To improve security and privacy, we are moving our web pages and services from HTTP to HTTPS.
To give users of web services time to transition to HTTPS, we will support separate HTTP and HTTPS services until the end of 2017.
From January 2018 most HTTP traffic will be automatically redirected to HTTPS. [more...]
View this page in https
Entry: PS51644

General information about the entry

Entry name [info] HTH_OST
Accession [info] PS51644
Entry type [info] MATRIX
Date [info] 01-MAY-2012 CREATED; 01-MAY-2012 DATA UPDATE; 22-NOV-2017 INFO UPDATE.
PROSITE Doc. [info] PDOC51644
Associated ProRule [info] PRU00975

Name and characterization of the entry

Description [info] OST-type HTH domain profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=74;
/DISJOINT: DEFINITION=PROTECT; N1=1; N2=74;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=2.0157390; R2=0.0071836; TEXT='NScore';
/CUT_OFF: LEVEL=0; SCORE=1098; N_SCORE=9.9; MODE=1; TEXT='R';
/CUT_OFF: LEVEL=-1; SCORE=653; N_SCORE=6.7; MODE=1; TEXT='RR';
/DEFAULT: M0=-33; D=-150; I=-150; B1=-1000; E1=-1000; MI=-380; MD=-380; IM=-380; DM=-380;
...
                A    C    D    E    F    G    H    I    K    L    M    N    P    Q    R    S    T    V    W    Y
/I:         B1=0; BI=-380; BD=-380;
/M: SY='S'; M=   7, -38,  25,  11, -42, -49, -47,   6,  -4, -14, -17,  -6,  11,  26,  -8,  35, -12,  -1, -66, -64;
/M: SY='L'; M= -30, -33,  28, -44, -37, -89,-142,  11,  11,  39,  10,  -9,  38, -25,   3,  -9, -14,  -6, -61, -72;
/M: SY='E'; M=  -6, -75,  26,  48, -80, -66, -47, -49,  29,-104, -36,   5,  15,  16,  27,  24, -11, -30, -61, -22;
/M: SY='E'; M=  -4, -64,  37,  47, -33, -60, -25, -16,  19, -10, -35, -23, -18,  27,  16, -24,  -1, -20, -22, -35;
/M: SY='L'; M=   3,   0, -97, -80,  48,-157,-151,  26,-152,  54, -56,-154,  -2,-150,-111, -93, -46,  44, -64, -57;
/M: SY='K'; M=   8, -54, -48,   8, -55, -57, -10,  11,  47,  -7, -13,-136, -41,  21,  26,  -2,   9,  12, -37,-103;
/M: SY='R'; M=  17, -13,   6,  23, -33, -41, -20, -50,  31, -37, -35,  22,  -6,  22,  39,  16, -13, -83,-155, -42;
/M: SY='Q'; M=  -3, -56,  -6,  39, -17, -52, -18, -10,  -2,  28,  20, -13,-147,  44,  17, -96, -13, -10, -34, -25;
/M: SY='I'; M= -47, -46,-161,-155, -31,-162,-153,  67,-110,  59,  24,-155,-156,-150, -74,-148, -28,  41,-152,-133;
/M: SY='R'; M= -19,  -8, -52,   0, -57, -72,  11,  -8,  30,   5, -52, -48, -75,  27,  63, -38,  -5,  10,-151,   5;
/M: SY='E'; M=  18,-151,  27,  44, -85, -50, -44,-102,  37, -45, -35,   7, -77,  30,  14,  33, -11, -98, -69, -66;
/M: SY='L'; M=  32, -11, -95, -88, -45, -78,-150,  47,-150,  59,  -7, -66,-153, -77,-151, -23, -27,  21,-153,-136;
/M: SY='L'; M= -42, -15,-159,-109, -22,-160, -86,  41,-110,  72,   0,-155, -95,-148, -89, -47, -35,  35, -18, -55;
/M: SY='E'; M= -13, -25,  24,  32, -81, -42, -33, -11,  27, -20,  -8,   8,-103,  27,  23,  20,   6,  -9, -39,-142;
/I:         I=-25; MI=0; MD=-63; IM=0; DM=-63;
/M: SY='S'; M=  20, -45,  -4,  25, -87, -38, -19, -65,  19, -32,   6,  -7, -83,  28, -11,  59,  -4, -54, -33, -27;
/M: SY='H'; M=  14,  -7,  42,   6, -15, -34,  62,-100, -15, -92, -43,  36,-147,   9,   6,  12, -30, -78, -18,  50;
/M: SY='P'; M= -27, -31,  49,  29,-157, -11,  -5,-154,  30,-125, -45,   8,  69,  -3, -24,  20, -39, -81,-159, -62;
/M: SY='N'; M= -32, -38,  55,  29,-153,  32,  -6,-120, -21, -85, -87,  55, -48,  -2, -15,  36, -37,-152,-159,  -7;
/M: SY='G'; M= -63,  14, -52, -49, -64,  86, -60,-111,  -6,-124,-147, -87,  32, -21, -14,  -6, -19, -40,  -4, -99;
/I:         I=-33; MI=0; MD=-84; IM=0; DM=-84;
