PROSITE entry PS60008

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General information about the entry

Entry name [info]	CYCLOTIDE_BRACELET
Accession [info]	PS60008
Entry type [info]	PATTERN
Date [info]	01-DEC-2004 CREATED; 01-OCT-2005 DATA UPDATE; 27-MAR-2024 INFO UPDATE.
PROSITE Doc. [info]	PDOC51052

Name and characterization of the entry

Description [info]	Cyclotides bracelet subfamily signature.
Pattern [info]	C-x(0,1)-[ES]-S-C-[AV]-[MFYW]-I-[PS]-x(0,1)-C.

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2024_02 which contains 571'282 sequence entries.

Total number of hits	123 in 122 different sequences
Number of true positive hits	123 in 122 different sequences
Number of 'unknown' hits	0
Number of false positive hits	0
Number of false negative sequences	8
Number of 'partial' sequences	0

Precision (true positives / (true positives + false positives))	100.00 %
Recall (true positives / (true positives + false negatives))	93.89 %

Comments [info]

Taxonomic range [info]	Eukaryotes
Maximum number of repetitions [info]	2
Site [info]	disulfide at position 1
Site [info]	disulfide at position 5
Site [info]	disulfide at position 11
Version [info]	2

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences

122 sequences

CIRA_CHACT  (C0HKH8), CIRA_CHAPA  (P56871), CIRB_CHAPA  (P56879),

CIRC_CHAPA  (P84641), CIRD_CHAPA  (P84642), CIRE_CHAPA  (P84643), 
CIRF_CHAPA  (P84644), CYC10_CLITE (C0HKG2), CYC11_CHACT (C0HKH6), 
CYC11_CLITE (C0HKG3), CYC12_CLITE (G1CWH8), CYC13_CHACT (I0B6G2), 
CYC13_CLITE (C0HJS0), CYC14_CLITE (C0HJS1), CYC17_CLITE (P86849), 
CYC1_CLITE  (G1CWH0), CYC2_CHACT  (I0B6F2), CYC3_CHACT  (C0HKH3), 
CYC4_CLITE  (G1CWH3), CYC5_CHACT  (C0HKH2), CYC5_CLITE  (G1CWH4), 
CYC6_CHACT  (C0HKH1), CYC6_CLITE  (C0HKF9), CYC7_CHACT  (I0B6F4), 
CYC7_CLITE  (G1CWH5), CYC8_CHACT  (I0B6F5), CYC8_CLITE  (G1CWH6), 
CYC9_CHACT  (C0HKH0), CYC9_CLITE  (C0HKG0), CYCA_CLITE  (P86841), 
CYCA_PETHY  (B3EWH5), CYCB_CLITE  (P86842), CYCC_CLITE  (P86843), 
CYCD_CLITE  (P86844), CYCE_CLITE  (P86845), CYCF_CLITE  (P86846), 
CYCG_CLITE  (P86847), CYCH_CLITE  (P86848), CYCJ_CLITE  (P86850), 
CYCK_CLITE  (P86851), CYCL_CLITE  (P86852), CYCM_PETHY  (B3EWH7), 
CYCO_CLITE  (P86901), CYCP_CLITE  (P86902), CYCQ_CLITE  (P86904), 
CYCR_CLITE  (P86903), CYH1_VIOHE  (P58433), CYH2_VIOHE  (P85233), 
CYH4_VIOHE  (P85234), CYHED_PIGEN (C0HLN8), CYHEE_PIGEN (C0HLN9), 
CYHEF_PIGEN (C0HLP0), CYHEG_PIGEN (C0HLP1), CYHEH_PIGEN (C0HLP2), 
CYHEI_PIGEN (C0HLP3), CYHEJ_PIGEN (C0HLP4), CYHEL_PIGEN (C0HLP6), 
CYHEM_PIGEN (C0HLP7), CYLA_PSYLO  (P56872), CYM45_MELRA (A9P3S1), 
CYMC1_MELCT (C0HK35), CYMC4_MELCT (C0HK38), CYMC5_MELCT (C0HK39), 
CYMC6_MELCT (C0HK40), CYMEE_MELDN (C0HKI7), CYMEG_MELDN (C0HKI9), 
CYMEI_MELDN (C0HKJ1), CYMEJ_MELDN (C0HKJ2), CYMEK_MELDN (C0HKJ3), 
CYMEL_MELDN (C0HKJ4), CYMEM_MELDN (C0HKJ5), CYMEN_MELDN (C0HKJ6), 
CYMR1_MELRA (C0HL32), CYMR2_MELRA (C0HL33), CYMR3_MELRA (C0HL34), 
CYO10_VIOOD (P58442), CYO11_VIOOD (P58443), CYO13_VIOOD (Q5USN8), 
CYO17_PSYBR (C0HL23), CYO17_VIOOD (P85180), CYO18_VIOOD (P85181), 
CYO19_VIOOD (P85182), CYO1_VIOOD  (P82230), CYO20_VIOOD (P85183), 
CYO2_PIGEN  (C0HLP8), CYO2_VIOBI  (P85526), CYO2_VIOOD  (P58434), 
CYO3_VIOOD  (P58435), CYO4_VIOOD  (P58436), CYO5_VIOOD  (P58437), 
CYO6_VIOOD  (P58438), CYO7_VIOOD  (P58439), CYO8_VIOOD  (P58440), 
CYO9_VIOBI  (B1NRR2), CYO9_VIOOD  (P58441), CYPLA_PALGU (C0HKJ9), 
CYVA_LEOCM  (P84637), CYVA_VIOCT  (P84635), CYVB_VIOCT  (P84636), 
CYVC_LEOCM  (P84639), CYVD_LEOCM  (P84640), CYVE_VIOBI  (B1NRQ8), 
CYVF_VIOBI  (P85244), CYVG_VIOBI  (P85245), CYVH_VIOBI  (P85246), 
CYVIA_VIODI (C0HKK0), CYVI_VIOBI  (B1NRQ9), CYVJ_VIOBI  (B1NRR0), 
CYVK_VIOBI  (B1NRR1), CYVUA_VIOPU (C0HKK3), CYVUB_VIOPU (C0HKK4), 
CYVUC_VIOPU (C0HKK5), HYFLA_HYBFL (P84647), HYPAA_POMPR (P58445), 
KAB16_OLDAF (P85134), KAB17_OLDAF (P85135), KAB5_OLDAF  (P58456), 
PABR1_PALRI (B3EWF1), VHL1_VIOHE  (P84522), VHR1_VIOHE  (P83937), 
VITA_VIOAR  (P83840), VITA_VIOBI  (B1NRR3)

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Retrieve an alignment of UniProtKB/Swiss-Prot true positive hits:
[Clustal format, color, condensed view] [Clustal format, color]
[Clustal format, plain text] [Fasta format]
Retrieve the sequence logo from the alignment

UniProtKB/Swiss-Prot
False negative sequences

8 sequences

CYCK_PETHY  (B3EWH6), CYGPA_GLOPU (C0HL35), CYGPB_GLOPU (C0HL36),

CYO25_VIOOD (P85188), CYV1_VIOOD  (C0HL14), CYV2_VIOOD  (C0HL15), 
CYV3_VIOOD  (C0HL16), KAB8_OLDAF  (P85175)

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PDB
[Detailed view]

12 PDB

1BH4; 1NBJ; 1VB8; 1ZA8; 2ERI; 2KCG; 2KNM; 2KUX; 7RIH; 7RMQ; 7RN3; 7S55