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PROSITE entry PS51489


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General information about the entry

Entry name [info] BUB1_N
Accession [info] PS51489
Entry type [info] MATRIX
Date [info] 01-JUN-2010 CREATED;
13-FEB-2019 DATA UPDATE;
24-JAN-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC51489
Associated ProRule [info] PRU00822

Name and characterization of the entry

Description [info] BUB1 N-terminal domain profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=159;
/DISJOINT: DEFINITION=PROTECT; N1=6; N2=154;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=1.9407294; R2=0.0075440; TEXT='NScore';
/NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=35237.0000000; R2=0.0000000; PRIORITY=1; TEXT='Heuristic 5.0%';
/CUT_OFF: LEVEL=0; SCORE=1533; H_SCORE=35237; N_SCORE=13.5; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=605; H_SCORE=35237; N_SCORE=6.5; MODE=1; TEXT='?';
/DEFAULT: M0=-23; D=-100; I=-100; B1=-1000; E1=-1000; MI=-255; MD=-255; IM=-255; DM=-255;
...
                A    C    D    E    F    G    H    I    K    L    M    N    P    Q    R    S    T    V    W    Y
/I:         B1=0; BI=-255; BD=-255;
/M: SY='F';  M=   0, -61, -33, -35,  70, -64,   2, -35, -33,  34,  13, -61,  -4, -27, -57, -55, -51, -10,  62,  31;
/M: SY='E';  M= -29,  15,  26,  77, -57, -11, -47,  10, -39, -24, -51, -45, -51,  -5, -47,  -7, -47, -21,  36, -11;
/M: SY='E';  M=  25, -58,   7,  44, -29, -49,  16, -34, -21,  -2, -48,  14, -53, -37, -24,  41,  -1, -49, -64,   3;
/M: SY='E';  M=  30, -64,  44,  55, -68, -52,  20, -41,  -1, -62, -56, -40,  33,   9,   0,  -2, -44, -57, -69, -56;
/M: SY='I';  M= -52, -61, -68, -59,  -9, -72, -59,  62, -33,  50,  21, -62, -65,  19, -12, -58, -48,  15, -60, -42;
/M: SY='R';  M=   9, -65, -40,  34, -63, -22,  -5, -63,  28, -36, -51,  16,  19,  43,  52, -20, -46, -59, -63, -17;
/I:         I=-30; MD=-77;
/M: SY='S';  M=  13, -62,  23,   8, -29, -31, -54,  11, -48, -37,  14,   4, -59,  -9,  -2,  27,   8,   8, -72, -55; D=-30;
/I:         I=-30; MI=-77; IM=-77; DM=-77;
/M: SY='Y';  M= -29, -64, -51,  16, -26, -13, -37, -21,  21,  10,  29, -27, -15, -43, -44, -34, -26, -46, -36,  93;
/M: SY='D';  M=   2, -59,  59,  -4, -62, -49, -46, -26,  -5, -27, -53, -34, -53,  41, -45,  46,  33, -52,   9, -53;
/I:         I=-15; MD=-39;
/M: SY='G';  M=   2, -66, -12,   5, -73,  67, -58, -73, -54, -73, -64, -15,  29, -51, -62,  17, -17, -67, -70, -67; D=-15;
/I:         I=-15; MD=-39;
/M: SY='D';  M= -53, -70,  54,  16, -69, -58,  -3, -66, -12, -26,  10,  12,  17, -44,  13,  30, -28, -65, -80, -60; D=-15;
/I:         I=-15; MI=0; MD=-39; IM=0; DM=-39;
/M: SY='D';  M= -55, -68, 110,   4, -75, -52, -40, -73, -15, -71, -69,   7, -54, -40, -48, -43, -44, -70, -88, -58;
