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| Entry: PS51448 |
General information about the entry
| Entry name [info] | P_TREFOIL_2 |
| Accession [info] | PS51448 |
| Entry type [info] | MATRIX |
| Date [info] | 01-MAY-2009 CREATED; 10-MAY-2017 DATA UPDATE; 05-JUL-2017 INFO UPDATE. |
| PROSITE Doc. [info] | PDOC00024 |
| Associated ProRule [info] | PRU00779 |
Name and characterization of the entry
| Description [info] | P-type 'Trefoil' domain profile. |
| Matrix / Profile [info] |
/GENERAL_SPEC: ALPHABET='ABCDEFGHIKLMNPQRSTVWYZ'; LENGTH=44; /DISJOINT: DEFINITION=PROTECT; N1=5; N2=40; /NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=3.2270780; R2=0.0119778; TEXT='NScore'; /NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=1962.0344238; R2=2.7503076; PRIORITY=1; TEXT='Heuristic 5.0%'; /CUT_OFF: LEVEL=0; SCORE=441; H_SCORE=3175; N_SCORE=8.5; MODE=1; TEXT='!'; /CUT_OFF: LEVEL=-1; SCORE=274; H_SCORE=2716; N_SCORE=6.5; MODE=1; TEXT='?'; /DEFAULT: M0=-23; D=-50; I=-50; B1=-500; E1=-500; MI=-105; MD=-105; IM=-105; DM=-105; ... A B C D E F G H I K L M N P Q R S T V W Y Z /I: B1=0; BI=-105; BD=-105; /M: SY='S'; M= -1, -9,-41,-10,-11,-40,-19,-20,-41,-12,-39,-28, -5,-23, -9,-22, 4, -6,-29,-48,-34,-11; /M: SY='T'; M= -4,-12,-39,-16, -4,-42,-27,-16,-34, -1,-33,-19, -5,-26, 3,-10, 7, 8,-21,-53,-34, -3; /M: SY='C'; M=-10,-58, 95,-66,-62,-36,-58,-63,-12,-53,-23,-23,-49,-55,-43,-54,-21,-18,-10,-46,-45,-61; /M: SY='S'; M= 2,-11,-37,-16,-12,-42,-19,-18,-39, -8,-36,-25, -3,-14, -8,-20, 14, 0,-28,-56,-34,-11; /I: I=-10; MI=0; MD=-21; IM=0; DM=-21; /M: SY='V'; M=-13,-42,-20,-45,-32,-18,-48,-32, 10,-28, -4, 1,-36,-35,-27,-28,-21, -4, 21,-44,-25,-31; D=-10; /I: I=-10; DM=-21; /M: SY='P'; M= -8,-12,-45, -8, -3,-49,-35,-24,-42, -8,-39,-27,-12, 9, -6,-18, -6, -8,-30,-60,-45, -4; /M: M= -2,-21,-42,-18, -8,-42,-34,-26,-30,-11,-31,-21,-22, -2, -9,-20, -7,-11,-18,-56,-41, -8; /M: SY='S'; M= -2, -2,-41, -7, -6,-41,-20,-15,-42, -4,-39,-27, 4,-29, -5,-12, 12, -3,-31,-53,-34, -6; /M: SY='E'; M=-11, 0,-52, 4, 14,-46,-31, -9,-46, 0,-45,-30, -4,-21, 5,-12, -5, -8,-32,-55,-36, 10; /M: SY='R'; M=-27,-19,-60,-29, -8,-48,-39, 3,-50, 33,-40,-31, -9,-27, 10, 74,-19,-19,-40,-50,-35, 0; /M: SY='I'; M=-23,-48,-32,-52,-36, -7,-58,-35, 17,-29, 3, 4,-43,-43,-24,-30,-29,-16, 16,-41,-18,-33; /M: SY='D'; M=-18, 27,-58, 43, 13,-56,-27,-16,-58,-11,-58,-43, 13,-15, -1,-22, -4,-12,-47,-69,-51, 7; /M: SY='C'; M=-10,-59,126,-69,-69,-40,-60,-68,-21,-58,-30,-30,-49,-59,-49,-57,-20,-20,-20,-50,-50,-68; /I: I=-12; MD=-25; /M: SY='G'; M= -2,-29,-48,-37,-39,-29, 33,-26,-46,-29,-44,-32,-21,-45,-34,-37,-11,-23,-39,-43,-26,-37; D=-12; /I: I=-12; MD=-25; /M: SY='P'; M=-20,-36,-50,-36,-28,-12,-41,-13,-37,-26,-33,-28,-32, 5,-27,-32,-20,-24,-31,-27, -2,-27; D=-12; /I: