PROSITE entry PS51507

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General information about the entry

PURL [info]	https://purl.expasy.org/prosite/signature/PS51507
Entry name [info]	IRF_2
Accession [info]	PS51507
Entry type [info]	MATRIX
Date [info]	01-AUG-2010 CREATED; 10-MAY-2017 DATA UPDATE; 29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info]	PDOC00522
Associated ProRule [info]	PRU00840

Name and characterization of the entry

Description [info]

IRF tryptophan pentad repeat DNA-binding domain profile.

Matrix / Profile [info]

/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=107;
/DISJOINT: DEFINITION=PROTECT; N1=6; N2=102;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=2.8007126; R2=0.0069866; TEXT='NScore';
/NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=18028.2734375; R2=1.6174334; PRIORITY=1; TEXT='Heuristic 0.5%';
/CUT_OFF: LEVEL=0; SCORE=816; H_SCORE=19348; N_SCORE=8.5; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=530; H_SCORE=18886; N_SCORE=6.5; MODE=1; TEXT='?';
/DEFAULT: M0=-49; D=-100; I=-100; B1=-1000; E1=-1000; MI=-255; MD=-255; IM=-255; DM=-255;

...

                A    C    D    E    F    G    H    I    K    L    M    N    P    Q    R    S    T    V    W    Y
/I:         B1=0; BI=-255; BD=-255;
/M: SY='K';  M= -97,-114, -15, -18, -13,  11,  40,-110,  65, -25, -99, -89,  25, -84,  52,  13, -95,-108,-108,   7;
/M: SY='M';  M= -28,-110, -97,  16,-102,-106, -95, -91, -34,  16,  70,  -3,  41,  45,  26,  11,  16, -13,-114, -99;
/M: SY='W';  M= -20,-115,  10, -93,-100, -24,  47,-102, -31,  -1,  17,  -8, -20,   4,  72, -20, -99, -23,  98, -90;
/M: SY='M';  M= -22,-106,-120,-113,  36,-118,-104,  35,-111,  67,  84,-114,-115,-106,-110,-109, -97, -22,-104, -84;
/M: SY='R';  M= -31,-111, -98, -89,-108, -44, -96, -11,  42, -45, -96, -90,  -3,   5,  79,  11,  43, -36,-113,-100;
/M: SY='P';  M=  11,-114,  63,  42,-115,-102,   1,-110, -34, -31,-104,  -9,  74, -19, -11, -15, -23,-108,-120,-107;
/M: SY='W';  M=-112,-128,-135,-117,  71,-112,-127,-102,-110, -97,-103,-127,-117,-112,-112,-116,-118,-113, 171, -61;
/M: SY='L';  M=-102,-107,-120,-114, -10,-123,-109,  62,-113,  80, -68,-115,-116,-108,-113,-110, -10, -69,-107, -89;
/M: SY='I';  M= -98,-108,-108,  16, -17,-119,-107,  58,   6,  38, -77,-107,-110,-100, -31,-103,  -5,  47,-109,  -9;
/M: SY='E';  M=   5,  17,  44,  63,  -1, -15, -93,-111,   0,-108,  -9, -22,  22,  33, -92,   2, -94,-107,-111,   6;
/M: SY='Q';  M=  42,  47, -96, -85,-113,-101,  58, -19,  36,-105, -96,  -3,-105,  80,  35, -88, -95,-102,-114, -98;
/M: SY='L';  M= -20,  22,-120,-114, -83,-120,-112,  57,-113,  66, -71,-115,-116,-109,-113,-107, -95,  43,-112, -93;
/M: SY='D';  M= -97,-113,  77,  76,-119,  -6, -88,-119, -85,-117,-111,  58, -99,  -9, -93,  -6, -92,-115,-125,-108;
/M: SY='S';  M=  -3,-105, -86,  34,-111, -92,  18,-111, -86,-112,-104,  50,-101,  -2,   9,  83, -15,-105,  21,-101;
/M: SY='G';  M= -93,-112,  25,  13,-118,  69, -94,-120,  23,-119,-109,  65,  17, -90, -19, -30, -95,-116,-117,-110;
/M: SY='T';  M=   6,-108,   9,   0,-106,-103, -10, -24,  42,   0, -94,  15,-103,  24,  34, -13,  51, -97,-116,-100;
