30; MD=-32;
/M: SY='L'; M= -39, -49,  -7,   9, -31, -54, -37,  -5, -30,  25,  13, -42,   3, -30,  13, -41, -35,  -9, -51, -35; D=-30;
/I:         I=-30; MI=-32; IM=-32; DM=-32;
/M: SY='A'; M=  31, -35,  17,  24, -40, -26, -23, -31,  23, -34, -28,   3,  11, -12,  23, -14,   1,  -8, -43, -32;
/M: SY='Q'; M=  30, -37, -22,   2, -39,   0,  23, -13,  24, -32, -24, -17, -30,  38,  30,   3, -20, -27, -39, -27;
/M: SY='G'; M= -18, -38,   4,  -1, -38,  52,  17, -39,  23, -18, -28, -13, -29, -17,   5,  -2,  14, -35, -41, -30;
/I:         I=-28; MI=0; MD=-29; IM=0; DM=-29;
/M: SY='K'; M= -25, -41, -20, -12, -38,  -6, -21, -42,  58, -41, -30,  23,  13,  -8,  41,  -4, -21, -39,  48, -26;
/M: SY='P'; M= -28, -48,  10,  26, -44, -33,  41, -42,  23, -42, -31, -20,  75, -12,  22, -23, -23, -42, -44, -31;
/M: SY='V'; M= -21, -31, -47, -40, -12, -48, -40,  33, -38,  34,  28, -42, -42, -37, -39, -33, -18,  57, -43, -21;
/M: SY='V'; M= -23, -33, -47, -42,  12, -49, -43,  47, -40,  28,   0, -42, -42, -39, -41, -34, -19,  53, -39, -17;
/M: SY='W'; M= -10, -39, -50, -41,  -8, -44, -43,  35, -39,  40,  -3, -45, -42, -35, -39, -36, -27,  17, 101, -11;
/M: SY='C'; M=  -3,  73, -40, -36, -21,  -5, -30,  -6, -32,  10,  71, -30, -38, -30, -34, -24,  11,  21, -45, -24;
/M: SY='G'; M= -12, -40, -27, -39, -46,  87, -34, -54, -33, -49, -38, -13, -31, -30, -40, -12, -31, -47, -37, -41;
/M: SY='D'; M= -61, -88, 197,  12,-102, -55, -32, -98, -36, -95, -93,   4, -60, -34, -53, -37, -40, -92,-133, -67;
/M: SY='W'; M= -29, -34, -48, -40,  15, -46, -31,  14, -38,  53,  41, -44, -44, -33, -36, -38, -26,  14,  53,  14;
/M: SY='N'; M= -51, -60,   4, -39, -80, -26, -11, -78, -21, -93, -66, 201, -72, -25, -39, -14, -19, -83,-118, -70;
/M: SY='V'; M= -20,  45, -45, -42, -17, -47, -47,  50, -38,  -3,  -5, -37, -40, -40, -41, -29,   0,  59, -47, -25;
/M: SY='A'; M=  64,  52, -31, -25, -36, -16, -32, -28, -27, -16, -24, -24, -32, -23, -31,  18, -14, -17, -41, -34;
/M: SY='H'; M= -30,  15, -21, -19, -34, -33,  94, -39, -18, -17, -21,  10,  60, -16,  14, -23, -26, -40, -53, -16;
/M: SY='E'; M=  -7, -38,  35,  42,  -2, -31, -17, -37,  -9, -35, -30,  21, -27,  27,  19, -14,  22, -33, -43, -26;
/M: SY='D'; M=   7, -39,  44,  38, -34, -33, -23, -25, -14,   6, -23, -19,  21, -14,  18, -21, -22,  -6, -45, -30;
/M: SY='I'; M=  -9, -39, -35,  -3, -15, -42,  21,  61, -28,   5,  23, -30, -35, -25,  -2, -10, -21,   4, -35,   9;
/M: SY='D'; M= -31, -44,  98,   6, -51, -27, -16, -49, -18, -47, -47,   2, -30, -17, -26, -19, -20, -46, -66, -33;
/M: SY='H'; M= -22,  23, -36, -33, -18,  -8,  35,  16, -29,  33,  -6, -28, -39, -27,  -2,   5,  -2,  23, -43, -20;
/M: SY='C'; M=  28,  47, -27, -22,  -6,  14,  21, -36,  21, -33, -27, -18, -33, -17,  18,  15, -19, -29, -35,   7;
