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PROSITE entry PS51818


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General information about the entry

Entry name [info] HOMEO_PROSPERO
Accession [info] PS51818
Entry type [info] MATRIX
Date [info] 01-OCT-2016 CREATED;
07-APR-2021 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC51818
Associated ProRule [info] PRU01162

Name and characterization of the entry

Description [info] Homeo-Prospero domain profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=159;
/DISJOINT: DEFINITION=PROTECT; N1=6; N2=154;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=3.5287251; R2=0.0090733; TEXT='-LogE';
/NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=6697.4965820; R2=30.4219837; PRIORITY=1; TEXT='Heuristic 0.1%';
/CUT_OFF: LEVEL=0; SCORE=1265; H_SCORE=45181; N_SCORE=15.0; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=328; H_SCORE=16676; N_SCORE=6.5; MODE=1; TEXT='?';
/DEFAULT: M0=-47; D=-100; I=-100; B1=-1000; E1=-1000; MI=-255; MD=-255; IM=-255; DM=-255;
...
                A    C    D    E    F    G    H    I    K    L    M    N    P    Q    R    S    T    V    W    Y
/I:         B1=0; BI=-255; BD=-255;
/M: SY='Q';  M= -53, -91, -28, -39, -63, -19, -72, -88, -49, -68, -68,  15,  11,  51, -51,  28,  20, -81, -98, -76;
/M: SY='E';  M= -26,   5, -35,  50, -80, -55, -75, -80, -55, -87,  14, -36, -51, -57, -17,  38, -23, -61, -97, -43;
/M: SY='T';  M= -43,   1, -81, -82, -86,  42, -85, -20, -20, -47, -20, -70, -52,  -9, -76, -61,  47, -35, -94, -44;
/M: SY='L';  M= -29, -86, -97, -91, -61, -38, -85, -44, -92,  67, -49, -94, -98, -58, -90, -38, -52, -59, -89, -72;
/M: SY='T';  M= -67, -82, -74, -77, -44, -33, -80, -80, -74, -85, -35,  -8,  -6, -55, -65,  43,  68, -53,-100, -82;
/M: SY='P';  M=  -3, -97, -28, -50, -53, -11, -84, -87, -78, -94, -84, -80,  91, -80, -66, -41,  -6, -62, -94, -92;
/M: SY='M';  M= -31,   9, -57, -62, -61, -19, -30, -23, -31, -57,  60,  39, -86,   2, -14,  13, -51, -16, -96, -78;
/M: SY='H';  M= -84, -95, -29, -71, -58, -71, 123, -88, -53, -24, -67, -62, -49, -66, -70, -76, -81, -37,-107, -11;
/M: SY='L';  M= -81, -85, -91, -16, -40, -98, -81, -51, -83,  69,  -9, -93, -65, -79, -16, -88, -55, -50,   0, -68;
/M: SY='K';  M= -78, -40, -73, -22, -88, -52, -43, -12,  64, -73, -76, -67, -82, -57,  60, -46, -74, -81, -89, -78;
/M: SY='K';  M= -77, -50, -55, -58, -89, -85, -72, -87,  84, -25, -75, -65, -38,   2,   4, -54, -72, -85, -87, -79;
/M: SY='A';  M=  73, -43, -51, -59, -88, -41, -81, -80, -61, -42, -75, -74, -51, -71, -15,  -3, -66, -69, -91, -84;
/M: SY='K';  M= -76, -90, -70, -57, -89, -84,   3, -86,  90, -43, -76, -47, -49, -55, -41, -71, -47, -51, -87, -77;
