{PDOC00387}
{PS00464; RIBOSOMAL_L22}
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* Ribosomal protein L22 signature *
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Ribosomal protein L22 is one of the proteins from the large ribosomal subunit.
In Escherichia coli, L22 is known to bind 23S rRNA.  It belongs to a family of
ribosomal proteins  which,  on  the  basis  of  sequence similarities [1,2,3],
groups:

 - Eubacterial L22.
 - Algal and plant chloroplast L22 (in legumes L22  is  encoded in the nucleus
   instead of the chloroplast).
 - Cyanelle L22.
 - Archaebacterial L22.
 - Mammalian L17.
 - Plant L17.
 - Yeast YL17.

As a  signature  pattern,  we  selected  a  conserved region located in the C-
terminal section of these proteins.

-Consensus pattern: [RKQN]-x(2)-{G}-x-[RH]-[GAS]-x-G-[KRQS]-x(8)-{L}-[HDN]-
                    [LIVM]-{A}-[LIVMS]-x-[LIVM]
-Sequences known to belong to this class detected by the pattern: ALL.
-Other sequence(s) detected in Swiss-Prot: 7.
-Last update: April 2006 / Pattern revised.

[ 1] Gantt J.S., Baldauf S.L., Calie P.J., Weeden N.F., Palmer J.D.
     "Transfer of rpl22 to the nucleus greatly preceded its loss from the
     chloroplast and involved the gain of an intron."
     EMBO J. 10:3073-3078(1991).
     PubMed=1915281
[ 2] Madsen L.H., Kreiberg J.D., Gausing K.
     "A small gene family in barley encodes ribosomal proteins homologous
     to yeast YL17 and L22 from archaebacteria, eubacteria, and
     chloroplasts."
     Curr. Genet. 19:417-422(1991).
     PubMed=1913880
[ 3] Otaka E., Hashimoto T., Mizuta K., Suzuki K.
     Protein Seq. Data Anal. 5:301-313(1993).

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