/M: SY='N'; M= -28, -40,  55,  19, -42, -24,  25, -14, -16, -40, -33,  61,  31, -15, -24, -16, -17, -36, -55, -32;
/M: SY='P'; M=   5, -44, -30, -22, -31,   9, -30, -36,  -2, -39, -30, -27,  75,   2, -28,   1,  -2, -36,  73,   7;
/M: SY='K'; M=   2, -38,  23,  17, -33,  -5, -22, -28,  36,   0,  30, -17,  12, -13,   6,  -5, -21, -27, -40, -28;
/I:         I=-13; MD=-13;
/M: SY='R'; M= -51, -69, -47, -12,  -9, -60, -44, -63,  -7, -59, -52, -45,   0,  19,  27, -21, -49, -61, -59, -46; D=-13;
/I:         I=-13; MI=0; MD=-13; IM=0; DM=-13;
/M: SY='W'; M=  -7,  18,  31,   0, -34,  36, -28, -35, -22, -14, -29, -13, -30, -21,  -5,  15,  27, -31,  41, -29;
/M: SY='N'; M= -26, -33,   7, -24,  43,  -3,  21, -11, -20, -28, -25,  71, -37, -22, -26,   0,   3, -28, -37, -13;
/M: SY='E'; M=  -6, -40, -16,  35, -35, -34, -22,   5,  31, -13, -22,   3,  10,  18,  29, -19,  -2, -23, -40, -29;
/M: SY='K'; M= -24, -41, -16,  16, -43,  12, -20, -44,  65, -41, -30,   4, -28,  14,  34, -18, -22, -39, -37, -30;
/I:         I=-14; MI=0; MD=-15; IM=0; DM=-15;
/M: SY='H'; M=  -5, -36,   6,  25, -39, -26,  42, -34,  28, -35, -27,  22, -28,  31, -10,  26, -15,  -9, -45, -25;
/M: SY='C'; M=  39,  48,   4,  -3, -41,  15, -30, -37, -25, -38, -31, -20,  39, -22, -32,  24, -16, -28, -44, -37;
/M: SY='G'; M=   1, -37, -28, -31, -38,  69, -30, -38, -26,  -6, -27, -16, -32,   4,  -6,  13, -24, -35, -37, -34;
/I:         I=-10; MD=-11;
/M: SY='F'; M= -38,  25,  -9, -43,  83, -46, -33,  -5, -42, -13, -21, -37, -50, -48, -42, -13, -31, -22, -15,  23; D=-10;
/I:         I=-10; MD=-11;
/M: SY='T'; M= -26, -37, -36, -35, -31, -13, -39, -19, -31,  10, -21, -28,  -1, -34,  -9,  -6,  51,   6, -52, -34; D=-10;
/I:         I=-10; MI=0; MD=-11; IM=0; DM=-11;
/M: SY='P'; M= -37, -51,  24, -28, -39, -46, -39,   0, -13,   1,   6, -32,  51, -35, -40, -33,   9, -28, -54, -40; D=-10;
/I:         I=-10; DM=-11;
/M: SY='E'; M= -12, -54,   8,  41, -55, -10, -33, -45, -24, -48, -41, -31,  41,  21, -32, -29, -33, -22, -53, -46; D=-10;
/I:         I=-10; DM=-11;
/M: SY='E'; M=  -8, -45,  -4,  71, -49, -12,  17, -50, -13, -44, -38,   6, -26,  -6, -22,  -6, -26, -43, -49, -38; D=-10;
/I:         I=-10; DM=-11;
/M: SY='R'; M= -29, -45, -26, -15, -38, -39, -16, -44,  12, -37, -27, -19, -37,  -4,  92, -22,  -2, -37, -39, -25;
/M: SY='Q'; M=  19,  26, -18,  25, -42, -29, -19, -38,   7, -35, -26, -17, -30,  54,  40,   2,  -3, -32, -40, -29;
/M: SY='W'; M= -12, -45,  -2, -29, -19,   9, -37,  -9, -19, -13, -26, -29, -37, -23,  30,   1, -29, -13, 121, -10;
/M: SY='F'; M= -32, -34, -47, -42,  86, -42, -28,   4, -38,   7,  48, -36, -44, -40, -36, -10, -26, -12, -12,  10;
/I:         I=-19; MI=0; MD=-19; IM=0; DM=-19;
/M: SY='D'; M=   6, -36,  54,  21, -42,  -2,  17, -39, -15, -38, -32,  -8, -27,  10,   3,  14,  25, -33, -50, -30;
