{PDOC00918} {PS01193; RIBOSOMAL_S8E} {BEGIN} *********************************** * Ribosomal protein S8e signature * *********************************** A number of eukaryotic and archaebacterial ribosomal proteins can be grouped on the basis of sequence similarities [1]. One of these families consists of: - Mammalian S8. - Caenorhabditis elegans S8 (F42C5.8). - Leishmania major S8. - Plant S8. - Yeast S8 (S14) (Rp19). - Archebacterial S8e. These proteins have either about 220 amino acids (in eukaryotes) or about 125 amino acids (in archebacteria). As a signature pattern we selected a conserved stretch which is located in the N-terminal section and which is rich in positively charged residues. -Consensus pattern: [KR]-x(2)-[ST]-G-[GAR]-x(5,6)-[KRHSA]-x-[KRT]-x-[KR]-x- [EA]-[LIMPA]-G -Sequences known to belong to this class detected by the pattern: ALL. -Other sequence(s) detected in Swiss-Prot: NONE. -Last update: December 2004 / Pattern and text revised. [ 1] Engemann S., Herfurth E., Briesemeister U., Wittmann-Liebold B. "Amino acid sequence of the ribosomal protein HS23 from the halophilic Haloarcula marismortui and homology studies to other ribosomal proteins." J. Protein Chem. 14:189-195(1995). PubMed=7662106 -------------------------------------------------------------------------------- PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see https://prosite.expasy.org/prosite_license.html -------------------------------------------------------------------------------- {END}