/M: SY='Y';  M=-105,-114,-111,-112,  58,-117,  20,  27,-106, -83, -83,-108,-118,-104,-104,-104, -99,  16, -75, 116;
/I:         I=-30; MI=0; MD=-77; IM=0; DM=-77;
/M: SY='P';  M= -98,-120,   8,  13,-114,-103,   1,-110, -92, -47,-104, -98, 107, -10,   0,  25, -30,-111,  47,-107;
/I:         I=-30; MI=0; MD=-77; IM=0; DM=-77;
/M: SY='G';  M= -89,-112,  -8,-106,-108,  93,  17,-113,-101, -26,-103, -27,-106, -99, -12, -21,-101, -29,-109,   9;
/M: SY='L';  M=-100,-105,-121,-113,  18,-121,-107, -11,-113,  79,  21,-117,-118,-109,-111,-110, -96,  45,-107, -87;
/M: SY='H';  M= -25,  47, -92,  39,  -1,  -5,  67, -12,  14,-101, -96, -90,-104,  38, -11,  27, -10,   1,-115, -95;
/M: SY='W';  M=-111,-135,-135,-116, -74,-110,-126,-108,-108,-105,-107,-129,-116,-107,-110,-117,-121,-121, 179,  47;
/M: SY='C';  M= -20,  50,  12,  24,  -1,-114,-105,  23, -31,  30,  26,-104,-110,   2,-104,-101, -94,  50,-114, -95;
/M: SY='D';  M=-100,-113, 109, -21,-121, -23, -87,-120, -89,-120,-115,  69,-104, -89, -98, -22, -90,-117,-135,-107;
/I:         I=-30; MI=0; MD=-77; IM=0; DM=-77;
/M: SY='E';  M= -97,-116, -82,  80,-116, -25, -92,-117,  38,-113,-104, -91,  15,   4,  64, -28, -18,-111,-114,-105;
/M: SY='D';  M= -25,-112,  62,  60,-119, -24, -89,-116,  -3,-115,-107,  49, -22,  50, -90,  24, -90,-112,-121,-106;
/M: SY='K';  M= -98,   5, -87,  22,-112,-104, -91,-111,  83, -41,-100,  50,-102, -15,  41, -90,  18,-107,-114,-103;
/I:         I=-28; MD=-71;
/M: SY='T';  M= -30,-108,  -9, -96,-107,  37,-100,-103,  30, -11,  28, -89,-104, -93,  44, -87,  71, -99,-116,-103; D=-28;
/I:         I=-28; MI=-71; MD=-71; IM=-71; DM=-71;
/M: SY='I';  M= -96,-109,-110,-105,  -6,-115,-108,  59, -32,  -3,  -5,-101,-109, -12,  29,  10,  42,  37,-114, -95; D=-28;
/I:         I=-28; DM=-71;
/M: SY='F';  M=-108,-107,-124,-119, 121,-120,-106, -20,-115, -21, -84,-113,-121,-123,-112,-110,-101,  12, -81, -60;
/M: SY='R';  M=   3,-111, -97, -87,-109,-104,  13,-104,  47, -25, -96, -90,-106,  36,  79,  22,  -8, -17,-113, -98;
/M: SY='I';  M=   7,-108,-119,-114, -87,-118,-116,  83,-112,  24,   6,-112,-112,-109,-114,-104, -93,  52,-113, -94;
/M: SY='P';  M= -20,  13,-102, -93,-117,  -7,-104,-108, -16, -40,-103,-102, 116, -17,-105,  10, -93,-110,-115,-114;
/M: SY='W';  M=  23,-126,-129,-113, -82, -22,-131,-105,-107,-105,-106,-122,-113,-106,-111,-108,-114, -27, 173, -70;
/I:         I=-5; MD=-14;
/M: SY='K';  M=-101,-113, -98, -95,-106,-110,  18, -33,  63,-104,  12,  36,   1, -91,  19, -94,  45,  14,-117,   5; D=-5;
/I:         I=-5; MD=-14;
/M: SY='H';  M=-107,-120, -95, -92,-111,-110, 125,-118,  20, -30, -97,  24,  27, -12,  24, -98,-103,-118,-130, -88; D=-5;
/I:         I=-5; MD=-14;
/M: SY='A';  M=  46,  13,-104, -98, -35,  24,-104,-105,  28,  -9,-100,  10,  30,  21,  -9, -92, -98, -32,-116,-108; D=-5;
/I:         I=-5; MD=-14;
/M: SY='A';  M=  48,-107,-101, -99,-112,  16,-102,-106,  17, -24,  16,  19,-107, -95,  -9,  41,  18,-101,-118,-107; D=-5;
/I:         I=-5; MD=-14;
/M: SY='R';  M=  13,-115,  13, -12,  18,   5, -97,-115,  21,-111,-105,  -2,-109,  22,  57,  16, -97,-110,-111, -12; D=-5;
