Entry: PS51543

Forthcoming changes to the profile format
General information about the entry

Entry name [info] FYRC
Accession [info] PS51543
Entry type [info] MATRIX
Date [info] JUL-2011 (CREATED); OCT-2013 (DATA UPDATE); MAR-2014 (INFO UPDATE).
PROSITE Doc. [info] PDOC51542
Associated ProRule [info] PRU00876

Name and characterization of the entry

Description [info] FYR domain FYRC motif profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=83;
/DISJOINT: DEFINITION=PROTECT; N1=6; N2=78;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=2.2525024; R2=0.0088431; TEXT='NScore';
/NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=10960.53279; R2=17.63115; TEXT='HScore';
/CUT_OFF: LEVEL=0; SCORE=990; N_SCORE=11.0; H_SCORE=26405; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=481; N_SCORE=6.5; H_SCORE=19423; MODE=1; TEXT='?';
/DEFAULT: M0=-36; D=-200; I=-200; B1=-1000; E1=-1000; MI=-380; MD=-380; IM=-380; DM=-380;
...
                A    C    D    E    F    G    H    I    K    L    M    N    P    Q    R    S    T    V    W    Y
/I:         B1=0; BI=-380; BD=-380;
/M: SY='G'; M= -41,  15,  35,  18, -64,  55, -37,-124,  19, -23,-115,   7,  22, -55,   5,  -5, -35,-121, -18, -39;
/M: SY='P'; M= -25, -24,  31,  29, -61,  31,-108, -44,  -9, -32,   5,  23,  47, -32, -32,  21,  -9, -53,-127, -39;
/M: SY='G'; M=   7,-121,-109, -43, -20,  46,  15, -37,  32, -35,   8,   2,-117,   2,  36,   1, -18, -27,-120,  -1;
/M: SY='P'; M=-112, -31,-117,-107, -47,-119,-118, -38, -34,   8,-107,-121, 121,-115,-121, -66,-106,  -3,-125,-121;
/M: SY='L'; M=-108, -22, -54, -18, -53, -66,-113,  26,  12,  42,  -8, -51,-121,   7,   0,  -8,   8,  36, -17,   8;
/M: SY='F'; M= -76, -26, -64,-128, 124,-129,-114, -55,-125, -90, -99,-122, -48,-133,-123, -73, -66, -39, -90,   2;
/M: SY='R'; M= -58,-123, -11,  44,-119,-120, -17, -65,  24, -41, -42, -20, -47,  27,  68, -28,   9,  26,-127,-112;
/M: SY='V'; M=-104,-118,-129,-125, -99,-131,-128,  72, -61, -30,  -2,-122,-124,-121, -64, -28, -60,  84,-127, -40;
/M: SY='T'; M= -28,  -5,-108,  -7, -49,-115, -27,   1, -24, -80, -34, -27,-114, -14,  21,  42,  75,  11,  17, -23;
/M: SY='S'; M=  12,  25,  -6, -59,-111,-112,-111, -38,-108,  12,  26,   2,  42, -31, -15,  48,   5,  21,-127, -30;
/M: SY='E'; M=  -4,-123,  51,  67,-121, -36, -10,  -6, -10, -25, -27, -35, -31,   6, -34,  10,  -6, -23,-130,-114;
/M: SY='D'; M= -68,-123,  96,  35,-128, -27, -15,-128, -61,-127,-122,  35, -61, -44, -34,  13,  11,-124,-138, -41;
/I:         I=-22; MD=-42;
/M: SY='D'; M= -45, -28,  64, -43,-135, -58, -16,-134, -16, -55, -14,  38, -35,  20, -28,  -3, -32, -83,-146, -21; D=-22;
/I:         I=-22; MI=0; MD=-42; IM=0; DM=-42;
/M: SY='P'; M= -80, -42, -28,  -9,-140,  -3, -48,-131, -48, -30, -41,-127,  85, -12, -71, -16,-123, -42,  -4,-136; D=-22;
/I:         I=-22; DM=-42;
/M: SY='D'; M= -74,-125,  52,  50,-128,  47,   7, -67,  -3, -66, -42,  11, -29, -99,   1,  -8,   5,-123,-132,-119; D=-22;
/I:         I=-22; DM=-42;
/M: SY='F'; M= -39,-121, -39,  33,  51, -50,   3,  24, -13,   9, -98, -19,-120, -14,   2, -42,   2,  23,-116,  -7; D=-22;
/I:         I=-22; DM=-42;
/M: SY='P'; M= -63,  34, -62,  12,   9, -52, -31,   8,  26, -13,-103, -58,  38,   3, -15,  17,  13,  21,-121,  -4;
/M: SY='F'; M= -77, -45,-126,-123,  71, -57,  37,  50, -35,  -7,  -5,-118,-125,-118,-118, -33, -31,  13,  70,  47;
/M: SY='E'; M= -31, -35, -17,  62, -26,-117, -40,   8,  -7,-109, -37, -39,-112,  17,   9,  31,  27,  21,-126, -46;
/M: SY='G'; M=  34,  -4,  -1, -28, -63,  79,  20, -57, -53,-124,-117, -34,-115,-107, -43,  25,-106,-119,-124, -50;
/M: SY='S'; M=  -2, -12,  35, -16, -37, -43,  -9, -76,  13, -47,-112,  22,  24, -54,  15,  45,  27, -19, -26, -42;
/M: SY='S'; M= -26, -38,  22,-102,-120,-104, -38,-115, -46,-119,-114, -24,-111, -36,-109,  91,  63, -32,-133,-114;