I=-12; MI=0; MD=-25; IM=0; DM=-25; /M: SY='P'; M=-12,-24,-47,-23,-16,-40,-40,-22,-33,-17,-35,-26,-19, 14,-16,-23,-11,-16,-24,-51,-36,-16; /M: SY='G'; M= -8, -2,-59, -3,-18,-58, 36,-27,-65,-18,-64,-47, 1,-31,-23,-27, -6,-23,-54,-64,-55,-20; /I: I=-14; MI=0; MD=-29; IM=0; DM=-29; /M: SY='I'; M= -9,-41,-24,-47,-38,-25,-47,-44, 23,-33, -4, 2,-38,-34,-33,-37,-15, -5, 20,-52,-33,-38; /M: SY='T'; M= 1, 4,-27, -8,-12,-44,-21,-20,-34, -8,-39,-22, 16,-28, -8,-19, 32, 44,-19,-57,-33,-13; /M: SY='Q'; M= -7,-14,-51,-12, 14,-47,-35,-13,-45, 14,-42,-26,-14, -4, 16, -1, -8,-12,-32,-55,-41, 14; /M: SY='E'; M= -3, 5,-50, 11, 17,-51,-22,-10,-50, 2,-49,-33, -1,-25, 11,-12, 2, -8,-36,-59,-42, 14; /M: SY='E'; M=-12, -6,-45, -4, 14,-47,-28,-13,-41, -5,-40,-25, -8,-30, 12,-17, -6, -8,-30,-55,-40, 12; /M: SY='C'; M=-10,-60,126,-70,-69,-39,-60,-69,-18,-59,-29,-29,-50,-59,-50,-59,-20,-19,-18,-50,-49,-69; /M: SY='E'; M=-14,-11,-48,-11, 11,-42,-39,-10,-33, -1,-33,-21,-12,-30, 9, -6,-11, -7,-22,-52,-35, 9; /M: SY='Q'; M= 5,-12,-41,-14, 4,-46,-20,-16,-41, 1,-40,-25, -9,-26, 8,-11, 2, -9,-27,-50,-38, 4; /M: SY='R'; M=-23,-27,-50,-36,-16,-38,-43,-10,-28, 17,-23,-15,-18,-32, 2, 39,-19,-16,-24,-49,-34, -9; /M: SY='G'; M= -7, -9,-56,-19,-26,-55, 44,-25,-62,-15,-60,-43, 4,-40,-22,-24, -5,-21,-52,-59,-49,-25; /M: SY='C'; M=-11,-59,122,-69,-68,-38,-59,-66,-21,-56,-30,-30,-49,-59,-48,-58,-20,-20,-21,-48,-46,-68; /M: SY='C'; M=-13,-60,106,-70,-68,-35,-61,-68, -8,-58,-21,-21,-51,-58,-49,-58,-23,-20,-11,-50,-47,-67; /M: SY='W'; M=-41,-64,-39,-67,-56, 33,-59,-16,-33,-51,-24,-22,-56,-63,-39,-47,-42,-39,-35, 69, 47,-49; /I: I=-12; MI=0; MD=-25; IM=0; DM=-25; /M: SY='D'; M=-19, 35,-56, 49, 12,-55,-26,-11,-58,-10,-58,-45, 23,-30, -2,-20, 2, -9,-46,-69,-48, 7; /M: SY='P'; M= -2, -8,-48, -7,-11,-53,-14,-25,-51,-14,-50,-37, -5, 16,-15,-25, 5,-13,-40,-64,-49,-12; /M: SY='S'; M= -3,-12,-30,-21,-13,-35,-27,-20,-29,-10,-31,-19, -2,-31, -6,-18, 15, 11,-19,-48,-29,-12; /I: I=-5; MD=-9; /M: SY='S'; M= -8,-17,-34,-22,-15,-25,-23,-18,-23,-12,-25,-12,-11,-24, -8,-20, 1, -4,-18,-43,-24,-14; D=-5; /I: I=-5; MI=0; MD=-9; IM=0; DM=-9; /M: SY='S'; M= -3,-14,-32,-18,-12,-26,-22,-10,-28, -5,-26,-17, -8,-14, -6,-12, 1, -2,-19,-40,-21,-10; D=-5; /I: I=-5; DM=-9; /M: SY='N'; M= -9, 7,-45, 1, -9,-47, 12,-15,-50, -7,-49,-35, 16,-25,-12,-16, -1,-10,-40,-53,-41,-11; D=-5; /I: I=-5; DM=-9; /M: SY='V'; M= 4,-34,-21,-36,-24,-23,-30,-29, 1,-22,-10, -5,-29,-24,-23,-28, -8, 1, 14,-41,-25,-24; D=-5; /I: I=-5; DM=-9; /M: SY='P'; M=-11,-33,-45,-28,-19,-42,-43,-32,-28,-16,-32,-25,-32, 65,-24,-24,-18,-20,-22,-54,-43,-19; D=-5; /I: I=-5; DM=-9; /M: SY='W'; M=-27,-47,-42,-48,-32, -9,-43,-18,-38,-31,-31,-24,-40,-37,-21,-25,-29,-29,-35, 55, 9,-27; D=-5; /I: I=-5; DM=-9; /M: SY='C'; M=-10,-60,126,-70,-69,-40,-60,-70,-19,-60,-29,-29,-50,-60,-50,-60,-20,-20,-18,-50,-50,-69; /M: SY='Y'; M=-38,-54,-44,-59,-53, 62,-59, 5,-18,-43, -9,-14,-48,-58,-38,-43,-33,-33,-23, 10, 69,-48; /M: SY='Y'; M=-35,-39,-49,-46,-36, 31,-53, 15,-28,-28,-21,-20,-31,-48,-20,-28,-28,-29,-29, -7, 45,-31; /M: SY='P'; M= -9,-23,-54,-24,-17,-53,-16,-27,-49, -6,-47,-35,-16, 26,-16,-17, -8,-17,-38,-62,-49,-16; /M: SY='K'; M=-11, -7,-48,-11, -6,-46,-27,-16,-42, 7,-39,-27, 0,-19, -2, -7, -5, -6,-31,-54,-39, -5; /I: E1=0; IE=-105; DE=-105;» more |
Numerical results [info]
| Total number of hits | 69 in 44 different sequences |
| Number of true positive hits | 69 in 44 different sequences |
| Number of 'unknown' hits | 0 |
| Number of false positive hits | 0 |
| Number of false negative sequences | 6 |
| Number of 'partial' sequences | 0 |
| Precision (true positives / (true positives + false positives)) | 100.00 % |
| Recall (true positives / (true positives + false negatives)) | 92.00 % |
Comments [info]
| Matrix type [info] | protein_domain |
| Scaling database [info] | reversed |
| Author [info] | CJA_Sigrist |
| Taxonomic range [info] | Eukaryotes |
| Maximum number of repetitions [info] | 6 |
| Feature key [info] | DOMAIN |
| Feature description [info] | P-type |
| Version [info] | 4 |
Cross-references [info]
| UniProtKB/Swiss-Prot True positive sequences |
44 sequences
LYAG_BOVIN (Q9MYM4 ), LYAG_HUMAN (P10253 ), LYAG_MOUSE (P70699 ), LYAG_PONAB (Q5R7A9 ), LYAG_RAT (Q6P7A9 ), MGAL_HUMAN (Q2M2H8 ), MGA_HUMAN (O43451 ), MLRP1_ACRMI (B3EWZ5 ), MLRP2_ACRMI (B3EWZ6 ), MUA1_XENLA (P10667 ), MUC1_XENLA (Q05049 ), SUIS_HUMAN (P14410 ), SUIS_RABIT (P07768 ), SUIS_RAT (P23739 ), SUIS_SUNMU (O62653 ), TFF1_CANLF (Q863T4 ), TFF1_HUMAN (P04155 ), TFF1_MOUSE (Q08423 ), TFF1_RAT (Q63467 ), TFF2_CANLF (Q863J2 ), TFF2_HUMAN (Q03403 ), TFF2_MOUSE (Q03404 ), TFF2_PIG (P01359 ), TFF2_RAT (Q09030 ), TFF3_BOVIN (A8YXX7 ), TFF3_CANLF (Q863B4 ), TFF3_FELCA (B4X8D9 ), TFF3_HUMAN (Q07654 ), TFF3_MOUSE (Q62395 ), TFF3_PIG (Q29183 ), TFF3_RAT (Q03191 ), XP1_XENLA (Q00222 ), XP2_XENLA (P17437 ), XP4_XENLA (Q00223 ), ZP1_HUMAN (P60852 ), ZP1_MOUSE (Q62005 ), ZP1_RABIT (I6M4H4 ), ZP1_RAT (O54766 ), ZP4_BOVIN (Q9BH11 ), ZP4_FELCA (P48834 ), ZP4_HUMAN (Q12836 ), ZP4_PIG (Q07287 ), ZP4_RABIT (Q00193 ), ZP4_RAT (Q8CH34 )» more
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| UniProtKB/Swiss-Prot False negative sequences |
6 sequences
FMR1N_HUMAN (Q8N0W7 ), FMR1N_MOUSE (Q80ZA7 ), TM190_BOVIN (E1BJD3 ), TM190_CANLF (E2R0A5 ), TM190_HUMAN (Q8WZ59 ), TM190_MOUSE (Q9D2E9 )» more |
| PDB [Detailed view] |
22 PDB
1E9T; 1HI7; 1PCP; 1PE3; 1POS; 1PS2; 1PSP; 2PSP; 2QLY; 2QMJ; 3CTT; 3L4T; 3L4U; 3L4V; 3L4W; 3L4X; 3L4Y; 3L4Z; 3LPO; 3LPP; 3TON; 3TOP » more |
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