/M: SY='P';  M= -35, -77, -54, -43, -72, -56, -56, -60, -19, -69, -57, -59, 119, -52, -11, -50, -46, -39, -67, -68;
/M: SY='L';  M= -54, -57, -72, -65,   8, -74, -58,  27, -66,  79, -18, -70, -70, -60, -63, -64, -50,  -3, -57, -39;
/M: SY='Q';  M= -18, -64,  59,  39, -62, -17, -43, -55, -38,   5, -48, -38, -54,  63, -10,   0,  -8, -28, -69, -53;
/M: SY='P';  M=  -2, -63, -30, -26, -46, -21,  -3,   4, -56,  32, -35, -30,  72, -54, -60, -51, -46,  32, -63,  -2;
/M: SY='W';  M= -62,  -1, -77, -66,  31, -63, -58, -53, -58, -49, -51, -73, -69, -58, -59, -64, -65, -62, 154,  78;
/M: SY='L';  M= -52,  19,  21,  -9, -12, -64,  -5,   5, -55,  51, -31, -23, -65, -18, -56,  -7, -48,  -5,  40,  46;
/M: SY='R';  M= -31, -65,  26,  47, -65, -55,   3, -66,  14, -33, -54,   4, -54,   8,  64,  24, -44, -61, -68, -53;
/I:         I=-30; MD=-77;
/M: SY='Y';  M= -56,  -7, -61, -63,  50, -11, -35, -46, -57, -18, -41, -58, -71, -54, -55,  -2, -52, -50, -25, 109; D=-30;
/I:         I=-30; MI=-77; IM=-77; DM=-77;
/M: SY='I';  M= -50, -62, -73, -70, -36, -76, -71,  90, -65,  10,   6, -65, -63, -62, -68, -60, -45,  36, -63, -44;
/M: SY='K';  M= -47,  51, -13, -17, -59, -54,   4, -31,  61, -25, -49,  34, -56,  34,   8,  13, -16, -39, -65, -13;
/M: SY='W';  M= -59, -79, -73, -59,   5, -20,  36, -59,   8, -26, -54, -65, -64, -52, -10, -62, -66, -68, 159, -20;
/M: SY='I';  M=   3, -56, -62, -58, -11, -64, -57,  47, -56,  27,  38, -54, -59,  -1, -58, -46,  46,  21, -61,  -8;
/M: SY='E';  M= -48, -16, -35,  68,  -6, -60,  12, -34,   4,  -8,  46,  21, -53,  28,  -9, -23, -46,  -5, -65, -48;
/M: SY='Q';  M= -48, -66,  50,  54, -67, -29,  26, -65,  -4, -63, -55,  28, -52,  66, -19, -17, -20, -39, -70, -22;
/M: SY='H';  M=   7,  24, -40,   4, -55, -47,  57, -57, -10, -26, -13,  54, -56, -39,  -5,  43,  18, -53, -69,   4;
/M: SY='Y';  M= -26, -62, -60, -27,  56, -38,  22, -38, -29,  27,  20, -56, -66, -12,  -9, -53, -22, -43, -35,  81;
/M: SY='P';  M= -23, -71, -52, -44, -67,  -7,  -3, -30, -12, -64, -10, -16, 107, -50, -21, -21,  -6, -36, -67, -63;
/M: SY='Q';  M=  11, -60, -17,  14, -62,   1, -49, -27, -24, -19, -48, -41,  32,  56, -46,  23,  46, -49, -66, -55;
/I:         I=-20; MD=-50;
/M: SY='G';  M= -45, -85, -75, -82, -88,  67, -80, -87, -42, -47, -79, -63, -31, -75, -83, -28, -74, -46, -85, -85; D=-20;
/I:         I=-20; MI=0; MD=-50; IM=0; DM=-50;
/M: SY='S';  M= -20, -79,  -8, -10, -84, -43, -70, -79, -65, -38, -74, -13, -75,  13, -71,  30,  24, -74, -93, -77; D=-20;
/I:         I=-20; DM=-50;
/M: SY='K';  M=  12,   2,   3,   7, -59,  -8, -48, -53,  46,  -2, -14,  -2,  23,  -7,  24, -13, -19, -22, -65, -55;