/M: SY='P'; M=  45,  33,-117,-109,-119, -67, -31,  10,-113, -19,  15,-115,  96,-112,-120, -20, -24, -32,-126,-119;
/M: SY='D'; M= -33,-118,  60,  25,-123, -57,  -3,-120, -17, -81, -40,  24, -53, -29, -70,  54,  58,-115,  -1,-114;
/M: SY='E'; M=  30,-120,  29,  41, -57,  16, -39, -32,  23, -59, -33,   8, -43,   1, -21,  14, -20, -23,-127,-115;
/I:         I=-8; MD=-15;
/M: SY='C'; M=  63,  95,-122,-116,-117, -74,-123, -63,-117, -35, -27,-116,  40,-117,-122, -56, -62,  42,-132,-120; D=-8;
/I:         I=-8; MD=-15;
/M: SY='W'; M=-129,-152,-154,-134, -11,-128,-150,-123,-126, -76,-124,-148,-134,-126,-129,-135,-139, -81, 174,  -4; D=-8;
/I:         I=-8; MD=-15;
/M: SY='Q'; M= -17,-135, -14,  -3,-137,-126,-118, -66,  19, -48,-125,  19, -40,  34,  26,  14,  16,-128,-142,-128; D=-8;
/I:         I=-8; MI=0; MD=-15; IM=0; DM=-15;
/M: SY='V'; M= -47, -37,   0,  10, -60, -55, -35,   3, -51, -44,-125,  -4, -64,-128, -15, -27,-126,  26,-153,-134; D=-8;
/I:         I=-8; DM=-15;
/M: SY='I'; M= -20,-140, -57,-138,  14,-145,  30,  43, -73,  12, -36, -63,-143, -47, -68, -67, -60,  -2,-140,-118; D=-8;
/I:         I=-8; DM=-15;
/M: SY='E'; M= -59, -26, -21,  27,-135, -14,   3, -21,   9, -48, -45, -19,   0,  -4, -20, -11, -23, -11,-143, -62; D=-8;
/I:         I=-8; DM=-15;
/M: SY='K'; M=   5,  30, -11, -31,-129, -32,   0,  -8,  38, -30,-117, -57, -26,   4,   9,  -1, -12, -32,-137,-123; D=-8;
/I:         I=-8; DM=-15;
/M: SY='I'; M= -23, -15, -18, -27,-113, -46, -38,  45, -45,  13, -13, -64, -28,  14, -22, -59, -59,  42,-134,-116; D=-8;
/I:         I=-8; DM=-15;
/M: SY='Q'; M= -21, -40, -61,  19,  -1,-127,  22,  24, -69,  10, -13,   6, -65,  44,   3, -71,-112,  20,-126,  -2; D=-8;
/I:         I=-8; DM=-15;
/M: SY='Q'; M= -75, -58,  26,  40, -53, -59,-108, -20,  36, -36, -37,  24,   7,  47, -12, -31,   7, -40,-131,-117; D=-8;
/I:         I=-8; DM=-15;
/M: SY='K'; M=  28,   3, -34,   8,  -1,  -5,-111, -25,  38,  12, -47, -59,-119,-104,  14,  -6,   2, -63,-120,  12; D=-8;
/I:         I=-8; DM=-15;
/M: SY='R'; M= -20,  -8, -15,  -6, -61, -20,-110,  21,  10, -12,   1,  -1,-121,  17,  68, -64, -61,   8,  -9,-111; D=-8;
/I:         I=-8; DM=-15;
/M: SY='R'; M=  10, -12,  15,  -2,-119, -38,-106, -34,  31, -22, -17,  34, -49,  23,  37,  22, -17, -16,-127, -52;
/M: SY='E'; M=  13,  11,  21,  42,   7,-113,  12, -43,  35,-114,  20,  31, -60,  12,  19,   1,-104, -56,-123, -13;
/M: SY='A'; M=  30,-119,  23, -23, -20, -14,  19,  11, -41,  21,  -4,   2, -64,  19, -38,  -5, -52,  17, -10,-107;
/I:         I=-44; MI=0; MD=-84; IM=0; DM=-84;
/M: SY='Q'; M= -17,   3,  -3,  -2,-113,  12, -45, -34,  21,  28, -11,  30,   5,  31,  16, -20,-106, -27, -19, -46;
/M: SY='R'; M= -19, -57,  -2, -13, -29,  11,  33, -62,   8,  13,  18,  -2,  29, -10,  36,   9,  -9, -28,-125,-109;
/M: SY='P'; M= -27, -10,   7, -33,  -8, -25, -25,   2,  22,   3,-104,   5,  48,  12,  14,   4,  -4,   2,-125,-110;
/M: SY='K'; M= -31,  27,   1,  17, -39,  14,   3, -44,  36, -11,   1, -27,  23,   0,  11,   8, -29,  -7,-125, -39;
/M: SY='W'; M= -54, -35,  13,  -9, -24,  15,  -5, -17,  12,  20, -45, -16,  21,   9,  22,   3,   6, -27,  22,-109;
/M: SY='P'; M=  -3, -43, -30, -15,  25, -47,  10, -22,  26, -14, -37, -53,  59,-104,  29,  17, -25,   0, -28, -51;
/M: SY='S'; M=   2,  13, -43,-109,  10, -37,-112,  -8,   5,  20, -12,   4,  39, -27,  -5,  44, -40,   1,-123,-108;
/M: SY='T'; M=   3,   9, -12,   9,   4, -25,-110,   5,  -8,  -1,   9,  21,  24,  -2, -28,  -6,  33, -16,-123, -17;
/M: SY='S'; M=   9,-119, -11, -11,  -1, -10,  -7, -36,   9, -64, -41,   0,  16,   6,  15,  42,  30, -82,-119,  25;
/M: SY='W'; M= -53,-122, -63, -43,  -4,  -8, -56,  56,  -6,   7, -14, -52,   1, -30, -43, -51, -43,  51,  66,-103;
/M: SY='S'; M= -40,   3,  30,-101,-118, -37,-105, -75,  -7, -16,-112,  50, -18,   0,  -8,  74,  -3, -74,   9, -39;
/M: SY='G'; M= -69,-124,  12,-117,-126, 100,-116, -45, -51, -80,-119, -98,-116,-113,-121, -55, -32, -46,-122, -40;