/M: SY='N'; M=  -2, -34,  12,  18, -38,  -4, -17, -38,  -9, -22, -30,  40, -31, -10,  35,  37, -13, -33, -46, -31;
/M: SY='L'; M= -27,  28, -45, -40,  34, -45, -34,  30, -39,  45,  24, -39, -43, -35, -38, -10, -22,  12, -31, -12;
/M: SY='L'; M= -28, -32, -46, -40,  18, -12, -31,   3, -40,  63,  27, -42, -45, -34, -37, -37, -26,   6, -32, -14;
/M: SY='P'; M=  20, -36,  18,  33, -42,   2, -24, -33, -18, -37, -30, -17,  37,  13, -25,  29, -15, -11, -44, -34;
/I:         I=-8; MI=0; MD=-8; IM=0; DM=-8;
/M: SY='W'; M= -12, -38,  20,   4, -27, -36, -26,  -5,  30,   9, -18, -19, -32, -15,  30, -21,  16,  -3,  43, -23;
/M: SY='G'; M= -17, -41,   6, -24, -43,  67, -29, -42, -26, -23, -31, -15,  32,  24, -32, -14,  -6, -40, -39, -36;
/I:         I=-30; MI=0; MD=-32; IM=0; DM=-32;
/M: SY='F'; M= -31, -35, -47, -41,  56, -11, -30,  -5, -39,  46,  26, -41, -45, -36, -37, -36, -29, -11,  55,  17;
/M: SY='V'; M= -11, -30, -35, -33,  11, -40, -35,  15, -30,  10,  16,   2, -37,  -1, -33, -22,  22,  52, -42, -19;
/I:         I=-30; MI=0; MD=-32; IM=0; DM=-32;
/M: SY='D'; M= -30, -43,  94,   3, -41, -28, -16, -45, -18, -44, -42,   0, -30, -18, -26, -18,  -1, -42, -55,   7;
/M: SY='T'; M=   3, -27, -25, -26, -30,  -2, -31,  -1, -24, -23, -21, -15, -28, -23, -30,  40,  54,  22, -47, -28;
/M: SY='F'; M=  -6,  20, -38, -36,  57, -13, -23, -17, -29,  -4, -17, -31, -41, -31,  -5,  -4,  -2,  -6,  52,  54;
/M: SY='R'; M= -30, -45, -27, -15, -36, -40, -16, -41,  12, -18, -24, -20, -39,  -4,  93, -25, -29, -36, -38, -25;
/M: SY='H'; M=  -6, -42, -16,  27, -28, -35,  79,  14,   0, -25, -18,   5, -31,  12,  21, -21, -25, -24, -42,   9;
/M: SY='Q'; M=  -7, -35,  -1, -22,  23, -39, -27,  -4,  -7,  31,  22, -29, -38,  39, -24, -26, -22,  25, -34, -15;
/M: SY='H'; M= -29, -41, -14, -16, -25, -30, 103, -41, -17, -32, -19,  37, -33,  30, -15, -17,  -4, -41, -45,  30;
/M: SY='P'; M= -25, -49, -29, -20, -44,  23, -31, -11,  12, -41, -30, -27,  90, -24,  -3, -23, -23, -35, -40, -40;
/M: SY='N'; M= -24, -39,  33,  20, -40,  16, -16, -38,   3, -18, -29,  44, -31,  29,  20, -15,  -3, -37, -46, -31;
/M: SY='R'; M= -20, -36, -25,   2, -32,  10, -25, -18,   4, -14, -20, -20, -32,  25,  44, -17,  26,  21, -42, -27;
/M: SY='D'; M=  20, -38,  34,  24, -33, -30, -24, -24,  -2,   9, -21, -21,  32,   6,   3, -19, -21, -11, -43, -30;
/M: SY='G'; M= -21, -40,  17,  -2,  20,  51, -25, -39,  -2, -35, -30, -16,   8, -22,  14, -17,   0, -36, -30,  11;
/I:         I=-20; MD=-21;
/M: SY='M'; M=   8, -47,  -3, -30, -44, -37, -33, -34, -28, -32,  50, -33,  41, -29,  11,   5, -28, -34, -52, -38; D=-20;
/I:         I=-20; MI=0; MD=-21; IM=0; DM=-21;
/M: SY='Y'; M= -32,  25, -36, -38,  43,  -9,  -6, -21, -31, -16, -15, -34, -46, -28, -29, -29, -29, -25,   4,  98;
