Entry: PS51652

Forthcoming changes to the profile format
General information about the entry

Entry name [info] AV_MBD
Accession [info] PS51652
Entry type [info] MATRIX
Date [info] AUG-2012 (CREATED); OCT-2013 (DATA UPDATE); AUG-2012 (INFO UPDATE).
PROSITE Doc. [info] PDOC51652
Associated ProRule [info] PRU00985

Name and characterization of the entry

Description [info] Arteriviridae metal-binding (AV MBD) domain profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=67;
/DISJOINT: DEFINITION=PROTECT; N1=6; N2=62;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=2.2115955; R2=0.0074997; TEXT='NScore';
/NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=2882.420898; R2=24.620953; TEXT='HScore';
/CUT_OFF: LEVEL=0; SCORE=972; N_SCORE=9.5; H_SCORE=26814; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=572; N_SCORE=6.5; H_SCORE=16966; MODE=1; TEXT='?';
/DEFAULT: M0=-15; D=-100; I=-100; B1=-1000; E1=-1000; MI=-255; MD=-255; IM=-255; DM=-255;
...
                A    C    D    E    F    G    H    I    K    L    M    N    P    Q    R    S    T    V    W    Y
/I:         B1=0; BI=-255; BD=-255;
/M: SY='G'; M= -56, -80, -67, -68, -87,  71, -72, -90,  43, -89, -80, -55, -73, -62, -64,  68, -60, -83, -84, -79;
/I:         I=-28; MD=-71;
/M: SY='K'; M= -90,-104, -82, -68,-106, -97, -85,-106,  93,-105, -93, -75, -90, -67, -51, -84, -84,-102, -99, -93; D=-28;
/I:         I=-28; MD=-71;
/M: SY='K'; M= -89,-105, -73,  48,-107, -99, -84,-108,  76,-105, -95, -78, -87, -65, -58, -84, -85,-102,-102, -95; D=-28;
/I:         I=-28; MI=-71; IM=-71; DM=-71;
/M: SY='C'; M=  58,  85, -85, -80,  64, -75, -82, -57, -79, -61, -63, -77, -85, -81, -82, -64, -65,  40, -77, -59;
/I:         I=-30; MD=-77;
/M: SY='R'; M= -91,-111, -87, -72,-107,-101, -78,-107, -55,-101, -89, -81, -99,  67,  83, -84, -92,-104,-102, -89; D=-30;
/I:         I=-30; MI=-77; IM=-77; DM=-77;
/M: SY='H'; M=  -8, -21, -21, -19, -12, -30,  53,  13, -19,  -1,   0, -13, -25, -18, -20,  -9,  20,  41, -44,  -7;
/M: SY='C'; M= -14, 128, -33, -34, -24, -29, -33, -31, -29, -21, -22, -20, -44, -37, -36, -16, -14, -18, -54, -35;
/M: SY='T'; M=  19, -17, -13, -15, -26,  31, -19, -21, -13, -24, -18,  -2, -16, -12, -20,  25,  36, -13, -33, -22;
/M: SY='I'; M= -13, -26, -29, -27,  -6, -36,  44,  45, -25,   8,   7, -20, -27, -21, -25, -20,  -9,  38, -36,  -6;
/M: SY='C'; M= -14, 128, -33, -34, -24, -29, -33, -31, -29, -21, -22, -20, -44, -37, -36, -16, -14, -18, -54, -35;
/M: SY='C'; M=  -8,  64,  33, -13, -34,  55, -20, -39, -19, -34, -28,  -1, -24, -19, -27,  -6, -16, -32, -37, -29;
/M: SY='A'; M=  53, -14, -17, -12, -28,  -1, -19, -19, -14, -21, -15, -10, -18,  -9, -18,  25,   0,  -7, -29, -23;