/I:         I=-5; MD=-14;
/M: SY='H';  M=   8,-122,   2, -91,-118,-108,  58,-120,  38,-118,-107, -96,  48,  52,  -8,   9,-101,-117,-120,   0; D=-5;
/I:         I=-5; MD=-14;
/M: SY='D';  M= -33,  17,  60, -95,-122,  30,   1, -48, -98,-118,  19,  55,-114,   3,   7, -17,-101,-117,-131,-112; D=-5;
/I:         I=-5; MD=-14;
/M: SY='W';  M=-110,  13,-122,-117,  13, -26,-107, -14,-111,-103,-102,-117,  13,-111, -30,  -4,-109, -10, 119,  79; D=-5;
/I:         I=-5; MD=-14;
/M: SY='D';  M= -40,   2,  63, -18,-126,-113,-107,-114, -43,-121,-117,  45,   1,  -7,-111, -24,   6,   8,-141,-119; D=-5;
/I:         I=-5; MI=0; MD=-14; IM=0; DM=-14;
/M: SY='E';  M=-107,-124,  57,  57,-124,-113,-101,-123, -16,-121,  -2,  15,   1,  10, -14,  -9, -18,-121,  34,-112; D=-5;
/I:         I=-5; DM=-14;
/M: SY='D';  M= -42,  21,  47,  19,-122,   5,-102,-118,  36,-119,-112, -12,-111, -16,  37, -37, -21, -21,-126,-113; D=-5;
/I:         I=-5; DM=-14;
/M: SY='D';  M=-107,-122,  90,   2,  -5,   0,  64,-120,-100,-114,   9, -86,-110, -96,-105, -26,-103,-119,  49,  -1; D=-5;
/I:         I=-5; DM=-14;
/M: SY='C';  M=   2,  66,  -7, -25, -13,  46,   4,-109,-104,-111,-106,   8,-114,-104, -12,  -5, -11,   1,-118,   9; D=-5;
/I:         I=-5; DM=-14;
/M: SY='C';  M=  16,  40,  -6,  29,-113, -25,-101,-104,  37, -47,  19,  -2,  -2,  10, -16,   2, -37,  -1,-120,-108; D=-5;
/I:         I=-5; DM=-14;
/M: SY='I';  M= -26,-112,-122,-117,  18,-122,  24,  69,-114,  19,  61,-114,-116,-111,-115,-110, -99,  35,-113, -91; D=-5;
/I:         I=-5; DM=-14;
/M: SY='F';  M=-111,-115,-120,-117, 104, -29, -97, -91,-112, -86, -91,-113,-123,   1,-110,-109,-106, -21, -80,  80; D=-5;
/I:         I=-5; DM=-14;
/M: SY='K';  M=-102,-116,  32,  20,-110,-114,  23, -98,  66,  -7, -11, -95,  -4, -89,  16,-101, -98,  28,-120,-103; D=-5;
/I:         I=-5; DM=-14;
/M: SY='A';  M=  64,-110,  49,  27,-116,  -8,-103,-105, -96, -53,-104, -95,-107,   5, -11, -37, -96,   2,-121,-110; D=-5;
/I:         I=-5; DM=-14;
/M: SY='W';  M=-114,-130,-131,-119,  39,-116,-114,-102,-112,-100,-103,-127,-121,-112,-113,-117,-117, -25, 159,  72; D=-5;
/I:         I=-5; DM=-14;
/M: SY='C';  M=  82,  87,  20, -99,-109, -96,-107, -21,-103, -30,  18, -99,-109,-101,-108, -87, -93, -91,-119,-108; D=-5;
/I:         I=-5; DM=-14;
/M: SY='K';  M= -99,-114, -97,  39,-102,-114, -99,   2,  42, -16,  20, -13,-108,   5,  36, -24, -96,  36,-113,   5; D=-5;
/I:         I=-5; DM=-14;
/M: SY='H';  M=   4,  20, -94,  46,  11,-110,  84, -97, -16,  15,  37,  24,-109, -92, -98, -98, -99,  -9,-118, -92; D=-5;
/I:         I=-5; DM=-14;
/M: SY='R';  M= -97,  25,   1, -92,-111,-107, -98,-110,  33, -35,-102, -90,-107, -88,  74,  35,  55,-105,-120,-104; D=-5;
/I:         I=-5; DM=-14;
/M: SY='G';  M= -96,-118,  20, -20,-120,  78,  25,-120, -16,-120,-111,  17,-110, -99,  17, -93,-104, -15,-121,-111; D=-5;
/I:         I=-5; DM=-14;
/M: SY='R';  M=-105,-119,-105, -97,-112,-116,-104,  39,  62,-105,-100,  -6,-112, -91,  66,  -8, -17, -28,-119,-106; D=-5;
/I:         I=-5; DM=-14;