/M: SY='P'; M=   0, -40,   0,  34,  -6,-116,  43, -24,-105,   0, -43, -50,  71,  23, -56,   0,  -3, -28,-124, -16;
/M: SY='D'; M= -28, -30,  71,  68, -57, -72, -12, -21, -44, -81,-115, -14,-112,  30,  -1,   1, -58, -49,  14, -24;
/M: SY='M'; M= -23, -43,-126,-119,  61, -49, -10, -23,-112,  30, 103,-117,-124, -50,  16, -31,-109, -48,-109,  21;
/M: SY='F'; M=-121,-120,-133,-129, 119,-130,-112, -22,-125,  -3, -30,-124,-133,-131,-122,-121,-114, -99, -89,  42;
/M: SY='G'; M= -16,  -1,-112,-121,-128, 104,-118,-133,-116, -55,-119, -99,-116, -32,-123, -60,-114,-127,-122,-124;
/M: SY='F'; M=-116,-118,-132,-125,  76,-132,-115,  -5,-124,  75, -21,-127,-131, -33,-122,-122,-111, -24,-106,   1;
/M: SY='T'; M=   4, -40,  21, -29,-118,  -6, -20,-110, -14, -11,-109,  17, -66, -21, -43,  56,  58, -15,-131,-114;
/M: SY='H'; M= -11,-119,  20,   6, -29,-112,  77, -46, -55,  -4,-105,  64,-117, -29, -20,  18,   8,  -4,-130,  -7;
/M: SY='P'; M= -27, -11,  21,   3,-129, -72, -25,-121,  -7, -79,-116,  14, 105, -14, -14, -13, -40, -54,-129,-122;
/M: SY='T'; M=  27, -38, -15,  13,  26, -42,  14, -36, -11, -22, -27,   5,  16,  -3,  10, -27,  29, -10, -17,   5;
/M: SY='V'; M= -46,-117,-130,-125, -98,-132,-128,  66,-123, -14, -36,-124,-125,-122,-124,-115, -39,  86,-125,   4;
/M: SY='Q'; M=  -1,  -2, -60, -65, -69,-119,  29,  18,  -2,  -5,  31, -49,-119,  63,  24,   1,  -6,  28,-124, -23;
/M: SY='R'; M= -19,-124, -21,  14, -13, -75,   9, -65,  39, -60, -35,  35,-117,  30,  64,  -3, -75,-117,-116,  44;
/M: SY='L'; M=  21,  -6,-121,   6, -56,-124, -33,  29, -65,  65,  18,-121, -39,-111, -34, -71,-107,   0,-120,  -9;
/M: SY='I'; M= -58,-120,-130,-126, -10,-132,-123,  82,-122,  48,  31,-123,-124,-119, -62,-117,   5,  12,-121,-102;
/M: SY='E'; M= -49,-126, -89,  91,-127,-117,-101, -78, -10, -58, -13, -10,-109,  66,  11,  16,-105, -59,-126,-115;
/M: SY='Q'; M=  20, -35, -56,  35,-125, -16,  -8,-121,  15, -43, -55,   8,-112,  75, -22,  49, -30,-116,-126,-113;
/M: SY='L'; M= -50,  -5, -59,-119, -57, -60,-113, -84,-120,  83,  66, -26, -54, -17,-119, -32,-108, -41,  -2,-102;
/M: SY='P'; M= -24,-130,  19,  18,-125, -63, -30, -66, -55, -25,-113, -50, 109, -56, -39,   1, -65, -58,-127, -44;
/M: SY='G'; M= -40,-122,  19, -61,-122,  72,-108,-122,   9, -55,-115,  52, -19,   1, -52,   2, -52, -24,-124,  -9;
/M: SY='A'; M=  65, -36, -62,  -9,  -6, -58,-116,  21, -44, -66,-102,  -5,-117,-108, -38,  24, -42,  38,-124, -42;
/M: SY='D'; M= -19, -35,  61,  43, -57, -75,  50, -40,  10, -31,-111,  -6, -38,   7,  34, -16, -29, -33, -15,-110;
/M: SY='K'; M=   8,-120, -17, -19, -57, -49,  18, -68,  56, -39, -55,  18,   8,   6,  15,  30,  16, -41,  -7, -30;
/M: SY='C'; M= -29, 131, -63, -69, -47, -55,-120,  -6, -75,  29,   8,-115, -33, -42,-123, -10, -33,-102,-132, -47;
/M: SY='S'; M=   8,-117, -61,  -5, -26, -19, -31, -34,  28, -27,-107,  -2,  -5,  -2,   5,  46,  38,   7,-126,-111;
/M: SY='N'; M= -55,  -7,  40,  -5,-121,   9, -17, -14,  54, -74, -45,  54, -51, -23,  18,  -9, -27, -43, -10, -35;
/M: SY='Y'; M= -34,-126,-116, -14,  26, -70, -27, -64, -54, -27, -37,-116, -36, -27, -32, -24, -52, -46,   4, 121;
/I:         I=-44; MI=0; MD=-84; IM=0; DM=-84;
/M: SY='W'; M= -33, -31, -54,  -7,-114, -73,-109,   3,  47, -22, -31,  12, -64,  51,  35,   4,  -7,  -3,  77,-107;
/M: SY='F'; M= -31,-124, -47, -46,  70, -50,  -9, -48,  -6, -57,  20,  17,  44,   7,  50, -36, -24, -79,  35, -25;
/M: SY='R'; M=  -4, -38,-112, -13, -45,-119, -37,-103,  45,  26, -28, -62, -64,  26,  51, -15,  -2,   7,  47, -42;
/M: SY='F'; M=  -7, -26,  -5,  19,  58, -81,  17, -27,  12, -25,-104,  16,  13, -65, -41,  -9, -16, -19,-109,  54;
/I:         E1=0; IE=-380; DE=-380;
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Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2014_04 which contains 544'996 sequence entries.