/M: SY='P'; M=  28, -22, -14,  -6, -29, -13, -19, -21,  22, -24, -16,  -9,  40,  -8,  -5,   1,  22, -13, -30, -23;
/M: SY='P'; M=  35, -23, -17, -10, -31,  -7, -20, -22, -14, -27, -18, -14,  61, -12, -21,  19,  -3, -15, -31, -27;
/M: SY='D'; M= -11, -24,  32,  -6, -20, -26, -17,   2,  -4, -11, -10,  -6, -23, -11,  24,  -8,  20,  26, -41, -17;
/M: SY='Y'; M=  27, -19, -21, -18,   1, -17, -11,  -6, -17,  12,  -2, -16, -24, -15, -19,  -2,  20,  -3, -11,  39;
/M: SY='K'; M=  19, -20, -15,  -7, -22, -18, -20,  -6,  32, -15, -10,  -8, -18,  -6,   1,  -1,  22,  14, -31, -18;
/M: SY='S'; M=   7, -16,  -8,  -9, -27,  -2, -11, -26,  -9, -30, -23,   3, -16,  -1, -14,  61,  12, -19, -35, -19;
/M: SY='A'; M=  43, -16, -20, -15, -18,  -7, -19, -10, -17,  10,  -6, -14, -21, -11, -20,  20,  -3,  -4, -28, -18;
/M: SY='C'; M= -14, 128, -33, -34, -24, -29, -33, -31, -29, -21, -22, -20, -44, -37, -36, -16, -14, -18, -54, -35;
/M: SY='G'; M=  -1, -29, -17, -28, -35,  77, -23, -43, -22, -39, -28,  -3, -21, -20, -30,  -2, -21, -37, -26, -30;
/M: SY='M'; M= -11, -24, -28, -28,  -6,  38, -18,   1, -25,  32,  39, -19, -27, -19, -26, -16, -17,  -4, -25, -12;
/M: SY='W'; M=  11, -31,  33,  -8, -14, -13, -18, -27, -13, -28, -25,  26, -25, -12, -19,  -9, -14, -28, 110,  -2;
/M: SY='F'; M= -22, -22, -38, -31,  53, -37, -21,  10, -31,  45,  13, -34, -37, -29, -28, -29, -17,   3, -10,  10;
/M: SY='C'; M= -14, 128, -33, -34, -24, -29, -33, -31, -29, -21, -22, -20, -44, -37, -36, -16, -14, -18, -54, -35;
/M: SY='D'; M= -12, -29,  49,  -5, -22,  40, -15, -19, -17,   9, -13,  -1, -23, -15, -23, -10, -15, -21, -35, -20;
/M: SY='F'; M= -22, -24, -11, -23,  59, -20,  -3, -11, -15,  -7,  -9,  42, -33, -18, -18, -12, -11, -15,  -2,  42;
/M: SY='C'; M= -17, 105, -19, -19, -22, -27,  75, -34, -20, -21, -14,  -7, -33, -17, -19, -14, -16, -26, -55,  -9;
/M: SY='V'; M=  21, -19, -21, -20, -20,  24, -24,   2, -19, -12, -10, -12, -23, -16, -23,  22,  -2,  27, -33, -20;
/I:         I=-28; MD=-71;
/M: SY='P'; M= -45, -65, -38, -32, -56, -46,  45, -55, -38, -55, -41, -37,  58, -36, -43, -39, -39, -58, -64, -37; D=-28;
/I:         I=-28; MI=-71; MD=-71; IM=-71; DM=-71;
/M: SY='Y'; M= -47, -60, -45, -41,  -9, -55, -19, -42, -22, -37, -31, -43, -57, -29,  18, -41, -43, -44, -16,  48; D=-28;
/I:         I=-28; DM=-71;
/M: SY='H'; M= -22, -33,  -6,  -6, -20, -23, 109, -39, -10, -21,  -6,   5, -22,   0,  -4, -11, -20, -38, -56,  11;
/I:         I=-30; MI=0; MD=-77; IM=0; DM=-77;
/M: SY='G'; M= -11, -29, -23, -30,  38,  54, -13, -22, -23, -16, -15, -12, -27, -23, -26, -10, -20, -23,  -4,  38;