/M: SY='L';  M= -79, -84, -88,  -2, -58, -97, -58, -49, -57,  69,  20, -91, -52, -78, -84, -59, -75, -45, -86, -68;
/M: SY='M';  M= -61, -81, -95, -85, -62, -71, -68, -47, -79,   1, 126, -83, -47, -71, -77, -60, -71, -27, -86, -63;
/M: SY='F';  M= -82, -82, -94, -90, 103, -53, -79, -61, -68, -39, -63, -83, -57, -50, -85, -79,   4, -44, -57, -35;
/M: SY='F';  M= -82, -84, -92, -85,  94, -40, -32, -61, -80,   4, -31, -83, -64,   2, -12, -60, -77, -66, -60, -36;
/M: SY='Y';  M= -29, -90, -39, -80,  28, -86, -56, -67, -61, -53,  -2, -80, -90, -11, -74, -75, -35, -71,  54, 105;
/M: SY='T';  M=   4, -11, -74, -73, -76, -47, -33, -53, -71, -37, -67, -65, -12, -74, -35, -27,  80,  15, -95, -76;
/M: SY='R';  M= -76, -92, -47, -63, -84, -70, -63, -89, -37, -40, -73, -67, -85, -52, 101, -19, -74, -84, -87, -73;
/M: SY='Y';  M= -54, -16, -79, -79, -35, -70,   8, -70, -72, -66, -62, -78, -63, -11, -21, -56, -75, -74, -43, 116;
/M: SY='P';  M= -28, -99, -78, -67, -93, -64, -80, -81, -59, -46, -78, -83, 113, -76, -85, -73, -69, -86, -89, -91;
/M: SY='S';  M= -59,   2, -62, -68, -38, -47, -66, -79, -66, -84, -77,  57, -49,  -8, -71,  74, -13, -25, -95, -76;
/M: SY='S';  M= -45, -76,   2, -23, -84, -63, -70, -80, -67, -69, -79, -56, -12, -60, -72,  88, -29, -36, -94, -77;
/M: SY='N';  M=  24, -76, -62, -68, -53, -59,  12, -76, -66, -67, -73,  65, -32, -28, -72,  31,  29, -28, -95, -76;
/M: SY='M';  M= -71, -80, -52, -82, -59, -88, -75,  22, -78,  22,  64,   4, -34, -76, -52, -74,   8,  30, -83,  11;
/M: SY='L';  M= -76, -79, -31, -83, -52, -94, -77, -30, -86,  78,  -2, -52, -83, -79, -84, -62, -72, -50, -82, -64;
/M: SY='K';  M= -71, -21, -66, -53, -88, -78, -67, -88,  87, -69, -74, -44, -75,  22,  16,  -9, -66, -83, -83, -75;
/M: SY='M';  M=   7, -76, -47, -69, -41, -72, -33, -13, -18, -63,  74, -59, -36,  -7, -70,  42,  36, -42, -87, -50;
/I:         I=-4; MD=-9;
/M: SY='Y';  M= -83,  22, -85, -85,  43, -90, -10, -71, -43, -58, -65, -49, -95, -77, -31, -35, -77, -75, -50, 101; D=-4;
/I:         I=-4; MD=-9;
/M: SY='F';  M= -88, -85, -50, -94, 106, -94, -81, -63, -91, -55, -65, -88, -98,-100, -88, -45, -80, -68,  -5, -33; D=-4;
/I:         I=-4; MD=-9;
/M: SY='P';  M= -65, -45, -77, -49, -92, -78,  15, -57, -75, -56, -80, -77,  97, -74, -84,  29, -67, -66, -94, -68; D=-4;
/I:         I=-4; MI=0; MD=-9; IM=0; DM=-9;
/M: SY='D';  M= -40, -75,  95,  17, -99, -77, -68, -97, -67, -95, -93, -52, -53, -65, -75, -13, -69, -83,-110, -84; D=-4;
/I:         I=-4; DM=-9;
/M: SY='V';  M= -69, -83, -92, -64, -26, -96, -93,  26, -74, -49, -47, -87, -10,  -1, -61, -78, -53,  74, -94, -72; D=-4;
/I:         I=-4; DM=-9;