/M: SY='Q';  M= -26,  41,   5,  29, -63, -29, -45, -58,  43, -14, -49, -39, -53,  62, -34,  25,   4, -38, -66, -54;
/M: SY='S';  M=  -1, -60,  21,  19, -64,  -2, -45, -59,  -1, -38, -53, -37, -53,  47,  19,  58, -20, -24, -67, -54;
/M: SY='G';  M= -24, -63,   9,  -3, -60,  47,  42, -60,  26, -27, -51,  25, -56,   3,  18, -24, -20, -16, -65, -13;
/M: SY='L';  M= -53, -59, -66, -58,   0, -69, -51,  11, -32,  68,  40, -19, -68,   6, -16, -59, -49,  -8, -55,  11;
/M: SY='Q';  M= -48, -61, -55, -46,  25, -61, -50,  -8,   2,  24,   0, -14,  30,  51,   8,   5, -12,  17, -59, -43;
/M: SY='D';  M=  -3,  -2,  33,  14, -60, -54,  14, -13,  -8, -29, -49,  -8,  32, -40,  32,  17,  22,  -5, -71, -54;
/M: SY='L';  M= -18,   5, -68, -63,  28, -69, -58,  19, -62,  52, -26, -63, -67, -60, -62, -54,   7,  40, -55,  21;
/M: SY='L';  M= -53,  19, -71, -64, -29, -71, -53,   3, -63,  73,  56, -67, -69, -57, -61, -62, -49,   0, -56,  18;
/M: SY='E';  M= -48, -67,  -6,  89, -60, -62, -41, -63,  -4, -34,  -2, -43, -47,  29,  -3, -43,   5, -59, -62,  11;
/M: SY='R';  M= -30, -66, -43,  22, -65, -59,   0, -66,  33, -61, -52, -40, -55,  31,  84, -10,  11, -60, -64, -51;
/M: SY='C';  M=  -5, 131, -63, -63, -55,  -6, -64, -27, -60,  -1, -49, -52, -70, -63, -66,  -5,   3, -47, -78, -62;
/M: SY='I';  M=   4, -56, -62, -60, -41, -65, -63,  59, -58,  23,   3, -54, -58, -57, -61, -45,  54,  28, -66, -47;
/M: SY='R';  M=   1, -62, -14,  10, -61, -32, -44, -30,  26, -24, -12, -10, -55,  42,  58,   4,  25, -52, -65, -52;
/M: SY='Y';  M=   7, -61, -12,  22,  -2, -55,  10, -53,  37, -29, -47,   1, -55, -11,   7,  -5,  25, -28, -51,  57;
/M: SY='F';  M= -22,  -7, -71, -67,  96, -67, -53,  12, -63,  19, -34, -63, -70, -66, -62, -25, -51, -36, -35,  38;
/I:         I=-22; MD=-57;
/M: SY='Q';  M= -11, -64, -47,  33, -57,   5, -49, -11,  35,  16,   8, -48, -57,  50, -22, -19, -48,  -8, -64, -53; D=-22;
/I:         I=-22; MI=0; MD=-57; IM=0; DM=-57;
/M: SY='D';  M= -50, -63,  71,   6, -61, -17,  22, -62,  18, -20, -54,  35, -55,  -5,   5, -11,  18, -60, -72, -10;
/M: SY='D';  M= -50,   1,  70,  -8, -52, -57,  16, -25, -22,  18,  13,  22, -59,   2, -19, -12, -25,   8, -72, -15;
/M: SY='E';  M= -19, -67,  -3,  66, -57, -32, -44, -60,  19, -16, -52, -45,  47, -33,  16,  -3, -30, -58, -60,  19;
/M: SY='R';  M= -51, -66, -45,  18, -21, -28,  50,  -2,   5, -29, -46,   2, -58,  21,  75, -45,   2, -30, -65, -46;
/M: SY='Y';  M= -59, -69, -60, -62,  19, -66, -28, -17, -54, -16, -36, -61, -71, -50, -52, -55, -53, -46,  29, 123;
/M: SY='R';  M= -27, -63, -46, -38, -58, -56,  51, -60,  57, -14, -47, -15, -56,   9,  60,  17,   2, -57, -64, -17;
/M: SY='N';  M= -49, -59,  41, -19, -66, -24,  36, -64, -37, -66, -55,  93, -57,  40, -43, -19,  16, -64, -80, -54;