/M: SY='T'; M= -14, -26, -22, -25,   5, -28, -29, -21, -22,  -9, -21, -12, -25, -23, -29,  32,  75, -16, -44, -23;
/M: SY='W'; M= -31,  56, -47, -39,  26, -39,  16, -22, -34, -23, -24, -39, -43, -35, -36, -32,  -5,   2, 128,  34;
/I:         I=-28; MD=-29;
/M: SY='W'; M= -39, -59, -55, -37,  25, -40, -48, -37, -26, -32, -34, -48, -44,   4,  17, -41, -45, -46, 145,   4; D=-28;
/I:         I=-28; MI=-29; MD=-29; IM=-29; DM=-29;
/M: SY='N'; M=  -3, -33,  33, -19, -42,  11, -22, -40, -21, -43, -36,  42, -32, -19, -28,  41,  22, -35, -53, -35; D=-28;
/I:         I=-28; DM=-29;
/M: SY='Y'; M= -26, -38, -29,  -4,  18,  -7, -15, -17, -25, -17,  13, -27, -36,   5, -27, -21,  24,   4,  45,  75;
/M: SY='R'; M= -27, -39,   2, -21, -27,  -8, -20, -20,  -6,  16,  34,   6,   7, -15,  60, -26, -25,  -9, -40, -24;
/M: SY='G'; M=  -5, -36, -26, -25, -35,  46,  10, -32,  11, -16,  31, -16,  10, -19,   3,  20,   1, -30, -40, -29;
/M: SY='N'; M=  -3, -36, -17, -17, -42,  40, -20, -35,  25, -38, -28,  42, -31,  40, -14,   4, -19, -12, -41, -32;
/M: SY='G'; M=  31, -33, -29, -30, -31,  51, -28, -31, -24, -15,  11, -19, -31, -24,  -1,   2,  11, -25, -35,   3;
/I:         I=-26; MI=0; MD=-27; IM=0; DM=-27;
/M: SY='R'; M= -31, -40, -30,   1,  51, -42, -22, -25,  20,   6, -17, -26, -39, -15,  62, -28, -27, -26, -25,  -8;
/M: SY='W'; M= -25, -42,  41, -13, -25, -32,  14,  -5,  -7,   2, -21, -18,  35,  24, -24,   8, -21, -10,  48,  12;
/M: SY='R'; M=  -2, -35,   4, -19, -37,  24, -22, -36,  16, -20, -28,  22, -31, -15,  37,  13,  24, -31, -43, -30;
/M: SY='N'; M= -23,  27,  10, -21, -37,  17, -14, -41,   1, -44, -34,  80, -35, -17, -22,   5, -14, -41,  49, -30;
/M: SY='Y'; M=  -4, -36, -32, -25,  23, -36,  21,  10,   9,   7, -12, -25, -36,  11,   2,  -2,  -1,  10, -25,  38;
/M: SY='G'; M= -14,  26, -29, -37, -42,  79, -34, -43, -28, -43, -34, -16, -33, -29,  -4, -14, -29, -16, -39, -39;
/M: SY='W'; M= -24, -40,  -2, -28, -15, -31, -33, -21,  -4,   4,  50, -28, -35, -23, -27,  23,  -4, -26, 119,  -8;
/M: SY='R'; M= -30, -46, -24,   6, -39, -40, -15, -46,  13, -38, -27, -19, -37,  -2,  93, -24, -28, -39, -39, -26;
/M: SY='I'; M= -27,  26, -48, -44, -10, -51, -42,  65, -41,  37,   2, -41, -41, -37, -43, -37, -22,  19, -38, -20;
/M: SY='D'; M= -31, -44,  98,   6, -51, -27, -16, -49, -18, -47, -47,   2, -30, -17, -26, -19, -20, -46, -66, -33;
/M: SY='Y'; M= -33, -42, -34, -35,  24, -42,  45,   2, -30,   8,  -9, -32, -44, -25, -27, -30, -28, -19,   0,  95;
/M: SY='F'; M= -28, -36, -43, -36,  57, -45,  11,  34, -35,  13,  -7, -35, -41,   6, -35, -31,  -5,  23,  45,  -2;
/M: SY='L'; M=  -3, -30, -44, -37, -10, -44, -35,   7, -37,  54,   2, -40, -42, -34, -37, -30,   2,  37, -39, -20;
