{PDOC00831} {PS01082; RIBOSOMAL_L7AE} {BEGIN} ************************************ * Ribosomal protein L7Ae signature * ************************************ A number of eukaryotic and archaebacterial ribosomal proteins can be grouped on the basis of sequence similarities. One of these families consists of: - Vertebrate L7A (SURF3) [1]. - Plant L7A. - Yeast L7A (YL5) (Rp6). - Yeast protein NHP2 [2]. - Yeast hypothetical protein YEL026w. - Bacillus subtilis hypothetical protein ylxQ. - Halobacterium marismortui Hs6. - Methanococcus jannaschii MJ1203. These proteins have 100 to 265 amino-acid residues. As a signature pattern, we selected a conserved region located in the central section. -Consensus pattern: [CAS]-x(4)-[IVA]-P-[FY]-x(2)-[LIVM]-x-[GSQNK]-[KRQ]-x(2)- L-G -Sequences known to belong to this class detected by the pattern: ALL. -Other sequence(s) detected in Swiss-Prot: NONE. -Last update: December 2004 / Pattern and text revised. [ 1] Colombo P., Yon J., Garson K., Fried M. "Conservation of the organization of five tightly clustered genes over 600 million years of divergent evolution." Proc. Natl. Acad. Sci. U.S.A. 89:6358-6362(1992). PubMed=1631131 [ 2] Kolodrubetz D., Burgum A. "Sequence and genetic analysis of NHP2: a moderately abundant high mobility group-like nuclear protein with an essential function in Saccharomyces cerevisiae." Yeast 7:79-90(1991). PubMed=2063628 -------------------------------------------------------------------------------- PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see https://prosite.expasy.org/prosite_license.html -------------------------------------------------------------------------------- {END}