/M: SY='Y';  M=-113,  40, -11,-111,  16,-121,  38, -25,-109, -10,  14,-112,  47,-109, -12,-111, -29,-106,  64,  65; D=-5;
/I:         I=-5; DM=-14;
/M: SY='Q';  M=-106,-119,  27, -34, -24,-114,  30,-100,  19,  24, -96,   9,  -7,  57, -97, -26, -31,  -3,-122,-103; D=-5;
/I:         I=-5; DM=-14;
/M: SY='Q';  M= -11,-120,  21,  32,-121, -14,   1,-112,   6, -51,-107, -97,  40,  44,-100, -95,  35, -27,-125,-112; D=-5;
/I:         I=-5; DM=-14;
/M: SY='G';  M= -95,  20, -12, -25, -14,  57,-103,-110,-104,-113,-108,   7,  -9,   3,-109,  42, -97,  -3,-113,  29; D=-5;
/I:         I=-5; MI=0; MD=-14; IM=0; DM=-14;
/M: SY='D';  M=-121,-134,  55,-107,-119,  -2,-113,-121, -42,  15,-114,  -4,-130, -20,  15,-116,-118,-123,-132,   9; D=-5;
/I:         I=-5; DM=-14;
/M: SY='Q';  M= -48,-127,  -9,   0,-120, -22,  28,-118,  16, -34,-109, -18,  34,  37,  29,-105, -32, -38,-124, -13; D=-5;
/I:         I=-5; DM=-14;
/M: SY='P';  M= -12,-118, -15,  16, -25,  -4,  46,-108, -99, -34,-103, -99,  89, -13,-106,  26, -95, -29,-119,-106; D=-5;
/I:         I=-5; DM=-14;
/M: SY='D';  M= -98,-112,  65,  24,-108, -99,  12,-116, -85,-115,-108,  65,-106, -86,  37,  43, -90,-113,-118,  29; D=-5;
/I:         I=-5; MI=0; MD=-14; IM=0; DM=-14;
/M: SY='P';  M=-101,   3,-112,-103,   6,  -5,-105, -14, -24,  15,  11,-109,  82,  -5,-107,-103, -99,  21,  45,  31; D=-5;
/I:         I=-5; DM=-14;
/M: SY='S';  M=  17,  28,-100, -95,-106, -15,-100, -95,  28, -32,  17, -11,  26, -92,  24,  38,  28,  18,-116,-103;
/M: SY='E';  M= -43,-110,  20,  42,  12,-107, -95, -96,  32, -99,  18, -90,-103,  29,  33,  13,  24,  23,-113, -96;
/M: SY='W';  M=  16,  67,-115,-105, -92,   3,-115,-105,   8, -18,   4,-108,   6,-101, -21,-100, -10,-106, 144, -84;
/M: SY='K';  M= -98,-114, -92, -10,-113,-107, -94, -10, 102,-110,-100, -86,-101,  10,  36, -15, -94,-105,-109,-101;
/M: SY='T';  M=  18,-105, -97, -94,-106,  -1, -99,  19, -15, -98,   7,  -1,-102,  28,  36,   2,  75, -90,-116,-101;
/M: SY='N';  M= -17,-110, -86, -93,-109, -21, -87,-109, -75,-112,-102,  97,-110, -84,  82, -88, -92, -20,  46,-101;
/M: SY='F';  M=-107,-108,-121,-115, 103,-119,-101, -20,-109,  43,  41,-113,-119,-112, -10,-110,-101, -84, -86,  14;
/M: SY='R';  M= -25,-114,-104, -96,-102,  35, -95,-102, -75,  35, -90, -96,-112, -86,  98, -97,-101,-101,-110, -99;
/M: SY='C';  M=  13, 113,-100,-100,-104, -18, -98,-111,  -7,-108,-102,  33,-112, -96,  34,  31, -22,-103,-115,  24;
/M: SY='A';  M=  87,-101, -19,-100,  24,   5,-107,   9,-102, -36, -93, -99,-106,-100,-106, -84, -91, -20,-108, -98;
/M: SY='L';  M= -24,  31,-118,-113, -10,   5,-108,  45,-112,  65,  45,-111,-115,-107,-112,-105, -97,   7,-109, -92;
/M: SY='R';  M= -26,-110, -88, -91,-111, -24, -88,-109, -17,-111,-101,  82,-109, -83,  89, -21,  -1, -22,-119,-103;
/M: SY='K';  M= -38,-110, -91,  13,-108,-102,  43,-107,  56,  -5, -97,  -8,-103, -20,  55,  48,  -1,-104,-115, -98;
/M: SY='S';  M= -92,   8, -98, -99, -95,-102,  56, -88,  -6,  45, -86,  34,-108, -93, -98,  59,  23,   6,-118, -95;
/M: SY='R';  M=  11,-114,   3, -88,-109, -38,  34,-112,  20,-110,-100,  -9,  55,   5,  75, -91,   7,-108,-112,   7;