/M: SY='K';  M= -70, -39, -68, -24, -89, -40, -69, -26,  60, -58, -60, -41, -79,  54,  30, -35, -25, -81, -87, -77; D=-4;
/I:         I=-4; DM=-9;
/M: SY='F';  M= -42, -81, -44, -90, 108, -91, -78, -58, -87, -38, -60, -85, -94, -96, -85, -82, -75, -28, -53, -31;
/M: SY='N';  M= -69, -77, -25, -51, -17, -64, -55, -80, -57, -84, -15,  98, -80,  -5, -10,   3,   1, -81, -93, -23;
/M: SY='R';  M= -49, -50, -31, -56, -84, -48, -63, -86,  58, -82, -12, -61, -21, -34,  83, -66, -41, -81, -83, -72;
/M: SY='C';  M= -30, 106, -67, -72, -56, -35,   6, -79, -33, -48, -71,  59, -86,  -1, -13, -37, -45, -51, -89,  16;
/M: SY='N';  M= -68, -78, -63, -73, -69, -44, -42,  54, -66, -26, -58,  76, -79, -21, -27, -17,  10,  -9, -91, -71;
/M: SY='T';  M= -61, -71, -49, -70, -32, -51,  -4, -40, -67, -69, -39, -46, -69, -70, -74, -23,  99, -14, -94, -70;
/M: SY='S';  M=  53, -17, -69, -66, -26, -32, -71, -76, -16, -78, -36, -32, -74, -61, -39,  67, -53, -54, -85, -73;
/M: SY='Q';  M= -67, -91, -35, -44, -90, -34, -56, -59, -24, -77, -65, -58, -49, 117, -30, -57, -69, -49, -78, -13;
/M: SY='L';  M= -73, -21, -88, -81, -27, -89, -72, -28, -35,  68,  66, -34, -29, -74, -77, -81, -69, -31, -79, -36;
/M: SY='I';  M= -66, -80, -88, -86, -61, -26, -90,  72, -82, -46, -48, -30, -83, -49, -85, -40, -62,  59, -87, -68;
/M: SY='K';  M= -69, -23, -63, -27, -85, -46,  -2, -84,  95, -70, -72, -56, -71, -49, -35, -40, -30, -49, -82, -72;
/I:         I=-11; MI=0; MD=-27; IM=0; DM=-27;
/M: SY='W';  M= -79,-103,-102, -85, -51, -21,  -8, -59, -78, -41, -78, -94, -86, -77, -61, -35, -89, -90, 163, -38;
/M: SY='F';  M= -80, -14, -92, -87, 108, -88, -75, -58, -82, -42, -59, -82, -92, -53, -29, -27, -73, -35,   6, -30;
/M: SY='S';  M= -51, -73, -27, -64, -38, -33, -67, -80, -35, -46, -76, -53, -72, -58, -69,  95, -46, -73, -89, -72;
/M: SY='N';  M= -70, -77, -22, -39, -85, -41, -52, -84, -42, -90, -77, 111, -30, -58, -21, -53, -41, -68,-102, -80;
/I:         I=-30; MD=-77;
/M: SY='F';  M= -81, -80, -93, -89, 107, -42, -42, -58, -85, -28,  -8, -82, -92, -40, -83, -80, -28, -63, -53, -31; D=-30;
/I:         I=-30; MI=-77; IM=-77; DM=-77;
/M: SY='R';  M= -73, -90, -70, -59, -84, -44, -61, -90, -26, -83, -72, -63, -33,   3, 103, -27, -55, -84, -84, -71;
/I:         I=-26; MI=0; MD=-65; IM=0; DM=-65;
/M: SY='E';  M= -68, -23, -25,  95, -34, -52, -63, -86, -40, -80,  -7, -66, -67, -46, -62, -41, -69, -53, -31, -31;
/M: SY='F';  M= -80, -31, -94, -90, 106, -55, -53, -42, -86, -50, -59, -84, -93, -94, -84, -48, -73,  -5, -52,   1;
/M: SY='Y';  M= -70, -86, -82, -81,  53, -87, -55, -38, -36, -32, -57, -80, -91, -18, -72, -75, -61, -20, -44, 106;
/M: SY='Y';  M= -77, -33, -79, -80, -24, -53, -49, -37, -54, -45, -58, -78, -90, -16, -71, -47, -41, -39, -41, 118;
