{PDOC00981} {PS01275; EFP} {BEGIN} ********************************* * Elongation factor P signature * ********************************* Elongation factor P (EF-P) [1] is a prokaryotic protein translation factor required for efficient peptide bond synthesis on 70S ribosomes from fMet- tRNAfMet. EF-P is a protein of 21 Kd. It is evolutionary related to yeiP, an hypothetical protein from Escherichia coli. As a signature pattern, we selected a conserved region located in the C- terminal part of these proteins. -Consensus pattern: K-x-[AV]-x(4)-G-x(2)-[LIVT]-x-V-P-x(2)-[LIVC]-x(2)-[GD] -Sequences known to belong to this class detected by the pattern: ALL. -Other sequence(s) detected in Swiss-Prot: NONE. -Last update: December 2004 / Pattern and text revised. [ 1] Aoki H., Adams S.-L., Turner M.A., Ganoza M.C. "Molecular characterization of the prokaryotic efp gene product involved in a peptidyltransferase reaction." Biochimie 79:7-11(1997). PubMed=9195040 -------------------------------------------------------------------------------- PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see https://prosite.expasy.org/prosite_license.html -------------------------------------------------------------------------------- {END}