/M: SY='D';  M= -97,-112,  65,  14,  31,  43, -93,-109,   8,-105,  -5, -86,-105, -92,  -1, -25,  17,-107,-103,  47;
/M: SY='F';  M=  -7,-107,-115,-110,  73, -26,   4,  39, -32,  11,  21,-106,-113,-107, -19,-101,  -7,  36,-100, -80;
/M: SY='E';  M= -45,-114, -26,  62, -14,-108, -92,  -3,   7, -54,  51,  28,-103,  45,  45, -95, -96, -37,  45, -96;
/M: SY='E';  M= -98,  45,  14,  76,-109,-110, -92, -33, -17, -32,-100,   0,-102,  20,  55, -93, -11, -39,-115, -15;
/M: SY='L';  M=   3,   7,  21,-101, -89,-112,-104,  22,-105,  58,  34,-105,-113,  21,-106, -32, -94,  34,-114, -95;
/M: SY='P';  M= -94,-111,  34,   4,-106, -27,   5,-104,  39,-108,-101, -88,  44, -87,  22,  42,  18,  -2,-112,  22;
/M: SY='D';  M= -25,-112,  57,   9, -17,   1,  36,-106,  19,-106,  10, -86,  19,  38,  10, -14,  16, -19,-117, -99;
/M: SY='R';  M= -97,  21, -14,  48,  -1,   9,  -4,   1,  30,-104, -99, -91, -10,   9,  57, -28, -11, -35,-112, -99;
/M: SY='N';  M=   0,-108,  13,  18,-112, -96,   6, -22, -15,-108,-101,  60,  30,  24,  -8,  48, -11, -22,-120,-103;
/I:         I=-16; MD=-40;
/M: SY='Q';  M= -25,   3,  29, -25,-104,-102, -93,-102,  22, -39, -99,  41,-107,  46,  -7,  31,  19,  -3,-114,  28; D=-16;
/I:         I=-16; MD=-40;
/M: SY='Q';  M=  -8,  -2,  -2,  28,-109, -39, -99, -31,  16,  13, -96,  15, -25,  45,  -9, -31,  38,-100,-119,-105; D=-16;
/I:         I=-16; MD=-40;
/M: SY='Q';  M= -15,-112,  30,   6,  -7,  19, -98,-105,   1,-108,-103,  11,-107,  43,  -6,   3,  25,   5,-115,  -5; D=-16;
/I:         I=-16; MD=-40;
/M: SY='G';  M=   1,-114,  14,-101,  -1,  44,  19, -17, -32, -45,-101,  20,-112,   7, -10, -23, -16,   2,-114,  10; D=-16;
/I:         I=-16; MD=-40;
/M: SY='Q';  M= -97,-118,  35, -14,-121,  33,  15,-115, -97,-118,-110,   3,  38,  42, -21,  40, -97, -14,-124,-110; D=-16;
/I:         I=-16; MD=-40;
/M: SY='D';  M= -27,-123,  34,  15,  -2,  22,  -5,-118,   6, -36,-113, -23, -14, -26, -38,  -6, -29, -37,-126,-111; D=-16;
/I:         I=-16; MI=0; MD=-40; IM=0; DM=-40;
/M: SY='P';  M=  29,-111, -92, -23,-115,  15,  15,-111, -89,-114,-103,  59,  80, -92,  27, -11,  -4,-108,-118,-108;
/M: SY='Y';  M= -21,  71,-104, -17,  59,-111,  60, -95,-100, -92, -91,  -1,-115,-100, -16, -98, -24,  -6, -87,  93;
/M: SY='R';  M=-100,-113, -97, -88,-105,-110, -93,-102,  67,   8, -93,   0,-108, -81,  89, -95,  -9, -19,-112, -99;
/M: SY='V';  M= -95,-107,-118,-111,  -5,-121,-115,  57,-106,  16, -76,-112,-114, -11,  -3,-105, -92,  81,-114, -93;
/M: SY='Y';  M=-108,-116,-111,-108,  71,-115, -87, -16,  12, -88, -89,-108,-117,-101, -11,-105,-103, -96,  83, 111;
/M: SY='R';  M= -45,-118, -94,   2,-111,-108, -89,-115,  50,-110, -99, -90,  -2,  73,  87, -93, -98,-111,-107,   5;
/M: SY='F';  M=-102,-107,-117,-114,  65, -24,-106,  43,-112,  62,  20,  -2,-117,-110,-111,-108, -98,  -4,-100, -81;
/M: SY='R';  M= -44,  -9,-105, -97, -95,-112,-101,  -5,  40,  36,  19, -16, -19, -13,  43, -36, -11,  39,-113, -97;
/M: SY='P';  M= -96,  31,  55, -87,-112,  -7, -98,-110,  21,-111,  19,  -8,  73, -93,  -6,  29,   7,-109,  45,-105;
/I:         E1=0; IE=-255; DE=-255;