/M: SY='I';  M= -73, -23, -87, -69, -19, -93, -86,  89, -82, -23,   8,   1, -83, -80, -48, -65, -66, -12, -82, -64;
/M: SY='Q';  M= -40, -89, -62, -20, -72, -75,   8, -81, -24, -40, -65,  -8, -20, 110, -35, -58, -26, -82, -82, -68;
/M: SY='M';  M= -65, -75, -86, -78, -56, -62, -64,  32, -37, -26, 127, -74, -76, -64, -39, -45, -61,  -9, -79, -57;
/M: SY='E';  M= -38, -84,  29,  98, -86, -57, -59, -72, -49, -56, -23, -59, -62, -42, -58, -61, -39, -79, -86, -77;
/M: SY='K';  M= -45, -82, -62, -49, -43, -75, -63, -48,  93, -61, -68, -55, -70, -19,  38, -47, -50, -48, -77, -68;
/M: SY='Y';  M= -55, -25, -79, -48,  81, -81, -36, -37, -74, -49,  -9, -22, -86, -74, -73, -18, -39, -63,  40,  90;
/M: SY='A';  M=  85, -68, -74, -47, -77, -54, -75, -39, -69, -42, -63, -69, -73, -29, -73, -26, -57,   7, -82, -75;
/M: SY='R';  M= -72, -88, -69, -58, -80, -82, -59, -50,  -7, -78, -68, -31, -37, -28, 105, -48, -69, -34, -82, -69;
/M: SY='Q';  M= -39, -86, -16, -15, -45, -29, -21, -45, -29, -73, -64, -12, -73, 107, -36, -22, -49,  -9, -18, -66;
/M: SY='A';  M=  78,  15, -75, -69, -73, -61, -74, -10, -70, -22, -63, -43, -75, -42, -74,  -3, -59, -37, -80,  -7;
/M: SY='I';  M= -28, -78, -84, -83, -36, -88, -81,  68, -59,  28, -15,   1, -40, -77, -81, -74, -51,  30, -81, -26;
/M: SY='S';  M=  48, -33, -35, -65, -77, -47, -67, -36, -64, -16, -67,  31, -54, -61, -16,  56, -24, -40, -87, -73;
/M: SY='E';  M= -51, -85,  61,  73, -45, -47, -16, -52, -26, -82, -78,   3, -68,   3, -49,  -8, -46, -81, -91, -75;
/M: SY='G';  M= -11, -81, -70, -50, -86,  88, -76, -52, -72, -86, -77, -31, -75, -71, -18, -56, -42, -42, -81, -82;
/M: SY='V';  M= -30,  26, -88, -83, -38, -88, -86,  48, -80,  -9,   4, -81, -34, -81, -71, -72, -17,  67, -86, -36;
/M: SY='T';  M= -31, -77, -54, -28, -48, -48, -40, -59,  44, -45, -66, -57,  13, -20,  17, -39,  67,  -8, -86, -71;
/I:         I=-15; MD=-39;
/M: SY='N';  M= -36,  -5,  21, -20, -83, -23, -25, -24, -47, -81, -75,  66, -56, -36, -25,  43,  -7, -26, -96, -77; D=-15;
/I:         I=-15; MI=0; MD=-39; IM=0; DM=-39;
/M: SY='P';  M=  34, -67, -39,   6, -81, -67, -73, -64, -16, -40, -69, -69,  52, -52,  16,  -2,   9,   1, -88, -78; D=-15;
/I:         I=-15; DM=-39;
/M: SY='E';  M= -59, -71,  52,  54, -84, -55, -64, -51,  29, -20, -75,  -6, -72, -42,  -8, -16, -15, -78, -91, -76; D=-15;
/I:         I=-15; DM=-39;
/M: SY='D';  M= -15,  -1,  66,  41, -84, -61, -21, -56, -43, -75,  36, -14, -73,  -2, -59,   6, -28, -28, -95, -74; D=-15;
/I:         I=-15; DM=-39;
/M: SY='I';  M= -71, -78, -61, -83, -52, -91, -22,  60, -82,  58, -22, -42, -85, -77, -82, -62, -25,  -3, -80, -61;
