PROSITE entry PS51642
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General information about the entry
| Entry name [info] | HEMOPEXIN_2 |
| Accession [info] | PS51642 |
| Entry type [info] | MATRIX |
| Date [info] |
01-MAY-2013 CREATED;
01-OCT-2013 DATA UPDATE; 29-MAY-2024 INFO UPDATE. |
| PROSITE Doc. [info] | PDOC00023 |
| Associated ProRule [info] | PRU01011 |
Name and characterization of the entry
| Description [info] | Hemopexin repeat profile. |
| Matrix / Profile [info] |
/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=47; /DISJOINT: DEFINITION=PROTECT; N1=1; N2=47; /NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=2.1196651; R2=0.0077764; TEXT='NScore'; /CUT_OFF: LEVEL=0; SCORE=821; N_SCORE=8.5; MODE=1; TEXT='R'; /CUT_OFF: LEVEL=-1; SCORE=564; N_SCORE=6.5; MODE=1; TEXT='RR'; /DEFAULT: M0=-21; D=-150; I=-150; B1=-1000; E1=-1000; MI=-380; MD=-380; IM=-380; DM=-380; ... A C D E F G H I K L M N P Q R S T V W Y /I: B1=0; BI=-380; BD=-380; /M: SY='P'; M= -46, -79, -15, 17, -24, 9, 38, -50, -34, -26, -40, -37, 86, -48, -17, -15, -20, 14, -79, -52; /M: SY='D'; M= -21, -28, 36, 5, -51, 25, -3, -13, 4, -44, -65, 25, -9, -4, -26, 31, 4, -32, 17, -1; /M: SY='P'; M= -23, 10, -19, 1, -73, 4, 45, -33, 36, -38, -33, 28, 46, -10, 10, 3, -23, -22, -48, -39; /M: SY='C'; M= -56, 58, -71, -77, 33, -72, -77, 49, -65, 14, -11, -73, -42, -50, -59, -44, -3, 57, -74, -44; /M: SY='D'; M= -64, -79, 107, -11, -84, -11, 4, -82, -50, -58, -77, -8, -67, -4, -62, -14, -14, -79, -96, -53; /M: SY='A'; M= 82, -4, -19, -60, -76, 14, -53, -62, -63, -70, -64, -48, -6, -59, -68, 15, -5, -48, -10, -71; /M: SY='A'; M= 72, -65, -43, -53, 8, -52, -43, 3, -49, -29, -54, -12, -56, -63, -69, -5, -25, 36, -75, -55; /M: SY='F'; M= -12, -70, -78, -74, 75, -78, -63, -14, -70, 26, 12, -62, -60, -71, -19, -36, 3, 21, -54, 53; /M: SY='E'; M= -31, 38, 11, 40, -18, -53, 0, -55, -36, -38, -42, -21, -14, 24, 19, 24, -1, 14, -23, 28; /I: I=-24; MD=-60; /M: SY='W'; M= -18, 55, 23, -37, 14, -40, -23, -10, -57, -18, 29, 6, -77, -47, -4, 1, 0, -14, 72, 17; D=-24; /I: I=-24; MD=-60; /M: SY='E'; M= -48, -60, 40, 41, -69, -43, 21, -48, -25, -71, -33, -47, 40, -41, -14, -22, -27, -44, -28, -39; D=-24; /I: I=-24; MI=0; MD=-60; IM=0; DM=-60; /M: SY='Q'; M= -42, -44, -13, -29, -56, -21, -20, -38, -4, 0, -45, -19, 6, 9, -26, -24, -50, -65,-100, -86; D=-24; /I: I=-24; DM=-60; /M: SY='R'; M= -45, -83, 28, -21, -42, 10, 12, -49, -24, -48, -72, 39, -22, 5, 48, -16, -5, -58, -87, -28; D=-24; /I: I=-24; DM=-60; /M: SY='G'; M= -35, -78, 36, 16, -82, 63, 26, -84, 3, -82, -72, 24, 1, 2, -21, -17, -62, -57, -82, -66; D=-24; /I: I=-24; DM=-60; /M: SY='H'; M= -25, -76, -33, 37, -6, 13, 61, -59, 43, -45, -56, 4, -59, -6, 14, -10, -5, -64, -44, 21; /M: SY='V'; M= 1, -68, -69, -70, 19, -74, 22, 30, -62, 11, 12, -30, -73, -55, -61, -5, 37, 48, -74, -3; /I: I=-31; MI=0; MD=-79; IM=0; DM=-79; /M: SY='Y'; M= -69, 22, -74, -73, 55, -79, 47, -12, -58, 8, -4, -70, -81, -66, -41, -67, -35, -24, -12, 101; /M: SY='F'; M= -11, 25, -83, -79, 95, -79, -70, 26, -76, 12, -3, -74, -81, -79, -75, -14, -61, -1, -54, -28; /M: SY='F'; M= -32, -6, -85, -81, 110, -81, -68, 18, -77, -27, -18, -75, -83, -83, -75, -45, -49, -25, -46, 4; /M: SY='K'; M= -28, -61, -57, -48, -71, -60, 30, -29, 76, -42, -61, 9, -67, 24, 32, 19, -38, -20, -75, -14; /M: SY='G'; M= -30, -77, 51, -2, -83, 87, -65, -88, -48, -84, -76, -17, -67, -38, -42, -47, -64, -82, -41, -75; /M: SY='N'; M= -27, -41, 43, -8, -77, -15, 37, -67, -4, -46, -66, 50, 19, 28, 36, 13, -7, -74, -35, -65; /M: SY='H'; M= -59, -78, -14, 0, 29, -23, 59, -29, 32, -42, -6, -21, -70, 49, 23, 6, -60, -57, 36, 28; /M: SY='Y'; M= -61, 16, -77, -64, 63, -80, -22, 13, -55, 6, -25, -72, -81, 18, -68, -67, -46, 23, -48, 85; /M: SY='W'; M= -32, -86, -87, -77, 38, -74, -50, -49, -71, -16, -30, -82, -80, -69, -72, -24, -64, -56, 151, 70; /M: SY='R'; M= -8, -76, -1, 4, -24, -71, -6, -41, 33, -7, -18, -26, -71, -13, 69, -2, -44, 6, 19, -41; /M: SY='Y'; M= -62, -73, -79, -76, 68, -23, -62, 18, -35, 13, -14, -73, -72, -49, -33, -55, -32, 30, 19, 69; /I: I=-36; MI=0; MD=-90; IM=0; DM=-90; /M: SY='D'; M= -30, -76, 80, -28, -32, -1, 38, -43, -19, -63, -70, 38, -34, 0, 9, 10, -4, -74, -88, -64; /I: I=-17; MD=-44; /M: SY='P'; M= -48, -82, -36, 20, -19, 15, -46, -39, -15, -13, -10, 13, 63, -38, -44, 4, -23, -28, -27, -27; D=-17; /I: I=-17; MD=-44; /M: SY='H'; M= -27, -81, -22, -4, -13, -15, 49, -62, 14, -42, 9, 38, -76, 30, 1, -10, -28, -15, -22, 2; D=-17; /I: I=-17; MD=-44; /M: SY='T'; M= -20, -81, -20, -40, -81, -41, -59, -62, 15, -15, -57, 4, -78, 6, 23, 21, 42, -51, -91, -76; D=-17; /I: I=-17; MI=0; MD=-44; IM=0; DM=-44; /M: SY='M'; M= -29, 7, -63, -63, -61, -78, -44, -28, -30, 17, 46, -1, -44, -34, -42, -66, -42, 33, -92, -15; D=-17; /I: I=-17; DM=-44; /M: SY='D'; M= -51, -85, 38, 23, -61, -32, 13, -31, 18, -9, -15, -42, -5, 19, 3, -35, -34, -17, -85, -6; D=-17; /I: I=-17; DM=-44; /M: SY='P'; M= -2, -80, -1, 11, -77, -10, -57, -28, 15, -34, -6, -8, 