{PDOC51222} {PS51222; DCD} {BEGIN} ********************** * DCD domain profile * ********************** The DCD domain is found in plant proteins involved in development and cell death. The DCD domain is an ~130 amino acid long stretch that contains several mostly invariable motifs. These include a FGLP and a LFL motif at the N- terminus and a PAQV and a PLxE motif towards the C-terminus of the domain. The DCD domain is present in proteins with different architectures. Some of these proteins contain additional recognizable motifs, like the KELCH repeats or the ParB domain [1]. The predicted secondary structure of the DCD domain is mostly composed of beta strands and confined by an alpha-helix at the N- and at the C-terminus [1]. some proteins known to contain a DCD domain are listed below: - Carrot B2 protein. - Pea Gda-1 protein. - Soybean N-rich protein (NRP). The profile we developed covers the entire DCD domain. -Sequences known to belong to this class detected by the profile: ALL. -Other sequence(s) detected in Swiss-Prot: NONE. -Last update: June 2006 / First entry. [ 1] Tenhaken R., Doerks T., Bork P. "DCD - a novel plant specific domain in proteins involved in development and programmed cell death." BMC Bioinformatics 6:169-169(2005). PubMed=16008837; DOI=10.1186/1471-2105-6-169 -------------------------------------------------------------------------------- PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see https://prosite.expasy.org/prosite_license.html -------------------------------------------------------------------------------- {END}