/M: SY='H';  M= -29, -54, -48, -57, -42, -61,  55,   4,  -1, -11,   2, -63, -77, -26,  18,  13,  25,  28, -60, -63;
/M: SY='V';  M= -35, -74, -88, -82, -60, -89, -89,  36, -80, -19, -25, -82, -83, -45, -82, -72, -19,  82, -90, -67;
/M: SY='T';  M= -41, -72, -31, -43, -69,   5, -61, -30, -67,   7, -62, -44, -43, -67, -74,  34,  76, -39, -88, -71;
/M: SY='R';  M= -28, -85, -38, -63, -78, -24, -65, -19, -28, -47,   9,  -7,  29, -56,  81, -43, -13, -21, -85, -72;
/M: SY='D';  M= -71, -85,  86,  32, -44, -13, -61, -29, -19, -57, -79,  29, -52, -58, -67, -62, -64, -63, -95, -31;
/M: SY='S';  M= -28,  40, -65, -39, -20, -50,  50, -80, -66, -64, -73, -54, -34, -59, -69,  84, -17, -73, -90, -67;
/M: SY='E';  M= -35, -87, -41,  99, -89, -34, -16, -90, -50, -83, -78, -63, -64,  -2, -59, -38, -67, -83, -28, -78;
/M: SY='L';  M= -72, -77, -90, -83, -38, -92, -77,  44, -82,  71,  -9, -86, -87, -34, -59, -81, -38, -32, -78, -60;
/M: SY='F';  M= -71,   9, -85, -83,  86, -86, -17, -37, -78, -15, -40, -79, -89, -36, -76, -75, -30, -62, -46,  83;
/M: SY='R';  M= -71, -88, -68, -57, -81, -43,  22, -85,  19, -55, -68, -61, -79,   6,  97, -51, -70, -52, -83, -67;
/I:         I=-14; MI=0; MD=-37; IM=0; DM=-37;
/M: SY='A';  M=  40,  22, -73, -70, -72, -45,  12,   4, -70, -46, -60, -21, -75, -13, -74,   0,  40,  33, -89, -71;
/M: SY='L';  M= -73, -18, -45, -81, -24, -91, -20, -21, -83,  81, -17, -87, -90, -77, -81, -82, -69, -38, -78, -59;
/M: SY='N';  M= -36, -76, -48, -10, -78, -42, -14,  -2, -21, -48, -33, 102, -35, -58, -64, -38, -50, -41, -24, -74;
/M: SY='M';  M= -57, -78, -79, -70, -41, -10, -18, -16, -70,  34,  85, -57, -17,  44, -63, -33,  -1, -21, -81, -62;
/M: SY='H';  M= -76, -87, -62, -62, -70, -64, 137, -87, -66, -28, -59, -52, -78, -56, -45, -67, -75, -88,-101,   0;
/M: SY='Y';  M= -77, -88, -78, -80,  18, -84, -47, -64, -45, -61, -58, -78, -90, -69, -70, -27, -71, -69, -37, 122;
/M: SY='N';  M= -70, -76,  -9, -38, -85, -47, -12, -84, -55, -91, -77, 113, -80, -57, -37, -53, -55, -86,-103, -78;
/M: SY='R';  M= -41, -87, -67, -55, -82, -80, -63, -85,  69, -82, -71, -60, -77, -48,  81, -66, -69, -51, -80, -28;
/M: SY='N';  M=  20, -76,  -9, -67, -83,  36, -17, -83, -28, -85, -76,  73, -76, -62, -40,  12, -28, -62, -89, -31;
/M: SY='N';  M= -69, -77, -34, -36, -81, -62,   0, -34, -40, -40, -34, 103, -52,  33, -36, -25, -57, -79, -96, -74;
/M: SY='H';  M= -72, -87,  74,  22, -85, -76,  84, -47, -58, -57, -72, -41, -74,  36, -25, -40, -67, -45, -99, -64;
/M: SY='F';  M= -74, -33, -47, -85,  76, -89, -75,  43, -82,   4,  17, -36, -56, -83, -81, -77, -49,   9, -62,  18;
/M: SY='E';  M= -66, -87, -13,  78, -62, -78, -29, -83,  -2, -80, -56, -60,  -5,  65, -34, -22, -39, -40, -85, -74;
/I:         I=-3; MI=0; MD=-8; IM=0; DM=-8;