/M: SY='V'; M=  36, -28, -32,  -4, -23,  -9, -35,  -4, -29,  17, -11, -29, -34, -27, -33, -16,  15,  36, -42, -27;
/M: SY='S'; M= -10, -30,   1, -20, -31,   2, -23, -33, -21, -36, -30, -10,  13, -17, -27,  61,  38, -27, -40,   8;
/M: SY='R'; M= -25, -43, -18,  16, -40, -32,   4, -38,  36, -19, -26,   6,  37,  34,  43,  -2, -21, -36, -40, -28;
/M: SY='K'; M=   6, -36,  16, -14, -41,  12, -23, -40,  35, -40, -31, -12,   8, -12,  30,  29,   4, -33, -42, -31;
/M: SY='L'; M=   5, -32, -45, -38,  14, -42, -31,  20, -37,  54,  43, -41, -42, -32, -36, -33, -24,   5, -33, -15;
/M: SY='W'; M=  27,  32, -34,  -5, -21, -32, -31, -11,  17,  21,  33, -30, -35, -22, -22, -22, -21,  11,  47, -22;
/I:         I=-21; MI=0; MD=-22; IM=0; DM=-22;
/M: SY='P'; M=   1, -44,  39,  27, -47,  -4, -25, -44,   2, -44, -37, -18,  52, -16,  14,   1, -22, -40, -47, -38; D=-21;
/I:         I=-21; DM=-22;
/M: SY='C'; M=  23,  65, -28, -25, -35, -28, -28, -34,   0, -32,  13,  17, -36,   1,  21,  -2,  13, -27,  36, -30; D=-21;
/I:         I=-21; DM=-22;
/M: SY='V'; M=   8,  24, -37,  -4,   4, -41, -37,  26, -29,  19,  -7, -36, -39, -30,  -3, -27, -19,  44, -40, -22;
/M: SY='W'; M= -21,  26, -17,  34, -33, -35,  10, -23,  30, -28, -24, -19, -28,  23, -13,  -1,  17,  14,  46, -25;
/M: SY='D'; M=  15, -35,  50,   7, -37, -25, -22, -13,  15, -14, -27, -11, -29, -14,   8,  25,   2, -26, -46, -30;
/M: SY='S'; M=  35, -27, -25, -24, -34,   3, -29, -23, -24, -30, -26, -15, -28, -19, -29,  53,  23,   8, -44, -30;
/M: SY='D'; M= -25, -42,  54, -13,  -5,  31, -22, -43,   2, -40, -35,  10,   1, -19,  17,  -6, -24, -41,  52,   2;
/I:         I=-17; MD=-18;
/M: SY='I'; M= -53, -65, -71, -67, -11, -76, -69,  28, -56, -33, -35, -62, -67, -61, -12, -57, -18,   8, -66, -46; D=-17;
/I:         I=-17; MI=0; MD=-18; IM=0; DM=-18;
/M: SY='I'; M=  -3, -37, -32,  -4, -21, -38,  10,  49, -30,  10,  19, -28,  28, -26, -34,  -3,  16,  -1, -40, -23;
/M: SY='W'; M=  -4, -37, -31,   0, -22, -37, -25,   3,   4,  17,  35, -28, -36,  12,  37, -10, -23,  10,  44, -20;
/M: SY='P'; M=  28, -35,   2,   3, -33,   1, -25, -33, -22, -36, -29, -19,  54, -20, -29,  26,  16, -28, -37,  10;
/M: SY='D'; M= -24,  29,  46,  25,  -2,  -3,  17, -34,  15, -15,  10,  11, -31, -14, -19,   8, -19, -33, -45, -25;
/M: SY='F'; M=  -7, -35, -34,   8,  48, -13, -31,  14, -25,  18, -10, -33, -39, -27,  13, -28, -24,  23, -28, -10;
/M: SY='M'; M=  -8,  28, -29,  -4,   5,  -7,  20, -20,  15,   7,  60,  -2, -35, -16,  30, -25, -24, -21, -37, -18;
/M: SY='G'; M= -18, -42,   4, -30, -37,  67, -31, -40, -27, -36,  29, -18,  26, -26,  -6, -18, -29, -39,  52, -30;
/M: SY='S'; M=  -5, -28, -18, -18, -38, -13, -21, -37, -19, -40, -33,  -7, -27,  12, -23,  81,   1, -30, -45, -29;
/M: SY='D'; M= -61, -88, 197,  12,-102, -55, -32, -98, -36, -95, -93,   4, -60, -34, -53, -37, -40, -92,-133, -67;
