{PDOC00052} {PS00053; RIBOSOMAL_S8} {BEGIN} ********************************** * Ribosomal protein S8 signature * ********************************** Ribosomal protein S8 is one of the proteins from the small ribosomal subunit. In Escherichia coli, S8 is known to bind directly to 16S ribosomal RNA. It belongs to a family of ribosomal proteins which, on the basis of sequence similarities [1], groups: - Eubacterial S8. - Algal and plant chloroplast S8. - Cyanelle S8. - Archaebacterial S8. - Marchantia polymorpha mitochondrial S8. - Mammalian S15A. - Plant S15A. - Yeast S22 (S24). As a signature pattern, we selected the best conserved region located in the C-terminal section of these proteins. -Consensus pattern: [GE]-x(2)-[LIV](2)-[STY]-[ST]-{A}-x-G-[LIVM](2)-x(4)-[AG]- [KRHAYIL] -Sequences known to belong to this class detected by the pattern: ALL, except for some mitochondrial S8. -Other sequence(s) detected in Swiss-Prot: 1. -Last update: April 2006 / Pattern revised. [ 1] Otaka E., Hashimoto T., Mizuta K. Protein Seq. Data Anal. 5:285-300(1993). -------------------------------------------------------------------------------- PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see https://prosite.expasy.org/prosite_license.html -------------------------------------------------------------------------------- {END}