{PDOC52001}
{PS52001; AD}
{BEGIN}
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* AD domain profile *
*********************

The AD  domain,  which  may  function  in  RNA-binding  based on its predicted
anticodon-binding fold,  is  found  in the Hezron/Gemin6/Lsm12 protein family.
Members of  this  eukaryotic  protein family have an N-terminal Sm domain (see
<PDOC52002>) followed  by  an  AD  domain  and  are involved in RNA metabolism
[1,2,3].

The profile we developed covers the entire AD domain.

-Sequences known to belong to this class detected by the profile: ALL.
-Other sequence(s) detected in Swiss-Prot: NONE.
-Last update: June 2022 / First entry.

[ 1] Albrecht M., Lengauer T.
     "Novel Sm-like proteins with long C-terminal tails and associated
     methyltransferases."
     FEBS. Lett. 569:18-26(2004).
     PubMed=15225602; DOI=10.1016/j.febslet.2004.03.126
[ 2] Matera A.G., Raimer A.C., Schmidt C.A., Kelly J.A., Droby G.N.,
     Baillat D., Ten Have S., Lamond A.I., Wagner E.J., Gray K.M.
     "Composition of the Survival Motor Neuron (SMN) Complex in Drosophila
     melanogaster."
     G3. (Bethesda). 9:491-503(2019).
     PubMed=30563832; DOI=10.1534/g3.118.200874
[ 3] Patel S., Gunaratne G.S., Marchant J.S., Biggin P.C., Rahman T.
     "NAADP receptors: A one-two."
     Cell. Calcium. 100:102478-102478(2021).
     PubMed=34600271; DOI=10.1016/j.ceca.2021.102478

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