/M: SY='H'; M= -65, -88, -32, -33, -61, -68, 253, -98, -42, -63, -33, -11, -66, -20, -30, -43, -62, -97,-133,   1;
/M: SY='C'; M=  15, 121, -38, -37, -34, -32, -40, -31, -34, -29, -28, -27, -45, -38, -40,   2,   1,  -5, -56, -40;
/M: SY='P'; M= -29, -53, -31, -19, -46, -32, -32, -33, -26, -40,  14, -36, 109, -29, -38, -27, -22, -38, -42, -43;
/M: SY='V'; M= -20, -33, -47, -42, -14, -49, -47,  51, -39,  11,  -2, -41, -41, -39, -41, -32, -17,  64, -45, -22;
/M: SY='W'; M= -24, -37, -28, -12,  13,  13,  24, -19, -27,  -7, -19,   8, -36, -26, -30, -20,  25,   4,  74,  49;
/M: SY='V'; M=  22, -29, -40, -34, -16, -35, -35,  14, -33,  33,  24, -34, -38, -30, -35,  -5,   2,  37, -41, -23;
/M: SY='D'; M= -22, -38,  47,  34, -26, -34, -23,  18, -21,  -7, -21, -16, -30, -16, -27,  13,   2,   6, -41,   9;
/M: SY='F'; M= -30, -35, -47, -42,  55, -48, -30,  28, -39,  35,  -2, -41, -45, -38, -38, -36, -25,  24, -18,  36;
/M: SY='D'; M=  -6, -39,  54,   9, -43,  -2,  26, -44,  23, -42, -33,  21, -30, -11,  31,   3, -20, -39, -49, -29;
/M: SY='W'; M= -29, -40,   1,  20,   3, -45, -32,  10,  -1,  25, -13, -31, -38, -24,  -2, -30,  -1,   8,  42, -21;
/I:         E1=0; IE=-105; DE=-105;
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Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2014_07 which contains 546'000 sequence entries.


Total number of hits 25 in 25 different sequences
Number of true positive hits 25 in 25 different sequences
Number of 'unknown' hits
Number of false positive hits
Number of false negative sequences 0
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 100.00 %

Comments [info]

Matrix type [info] protein_domain
Scaling database [info] window20
Author [info] PS_Langendijk_Genevaux
Taxonomic range [info] Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 1
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
25 sequences

APEA_DICDI  (P51173), APEX1_BOVIN (P23196), APEX1_DANRE (A0MTA1), 
APEX1_GORGO (A1YES6), APEX1_HUMAN (P27695), APEX1_MOUSE (P28352), 
APEX1_PANPA (A1YFZ3), APEX1_PANTR (A2T6Y4), APEX1_PONPY (A2T7I6), 
APEX1_RAT   (P43138), APEX2_BOVIN (Q5E9N9), APEX2_HUMAN (Q9UBZ4), 
APEX2_MOUSE (Q68G58), APEX_ARATH  (Q5XF07), APN2_SCHPO  (P87175), 
APN2_YEAST  (P38207), ARP_ARATH   (P45951), EX3_ECOLI   (P09030), 
EX3_HAEIN   (P44318), EX3_SALTI   (P0A1B0), EX3_SALTY   (P0A1A9), 
EXOA_BACSU  (P37454), EXOA_STRPN  (P0A2X3), EXOA_STRR6  (P0A2X4), 
RRP1_DROME  (P27864)
» More

PDB
[Detailed view]
13 PDB

1AKO; 1BIX; 1DE8; 1DE9; 1DEW; 1E9N; 1HD7; 2ISI; 2O3C; 2O3H; 3U8U; 4IEM; 4LND
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View entry in original PROSITE format
View entry in raw text format (no links)
Direct ScanProsite submission