/M: SY='W'; M= -48, -55,-160,-153, -19,-121,-153,  47,-150,  30,  49,-154, -65, -77,-152, -41, -12,  52, 100, -10;
/M: SY='W'; M=  24, -48, -14, -43,   0, -54, -24, -69, -36,   7, -85,  18,  46, -23, -22,  27,  19, -63,  84, -23;
/M: SY='L'; M=   5,   7, -95, -86,   7, -60,   2,  16, -75,  59,  41,  -9, -24, -57, -78, -11,-136,   9,-149,  -9;
/M: SY='S'; M=  11, -85, -11, -27, -25,  11,  25, -63, -27,  15, -51, -13, -44, -49, -42,  72, -15, -58, -28, -60;
/I:         I=-42; MI=0; MD=-106; IM=0; DM=-106;
/M: SY='Q'; M=  14, -37,  25,  33,-105, -31,  -2, -49,  19, -41,   5,  15, -59,  48,  24,  11, -16, -41, -78, -50;
/M: SY='L'; M= -81, -65,-117,-156,  53,-162,-151,  39,-155,  68, -83,-157,-159,-152,-154,-109, -84,  41,-144, -64;
/M: SY='P'; M= -27, -48, -46,   8,-110,  51, -35, -33,  36, -25, -41, -26,  62,  -7,  -1, -25, -37, -48, -57, -67;
/M: SY='Q'; M=  -4, -92,  17,   6, -70, -22, -61, -73,  23, -65, -65,  38,  -7,  59,   9,  40,   7, -55,-157, -62;
/M: SY='D'; M=  13, -11,  30,  27, -21,-119,  23,  -7, -29,  18,  22, -17,-148,  21,   2, -34,  -8, -23, -18,  25;
/M: SY='Y'; M= -94,-153,-155,-154,  46,-158, -21,  29,-149,  35,  40, -75,-159,-145,-147,-147,-106, -39, -62, 106;
/M: SY='K'; M= -27, -43, -99,   8, -35, -32,  26, -18,  46, -12, -11,  -4,-119,  37,  45,  12,  -7, -30,-151,  -2;
/M: SY='K'; M= -17,-153,  13,  21,-101, -84,  -7,-112,  62, -47, -25,  30,-144,  32,  50,   1, -44, -62, -15, -55;
/M: SY='K'; M= -20, -15,-139,  -2, -44,-116,  37,  -8,  44,  14,  35, -13,-147,  30,  36, -46,  11,  -9, -31, -35;
/M: SY='Y'; M= -65, -13,  21, -11,  68,-110,  29, -28, -17, -45,  -5, -22,-107,   7, -30, -19,   3, -40, -35,  78;
/M: SY='P'; M= -45,-155, -60, -63,-112,  66, -16, -87,  11,-109, -90,   6,  78, -37, -22,  17, -46, -64,-155, -69;
/I:         I=-26; MD=-67;
/M: SY='E'; M= -61, -17, -59,  34, -39, -77,  17,-112,  18, -80, -62, -51, -80,  -3,  28, -37, -37, -33,-167,  17; D=-26;
/I:         I=-26; MI=0; MD=-67; IM=0; DM=-67;
/M: SY='D'; M= -18, -86,  55,  10, -82, -11,  -2, -71, -13, -90,-148,  -2,  55,  28, -52,  25,  -6, -38, -17,-148; D=-26;
/I:         I=-26; DM=-67;
/M: SY='F'; M= -83,   8,-163,-157,  95,-161,-148,  16,-155,  57,  -2,-100, -81,-156,-113,-152,-142, -33,  17,-113;
/M: SY='D'; M= -67, -15,  82, -22,-156, -64,   4, -97, -17, -84, -36,  40,  63, -27,   3,   8, -85, -48,-164, -39;
/M: SY='P'; M= -20, -43, -97,  23,  11,-100,  19, -29, -65,  -1, -46, -67,  74, -25, -87,  -1, -15,  27, -19,  36;
/M: SY='R'; M=  -7, -53,  -3, -19, -99, -25,  29, -82,  37, -76, -43, -24, -98,  17,  76,  21,  -6, -46,-155, -28;
/M: SY='N'; M=  -8,-151,  41,  13, -37, -20,   6, -44,   6, -39, -87,  56, -56,  20,  -5,   6,   2, -11,  29, -15;
/I:         I=-19; MD=-49;
/M: SY='Y'; M=-150, -34,-114,-154,  53,-121,  19, -66,-150,  38, -33, -85,-163, -90, -89, -62,-144, -79, -25, 108; D=-19;
/I:         I=-19; MD=-49;
/M: SY='G'; M=-134,-160, -61, -75,-165, 100, -47,-171, -69, -93,-157, -46, -94, -42,-157, -90,-115,-123,-158,-160; D=-19;
/I:         I=-19; MI=0; MD=-49; IM=0; DM=-49;
/M: SY='Y'; M= -44,  35,-158,-117,  78, -60,  32,-108, -96, -74,-135,-107,-165, -84, -80, -49, -89,  -6, -49,  94; D=-19;
/I:         I=-19; DM=-49;
/M: SY='S'; M=  -6,  15,  -8, -43, -87, -55, -74, -67,  36, -50, -28,   8,   3,  -7,  23,  40,  10, -29, -56,   7; D=-19;
/I:         I=-19; DM=-49;
/M: SY='K'; M= -70, -66,   0, -63, -83, -49, -36,-155,  70,-112,-147,  21, -34,  -9,  18,  54,  17,-116,-160, -97; D=-19;
/I:         I=-19; DM=-49;
