{PDOC51742}
{PS51742; PPC}
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* PPC domain profile *
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The Plants  and  Prokaryotes  Conserved  (PPC)  domain  contains a hydrophobic
region in the C terminal, and in the case of plants, is often found in several
proteins with  the  AT-hook  motif.  Proteins  with  PPC  domains are found in
Bacteria, Archaea and the plant kingdom [1,2].

The PPC  domain  has a single alpha-helix packed against an antiparallel beta-
sheet, which is formed by five beta-strands (see <PDB:2DT4>) [2]:

Some proteins known to contain a PPC domain are listed below:

 - Plant AT-hook motif nuclear localized protein 1 (AHL1), a matrix-attachment
   region (MAR)  binding  protein  involved in positioning chromatin fibers in
   the nucleus by an AT-hook motif and PPC.
 - Pyrococcus horikoshii putative uncharacterized protein PH0802.
 - Cyanobacteria bifunctional protein GlmU.

The profile we developed covers the entire PPC domain.

-Sequences known to belong to this class detected by the profile: ALL.
-Other sequence(s) detected in Swiss-Prot: NONE.
-Last update: December 2014 / First entry.

[ 1] Fujimoto S., Matsunaga S., Yonemura M., Uchiyama S., Azuma T.,
     Fukui K.
     "Identification of a novel plant MAR DNA binding protein localized on
     chromosomal  surfaces."
     Plant Mol. Biol. 56:225-239(2004).
     PubMed=15604740; DOI=10.1007/s11103-004-3249-5
[ 2] Lin L., Nakano H., Nakamura S., Uchiyama S., Fujimoto S.,
     Matsunaga S., Kobayashi Y., Ohkubo T., Fukui K.
     "Crystal structure of Pyrococcus horikoshii PPC protein at 1.60 A
     resolution."
     Proteins 67:505-507(2007).
     PubMed=17295322; DOI=10.1002/prot.21270

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