/M: SY='V';  M=  -4, -76, -81, -35, -60, -52, -83,  24, -49, -26,  10, -77,  15, -75, -52, -37,  -3,  67, -88, -69;
/M: SY='P';  M= -72, -13, -74, -64, -87, -76, -76, -46, -56, -40, -73, -65, 113, -72, -13, -50, -66, -53, -86, -86;
/M: SY='E';  M= -43, -34,  43,  57, -87, -26, -32, -84, -35, -36, -76, -19, -24,  32, -28,  21, -34, -72, -91, -77;
/M: SY='R';  M= -63,  18, -10,  19, -50, -50,  -7, -84,  -4, -65, -15,  41, -61, -21,  59,   6, -20, -80, -87, -15;
/M: SY='F';  M= -80,  -5, -40, -86,  98, -55, -20, -45, -81,   1, -57, -81, -92, -88, -20, -74, -74, -39, -56,   7;
/M: SY='L';  M= -70,   1, -44, -71, -35, -90, -11,  -3, -53,  41, -29, -79,  -8, -25,  39, -43, -28,   9, -86, -68;
/M: SY='W';  M= -34, -86,  -8,  49, -10, -28, -12, -54, -61, -32, -57, -11, -25,  -7, -39, -33, -16,  10,  51,  14;
/M: SY='V';  M= -16, -58, -89, -66, -67, -90, -92,  15, -54, -49, -55, -64, -39, -84, -85, -73, -11,  79, -96, -73;
/M: SY='V';  M=  31, -79, -84, -79, -74, -68, -71,  13, -77, -44, -62, -78,   5, -77, -34,  -3,   2,  49, -93, -77;
/M: SY='Q';  M= -47, -91, -12,  58, -94, -81, -44, -79, -57, -76, -77, -35,  -7,  75, -51, -11,  -7, -85, -90, -49;
/M: SY='Q';  M= -24, -62, -74,  22,   6, -81, -76,  30, -40, -16, -44, -51, -81,  37, -12, -68,  13,  -4, -85, -43;
/M: SY='T';  M=  17, -56, -73, -68,   2, -76, -79, -73, -71, -75, -72, -63, -75, -55, -48,  -4,  84, -65, -90, -30;
/M: SY='L';  M= -77, -81, -72, -84, -22, -95, -80, -34, -15,  66,   2, -88, -92, -80, -81, -63, -21,  -5, -84, -49;
/M: SY='R';  M= -78, -72, -75, -62, -88, -67, -12, -44,  24, -57, -74, -68, -85,  25,  84, -39, -76, -72, -89, -75;
/I:         I=-22; MI=0; MD=-57; IM=0; DM=-57;
/M: SY='E';  M= -74, -95, -48,  89, -95, -87, -45, -97, -56, -90, -85,  -4, -72,  18, -51, -59, -74, -91,  16, -83;
/M: SY='F';  M= -88, -86,-100, -95, 104, -96, -82, -65, -89, -57, -66, -89, -98, -99, -36, -77, -26, -69,  14, -35;
/M: SY='F';  M= -86, -87, -98, -94,  90, -96,   0, -61, -89, -10, -12, -89, -98, -93, -87, -87, -80, -24,  20,  37;
/M: SY='N';  M= -30, -10,   6,  10, -83, -61, -72, -48,   0, -27,   4,  35, -83, -51,   9,   3, -23, -22,  27, -78;
/M: SY='A';  M=  73, -78, -77, -25, -90, -66, -80, -60, -35, -71, -76, -40, -80, -24, -42,   1, -48, -69, -91, -84;
/M: SY='I';  M= -77, -89, -99, -96, -62,-103, -97,  77, -92,  10, -49, -92, -91, -89, -73, -87, -72,  23, -90, -71;
/M: SY='Q';  M= -24, -89, -79, -35, -80, -84,  -3,  15,  -7, -47, -53, -73, -84,  42,  22,  15, -58,  12,  17, -55;
/M: SY='A';  M=  34,   8, -23, -52, -66,  -5, -48, -67, -57, -32, -27,  17, -83, -58, -69,  26,   6, -71, -95, -49;
/M: SY='G';  M= -61, -72, -76, -19, -97,  78, -83,-101, -76, -98, -88, -29, -84, -65,  -3, -49, -64, -61, -91, -91;