/M: SY='D';  M= -55, -68, 112, -19, -75, -51, -40, -73, -41, -71, -69,   2, -55,   3, -50, -42, -45, -70, -89, -58;
/M: SY='P';  M= -16, -65, -14,  31, -56, -32,  18,  -2, -45, -11,  24, -53,  72, -45,   4, -25, -45,  26, -68, -54;
/M: SY='R';  M= -54, -69, -51, -40, -61, -65, -41, -66, -13, -28, -49, -44, -63, -29, 109, -48, -18, -61, -63, -50;
/M: SY='Y';  M= -58, -64, -64, -64,  60, -67, -35, -36, -57,  10,  20, -62, -71, -55, -55, -57, -52, -13, -24, 107;
/M: SY='L';  M= -50, -57, -72, -65, -32, -74, -62,  36, -65,  68, -20, -69, -69, -61, -64, -61, -47,  45, -63, -43;
/M: SY='K';  M= -49, -65,  -9, -34, -65, -12, -43, -62,  73, -62, -52,  15, -55,  29,  59, -43, -18, -21, -64, -53;
/M: SY='I';  M= -33,   1, -66, -64,  -9, -70,  -1,  55, -61,  42, -26, -16, -65, -59, -62, -55,  -3,  38, -60,  10;
/M: SY='W';  M= -23,  79, -83, -67,  -9, -61, -83, -61, -60, -57, -59, -75, -68, -61, -64, -63, -67, -68, 163, -22;
/M: SY='I';  M= -33, -60, -72, -67,   8, -73, -61,  69, -65,  55,  41, -66, -66, -60, -64, -61, -48,  -9, -58, -40;
/M: SY='W';  M=  -6, -64, -48,  10, -53, -57, -17, -52,  54,  11,  -7, -45, -55,  56,  -2, -21,   1, -53,  79, -44;
/M: SY='Y';  M= -58,   2, -61, -61,  36, -67, -32, -39, -26,  17, -34, -61, -71, -52, -52, -56, -53, -45, -22, 114;
/M: SY='A';  M=  66,  18, -59, -53, -53, -31, -58,  38, -53, -39,  45, -52, -56,   1, -56, -37,   8,  -3, -64, -52;
/M: SY='D';  M= -29,  17,  67,  52, -64, -18, -41, -69,   1, -66, -60,  32, -26, -34,  25, -21, -45, -64, -70,  -1;
/M: SY='Y';  M=  -7,  30, -58, -53, -10, -60, -46, -35,  -4,  36,  48,  -1, -63,  16, -50, -14,  -2,  -5,  24,  53;
/M: SY='C';  M= -10,  71, -59, -26,  43, -61, -54,  19, -25,  -9,  18, -19, -63,  19, -55,  -5,   7,  18, -56,   9;
/M: SY='S';  M=   1, -57,  20,   0, -53, -22, -43, -51,  -9, -23,  11,  47, -21, -40, -27,  51,   4, -13, -65,  18;
/I:         I=-13; MI=0; MD=-33; IM=0; DM=-33;
/M: SY='D';  M= -34, -71,  76,  48, -77, -59, -49, -72, -22, -72, -68, -38, -17,   9, -51,  16, -29, -42, -82, -64; D=-13;
/I:         I=-13; MI=0; MD=-33; IM=0; DM=-33;
/M: SY='P';  M=   8,   3, -52, -41, -22, -53, -53, -57,  17, -63, -53, -51,  96,  17,  -6,  -3,  -8, -30, -64, -59;
/M: SY='R';  M=  -1,   0,   1,   2,  -8,   0,  15,  28,  12, -10,   2, -46, -58,  -7,  40, -16, -21,  -3, -64, -47;
/M: SY='D';  M= -15, -64,  63,  60, -10, -54,   2, -60, -15, -59,  -8,  39, -52,  22, -43, -23, -44, -19, -72, -52;
/M: SY='I';  M= -26,   0, -63, -18,  17, -68, -58,  52, -58,  20,  35, -58, -61, -57, -61, -51,  31,  32, -58,  11;
/M: SY='F';  M= -25, -62, -69, -67,  92, -68, -46,   7, -62,   3, -35, -63, -71, -64, -60, -58, -53, -38,  21,  75;
/M: SY='Q';  M=  -6,   2,  14,  19, -57, -54, -46, -22,  39, -15, -12, -17, -54,  45, -17,  28,  -7,   0, -64, -11;
