{PDOC01015}
{PS01311; LGT}
{BEGIN}
*******************************************************
* Prolipoprotein diacylglyceryl transferase signature *
*******************************************************

Prolipoprotein diacylglyceryl  transferase  [1]  is  the bacterial enzyme that
catalyzes the  first  step  in lipoprotein biogenesis, it transfers the n-acyl
diglyceride group  on  what  will  become  the N-terminal cysteine of membrane
lipoproteins. Prolipoprotein  diacylglyceryl  transferase  (gene  lgt)  is  an
integral membrane protein.

As a  signature pattern for this family, we selected a highly conserved region
located in the central part of the protein.

-Consensus pattern: [GI]-R-x-[GA]-N-[FWY]-[LIVMFA]-[NG]-x-E-x(2)-G
-Sequences known to belong to this class detected by the pattern: ALL.
-Other sequence(s) detected in Swiss-Prot: NONE.
-Last update: April 2006 / Pattern revised.

[ 1] Sankaran K., Wu H.C.
     "Lipid modification of bacterial prolipoprotein. Transfer of
     diacylglyceryl moiety from phosphatidylglycerol."
     J. Biol. Chem. 269:19701-19706(1994).
     PubMed=8051048

--------------------------------------------------------------------------------
PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and
distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives
(CC BY-NC-ND 4.0) License, see https://prosite.expasy.org/prosite_license.html
--------------------------------------------------------------------------------

{END}