{PDOC00890} {PS01114; GPR1_FUN34_YAAH} {BEGIN} ************************************ * GPR1/FUN34/yaaH family signature * ************************************ The following uncharacterized proteins are evolutionary related: - Yarrowia lipolytica glyxoxylate pathway regulator GPR1. - Yeast protein FUN34. - Yeast hypothetical protein YCR10c. - Yeast hypothetical protein YDR384c. - Fission yeast hypothetical protein SpAC5D6.09c. - Escherichia coli hypothetical protein yaaH. - Methanobacterium thermoautotrophicum hypothetical protein Mth215. They are hydrophobic proteins that seem to contain six transmembrane regions and which could therefore be involved in transport. They have from 188 to 283 amino acids. As a signature pattern, we selected a conserved region located at the N-terminal part of the first potential transmembrane region. -Consensus pattern: N-P-[AV]-P-[LF]-G-L-x-[GSA]-F -Sequences known to belong to this class detected by the pattern: ALL. -Other sequence(s) detected in Swiss-Prot: NONE. -Last update: July 1998 / Pattern and text revised. -------------------------------------------------------------------------------- PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see https://prosite.expasy.org/prosite_license.html -------------------------------------------------------------------------------- {END}