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A number of proteins, some of which are known to be receptors for growth
factors, have been found to contain a cysteine-rich domain of about 110 to
160 amino acids in their N-terminal part, that can be subdivided into four (or
in some cases, three) modules of about 40 residues containing 6 conserved
cysteines. Proteins known to belong to this family [1,2,3,4] are listed below:
Tumor Necrosis Factor type I and type II receptors (TNFR). Both receptors
bind TNF-α and TNF-β, but are only similar in the cysteine-rich
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