/M: SY='Y';  M= -56, -64, -54,  12,  72, -65,  15, -43, -14,  -7, -39, -54, -64,  28, -18, -52, -25, -26, -33,  80;
/M: SY='M';  M= -29, -57, -69, -60, -31, -68, -49, -23, -18,  68,  91, -64, -66, -52, -55, -60, -49, -30, -57,   7;
/M: SY='Y';  M=   1,  -1,  -5,  29,  16, -60,  39,  -2, -44,  -9,  -7, -49, -60,  14,   9, -17, -48, -27, -45,  71;
/M: SY='N';  M=  18, -60,   0,  -3, -62, -10,  40, -58,   7, -36,  -8,  43, -56,  28,  35,  25, -41, -25, -69, -51;
/M: SY='Q';  M= -28, -64,   9, -35, -61, -18,  43, -22,  49, -12, -47,  47, -57,  53,  30, -42, -46, -57, -67, -49;
/M: SY='G';  M= -52,-124,  19,   9,-127,  67,  42,-131,  26,-127,-117,   3,-115,   6,  34,   8,-108,-126,-127,-115;
/M: SY='I';  M=-110,   3,-132,-129, -98,-135,-130, 102,-125, -28,  21,-123,-122,-122,-127,-118, -30,  37,-124,-105;
/I:         I=-30; MD=-77;
/M: SY='G';  M= -40,  29,-115,-123,  -6, 100,-119,-135,-118,-130,-122,-101,-119,   0,-124,-100,-116,-129,-122,-121; D=-30;
/I:         I=-30; MI=-77; IM=-77; DM=-77;
/M: SY='T';  M=  -8, -57, -23, -14, -28, -56,  -3, -46,  -8,  -3, -44, -20, -55,  22,  44,   8,  62,   2, -68, -49;
/M: SY='Q';  M= -21, -63, -19,  14, -61,  -1, -42, -57,  46, -33,  21,  21, -55,  51,  36,   0, -45, -22, -63, -21;
/M: SY='H';  M= -49,  43, -61, -57,  38, -65,  50, -30, -56,  39,  14, -53, -65, -21, -27,  -3,  13,  28, -59,  -8;
/M: SY='A';  M=  66, -52, -52, -47, -10, -41, -53, -52, -47, -56, -51, -44,  16, -44, -10,  56,  -6, -18, -64, -54;
/M: SY='L';  M=   5,  -5, -21,  22, -41, -22,  14,  -2, -14,  56, -30, -54, -20, -19, -53, -31, -11, -37, -61, -11;
/M: SY='F';  M= -58, -60, -70, -66,  91, -68, -48, -15, -62,  34,   7, -63, -71, -63, -60, -20, -52, -38, -33,  57;
/M: SY='Y';  M= -59, -71, -59, -61,  -9, -65,  20, -46, -53, -43, -39, -59, -70, -48, -50, -54, -55, -52,  73, 124;
/M: SY='E';  M= -48,  18, -10,  74, -55, -65, -50,  44, -10, -43,  15,  -8, -51,  -9, -47, -47,  -8,   6, -68, -54;
/M: SY='E';  M=  34, -59,  10,  44, -63,   8, -47, -18, -39, -28, -51,  -5, -52,  31,  -2,  25,   1, -50, -67, -56;
/I:         I=-30; MD=-77;
/M: SY='W';  M= -24, -74, -74, -65,  38, -65,  -5, -49, -59,  -2, -46, -70, -70, -58, -34, -62, -63, -56, 139,  73; D=-30;
/I:         I=-30; MI=-77; IM=-77; DM=-77;
/M: SY='A';  M=  83,   9, -51, -48, -63,  -1, -54, -55, -49, -57, -51,  18, -55, -46, -54,   8, -21, -44, -65, -59;
/M: SY='W';  M=   2, -60, -44,  20, -50, -29,  -4, -33,   2, -20, -47,  12, -55,  41,   0,  22,  27, -17,  50,  29;
/M: SY='Y';  M= -52,   2, -61, -18,  36, -67,  -2,  12, -56,  38, -31, -32, -66,   7, -56, -28, -24,  21,  29,  59;
/M: SY='Y';  M=  -6,   4, -63, -16,  11, -67,  -4, -30, -57,  63,   2, -62, -68, -52, -22, -56, -50, -35, -45,  64;
