{PDOC00590} {PS00712; RIBOSOMAL_S17E} {BEGIN} ************************************ * Ribosomal protein S17e signature * ************************************ A number of eukaryotic and archaebacterial ribosomal proteins can be grouped on the basis of sequence similarities. One of these families consists of: - Vertebrates S17 [1]. - Drosophila S17 [2]. - Neurospora crassa S17 (crp-3). - Yeast S17a (RP51A) and S17b (RP51B) [3]. - Archaebacterial S17e. These proteins have from 63 (in archebacteria) to 130 to 146 amino acids and are highly conserved. As a signature, we selected a region in the central part of these proteins. -Consensus pattern: [IVDYPKS]-x-[ST]-K-x-[LIVMTF]-[RIKM]-N-x-[IV]-[SA]-G-[FY]- x-[TV]-[HKRA] -Sequences known to belong to this class detected by the pattern: ALL. -Other sequence(s) detected in Swiss-Prot: NONE. -Last update: April 2006 / Pattern revised. [ 1] Chen I.-T., Roufa D.J. "The transcriptionally active human ribosomal protein S17 gene." Gene 70:107-116(1988). PubMed=3240863 [ 2] Maki C., Rhoads D.D., Stewart M.J., Van Slyke B., Roufa D.J. "The Drosophila melanogaster RPS17 gene encoding ribosomal protein S17." Gene 79:289-298(1989). PubMed=2507396 [ 3] Abovich N., Rosbash M. "Two genes for ribosomal protein 51 of Saccharomyces cerevisiae complement and contribute to the ribosomes." Mol. Cell. Biol. 4:1871-1879(1984). PubMed=6092944 -------------------------------------------------------------------------------- PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see https://prosite.expasy.org/prosite_license.html -------------------------------------------------------------------------------- {END}