{PDOC00812} {PS01060; FLIP_1} {PS01061; FLIP_2} {BEGIN} ***************************************************** * Flagella transport protein fliP family signatures * ***************************************************** In Escherichia coli and related proteins the fliP protein probably [1] plays a role in the transport of flagellar proteins. FliP is a protein of about 30 Kd which contains three or four transmembrane regions. Proteins evolutionary related to fliP have been found in a wide range of bacteria (mopC, hrcR, hrpW, spaP, yscR, etc.) and are involved in a variety of signal-peptide independent secretion systems. We developed two signature patterns for this family of proteins. These patterns are located in the C-terminal part of these proteins and overlap with parts of the last two transmembrane regions. -Consensus pattern: [PA]-[AS]-[FY]-x-[LIVT]-[STH]-[EQ]-[LI]-x(2)-[GA]-F- [KREQ]-[IM]-[GV]-[LIF] -Sequences known to belong to this class detected by the pattern: ALL. -Other sequence(s) detected in Swiss-Prot: NONE. -Consensus pattern: P-[LIVMF]-K-[LIVMF](5)-x-[LIVMA]-[DNGS]-G-W -Sequences known to belong to this class detected by the pattern: ALL. -Other sequence(s) detected in Swiss-Prot: NONE. -Last update: December 2004 / Pattern and text revised. [ 1] Malakooti J., Ely B., Matsumura P. "Molecular characterization, nucleotide sequence, and expression of the fliO, fliP, fliQ, and fliR genes of Escherichia coli." J. Bacteriol. 176:189-197(1994). PubMed=8282695 -------------------------------------------------------------------------------- PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see https://prosite.expasy.org/prosite_license.html -------------------------------------------------------------------------------- {END}