Entry: PS51542

Forthcoming changes to the profile format
General information about the entry

Entry name [info] FYRN
Accession [info] PS51542
Entry type [info] MATRIX
Date [info] JUL-2011 (CREATED); OCT-2013 (DATA UPDATE); OCT-2014 (INFO UPDATE).
PROSITE Doc. [info] PDOC51542
Associated ProRule [info] PRU00875

Name and characterization of the entry

Description [info] FYR domain FYRN motif profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=60;
/DISJOINT: DEFINITION=PROTECT; N1=6; N2=55;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=2.2239439; R2=0.0097524; TEXT='NScore';
/NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=6266.32694; R2=14.06172; TEXT='HScore';
/CUT_OFF: LEVEL=0; SCORE=952; N_SCORE=11.5; H_SCORE=18205; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=439; N_SCORE=6.5; H_SCORE=12425; MODE=1; TEXT='?';
/DEFAULT: M0=-28; D=-150; I=-150; B1=-1000; E1=-1000; MI=-380; MD=-380; IM=-380; DM=-380;
...
                A    C    D    E    F    G    H    I    K    L    M    N    P    Q    R    S    T    V    W    Y
/I:         B1=0; BI=-380; BD=-380;
/M: SY='M'; M= -27, -12, -13, -16,  10, -14,  -7,  -6,   5,  16,  25,   2,  15, -17, -11, -15,   0,   2, -48, -42;
/M: SY='P'; M= -40, -26, -35, -36,  37, -70,  13, -10, -35,  12,  -1, -28,  66, -39, -42, -19, -27,  14, -90,   5;
/M: SY='P'; M= -17,  -2, -35, -30,   3, -39,  13,   3, -11,   6,  -4, -18,  66,   8,  -7, -42, -17, -19, -94,  -8;
/M: SY='F'; M= -19, -93, -37, -21,  30, -37, -19,  23,   5,  21,  28, -11, -44, -42,  11, -38, -16,   5, -89,  -1;
/M: SY='R'; M= -10, -94, -39,  -8,  -8, -39, -11, -14,  -5,  16,  33, -13,   1,   4,  41, -38,   2,   5, -35, -54;
/M: SY='I'; M= -17, -21, -16, -86, -17,  -3, -40,  34, -28,  -1,  -6,   3, -56, -38, -20,  32,  -1,  27, -97, -30;
/M: SY='G'; M= -28,   3,  -8,   1, -57,  64,  20, -32, -22, -37, -85, -14,  13, -20, -38, -13,   3, -52, -97, -14;
/M: SY='S'; M= -11,  -8,  24, -53, -70,  26, -15, -59,  -8, -66,  42,  30, -16, -11, -26,  55,   6, -59,-100, -55;
/M: SY='L'; M= -35, -42, -98, -92,   6, -53, -89,   0, -73,  61,  30, -66, -97, -36, -68, -35,  -6,  47, -92, -45;
/M: SY='T'; M= -39, -54, -23,  42, -24, -89, -29,   2,  -9, -25,  32,  -6, -84,  17,  18,  -9,  58, -11, -54, -47;
/M: SY='V'; M= -52, -90,-100, -63,  23,-102, -96,  60, -93,  29, -58, -96,  22, -71, -74, -68, -75,  60, -92, -73;
/M: SY='H'; M= -67, -92,   1,  17, -58, -95,  63,  20, -32,  26, -23, -14, -90, -37,  -9, -51,  14,  20, -11,  36;
/M: SY='S'; M=  -2,  31,  14,   9, -94, -75, -15, -93,   2, -70, -86,  57, -85,  -3,   3,  68, -34, -70,-103, -86;
/M: SY='L'; M= -58, -89,-100, -95,  23,-101, -39,  36, -94,  71,  17, -53, -56, -89, -93, -41, -32,   0, -86, -13;
/M: SY='G'; M= -68, -95, -83, -94, -53, 104, -89,-106, -88, -78, -92, -39, -49, -86, -95, -68, -86, -82, -39, -94;
/M: SY='Q'; M=  -6, -15, -55,  31, -37, -49,  17, -41,  36, -86, -23, -51, -84,  49,  28,  19,  31, -18, -96, -48;
/M: SY='I'; M= -80, -90,-102, -66, -17,-105, -96,  71, -94,  43, -33, -97, -97, -92, -61, -90, -76,  55, -11, -32;
/M: SY='V'; M= -35, -40,  18, -26, -34, -93,  29,  27, -52,   9,   9, -21,  -6, -27, -42, -10,   6,  53, -98, -17;
/I:         I=-17; MD=-42;
/M: SY='P'; M= -26, -99, -22, -32, -16, -33,  -3, -37, -13, -46, -36, -25,  66,  -2, -12,  10,  24, -19,  49,  11; D=-17;
/I:         I=-17; MD=-42;
/M: SY='D'; M= -11,-101,  55,  -2, -63,  27,  29,-103,  -7, -67, -93,   2, -37, -18,  27, -30, -27, -59,-108, -91; D=-17;
/I:         I=-17; MD=-42;
/M: SY='R'; M= -55,-117, -57, -93,-114, -86, -59, -89, -62, -48, -54,   7,  -4,  37,  39,  27, -69,-111, -41, -48; D=-17;
/I:         I=-17; MI=0; MD=-42; IM=0; DM=-42;
/M: SY='P'; M=  -8, -33,  20,  24, -38,  -7, -50, -63,  36, -66, -21, -20,  60,   8,   4,  10, -20, -59, -96, -45; D=-17;
/I:         I=-17; DM=-42;
/M: SY='N'; M=  19, -28, -15, -49,   1,  26,  29, -83,  -6,  -1, -12,  35,  -6, -58,   4,  19,   2, -45, -35, -24;
/M: SY='F'; M= -65, -93, -95, -91,  92, -41, -80, -75, -59, -46,  -1, -25, -36, -38, -11,  20, -81, -60,  92,  55;
/M: SY='H'; M= -53,  68,  23, -74, -13,  -1, 117, -93, -22, -72, -78, -34, -90,  -9, -77, -16, -29, -33, -51,  13;
/M: SY='N'; M= -50,  31,  31, -51, -60, -30,  19, -66,  -4, -43, -83,  58, -19, -31, -51,  48,  49, -56,-104, -53;