/M: SY='L'; M= -53, -60,-162,-156,  51,-162, -92,   1,-155,  74,  37, -67, -57, -96,-108,-116, -25, -14, -52, -97; D=-19;
/I:         I=-19; DM=-49;
/M: SY='S'; M= -25,-150, -16,  27, -31, -19, -74,  -4, -13, -13,   4, -29, -60,  13, -11,  59,  25, -25, -71, -74; D=-19;
/I:         I=-19; DM=-49;
/M: SY='D'; M= -10, -53,  73,  54,-105, -68,  25,-154,   5, -84, -45,  -5, -12,  16, -18,  16,  -6, -73,-162, -71;
/M: SY='L'; M= -60,-147,-108,-153,  69,-120,-144, -15,-152,  74,  46, -58,-159, -38,-151,-113, -66, -31,-139, -25;
/M: SY='L'; M= -47, -58,-161, -91,  11,-162,-151,  52,-111,  67,  18,-156,-157,-150,-153,-149, -65,  41,-150,-130;
/M: SY='E'; M=  -4, -61,   6,  44, -41, -20, -25, -61,  40, -32, -33,  -6, -78,  38,  41,  16, -33, -52,-155,-142;
/M: SY='S'; M=  43, -11,  23,   6, -85, -58,  -7, -32,  22, -36, -47,  -7,-144, -34, -13,  54,  -4, -80,   6, -45;
/M: SY='M'; M=  -4,   5, -55, -35,  -4,-118, -18,  40, -71,  39,  67, -61, -76, -22, -40, -28,  13,  -3,  24,   0;
/I:         I=-23; MD=-58;
/M: SY='P'; M= -14, -30, -15, -21,-163, -33, -15, -91,   2, -59, -39, -32,  83,   2, -23,  21, -20, -66,-166,-157; D=-23;
/I:         I=-23; MI=0; MD=-58; IM=0; DM=-58;
/M: SY='D'; M= -76, -85,  82,  15, -24,  22,  34,-163, -21,-131, -90,  32, -82, -19, -31, -27, -47,-160,-167, -39; D=-23;
/I:         I=-23; DM=-58;
/M: SY='I'; M= -27,-149, -38, -34,  -7, -18, -19,  41, -27,  24, -10, -15, -53, -33, -35, -40,  20,  41, -28,  19;
/M: SY='V'; M= -29,  53, -65, -52,  59, -53,-150,  16, -73,  13, -33, -51, -66,-151, -64, -80, -52,  64,-146,   1;
/M: SY='E'; M= -34, -61,  12,  56, -68, -68,  21, -21,  19, -38, -60, -78,-143,  28,  25,  -1,  26,   9,  -9, -51;
/M: SY='I'; M= -73, -64, -92, -78,   0,-120, -70,  56,-110,  35,  22, -79, -48,-147,  -3, -88,  12,  56, -58, -66;
/M: SY='E'; M= -52, -47,   7,  48,-111, -64,  16,  -8,  34, -63, -19, -26, -70,  39,  14,  -2,   9,   9, -38,   8;
/M: SY='Q'; M= -79,   4,  22,  22, -36,   0,   3, -29,  25, -72, -48,  10, -14,  31,  30,   2,   4, -24,  24,   7;
/M: SY='P'; M= -46, -34,  31,  16, -49,   8,  -4, -18,  16, -32, -38,   0,  34,  17,  10,  14, -17, -11, -32, -20;
/I:         I=-29; MD=-75;
/M: SY='P'; M= -46, -85,   2,  27, -53,  33,  -9, -67, -21, -32, -50,  29,  42, -34,  16,  -5, -11, -71,-161, -57; D=-29;
/I:         I=-29; MI=0; MD=-75; IM=0; DM=-75;
/M: SY='G'; M= -22, -54,  26,   3,-113,  43,  13,-114,  21, -91,  -3,  28,  19, -10, -17,  33,  -5,-150,-158, -40;
/M: SY='G'; M= -26,-152,   5, -10, -28,  50,   2,-150,  21,-103, -20,  40, -27,  34,  -9,  14,  -5, -28,-155, -47;
/M: SY='Q'; M= -27, -84,  23,   5,-115, -20,  32,   1,   3, -44, -39,  36,  -7,  50,  11,  -8,  21,  -9, -18,-141;
/M: SY='W'; M=  -9,  28,-109, -64,   7, -78,   0,  24,   6,   9,  -6, -68, -12,-143, -14, -74, -12,  39,  74,  35;
/M: SY='Y'; M= -53, -24, -79, -36,  20,-105,  26,  27, -23,  16,  34,-145, -71,  -7,   5, -24,  -3,  28,  30,  49;
/M: SY='V'; M=  -3, -22,-107,-150, -33,-101, -49,  51, -95,  22, -41,-151, -43,  -9, -30, -36, -43,  69,-155, -35;
/M: SY='Y'; M= -33,   8, -26, -57,  16, -43,  15, -18,  16,   0,-133, -35,-103, -13,  52,  16, -15, -20, -14,  52;
/M: SY='P'; M=  15, -97,   2, -24, -61, -41,   1,  16, -32,  34, -10, -29,  44, -39,  -5, -24, -16,   4, -10, -78;
/M: SY='K'; M=   3,  -7, -40, -32, -45, -83,   0, -30,  57, -43, -48,   8,  14,  -7,  36,   5, -22,   6, -58, -24;
/M: SY='P'; M= -16, -61,  27,  22,-107,  -8, -61, -94,  27, -46, -30,  13,  31, -53,  15,  17,   0, -15, -22, -15;
/I:         E1=0; IE=-380; DE=-380;
» more