58, -23, 8, 5, -33, -10, -82, -33; D=-17; /I: I=-17; DM=-44; /M: SY='G'; M= -24, -47, 21, -43, -9, 48, -26, -13, -12, -31, -54, -31, 6, -1, -29, -9, 6, 4, 18, -53; D=-17; /I: I=-17; DM=-44; /M: SY='Y'; M= -52, -81, -21, 7, -6, -4, 17, -44, -3, -45, -61, -45, 22, -32, -21, -11, -3, -22, -20, 87; D=-17; /I: I=-17; DM=-44; /M: SY='P'; M= -31, -84, -27, -19, -27, -55, -16, -23, -18, -31, -57, -67, 97, -55, 24, -2, -40, -11, -80, -72; D=-17; /I: I=-17; DM=-44; /M: SY='K'; M= -27, -77, -13, -6, -20, -21, 7, -32, 65, -23, 15, -13, -50, -8, 39, -18, -15, -31, 20, -44; D=-17; /I: I=-17; DM=-44; /M: SY='L'; M= -34, -73, -2, -12, -23, -28, -39, -55, -4, 39, -17, -16, 37, 9, 12, 20, 8, -23, -75, -17; /M: SY='I'; M= -1, -72, -26, -39, -41, -73, -17, 71, 0, 7, -3, -20, -72, -51, -21, -16, -2, 26, -77, -59; /I: I=-45; MD=-115; /M: SY='S'; M= 14, -72, -2, 12, -57, -26, 22, -35, 18, -27, -62, 4, -35, 18, -1, 45, 15, -28, -47, -29; D=-45; /I: I=-45; MI=-115; IM=-115; DM=-115; /M: SY='E'; M= 4, -73, 31, 39, -47, -41, -2, -52, 20, -37, -65, 23, -24, 16, 8, 29, 5, -39, -80, -27; /M: SY='Y'; M= -54, -49, 28, 15, 25, 7, -1, -54, 1, 7, -8, -32, -45, -27, -13, 7, 11, -3, 20, 30; /M: SY='W'; M= -45, -79, -73, -49, 74, 10, -76, -33, -55, -18, -37, -58, -66, -57, -60, -35, -4, -22, 131, -3; /M: SY='P'; M= -54, -78, -67, -37, 28, -6, -44, -4, -5, 12, 33, -39, 79, -35, -7, -9, -22, -43, 33, -57; /M: SY='G'; M= -18, -23, -13, 13, -9, 51, -11, -35, -27, -51, -43, 11, 32, 31, -15, 5, 9, -50, -45, -66; /M: SY='C'; M= -20, 85, -67, -52, 0, -46, -70, 25, -43, 30, -7, -47, 36, 31, -42, -51, -49, 7, -77, -62; /I: E1=0; IE=-380; DE=-380;» more |
Numerical results [info]
| Total number of hits | 433 in 104 different sequences |
| Number of true positive hits | 433 in 104 different sequences |
| Number of 'unknown' hits | 0 |
| Number of false positive hits | 0 |
| Number of false negative sequences | 0 |
| Number of 'partial' sequences | 1 |
| Precision (true positives / (true positives + false positives)) | 100.00 % |
| Recall (true positives / (true positives + false negatives)) | 100.00 % |
Comments [info]
| Taxonomic range [info] | Eukaryotes, Eukaryotic viruses |
| Maximum number of repetitions [info] | 8 |
| Matrix type [info] | protein_domain |
| Scaling database [info] | reversed |
| Author [info] | CJA_Sigrist |
| Feature key [info] | REPEAT |
| Feature description [info] | Hemopexin |
| Version [info] | 1 |
Cross-references [info]
| UniProtKB/Swiss-Prot True positive sequences |