/M: SY='E'; M=   1, -94,  36,  44, -34, -35, -11, -57,  40, -74, -68, -32,  17,  17,  -3,  23, -40, -32, -95, -21;
/M: SY='R'; M= -21, -37,  17, -13, -39, -16,  41, -55,  21, -73, -63,  13, -27,  34,  46,   7,  23, -38, -24,  -3;
/M: SY='Y'; M=  41,  -3, -63, -34,  11, -85,  56, -48,  -6, -47,  -3, -23, -91, -15, -24, -30, -18, -18,  11,  81;
/M: SY='I'; M= -36, -26, -98, -61, -70,-101, -96,  87, -93,  22,  -5, -63,  28, -90, -96, -49, -43,  15, -93, -53;
/M: SY='Y'; M= -71,   0, -97, -95,  74, -70, -73, -20, -89, -29, -70, -48,-101, -89, -88, -88, -51, -35,  94, 102;
/M: SY='P'; M= -84,  -6, -85, -75, -50, -87, -88, -89, -81, -50, -86, -60, 126, -84, -54, -53, -55, -68, -97, -98;
/M: SY='V'; M=  -4, -40,  13,   4, -79, -68, -91,  39,  10, -19, -67, -61,  12, -48, -83, -66, -21,  66,-100, -82;
/M: SY='G'; M= -69, -95,   1, -88,-100, 100, -86, -63, -70,-103, -93,   4, -45, -52, -92, -68, -84,-100, -94, -95;
/M: SY='Y'; M= -91, -95, -95, -95,  85, -98, -65, -70, -88, -50, -44, -92,-102, -88, -85, -87, -84, -52, -51, 116;
/M: SY='R'; M= -66,  26, -44,  12, -89, -89,   8, -56,  47, -51, -15, -38, -85,  22,  53, -15,  48,  -3, -45, -53;
/M: SY='C'; M=  50,  76, -48, -81, -86, -64, -86, -11, -81, -81, -21, -74, -87, -78, -86,  65,  14,  11,-100, -50;
/M: SY='S'; M= -50,  -5, -58,  27, -43, -57, -39, -14, -11, -34, -18, -58, -84, -10,  47,  50,  49,  -3, -43, -50;
/M: SY='R'; M= -56, -46, -84, -73, -86, -94, -27, -81,  12, -69, -78, -64, -92, -32, 101, -79, -20,  26,  67, -76;
/M: SY='I'; M=  -8, -90, -62, -27, -30, -56,  19,  32,  28,  27, -12, -46, -57,   3,   6, -27,  16,  13,  16, -25;
/I:         I=-16; MD=-40;
/M: SY='Y'; M= -77, -27, -98, -71,  69, -85,  -1, -75, -92, -38, -29, -94, -32, -91, -63, -34, -60, -14, -27, 102; D=-16;
/I:         I=-16; MD=-40;
/M: SY='W'; M=  -4,-102, -99, -43,  37, -50, -15, -35, -20, -31,   0, -46,   5, -61,  -4, -45, -17, -36, 121,  28; D=-16;
/I:         I=-16; MD=-40;
/M: SY='S'; M= -50, -35, -20, -80, -27, -66,  21, -53, -50, -97, -91,   9, -90, -46, -25,  91, -65, -37, -11, -85; D=-16;
/I:         I=-16; MD=-40;
/M: SY='M'; M= -38,   8, -60, -91, -18, -29, -33,  -8, -52,  -2,  43, -87,  29, -89, -28,   4,  41,  23, -23, -37; D=-16;
/I:         I=-16; MD=-40;
/M: SY='K'; M= -25, -20, -10, -50,  -2, -47, -16, -29,  34,   3, -80, -55, -97, -12,  29, -14,   9,  10,-102, -85; D=-16;
/I:         I=-16; MI=0; MD=-40; IM=0; DM=-40;
/M: SY='D'; M= -21,  -4,  81,   0,-101, -46,  25,-102, -23, -92, -95,  46, -49, -60,  -5,   0, -27, -92,-112, -29; D=-16;
/I:         I=-16; DM=-40;
/M: SY='P'; M=   8,-101, -23, -47, -49, -14, -31, -24, -13,  -9, -60,  -9,  95,  -7, -53, -48, -29, -63, -99, -92; D=-16;
/I:         I=-16; DM=-40;
/M: SY='W'; M= -45, -93,  41,  -5, -27,   9,  27, -36,   8, -41, -42,  39, -22, -37,  36,  -8,  17, -45,  43, -20;
/M: SY='K'; M= -31, -24,  -9,  16, -26, -12, -24, -79,  45, -50, -81,  17, -15,  38,  42,  11,  11, -29, -95, -82;
/M: SY='R'; M= -43, -41, -32, -24, -60,  14, -20,  -4,  31,  -6,  12, -61, -25, -28,  67,  -1,   3, -35, -33, -21;
/M: SY='C'; M=   5, 102, -89, -25, -14, -75, -91,   7, -85, -61,   3, -41, -93, -19, -64,   6,  22,  47, -51, -83;
/M: SY='W'; M= -60, -16, -71,  -3,  -6, -92, -17,  -4,   4,  12,  -2,   0, -25, -28,  34, -14,  23,  14,  75,  18;
/M: SY='Y'; M= -71, -11, -91, -92,  33, -62,  13, -44, -60, -59,  -8, -89,-100, -81, -82, -62, -83, -26,  55, 123;
/M: SY='T'; M= -44, -90, -22,  13, -64, -92,   8,  36,  27, -23, -17, -33, -85, -13,  22, -48,  58,  11, -96, -17;
/M: SY='C'; M=  -9, 119, -89, -88, -15, -84, -86, -19, -85, -37,  65, -16, -95, -31, -89,  50, -71, -45,-102, -84;
/M: SY='E'; M= -53, -94, -38,  75, -94, -87,  -9, -56,  25, -67, -18, -50,  -8,   9,  35,  28,   9, -66, -96, -45;
/M: SY='I'; M= -77, -91, -99, -96, -41, -61,-101,  90, -63, -55, -58, -90, -92, -91, -52, -44,   8,  57, -96, -76;
/M: SY='L'; M= -30,  -7, -14,  24, -35, -46,   8,  -6,   7,  40, -27, -28, -89, -34,  -8,   4,  19,  10, -94, -21;
/M: SY='D'; M= -39,  -6,  76,  59, -95, -37, -47,  -9, -27, -49, -85,  -4, -45,  -8,  10, -34, -25, -15,-104, -86;
/M: SY='G'; M=  14,  34,  15, -15, -50,  45, -35, -71, -15, -78, -83,  31, -59,  18,  -8,   2,   7,  -7,  -8, -25;
/I:         E1=0; IE=-380; DE=-380;
» More