/M: SY='E';  M= -13,  33,  18,  92,  -5, -62, -44, -22, -35, -57, -55, -45, -48, -29, -44, -45, -47, -31, -64,  -9;
/M: SY='S';  M=   9, -59, -18,  -3,  -7,  -6,   0,  -4,  26, -23, -48,  11,  -4,  23,  -7,  41,   4, -49, -64, -50;
/M: SY='Q';  M= -10,   1,  -3,   8, -57, -26, -45, -12,  33,   0,  35, -22, -56,  50,  39,   8, -45, -49, -64, -50;
/M: SY='G';  M= -16, -62,   1,  30, -65,  61,  18, -60,  26, -62, -55,  15, -53, -10, -44, -39, -13,  -2, -67, -57;
/I:         I=-30; MI=0; MD=-77; IM=0; DM=-77;
/M: SY='N';  M=  -3, -63,  47,  22, -24, -52,  16, -61,  24, -20, -52,  52,  -3,  -4,  32, -42, -45, -59, -68, -22;
/M: SY='Y';  M= -54, -62, -64, -61,  57, -33, -47,   5, -35,  24,  23, -59, -11, -55,  -9, -32,   1,  -6,  40,  66;
/M: SY='Q';  M= -32, -63, -42,  18, -64,   9, -45, -58,  43, -22, -50,  11,   8,  56,  20,   4,   7, -29, -64, -54;
/M: SY='Q';  M= -17,  -1,  18,  42, -13, -13,   0, -65,  46, -61, -53, -12, -53,  47,  17,  -1, -46, -61, -60,   7;
/M: SY='A';  M=  84, -49, -53, -48, -61, -38, -56, -22, -49, -54, -49, -46, -53, -45, -54,  29,   6, -40, -65, -57;
/M: SY='D';  M= -24, -62,  56,  35, -52, -16,  12,   2, -22,  12, -44,   8, -57, -41, -19,  -1, -44,   6, -68,   1;
/M: SY='E';  M=  33, -58, -16,  55, -58, -50, -45, -54,  20, -55,  17,  19, -51, -13, -41,  26, -17, -13, -63,   3;
/M: SY='I';  M= -46, -60, -68, -62, -38, -71, -64,  66, -60,   0,  20, -62, -64,   9, -61, -35, -43,  64, -63,   5;
/M: SY='Y';  M= -58, -63, -66, -65,  63, -69, -39,  -3, -59,  31, -31, -64, -71, -57, -57, -58, -52, -20, -27,  97;
/M: SY='Q';  M= -24, -63,  13,  22, -62, -55, -41, -56,  23, -18,  10,  33, -55,  64,  41, -20,   1, -34, -66, -52;
/I:         I=-28; MI=0; MD=-71; IM=0; DM=-71;
/M: SY='L';  M= -36, -61, -25, -11, -45, -65,   5, -37,  47,  51, -32, -50, -61,   3,  35, -51, -22,  -7, -62, -46;
/M: SY='G';  M=   8, -63, -50, -17, -70,  93, -58, -74, -55, -71, -61, -39,  -7, -52, -62, -37, -53, -67, -62, -65;
/M: SY='I';  M= -31, -63, -66, -60,  10, -42, -58,  71, -13,  25,   5, -59, -63, -25,  19, -57, -48,   5, -56,   7;
/M: SY='Q';  M=  -6, -63,  29,  32, -64, -53,  42, -60,  19, -41,  25,  21, -53,  51,  12,  11,  -7, -58, -69, -50;
/M: SY='N';  M=   5,  23, -42,   6, -59, -52, -43, -53,  17, -26,  20,  56, -58,   8,  53, -10, -11, -11, -69, -53;
/M: SY='C';  M= -47,  50,  -8,   3, -65,  31,  14, -67,  45, -43, -54,  45, -57,  19,  29, -23, -46, -63, -68, -55;
/I:         I=-30; MD=-77;
/M: SY='A';  M=  81,   0, -14, -50, -66, -13, -60, -56, -23, -59, -53, -50, -58, -50, -56, -20,  -7, -27, -68, -62; D=-30;
/I:         I=-30; MI=-77; IM=-77; DM=-77;
/M: SY='R';  M= -48, -67, -38,  53,  -7, -59, -10, -62,  32, -58, -51, -42, -53,  54,  56,   9, -46, -30, -60,  -7;
/M: SY='P';  M= -51, -76, -53, -43, -72, -26, -55, -62, -13, -71, -58, -56, 117, -50, -13,  -4, -45, -66, -66, -68;