104 sequences
ALB2_LATSA (D4AEP7), ALB2_PEA(P08688), D2MP_DROME (Q8MPP3), HEMO_BOVIN (Q3SZV7), HEMO_DANRE (Q6PHG2), HEMO_HUMAN (P02790), HEMO_MOUSE (Q91X72), HEMO_PIG(P50828), HEMO_PONAB (Q5R543), HEMO_RABIT (P20058), HEMO_RAT(P20059), HE_HEMPU(P91953), HE_PARLI(P22757), MMP10_HUMAN (P09238), MMP10_MOUSE (O55123), MMP10_RAT (P07152), MMP11_HUMAN (P24347), MMP11_MOUSE (Q02853), MMP11_RAT (Q499S5), MMP11_XENLA (Q11005), MMP12_HUMAN (P39900), MMP12_MOUSE (P34960), MMP12_RABIT (P79227), MMP12_RAT (Q63341), MMP13_BOVIN (O77656), MMP13_HORSE (O18927), MMP13_HUMAN (P45452), MMP13_MOUSE (P33435), MMP13_RABIT (O62806), MMP13_RAT (P23097), MMP13_XENLA (Q10835), MMP14_BOVIN (Q9GLE4), MMP14_HUMAN (P50281), MMP14_MOUSE (P53690), MMP14_PIG (Q9XT90), MMP14_PONAB (Q5RES1), MMP14_RABIT (Q95220), MMP14_RAT (Q10739), MMP15_HUMAN (P51511), MMP15_MOUSE (O54732), MMP16_HUMAN (P51512), MMP16_MOUSE (Q9WTR0), MMP16_RAT (O35548), MMP17_HUMAN (Q9ULZ9), MMP17_MOUSE (Q9R0S3), MMP18_XENLA (O13065), MMP19_HUMAN (Q99542), MMP19_MOUSE (Q9JHI0), MMP1A_MOUSE (Q9EPL5), MMP1B_MOUSE (Q9EPL6), MMP1_AQUCT (Q11133), MMP1_BOVIN (P28053), MMP1_HORSE (Q9XSZ5), MMP1_HUMAN (P03956), MMP1_PIG(P21692), MMP1_RABIT (P13943), MMP20_BOVIN (O18767), MMP20_HUMAN (O60882), MMP20_MOUSE (P57748), MMP20_PIG (P79287), MMP21_CYNPY (Q90YC2), MMP21_DANRE (A0A0N9E2K8), MMP21_HUMAN (Q8N119), MMP21_MOUSE (Q8K3F2), MMP21_XENLA (O93470), MMP24_HUMAN (Q9Y5R2), MMP24_MOUSE (Q9R0S2), MMP24_RAT (Q99PW6), MMP25_HUMAN (Q9NPA2), MMP25_MOUSE (Q3U435), MMP27_HUMAN (Q9H306), MMP27_TUPBE (Q9GKE1), MMP28_HUMAN (Q9H239), MMP2_BOVIN (Q9GLE5), MMP2_CHICK (Q90611), MMP2_HUMAN (P08253), MMP2_MOUSE (P33434), MMP2_RABIT (P50757), MMP2_RAT(P33436), MMP3_CANLF (Q6Y4Q5), MMP3_HORSE (Q28397), MMP3_HUMAN (P08254), MMP3_MOUSE (P28862), MMP3_RABIT (P28863), MMP3_RAT(P03957), MMP8_HUMAN (P22894), MMP8_MOUSE (O70138), MMP8_RAT(O88766), MMP9_BOVIN (P52176), MMP9_CANLF (O18733), MMP9_HUMAN (P14780), MMP9_MOUSE (P41245), MMP9_RABIT (P41246), MMP9_RAT(P50282), MMPA_CAEEL (G5EGM1), MMPC_CAEEL (G5EBU3), MMP_HVAVE (A4KX75), MMP_TNAVC (Q06VC5), PRG4_HUMAN (Q92954), PRG4_MOUSE (Q9JM99), VTNC_HUMAN (P04004), VTNC_MOUSE (P29788), VTNC_PIG(P48819), VTNC_RABIT (P22458)» more
|
| UniProtKB/Swiss-Prot 'Partial' sequences |
1 sequence
ALB2_LENCU (P86782) |
| PDB [Detailed view] |
26 PDB
1CK7; 1FBL; 1GEN; 1GXD; 1HXN; 1ITV; 1PEX; 1QHU; 1QJS; 1RTG; 1SU3; 2CLT; 2JXY; 2MQS; 3BA0; 3C7X; 3LP9; 4AUO; 4FU4; 4FVL; 4G0D; 4RT6; 6CLZ; 6CM1; 6O5E; 7RJ9 » more |