{PDOC00936} {PS01218; TATC} {BEGIN} ************************* * TatC family signature * ************************* The following proteins have been shown [1] to share regions of similarities: - Escherichia coli hypothetical protein yigU and HI0188, the corresponding Haemophilus influenzae protein. - Bacillus subtilis hypothetical protein ycbT. - Mycobacterium tuberculosis hypothetical protein MtCY49.33c and U2126A, the corresponding Mycobacterium leprae protein. - Synechocystis strain PCC 6803 hypothetical protein sll0194. - Odontella sinensis and Porphyra purpurea chlroplast hypothetical protein ycf43. These proteins have from 245 to 317 amino acids and seem to contain at least six or seven transmembrane regions. As a signature pattern, we selected a conserved region located in the central section of these proteins. -Consensus pattern: Y-x(2)-[FL]-[LIVMAFNT]-[LIVMAFT]-x-[LVSI]-x(4)-[GASF]- x(2)-F-[EQ]-[LIVMFC]-P-[LIVM] -Sequences known to belong to this class detected by the pattern: ALL. -Other sequence(s) detected in Swiss-Prot: NONE. -Last update: April 2006 / Pattern revised. [ 1] Bairoch A., Rudd K.E. Unpublished observations (1996). -------------------------------------------------------------------------------- PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see https://prosite.expasy.org/prosite_license.html -------------------------------------------------------------------------------- {END}