/M: SY='K';  M= -28, -64, -20, -39, -95, -34, -75, -96,  73, -94, -83, -44, -33, -59,  22, -30, -74, -90, -91, -83;
/M: SY='D';  M= -83, -96,  97, -51,-100, -82, -72, -44, -73, -95, -95, -35, -84, -72, -81, -35, -73, -38,-117, -86;
/M: SY='S';  M=  35, -83, -80, -76, -88, -57, -80, -70, -72, -51, -59, -25, -85, -13,   6,  39,  -4,  -2, -97, -83;
/M: SY='D';  M= -81, -97,  67,  56, -99, -87,  17, -99,  -2, -94, -13, -62, -79, -61, -70, -74, -76, -95,-106, -84;
/M: SY='P';  M= -56,-103, -80, -68, -97, -84, -79, -91, -71, -95, -83, -81,  91,  47, -24, -17, -47, -93, -92, -24;
/M: SY='S';  M= -20,   7, -75, -76, -89, -43, -79, -87, -76, -54, -84, -64, -82, -69, -81,  79,   6, -80,-100, -84;
/M: SY='W';  M= -91,-117,-112, -41, -60, -91,-113, -91, -86, -88, -90,-108, -95, -14, -90, -96,-103,-105, 158, -46;
/M: SY='K';  M= -79, -93, -73, -60, -94, -87, -77, -90,  88, -92, -82, -66, -25, -59, -44, -74, -33, -37, -90, -83;
/M: SY='K';  M= -43, -93, -73, -60, -92, -85, -75, -94,  87, -94, -82, -64, -81, -58, -44, -28, -47, -90, -88, -22;
/M: SY='P';  M=  21, -88, -77, -74, -92, -15, -80, -24,  -8, -87, -80,  13,  34,   0, -77,  14,  -2, -48, -96, -87;
/M: SY='I';  M= -82, -95,-102,-100, -16,-106, -99,  87, -95, -51, -54, -92, -91, -92, -98, -89, -32, -39, -87, -19;
/M: SY='Y';  M= -86, -99, -88, -90, -39, -37, -57, -76, -83, -72, -69, -87, -99, -78, -80, -40, -82, -80,  22, 113;
/M: SY='K';  M= -79, -94, -72, -59, -96, -87, -75, -95,  90, -94, -82, -65, -80, -16, -42, -73, -32, -91, -90, -82;
/I:         I=-26; MI=0; MD=-65; IM=0; DM=-65;
/M: SY='V';  M= -76, -88, -92, -92, -71, -98, -11,  44, -88, -60, -46, -17, -92, -89, -92, -79,  19,  49, -97, -10;
/M: SY='I';  M= -82, -96,-100, -97, -70, -47, -99,  79, -89, -35, -57, -92, -28, -89, -12, -89, -77,  -9, -93, -77;
/M: SY='C';  M=  37,  73, -82, -83, -92, -37, -85, -89, -82, -58, -84,   5, -90, -80, -88,  26, -16, -79,-103, -91;
/I:         I=-28; MI=0; MD=-71; IM=0; DM=-71;
/M: SY='R';  M= -24, -97, -79, -66, -95, -90, -75, -95,  55, -68, -19, -72, -88,   2,  61, -76, -80, -90, -93, -83;
/M: SY='M';  M= -86, -89,-100, -94,  13,-100, -81, -56, -90,  52,  56, -39,-100, -86, -36, -77, -81, -63, -84,  -4;
/M: SY='D';  M= -84,-100,  92, -18,-106, -26, -74,-105, -74,-103,-101, -57, -26, -73, -83, -37, -76,-101,-117, -90;
/M: SY='Q';  M= -34, -64,  42, -14,-100, -59, -38, -94, -20, -94, -87, -64, -84,  49, -64,  40, -53, -52,-102, -85;
/M: SY='P';  M= -70, -99,  17,  21, -98, -87, -37, -79, -75, -93, -40, -48,  67, -11, -83, -14,  -3, -27,-102, -77;
/M: SY='I';  M= -44, -90, -98, -96, -11,-101, -97,  49, -91, -15, -60, -21, -96, -92, -37, -87, -75,  46, -96, -75;