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2014_11 which contains 547'085 sequence entries.


Total number of hits 23 in 23 different sequences
Number of true positive hits 23 in 23 different sequences
Number of 'unknown' hits
Number of false positive hits
Number of false negative sequences 0
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 100.00 %

Comments [info]

Matrix type [info] protein_domain
Scaling database [info] reversed
Author [info] CJA_Sigrist
Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 1
Feature key [info] DOMAIN
Feature description [info] FYR N-terminal
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
23 sequences

ATX1_ARATH  (Q9C5X4), ATX2_ARATH  (P0CB22), JM703_ORYSJ (Q53WJ1), 
JMJ14_ARATH (Q8GUI6), JMJ15_ARATH (O64752), JMJ16_ARATH (C0SUT9), 
JMJ18_ARATH (F4I6G4), KMT2A_HUMAN (Q03164), KMT2A_MOUSE (P55200), 
KMT2B_HUMAN (Q9UMN6), KMT2B_MOUSE (O08550), KMT2C_HUMAN (Q8NEZ4), 
KMT2C_MOUSE (Q8BRH4), KMT2D_HUMAN (O14686), KMT2D_MOUSE (Q6PDK2), 
MBD9_ARATH  (Q9SGH2), TBRG1_HUMAN (Q3YBR2), TBRG1_MOUSE (Q3UB74), 
TBRG1_RAT   (Q5PQK8), TBRG1_XENTR (Q66IH2), TRR_DROME   (Q8IRW8), 
TRX_DROME   (P20659), TRX_DROVI   (Q24742)
» More


View entry in original PROSITE format
View entry in raw text format (no links)
Direct ScanProsite submission