Total number of hits 19 in 19 different sequences
Number of true positive hits 19 in 19 different sequences
Number of 'unknown' hits
Number of false positive hits
Number of false negative sequences 0
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 100.00 %

Comments [info]

Matrix type [info] protein_domain
Scaling database [info] reversed
Author [info] CJA_Sigrist
Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 1
Feature key [info] DOMAIN
Feature description [info] FYR C-terminal
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
19 sequences

ATX1_ARATH  (Q9C5X4), ATX2_ARATH  (P0CB22), JMJ14_ARATH (Q8GUI6), 
KMT2A_HUMAN (Q03164), KMT2A_MOUSE (P55200), KMT2B_HUMAN (Q9UMN6), 
KMT2B_MOUSE (O08550), KMT2C_HUMAN (Q8NEZ4), KMT2C_MOUSE (Q8BRH4), 
KMT2D_HUMAN (O14686), KMT2D_MOUSE (Q6PDK2), MBD9_ARATH  (Q9SGH2), 
TBRG1_HUMAN (Q3YBR2), TBRG1_MOUSE (Q3UB74), TBRG1_RAT   (Q5PQK8), 
TBRG1_XENTR (Q66IH2), TRR_DROME   (Q8IRW8), TRX_DROME   (P20659), 
TRX_DROVI   (Q24742)
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PDB
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1 PDB

2WZO

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