/M: SY='H'; M= -22, -33,  -6,  -6, -20, -23, 109, -39, -10, -21,  -6,   5, -22,   0,  -4, -11, -20, -38, -56,  11;
/I:         I=-28; MI=0; MD=-71; IM=0; DM=-71;
/M: SY='P'; M= -29, -56, -33, -22, -58,  17, -32, -51, -26, -51, -38, -27,  35,  28, -30, -24, -35, -52, -46, -44; D=-28;
/I:         I=-28; DM=-71;
/M: SY='C'; M= -17, 105, -19, -19, -22, -27,  75, -34, -20, -21, -14,  -7, -33, -17, -19, -14, -16, -26, -55,  -9;
/M: SY='C'; M= -18,  94, -16, -16, -22, -26,  86, -35, -18, -21, -12,  -4, -31, -12, -15, -13, -17, -28, -55,  -3;
/M: SY='P'; M= -10, -26, -18, -13, -23, -23, -24,  -4, -15, -16, -12, -15,  68, -19, -24,  -4,  35,  14, -37, -24;
/M: SY='V'; M=  -7, -17, -25, -23,  -7, -30, -27,  15, -21,  19,   4, -17, -24, -22, -24,  -6,  35,  37, -37, -14;
/M: SY='S'; M=   2, -16, -13, -13, -20, -11, -17,  -6, -12, -16, -14,  -2, -17,  -8, -17,  44,  32,  14, -37, -18;
/M: SY='L'; M= -13, -20, -29, -24,   2, -28, -19,  10, -25,  49,  13, -25, -32, -17, -24,  10,  -8,   4, -26,  -8;
/I:         I=-26; MD=-65;
/M: SY='F'; M= -38, -40, -46, -39,  63, -43, -33, -18, -39, -12, -19, -40,  34, -47, -40, -36, -30, -24, -12,   7; D=-26;
/I:         I=-26; MI=0; MD=-65; IM=0; DM=-65;
/M: SY='N'; M= -27, -40, -17, -31, -50, -24, -23, -50, -26, -56, -45,  41, -44, -24, -33,  14, -16, -48, -65, -44; D=-26;
/I:         I=-26; DM=-65;
/M: SY='C'; M= -14, 128, -33, -34, -24, -29, -33, -31, -29, -21, -22, -20, -44, -37, -36, -16, -14, -18, -54, -35;
/M: SY='G'; M=  -4, -29, -15, -19, -34,  68, -20, -41,  16, -37, -26,  -2, -19, -12, -12,  -3, -18, -34, -26, -27;
/M: SY='H'; M= -22, -33,  -6,  -6, -20, -23, 109, -39, -10, -21,  -6,   5, -22,   0,  -4, -11, -20, -38, -56,  11;
/M: SY='H'; M=  12, -26,  46,   0, -24, -18,  55, -11, -13, -17, -13,   0, -22,  -9, -16,  -7,  -9,  10, -46, -11;
/M: SY='I'; M=  18, -23, -33, -28,  -7, -28, -34,  49, -26,   8,   6, -25, -25, -24, -30, -14,  -8,  32, -29, -13;
/I:         I=-28; MI=0; MD=-71; IM=0; DM=-71;
/M: SY='G'; M=  -7, -31, -16, -18, -33,  60, -16, -40,   0, -34, -23,  -5, -23,  -8,  40,  -6, -20, -34, -27, -24;
/M: SY='S'; M=   7, -16,  -8,  -9, -27,  -2, -11, -26,  -9, -30, -23,   3, -16,  -1, -14,  61,  12, -19, -35, -19;
/M: SY='T'; M=  -8, -21,  -5,  -9, -27,  23, -12, -24,  24, -27, -18,  32, -17,  -6,  -3,   3,  35, -19, -35, -21;
/M: SY='Y'; M= -12, -26,  -9,  23,   4, -29,  -5,  -3, -10,  -9,  -7, -15, -21,  -7, -15,  -8,  20,  13,  -7,  52;
/M: SY='C'; M= -14, 128, -33, -34, -24, -29, -33, -31, -29, -21, -22, -20, -44, -37, -36, -16, -14, -18, -54, -35;
/M: SY='T'; M=  -6, -21,  30,  -1, -27, -15, -13, -23,  20, -25, -20,   4, -15,  -4,  -4,  26,  37, -16, -38, -19;
