{PDOC00901}
{PS01171; RIBOSOMAL_L21E}
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* Ribosomal protein L21e signature *
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A number of eukaryotic  and  archaebacterial ribosomal proteins can be grouped
on the basis of sequence similarities. One of these families consists of:

 - Mammalian L21 [1].
 - Entamoeba histolytica L21 [2].
 - Caenorhabditis elegans L21 (C14B9.7).
 - Yeast L21E (URP1) [3].
 - Halobacterium marismortui HL31 [4].

These proteins   have   160  (eukaryotes)  or  95  (archebacteria)  amino-acid
residues. As  a  signature  pattern,  we  selected  a  conserved region in the
central part of these proteins.

-Consensus pattern: [GN]-[DEQ]-x-V-x(10,11)-[GVT]-x(2)-[FYHDN]-x(2)-[FY]-x-G-
                    x-[TV]-G
-Sequences known to belong to this class detected by the pattern: ALL.
-Other sequence(s) detected in Swiss-Prot: NONE.
-Last update: April 2006 / Pattern revised.

[ 1] Devi K.R.G., Chan Y.-L., Wool I.G.
     "The primary structure of rat ribosomal protein L21."
     Biochem. Biophys. Res. Commun. 162:364-370(1989).
     PubMed=2751657
[ 2] Petter R., Rozenblatt S., Nuchamowitz Y., Mirelman D.
     "Linkage between actin and ribosomal protein L21 genes in Entamoeba
     histolytica."
     Mol. Biochem. Parasitol. 56:329-333(1992).
     PubMed=1484554
[ 3] Jank B., Waldherr M., Schweyen R.J.
     "Yeast single copy gene URP1 is a homolog of rat ribosomal protein
     gene L21."
     Curr. Genet. 23:15-18(1993).
     PubMed=8428379
[ 4] Hatakeyama T., Kimura M.
     "Complete amino acid sequences of the ribosomal proteins L25, L29 and
     L31 from the archaebacterium Halobacterium marismortui."
     Eur. J. Biochem. 172:703-711(1988).
     PubMed=3350019

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