/M: SY='P';  M= -85,-109, -85, -75,-101, -86, -88, -93, -80,-102, -89, -31, 102, -83, -44, -39, -78, -98,  27, -96;
/M: SY='E';  M= -63, -99,  29,  74,-101, -91, -74, -98, -24, -95, -91, -71, -34, -22, -51, -32, -77, -48,-102, -91;
/M: SY='Y';  M= -19, -93, -89, -37,  26, -73, -38,  15, -36, -45,   6, -85, -94, -81, -57,  -2, -59, -37, -71,  61;
/M: SY='F';  M= -91, -90,-100, -99,  93, -99, -86, -65, -94, -26, -69,  -7,-103,-102, -93, -65, -83, -18, -66, -44;
/M: SY='K';  M= -83, -97, -77, -64, -94, -90,  -9, -97,  77, -60, -83, -46, -85, -54,  27, -78, -79, -93,  16, -81;
/M: SY='S';  M= -43, -29,  28, -54, -51, -79, -11, -85, -28, -34, -19,  -6, -54, -73, -80,  50,  -4, -49,-102, -47;
/M: SY='P';  M= -28, -98, -33, -50, -95, -84, -38, -86, -80, -33, -39, -34,  81, -43, -64,   3,  -2, -74,-100, -92;
/M: SY='N';  M= -57, -90, -55, -24, -40, -16,  25, -95, -14, -76, -86,  78, -80, -69, -30, -11, -32, -94,-106, -84;
/M: SY='W';  M= -86,  74,-101, -97,  42, -85, -91, -15, -43, -57,  -7, -61, -60, -94, -93, -25, -77, -48,  76,  11;
/M: SY='L';  M= -84, -94, -97, -89, -33, -54, -41, -43, -87,  42,  28, -93,  17, -33, -15, -18, -81, -46, -95, -78;
/M: SY='Q';  M= -27, -99, -13,  37, -27, -67, -77, -94, -37, -92, -20, -17, -62,  52, -31, -34, -20, -65, -99, -75;
/M: SY='Q';  M= -57, -44, -38,  25,-104,  -3,   7, -93, -67, -61, -35, -69, -85,  48,   6, -33, -43, -98,-104, -90;
/M: SY='L';  M= -89, -97,-105,-100, -67, -24, -94, -12, -95,  49, -53, -78, -56, -80, -58, -44, -50, -46, -98, -41;
/M: SY='E';  M=  -8, -43, -83,  27, -52, -33, -52, -80, -31,   0, -81, -68, -25, -61, -80, -18, -84, -21, -65, -62;
/I:         E1=0; IE=-255; DE=-255;
» more

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2024_06 which contains 572'619 sequence entries.


Total number of hits 8 in 8 different sequences
Number of true positive hits 8 in 8 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 0
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 100.00 %

Comments [info]

Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 1
Matrix type [info] protein_domain
Scaling database [info] reversed
Author [info] CJA_Sigrist
Feature key [info] DOMAIN
Feature description [info] Prospero-type homeo
Feature key [info] DOMAIN
Feature description [info] Prospero
Feature key [info] REGION
Feature description [info] Homeo-Prospero
Version [info] 3

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
8 sequences

PROS1_CAEEL (P34522), PROS_DROME  (P29617), PROS_DROVI  (Q9U6A1), 
PROX1_CHICK (Q91018), PROX1_HUMAN (Q92786), PROX1_MOUSE (P48437), 
PROX2_HUMAN (Q3B8N5), PROX2_MOUSE (Q8BII1)
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PDB
[Detailed view]
3 PDB

1MIJ; 1XPX; 2LMD