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2017_11 which contains 556'196 sequence entries.


Total number of hits 117 in 33 different sequences
Number of true positive hits 117 in 33 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 0
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 100.00 %

Comments [info]

Matrix type [info] protein_domain
Scaling database [info] reversed
Author [info] CJA_Sigrist
Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 8
Feature key [info] DOMAIN
Feature description [info] HTH OST-type
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
33 sequences

C3H18_ARATH (Q9SJ41    ), C3H51_ORYSJ (Q84ZT0    ), C3H54_ORYSJ (Q6ZK57    ), 
LRR2_PLAF7  (C6KSS5    ), MARF1_BOVIN (E1BP74    ), MARF1_CHICK (E1BZ85    ), 
MARF1_HUMAN (Q9Y4F3    ), MARF1_MOUSE (Q8BJ34    ), MARF1_RAT   (Q8VIG2    ), 
MARF1_XENTR (B2GUN4    ), OSKA_DROME  (P25158    ), OSKA_DROVI  (Q24741    ), 
TDRD5_AILME (D2H3M0    ), TDRD5_BOVIN (E1BPH3    ), TDRD5_CANLF (E2QTD3    ), 
TDRD5_DANRE (Q1L981    ), TDRD5_HUMAN (Q8NAT2    ), TDRD5_MOUSE (Q5VCS6    ), 
TDRD5_RAT   (B4F7C4    ), TDRD5_XENLA (A1L1H3    ), TDRD5_XENTR (A0JM98    ), 
TDRD7_AILME (D2H0H6    ), TDRD7_BOVIN (A6QLE1    ), TDRD7_CANLF (E2RDV1    ), 
TDRD7_CHICK (E1C3S7    ), TDRD7_HUMAN (Q8NHU6    ), TDRD7_MOUSE (Q8K1H1    ), 
TDRD7_PONAB (Q5RAH6    ), TDRD7_RAT   (Q9R1R4    ), TDRD7_XENLA (Q6NU04    ), 
TDRD7_XENTR (Q5M7P8    ), TRD7A_DANRE (A6NAF9    ), TRD7B_DANRE (E7FDW8    )
» more

PDB
[Detailed view]
9 PDB

2LH9; 2LY1; 2LY2; 3RCO; 3S93; 5A48; 5A49; 5CD7; 5CD8

View entry in original PROSITE format
View entry in raw text format (no links)
Direct ScanProsite submission