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Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_02 which contains 573'230 sequence entries.

Total number of hits	34 in 34 different sequences
Number of true positive hits	34 in 34 different sequences
Number of 'unknown' hits	0
Number of false positive hits	0
Number of false negative sequences	0
Number of 'partial' sequences	0

Precision (true positives / (true positives + false positives))	100.00 %
Recall (true positives / (true positives + false negatives))	100.00 %

Comments [info]

Taxonomic range [info]	Eukaryotes
Maximum number of repetitions [info]	1
Matrix type [info]	protein_domain
Scaling database [info]	reversed
Author [info]	CJA_Sigrist
Feature key [info]	DNA_BIND
Feature description [info]	IRF tryptophan pentad repeat
Version [info]	4

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences

34 sequences

IRF1_BOVIN  (Q3SZP0), IRF1_CHICK  (Q90876), IRF1_HUMAN  (P10914),

IRF1_MOUSE  (P15314), IRF1_PIG(A0FIN4), IRF1_RAT(P23570), 
IRF2_CHICK  (Q98925), IRF2_HUMAN  (P14316), IRF2_MOUSE  (P23906), 
IRF2_SIGHI  (Q8R4E0), IRF3_BOVIN  (Q4JF28), IRF3_CHICK  (Q90643), 
IRF3_HUMAN  (Q14653), IRF3_MOUSE  (P70671), IRF3_PIG(Q764M6), 
IRF4_HUMAN  (Q15306), IRF4_MOUSE  (Q64287), IRF5_BOVIN  (Q58DJ0), 
IRF5_HUMAN  (Q13568), IRF5_MOUSE  (P56477), IRF6_BOVIN  (Q08DD6), 
IRF6_HUMAN  (O14896), IRF6_MOUSE  (P97431), IRF7_HUMAN  (Q92985), 
IRF7_MOUSE  (P70434), IRF8_CHICK  (Q90871), IRF8_HUMAN  (Q02556), 
IRF8_MOUSE  (P23611), IRF9_HUMAN  (Q00978), IRF9_MOUSE  (Q61179), 
VIRF1_HHV8P (F5HF68), VIRF2_HHV8P (Q2HR71), VIRF3_HHV8P (F5HIC6), 
VIRF4_HHV8P (Q2HR73)

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Retrieve an alignment of UniProtKB/Swiss-Prot true positive hits:
[Clustal format, color, condensed view] [Clustal format, color]
[Clustal format, plain text] [Fasta format]
Retrieve the sequence logo from the alignment

PDB
[Detailed view]

19 PDB

1IF1; 1IRF; 1IRG; 1T2K; 2DLL; 2IRF; 2O61; 2O6G; 2PI0; 3QU3; 3QU6; 4HLY;
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