AC   PRU00509;
DC   Domain;
TR   PROSITE; PS51058; ZF_CXXC; 1; level=0
XX
Names: CXXC-type zinc finger
Function: it binds specifically to non-methylated CpG
XX
case (<Feature:PS51058:8=[CH]> and <Feature:PS51058:11=[CH]> and <Feature:PS51058:14=[CH]> and <Feature:PS51058:42=[CH]>) or (<Feature:PS51058:20=[CH]> and <Feature:PS51058:23=[CH]> and <Feature:PS51058:26=[CH]> and <Feature:PS51058:42=[CH]>)
GO   GO:0046872; F:metal ion binding
XX
KW   Metal-binding
KW   Zinc
end case
KW   Zinc-finger
XX
FT   From: PS51058
case (<Feature:PS51058:8=[C]> and <Feature:PS51058:11=[C]> and <Feature:PS51058:14=[C]> and <Feature:PS51058:47=[C]>) and (<Feature:PS51058:20=[C]> and <Feature:PS51058:23=[C]> and <Feature:PS51058:26=[C]> and <Feature:PS51058:42=[C]>)
FT   ZN_FING         from..to
FT                   /note="CXXC-type #"
else case (<Feature:PS51058:8=[CH]> and <Feature:PS51058:11=[CH]> and <Feature:PS51058:14=[CH]> and <Feature:PS51058:47=[CH]>) and (<Feature:PS51058:20=[CH]> and <Feature:PS51058:23=[CH]> and <Feature:PS51058:26=[CH]> and <Feature:PS51058:42=[CH]>)
FT   ZN_FING         from..to
FT                   /note="CXXC-type #; atypical"
else
FT   ZN_FING         from..to
FT                   /note="CXXC-type #; degenerate"
end case
FT   BINDING         8
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /ligand_label="#1"
FT   Group: 1; Condition: [CH]
FT   BINDING         11
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /ligand_label="#1"
FT   Group: 1; Condition: [CH]
FT   BINDING         14
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /ligand_label="#1"
FT   Group: 1; Condition: [CH]
FT   BINDING         20
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /ligand_label="#2"
FT   Group: 1; Condition: [CH]
FT   BINDING         23
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /ligand_label="#2"
FT   Group: 2; Condition: [CH]
FT   BINDING         26
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /ligand_label="#2"
FT   Group: 2; Condition: [CH]
FT   BINDING         42
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /ligand_label="#2"
FT   Group: 2; Condition: [CH]
FT   BINDING         47
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /ligand_label="#1"
FT   Group: 2; Condition: [CH]
XX
Chop: Nter=0; Cter=0;
Size: 6-48;
Related: None;
Repeats: 1-3;
Topology: Undefined;
Example: Q6PCT2;
Scope:
 Eukaryota; Metazoa
Comments: None
XX
# Revision 1.6 2022/11/19
//