/M: SY='L';  M=  -4, -59, -55, -48,  -1, -59, -47,  -1,  17,  40,  12,  13, -61,  32,  -6, -13,  -6,  -4, -56,  19;
/M: SY='E';  M=  -6, -65,  46,  59, -66, -54, -42, -62,  23, -17, -53,   1, -51,  54, -17,   2, -44, -59, -68, -55;
/M: SY='R';  M= -51, -65, -18,  27, -11, -62,  23,  -3,   6,   6, -43, -14, -59, -35,  71,  -8, -18, -22,  28, -45;
/I:         I=-17; MD=-42;
/M: SY='L';  M= -55, -59, -72, -64,  -3, -75, -59,  10, -20,  77, -20, -70, -71, -59, -61, -65, -51,   4, -60, -42; D=-17;
/I:         I=-17; MI=0; MD=-42; IM=0; DM=-42;
/M: SY='Q';  M= -58, -77, -21,  41, -70, -25, -55, -30,  11, -15, -56, -54, -64,  59,   6, -55, -36, -12,  20, -60; D=-17;
/I:         I=-17; DM=-42;
/M: SY='R';  M=   5, -73,  20,   4, -37, -63, -52, -74,   6, -71, -63,  -2, -65,  43,  45,  -5, -26, -69, -76, -62; D=-17;
/I:         I=-17; DM=-42;
/M: SY='R';  M= -15, -70, -56, -45, -11, -63,  -4, -63,  14, -39,  -2, -49, -64,  50,  56,  14,   2, -37, -69, -54; D=-17;
/I:         I=-17; DM=-42;
/M: SY='H';  M= -14, -71, -52,  15, -14, -23,  81, -55, -50,  -7, -45, -51, -65,  27, -29, -52, -56, -29, -50,  73; D=-17;
/I:         I=-17; DM=-42;
/M: SY='R';  M= -17,   0, -11,  22, -64, -53, -11, -63,  43, -62, -53,  31, -53,  20,  43,  15,  33, -57, -68, -54;
/M: SY='Q';  M=   9, -64, -17,  33, -20,   9,  32, -26, -14, -35, -12,  -1, -55,  68,  14, -24, -48, -19,  20, -48;
/M: SY='F';  M=   0, -58, -67, -64,  97, -64, -51, -36, -58,   1,  22, -25, -68, -63, -22, -54, -12, -22, -35,  31;
/M: SY='Q';  M= -27, -15, -47,  21,  22, -13,  21, -32,  35,  14, -42, -45, -57,  68, -37, -21, -28, -52,  37, -41;
/M: SY='H';  M=  16,  40,  18,   3,  12, -15,  42, -28, -17, -10, -46, -13,  -5,   5,  34, -43,  -1, -33, -64, -19;
/M: SY='R';  M=  -9, -64, -48,   0, -22, -58,   4, -60,  32, -13, -48, -43, -58,  -4,  81,  10, -20, -56, -61, -10;
/M: SY='M';  M= -50,   9, -25, -16,   5, -67, -51,   7, -55,  45,  66, -59, -64,   1, -27, -31, -18,  24,   7,  16;
/M: SY='S';  M=  -3, -60, -44,  29, -56,  -5, -45, -31,   4, -25,  24, -42, -15,  20,  31,  46,  -2, -32, -62,   2;
/M: SY='R';  M=  -7, -63, -18,  19, -58, -30,  12,  -9,  32, -40,  -2, -41, -54,  36,  46,  19,   6, -52,  20, -10;
/M: SY='M';  M=  18, -61, -49,  -4, -14, -30,  26,  -8, -11,   4,  29,   8,  28,  28,  25,   7, -17, -46, -64, -48;
/M: SY='W';  M= -23, -62, -11, -26, -53, -13,  -3,   5,  15,  -1,  18,  29,  28,  16,  -4, -42,  36, -22,  50, -49;
/I:         I=-11; MD=-28;
/M: SY='S';  M= -16, -60,   2,   3,  -1, -56, -50, -11,   4,  16,  20, -23,  29,  12, -23,  31,   9,  -6, -64, -48; D=-11;
/I:         I=-11; MD=-28;
/M: SY='C';  M=  -8,  13,  -6, -78, -80, -24, -23, -22, -80,  -5, -15, -77, -29, -35, -33, -32, -75, -40, -97, -80; D=-11;