/M: SY='M'; M= -10, -26, -23, -13, -15,  20,  -7,  -2, -11,   4,  67, -12, -21,  34, -11, -12, -14,  -7, -26,  -9;
/M: SY='C'; M= -14, 128, -33, -34, -24, -29, -33, -31, -29, -21, -22, -20, -44, -37, -36, -16, -14, -18, -54, -35;
/M: SY='E'; M=  -4, -27,   3,  40, -33, -14,  -6, -30,   1, -28, -20,  -2, -13,  40,  -4,  34,  -1, -25, -31, -20;
/I:         I=-30; MI=0; MD=-77; IM=0; DM=-77;
/M: SY='S'; M=   3, -19, -13, -14, -20,  -8, -16,  13, -13, -16, -13,  -1, -18,  -5, -17,  53,   8,  -4, -33, -16;
/M: SY='P'; M= -19, -44, -19,  -8, -38, -21, -22, -26, -15, -37, -23, -26, 101, -19, -28, -16, -11, -31, -32, -36;
/M: SY='V'; M= -10, -24, -24, -14, -12, -32, -26,  29,  30,   0,   0, -17, -24, -12,  -3, -16,  -7,  37, -31, -14;
/M: SY='Q'; M= -11, -28, -19,  -8, -18,  27, -10,  -8,  -9,  14,  35, -11, -23,  45, -10, -10, -16, -12, -25, -12;
/M: SY='M'; M=  20, -20, -19, -11, -18, -13, -11,  -7,  18,  -4,  50, -10, -19,  -4,  -5,  16,  -4,  -7, -28, -13;
/M: SY='V'; M=  -9, -24,  26, -15, -14,  26, -23,   6, -22,  13,  -3, -12, -27, -20, -26, -13, -10,  27, -35, -17;
/M: SY='P'; M= -18, -35, -10,  -6, -32, -20,  -8, -31,   9, -32, -20,  25,  60,  -2,  49, -11, -11, -30, -33, -23;
/M: SY='T'; M=  -5, -19,  -8,  -4, -25, -16, -14, -21,  34, -24, -17,   1, -14,  -2,   3,  26,  40, -14, -33, -18;
/M: SY='P'; M= -11, -29, -11,  21, -23, -28, -20,   1,  19, -13, -10, -17,  47,  -7,  -7, -14,  -8,  25, -33, -22;
/M: SY='P'; M= -21, -29, -30, -21,  34, -31, -21,   1, -25,  31,   4, -31,  60, -25, -28, -24, -15,  -6, -17,  -3;
/I:         E1=0; IE=-255; DE=-255;
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Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2014_04 which contains 544'996 sequence entries.


Total number of hits 9 in 9 different sequences
Number of true positive hits 9 in 9 different sequences
Number of 'unknown' hits
Number of false positive hits
Number of false negative sequences 0
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 100.00 %

Comments [info]

Matrix type [info] protein_domain
Scaling database [info] reversed
Author [info] CJA_Sigrist
Taxonomic range [info] Eukaryotic viruses
Maximum number of repetitions [info] 1
Feature key [info] DOMAIN
Feature description [info] AV MBD
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
9 sequences

RPOA_EAVBU  (P19811), RPOA_LDVC   (Q06502), RPOA_LDVP   (Q83017), 
RPOA_PRRS1  (Q9YN02), RPOA_PRRSB  (Q8B912), RPOA_PRRSL  (Q04561), 
RPOA_PRRSR  (Q9WJB2), RPOA_PRRSS  (A0MD28), RPOA_SHFV   (Q68772)
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PDB
[Detailed view]
2 PDB

4N0N; 4N0O

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