{PDOC00288} {PS00323; RIBOSOMAL_S19} {BEGIN} *********************************** * Ribosomal protein S19 signature * *********************************** Ribosomal protein S19 is one of the proteins from the small ribosomal subunit. In Escherichia coli, S19 is known to form a complex with S13 that binds strongly to 16S ribosomal RNA. S19 belongs to a family of ribosomal proteins which, on the basis of sequence similarities [1,2], groups: - Eubacterial S19. - Algal and plant chloroplast S19. - Cyanelle S19. - Archaebacterial S19. - Plant mitochondrial S19. - Eukaryotic S15 ('rig' protein). S19 is a protein of 88 to 144 amino-acid residues. Our signature pattern is based on the few conserved positions located in the C-terminal section of these proteins. -Consensus pattern: [STDNQ]-G-[KRNQMHSI]-x(6)-[LIVM]-x(4)-[LIVMC]-[GSD]-x(2)- [LFI]-[GAS]-[DE]-[FYM]-x(2)-[ST] -Sequences known to belong to this class detected by the pattern: ALL. -Other sequence(s) detected in Swiss-Prot: NONE. -Last update: April 2006 / Pattern revised. [ 1] Kitagawa M., Takasawa S., Kikuchi N., Itoh T., Teraoka H., Yamamoto H., Okamoto H. "rig encodes ribosomal protein S15. The primary structure of mammalian ribosomal protein S15." FEBS Lett. 283:210-214(1991). PubMed=2044758; [ 2] Otaka E., Hashimoto T., Mizuta K. Protein Seq. Data Anal. 5:285-300(1993). -------------------------------------------------------------------------------- PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see https://prosite.expasy.org/prosite_license.html -------------------------------------------------------------------------------- {END}