{PDOC52027}
{PS52027; ZF_C2HC_C3H}
{BEGIN}
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* Zinc finger C2HC/C3H-type profile *
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The C2HC/C3H-type  zinc  finger  has  first  been identified in four copies in
Zfp474, a  protein  exclusively  found  in  testis  and  ovary  and thought to
function as  a  germ  cell  specific transcription factor that plays important
roles in  spermatid  differentiation  and  oocyte  development [1]. It is also
found in:

 - Animal proteins of the ZC2HC1 family.
 - Bryophyte  SOSEKI  proteins that locally interpret global polarity cues and
   can influence  cell  division  orientation  to coordinate cell polarization
   relative to body axes.

The profile we developed covers the entire C2HC/C3H-type zinc finger.

-Sequences known to belong to this class detected by the profile: ALL.
-Other sequence(s) detected in Swiss-Prot: NONE.
-Last update: June 2023 / First entry.

[ 1] Zhou C., Li L.Y., Lu G.X.
     "Molecular cloning and character analysis of the mouse zinc finger
     protein gene  Zfp474 exclusively expressed in testis and ovary."
     Yi. Chuan. Xue. Bao. 32:155-162(2005).
     PubMed=15759862

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