/I:         I=-11; MI=0; MD=-28; IM=0; DM=-28;
/M: SY='N';  M= -75, -84,   3,  23, -30, -75,  -1, -84, -61, -37, -76,  59, -80, -60, -36, -63, -20, -83, -98, -76; D=-11;
/I:         I=-11; DM=-28;
/M: SY='Q';  M=   1, -60, -22,  19,  12, -33,  14, -54,  -3, -53,  11,  37, -21,  61,  -3,  11,  11, -17, -64, -46;
/M: SY='N';  M= -47, -14,  42,   1, -59,  -1, -47, -47,   3, -11, -49,  43,  26, -18,   6,  -2,  -2,  20, -72, -56;
/M: SY='Q';  M=  29, -58,  -7, -17, -19,   2,  -3, -13, -46, -18,  19, -43, -55,  48, -49,  42,  -3, -12,  40, -47;
/M: SY='S';  M=   8,   5,  18, -26, -11,   8, -49, -20, -13,  -8,  -4,  12, -29,  15,  -5,  31,  -8,   6, -64,  -9;
/M: SY='E';  M=  -3, -61,  20,  38, -63, -38,  22, -27,  -8, -58, -52, -18,  36, -15,  16,  20,  37, -17, -71, -54;
/M: SY='D';  M= -19, -62,  52,  32, -62, -54, -45,  10,  -4, -35, -49,  26, -29,  49, -44,   8,  11, -10, -71, -54;
/M: SY='Q';  M= -30, -63,  -5,  19, -21, -21,  -2, -36,  -6, -39, -49,  -2,  42,  59, -15,  31,   3,  -9, -63, -10;
/M: SY='N';  M= -10, -59,  -5,  10, -57, -32,   3, -28,  -1,  -8,  14,  50,  10,  10,   4,  26,   6,  -6, -70, -52;
/M: SY='P';  M= -33, -67,  22,  27, -19, -57, -50, -50, -24,   3, -48,  12,  84,   2, -52, -26,  -8, -11, -67, -56;
/M: SY='Q';  M=  -3, -63, -41,  44, -21,  -8, -44, -55, -37, -20,  29,  -9,  22,  62,   3,  21,  -2, -54, -63, -52;
/M: SY='K';  M= -29, -61, -10,   5,  17, -36, -46, -45,  29,   8,  -3,  18,  -1,  22,  23, -19,  15,  -4, -59,  -7;
/M: SY='T';  M=   3, -59,  11,  14, -58, -54, -47,  -9,  -5,  -4, -46,  17,  -3,  18,  32,  14,  41, -47, -68, -53;
/M: SY='S';  M= -42, -60, -10,  -6, -26,  -1,  -7, -25, -17,  10, -46,   3,  36,  29, -26,  56,  -1, -51, -66, -51;
/I:         E1=0; IE=-255; DE=-255;
» more

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2024_01 which contains 570'830 sequence entries.


Total number of hits 11 in 11 different sequences
Number of true positive hits 11 in 11 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 0
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 100.00 %

Comments [info]

Matrix type [info] protein_domain
Scaling database [info] reversed
Author [info] CJA_Sigrist
Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 1
Feature key [info] DOMAIN
Feature description [info] BUB1 N-terminal
Version [info] 5

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
11 sequences

BUB1B_HUMAN (O60566), BUB1B_MOUSE (Q9Z1S0), BUB1_ARATH  (F4IVI0), 
BUB1_DICDI  (Q54CV5), BUB1_HUMAN  (O43683), BUB1_MOUSE  (O08901), 
BUB1_SCHPO  (O94751), BUB1_YEAST  (P41695), BUBR1_ARATH (O22806), 
MAD3_SCHPO  (O59767), MAD3_YEAST  (P47074)
» more

PDB
[Detailed view]
9 PDB

2LAH; 2WVI; 3ESL; 3SI5; 4A1G; 4AEZ; 5KHU; 5LCW; 6TLJ