{PDOC00048} {PS00049; RIBOSOMAL_L14} {BEGIN} *********************************** * Ribosomal protein L14 signature * *********************************** Ribosomal protein L14 is one of the proteins from the large ribosomal subunit. In eubacteria, L14 is known to bind directly to the 23S rRNA. It belongs to a family of ribosomal proteins which, on the basis of sequence similarities [1], groups: - Eubacterial L14. - Algal and plant chloroplast L14. - Cyanelle L14. - Archaebacterial L14. - Yeast L17A. - Mammalian L23. - Caenorhabditis elegans L23 (B0336.10). - Higher eukaryotes mitochondrial L14. - Yeast mitochondrial Yml38 (gene MRPL38). L14 is a protein of 119 to 137 amino-acid residues. As a signature pattern, we selected a conserved region located in the C-terminal half of these proteins. -Consensus pattern: [GA]-[LIV](3)-x(9,10)-[DNS]-G-x(4)-[FY]-x(2)-[NT]-x(2)-V- [LIV] -Sequences known to belong to this class detected by the pattern: ALL, except for pine L14 and for Acanthamoeba mitochondrial L14. -Other sequence(s) detected in Swiss-Prot: NONE. -Last update: November 1997 / Pattern and text revised. [ 1] Otaka E., Hashimoto T., Mizuta K., Suzuki K. Protein Seq. Data Anal. 5:301-313(1993). -------------------------------------------------------------------------------- PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see https://prosite.expasy.org/prosite_license.html -------------------------------------------------------------------------------- {END}