{PDOC00506} {PS00586; RIBOSOMAL_L16_1} {PS00701; RIBOSOMAL_L16_2} {BEGIN} ************************************ * Ribosomal protein L16 signatures * ************************************ Ribosomal protein L16 is one of the proteins from the large ribosomal subunit. In Escherichia coli, L16 is known to bind directly the 23S rRNA and to be located at the A site of the peptidyltransferase center. It belongs to a family of ribosomal proteins which, on the basis of sequence similarities [1], groups: - Eubacterial L16. - Algal and plant chloroplast L16. - Cyanelle L16. - Plant mitochondrial L16. L16 is a protein of 133 to 185 amino-acid residues. As signature patterns, we selected two conserved regions in the central section of these proteins. -Consensus pattern: [KRG]-[KR]-x-[GSAC]-[KRQVA]-[LIVMK]-[WY]-[LIVM]-[KRN]- [LIVM]-[LFY]-[APK] -Sequences known to belong to this class detected by the pattern: ALL. -Other sequence(s) detected in Swiss-Prot: NONE. -Consensus pattern: R-M-G-x-[GR]-K-G-x(4)-[FWKR] -Sequences known to belong to this class detected by the pattern: ALL. -Other sequence(s) detected in Swiss-Prot: NONE. -Last update: December 2004 / Pattern and text revised. [ 1] Otaka E., Hashimoto T., Mizuta K., Suzuki K. Protein Seq. Data Anal. 5:301-313(1993). -------------------------------------------------------------------------------- PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see https://prosite.expasy.org/prosite_license.html -------------------------------------------------------------------------------- {END}