{PDOC00310}
{PS00359; RIBOSOMAL_L11}
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* Ribosomal protein L11 signature *
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Ribosomal protein L11 is one of the proteins from the large ribosomal subunit.
In Escherichia coli, L11 is known to bind directly to the 23S rRNA. It belongs
to a family of ribosomal proteins which, on the basis of sequence similarities
[1,2], groups:

 - Eubacterial L11.
 - Plant chloroplast L11 (nuclear-encoded).
 - Read algal chloroplast L11.
 - Cyanelle L11.
 - Archaebacterial L11.
 - Mammalian L12.
 - Plants L12.
 - Yeast L12 (YL15).

L11 is a protein of 140 to 165 amino-acid residues. As a signature pattern, we
have selected  a  conserved  region located in the C-terminal section of these
proteins. In  Escherichia  coli, the C-terminal half of L11 has been shown [3]
to be  in  an  extended  and  loosely  folded conformation and is likely to be
buried within the ribosomal structure.

-Consensus pattern: [RKN]-x-[LIVM]-x-G-[ST]-x(2)-[SNQ]-[LIVM]-G-x-{M}-[LIVM]-
                    x(0,1)-[DENG]
-Sequences known to belong to this class detected by the pattern: ALL.
-Other sequence(s) detected in Swiss-Prot: 2.
-Last update: April 2006 / Pattern revised.

[ 1] Pucciarelli M.G., Remacha M., Vilella M.D., Ballesta J.P.G.
     "The 26S rRNA binding ribosomal protein equivalent to bacterial
     protein L11 is encoded by unspliced duplicated genes in Saccharomyces
     cerevisiae."
     Nucleic Acids Res. 18:4409-4416(1990).
     PubMed=2167467
[ 2] Otaka E., Hashimoto T., Mizuta K., Suzuki K.
     Protein Seq. Data Anal. 5:301-313(1993).
[ 3] Choli T.
     "Structural properties of ribosomal protein L11 from Escherichia
     coli."
     Biochem. Int. 19:1323-1338(1989).
     PubMed=2483975

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